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Holiday rentals in Santa Cruz County

Find and book unique accommodation on Airbnb

Top-rated holiday rentals in Santa Cruz County

Guests agree: these stays are highly rated for location, cleanliness and more.

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Top guest favourite
A spacious living area is highlighted by large windows allowing natural light. A plush gray couch and a colorful throw blanket create a comfortable seating arrangement, while a decorative plant and natural wood accents add warmth. A cozy fireplace is also visible.
Home in Tubac
5 out of 5 average rating, 61 reviews

Tubac Resort Home!

Perfect location! Walking distance to the Tubac Golf Resort & Spa & the Village of Tubac with great restaurants. Located on a cul-de-sac in the Country Club Estates. This charming home has stunning views from every window. The second bedroom offers an elevated workspace for business, art, or crafts. Close to the Jean Bautista Anza trail for birders, plein air painters, or a hike along the Santa Cruz river. Close to Madera Canyon with over a 100 miles of hiking trails. A tranquil community!

Guest favourite
A charming adobe-style guesthouse features a covered porch with seating areas. Natural stone pathways lead to the entrance, flanked by desert landscaping and potted plants. The exterior showcases warm earth tones with a tile roof, surrounded by open skies and a peaceful atmosphere.
Guest house in Tubac
4.86 out of 5 average rating, 113 reviews

Amazing Casita at the Tubac Resort-Self check-in*

Take it easy at this unique and tranquil getaway in the beautiful and historic Tubac Golf Resort. Located in a quiet neighborhood just a 5 minute walk to resort amenities including, spa, salon, resort shops, and Stables restaurant. Our Guesthouse includes a king bed, Sofa bed, personal driveway to park your car, private entrance, beautiful terrace, fireplace, Smart TV, internet, coffee maker, microwave, and mini refrigerator. Known as a center of art and history, is truly worth the visit.

Top guest favourite
Guest house in Patagonia
4.99 out of 5 average rating, 108 reviews

Dream House

Replenish * Re-calibrate * Reconnect.. Welcome to our little house of dreams! You have found the perfect leaping off point to explore all this region has to offer. Nestled snugly between the Patagonia and Santa Rita mountains, our casita sits at just under 5,000 ft, making it temperature perfect almost year round. Enjoy our 38 acres and private hiking trails right out the front door with endless possibilities for adventure. Recharge, Rejuvenate, and Revel in our cozy, clean, quite space.

Top guest favourite
A brass bell is prominently displayed against a dark sky, capturing attention with its polished surface. It hangs from a metallic arm, showcasing detailed craftsmanship, while the surrounding structure is minimally visible in the foreground.
Flat in Tubac
4.99 out of 5 average rating, 219 reviews

Coolest AirBnB - Unique -100% Solar EV Free Charge

Located in the historic district of the village; a Tubac icon. Drive for free ... charge with my Level 2 solar while you're here; house is 100%, solar. Private, secure, best location, warm weather, fast Internet, new and comfy bed, complete kitchen, high quality AC, quaint, free easy parking, washer/dryer, walled courtyard with a fountain, walk-in shower, light blocking shades. Eight excellent restaurants within 1 mile. An exceptional value, best price, no deposit or cleaning fees

Top guest favourite
A dining area features a long wooden table surrounded by six dark chairs. A large chandelier shaped like a star hangs above the table, casting intricate patterns on the walls. A decorative centerpiece of fresh fruits adds a touch of color.
Home in Tubac
5 out of 5 average rating, 142 reviews

A Tubac Getaway

Amazing luxury vacation rental in beautiful, historic Tubac, Arizona. Located in The Sanctuary neighborhood, this home is within walking distance of either The Village of Tubac or the Tubac Golf Resort. Plenty of nearby activities including hiking, golf, birdwatching, or day trips to southern Arizona. Visit unique shops in The Village of Tubac or the Resort for furnishings, jewelry, or great food at a variety of restaurants. Come see everything that southern Arizona has to offer!

Guest favourite
A hammock is gently draped between two trees, with the fabric partially visible in the foreground. The background features a stunning sunset, casting soft hues across the sky. The landscape is open, with sparse vegetation and rolling hills creating a tranquil environment.
Guest suite in Nogales
4.94 out of 5 average rating, 146 reviews

Patagonia Lake Hideaway

PRIVATE SPACE! $105 p nite NO CLEANING FEES but airbnb charges its own fees. king bed, picture window, sofa, french doors,electric fireplace, tv, Private courtyard&patio, sunrise over Patagonias,sunset behind the Atascosas. Birding paradise.part of Madrean sky Island.Lake minutes away with boat rentals, swimming, fishing, hiking, small beach. Easy travel toTombstone, AZ Trail, Tubac, Kartchner caverns, Patagonia, Mexico, wine and spirit tasting .check in whenever.check out 5pm

