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Holiday rentals in Santa Clara

Find and book unique accommodation on Airbnb

Top-rated holiday rentals in Santa Clara

Guests agree: these stays are highly rated for location, cleanliness and more.

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Top guest favourite
A charming apartment building is nestled among lush greenery and tall trees. The exterior features a welcoming porch with railings and is surrounded by tropical plants, creating a serene environment. Natural sunlight filters through the leaves, highlighting the vibrant foliage.
Guest house in Gamboa
4.94 out of 5 average rating, 80 reviews

Gamboa Toucan Apartment casa # 126

Welcome to Gamboa! Only 35 minutes from downtown Panama, Gamboa. Situated in Soberanía National Park and on the shores of the Panama Canal, is a Mecca for Birdwatchers and Nature enthusiasts! Watch the wildlife right from the backyard of your fully equipped apartment. Feel the magic songs of thousands of birds welcoming the twilight of sunrise and dusk in this century old community. Easily explore wildlife on trials through the surrounding old growth jungle and by boat on the Panama Canal.

Top guest favourite
Flat in Veracruz
5 out of 5 average rating, 8 reviews

On the beach. Entire floor with oceanfront terrace

On the beach with direct access to the sea. Open space studio for 2 people. Living room / kitchen / bedroom 1 (Queen) / sofa / armchair / bathroom with shower, dedicated work space. Large, spectacular terrace on the gulf with bathtub convertible into a sofa. Comfortable, elegant, quiet, and safe. Large and fresh tree-lined garden with tropical fauna and flora. Hummingbirds, iguanas, sometimes monkeys and sloths etc ... Gym equipment, small pool. Perfect for recharging your batteries.

Guest favourite
The exterior of a modern house is shown, featuring a covered entrance and a driveway with a parked car. Lush green grass and tropical plants add a touch of greenery, complemented by a palm tree. Large windows offer light to the interior spaces.
Home in Panamá
4.86 out of 5 average rating, 22 reviews

Excellent and affordable house in La Chorrera.

The house is completely private, has parking at the entrance, the master bedroom has a double bed, air conditioning and 65” smart TV and a fully private bathroom, a secondary bedroom with a double bed, air conditioning and 43” smart TV, a secondary bedroom with a twin bed, fan and 32” smart TV, and a shared bathroom. The living-dining room has a sofa, coffee table, TV table with a 32” smart TV, a 4-seat dining room, and a fully-equipped kitchen with a 16-foot refrigerator.

Guest favourite
A scenic view is presented from the balcony, showcasing lush greenery and the town of Gamboa. The Panama Canal and distant hills are visible under a bright sky filled with clouds. A hummingbird feeder is hung nearby, attracting local wildlife.
Cottage in Gamboa
4.78 out of 5 average rating, 55 reviews

Gamboa rainforest lodging

Our restored canal zone home sits on a cul-de-sac in historic Gamboa. It is surrounded by trees and overlooks the town with Panama Canal and passing ships in the distance. An original Damon Kyllo mural adorns one large wall. You will love the balcony, high ceilings, artwork, breezes, and the cacophony of frogs, monkeys, and parrots. This is a great place for birdwatchers and a starting point for exploring the Panama Canal, Soberanía National Park, and the Chagres River.

Guest favourite
An outdoor pool area is featured with modern sun loungers surrounding the illuminated water. Lounge furniture provides space for relaxation, while the skyline of the city is visible in the background against a twilight sky.
Apartment in Marbella
4.94 out of 5 average rating, 64 reviews

Modern and luxurious accommodation in Cinta Costera

Experience the luxurious PH Yoo overlooking the city in this elegant apartment with a king-size bed and floor-to-ceiling windows. Enjoy world-class amenities: swimming pool, gym, squash court, spa, and more. Prime location near tourist areas, restaurants, bars, and shopping malls. Inside the building there are dining options with exclusive discounts and free valet parking. Modern, spacious and sophisticated space for an unforgettable getaway.

Top guest favourite
A private pool area is framed by lush tropical plants and trees, with lounge chairs situated nearby. The pool’s clear blue water reflects the surrounding greenery and the structure in the background, which includes a covered patio for relaxation.
Home in Las Colinas de Caceres de Arraijan
4.98 out of 5 average rating, 222 reviews

Tropical Haven with Yoga Platform

Tropical "open-concept" Airbnb, with a private pool and yoga/meditation platform, located in a typical village, 20 minutes outside the hustle of Panama City, Panama - Central America. This modern contemporary tropical home is located in the hills of Caceres on a 5 acre finca full of tropical trees, birds, and a manicured grounds. Outdoor gas and charcoal barbecue off of back patio with vertical herb garden for perfect relaxation retreat.

Top guest favourite
A well-lit bedroom features a spacious bed with light-colored bedding, complemented by decorative wall art. Natural light enters through large glass doors, which open to a small terrace with greenery. A cozy armchair is positioned nearby, enhancing the room's inviting atmosphere.
Apartment in Santa Ana
5 out of 5 average rating, 24 reviews

King Bed, Creative Design Steps from Casco Viejo

Casco 114 is a stay created by travelers, for travelers. Located in the heart of Santa Ana, the creative district of Panama’s Casco viejo, it offers a king bed, full-size trundle, sofa bed, private terrace, washer/dryer, and unique decor. At PH Casco View: enjoy a saltwater pool, coworking space, stunning views of both the Old Town and the modern city, paid parking, and all the comforts for an unforgettable stay.

Guest favourite
Flat in Panamá
5 out of 5 average rating, 5 reviews

Ocean View on Avenida Balboa

Enjoy breathtaking views, a spectacular oceanfront infinity pool, and direct access to the Poin Panama resort, as well as a variety of dining and bar options for an unparalleled vacation experience. This spacious and cozy apartment is ideal for families, couples or travelers looking for an unforgettable getaway. Book now and start your adventure in this urban oasis!

Top guest favourite
A modern apartment building is presented, featuring a well-maintained pool area in the foreground. Multiple lounge chairs and tables are arranged neatly around the pool, which reflects the blue sky above. The building showcases large windows, enhancing natural light throughout its levels.
Flat in La Chorrera
4.91 out of 5 average rating, 45 reviews

The best getaway place in Panama

Enjoy the charmed Panama from our beautiful apartment in Costa Verde, La Chorrera. 30 minutes away from Panama City and 30 minutes away from tipical Panama provinces. Walk distance to the mall, banks, restaurants, pharmacies, stores and much more. Perfect place for you to enjoy all places of Panama. Relax with the whole family at this peaceful place to stay.

Top guest favourite
A cozy living area is highlighted by a light-colored wooden table placed on a textured rug. Two comfortable chairs face the table, with a small plant centerpiece and books visible. Natural light floods the space through large windows, revealing lush greenery outside.
Loft in Panamá
4.95 out of 5 average rating, 78 reviews

Canal Loft

Apartment on 1st floor, ideal for couples who love good taste, tranquility and comfort. Nearby to the apartment there are trails to the Panama Canal, hills and jungle. Apartment on the 1st Floor, ideal for couples who love good taste, tranquility and comfort. Near the apartment there are trails to the Panama Canal, hills and jungle.

Guest favourite
A bright bedroom features a spacious bed adorned with a patterned blue and white blanket. Natural light floods the room through large windows, which provide a view of the surrounding landscape. A television is mounted on the wall opposite the bed, and wooden accents add warmth.
Apartment in Woodlands
4.95 out of 5 average rating, 65 reviews

Lovely apartment with pool in Panama Pacifico

Take it easy at this unique and tranquil getaway. An apartment located 10 minutes from the city, in the tranquility of a beautiful green area suitable for hiking, cycling or enjoying the outdoors. The apartment is fully equipped so you can enjoy your stay 100%.

Superhost
Home in Brisas del Golf de Arraijan
4.74 out of 5 average rating, 27 reviews

" Casa Esmeralda: Spacious and ideal for families"

Spacious and comfortable family home with 3 bedrooms and 2 bathrooms, ideal for families or groups. Located just 20 minutes from Panama City, it's also very close to banks, pharmacies, supermarkets, restaurants, and more. Just an hour from the beach.

Popular amenities for Santa Clara holiday rentals

  1. Airbnb
  2. Panama
  3. Panamá Oeste
  4. Santa Clara