Top guest favourite
A refreshing saltwater pool is framed by a spacious deck, lined with comfortable lounge chairs. The surrounding landscape features native plants and offers expansive views of the desert terrain and distant mountains under a dramatic sky.
Cottage in Patagonia
4.97 out of 5 average rating, 129 reviews

Kestrel Cottage at Birdsong Retreat

ATTENTION SUMMER BOOKINGS: Swamp cooler entire cottage and AC wall unit in queen bedroom. We provide fans. With monsoon rains, it’s too humid to use swamp cooler. Cottage priced to reflect the heat. Escape to serene high desert grasslands in Patagonia, AZ, offering 360-degree views at 4,058 feet offering respite from the Phoenix and Tucson heat. Nestled within BirdSong Retreat on 37 acres, the Kestrel Cottage promises luxurious accommodations and a focus on well-being.

Top guest favourite
An open living area features a high, vaulted ceiling with exposed wooden beams. Large windows offer natural light and views of the surrounding trees. A brown sectional sofa surrounds a coffee table, while a blue storage cabinet and a television complete the space. Dining chairs and a table are visible to one side.
Home in Patagonia
4.99 out of 5 average rating, 87 reviews

Patagonia's Private Paradise

$100 PER NIGHT SUMMER IN PATAGONIA IS A WONDERFUL TIME SUMMER DISCOUNT READ OUR REVIEWS BEFORE YOU CHOOSE Patagonia is located high in the SKY ISLANDS of Southeast Arizona. The higher elevation and mountain forests make Patagonia much cooler than the Arizona cities at a lower elevation. Come to Patagonia and enjoy great discounts for longer-term stays at a time of year that many find nice and green. 20% OFF FOR 7 NIGHTS OR MORE 35% OFF FOR 28 DAYS OR MORE

Top guest favourite
The exterior of the apartment features a vibrant yellow adobe wall, accented by a decorative horse motif. A wooden bench sits beneath a window with wrought iron detailing, while potted plants add greenery to the entrance. Rain-soaked surfaces reflect the surrounding colors.
Flat in Nogales
4.94 out of 5 average rating, 242 reviews

Las Hacienditas Large Two-Bedroom Apartment

Located in the beautiful town of Rio Rico. Just a few minutes from the Mexican border and from the art community at Tubac. A few blocks from a beautiful walking trail, gymnasium and several churches. This private apartment has all the amenities you need for a short or long stay. We take all the necessary steps to make sure the space is sanitary by disinfecting all areas and washing all bedding and linens to protect you and your family or guests.

Top guest favourite
Home in Patagonia
4.92 out of 5 average rating, 12 reviews

Peaceful Family Friendly + Fire Pit + Volleyball

Escape to this peaceful desert retreat nestled against the hills of Patagonia. With two bedrooms, a bonus office with daybed, and a spacious living area with pull out bed, the home comfortably hosts families or small groups looking to relax, explore, and enjoy the quiet beauty of Southern Arizona. Spend evenings under the twinkle lights around the fire pit, wake up to views of the hills, or enjoy a friendly match on the volleyball court.

Guest favourite
The guesthouse features a cozy sleeping area with a spacious bed dressed in simple linens. A comfortable sofa is positioned next to a wood bookshelf, which holds various decorative items. A desk and chair provide a dedicated workspace, with natural light filtering through the curtains.
Guest house in Rio Rico
4.87 out of 5 average rating, 376 reviews

Cozy Rio Rico guesthouse with a view

This spacious guesthouse is in an ideal rural setting. Located near the Mexican border, the art community at Tubac, and the old Spanish mission of Tumacacori, there is lots to see and do. (Not to mention many good golf courses.) I am looking forward to your visit! To make your stay both pleasant and sanitary I steam clean floors, sani-wash all linens and towels, and wipe counters, sinks and toilet with sanitizer spray. Rest easy here!

Top guest favourite
A green casita is situated in an open landscape, surrounded by a rustic fence. A gravel driveway leads towards the entrance, with an American flag waving gently overhead. Lush grass and a few scattered trees enhance the rural setting under a clear blue sky.
Home in Sonoita
4.98 out of 5 average rating, 287 reviews

Sky Island Retreat Sonoita, AZ.

Sky Island Retreat is a quiet and peaceful hilltop retreat in which you can relax and enjoy the natural beauty of this historic area. The casita is the original but updated ranch house built in the late 60’s. We have kept much of its original charm while upgrading to modern comfort and conveniences. We are located on a privately gated property just minutes from the heart of Sonoita and Southern AZ’s growing wine country.

Popular amenities for Santa Cruz County holiday rentals