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Holiday rentals in Santa Cruz County

Find and book unique accommodation on Airbnb

Top-rated holiday rentals in Santa Cruz County

Guests agree: these stays are highly rated for location, cleanliness and more.

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Top guest favourite
The large private deck overlooks expansive high desert mountain views. A grill sits ready for use, accompanied by a small potted plant on a metal cart. Lush greenery frames the view, providing a serene outdoor space.
Flat in Sonoita
4.99 out of 5 average rating, 162 reviews

High Desert Wine Country

Take it easy at this tranquil getaway. Breathtaking views, 5000 feet altitude. See wineries or take a day's outing and visit local attractions. Second story apartment is a newly renovated space over hosts' garage (guests must be capable of climbing one flight of spiral stairs). It has a full kitchen (Including dishwasher), full bath (shower only - no tub), nice sized bedroom with queen bed and closet. Second story large private deck. NO DIRT ROADS TO PROPERTY! Adults only and (sorry!) no pets.

Top guest favourite
Guest suite in Patagonia
4.94 out of 5 average rating, 140 reviews

Box T Studio

The Studio is a moderate sized living quarters set up purposely for lounging, relaxing, personal entertainment and rest. Set within the compound of a historical property (The Box T Ranch built in 1902), the studio is the perfect home plate for all your Southern Arizona adventures. It includes an amazing king size bed, comfortable furnishings, a 57" Sony TV, mini fridge, microwave, Keurig, 2 person walk in shower and an AC unit. We are within 5 minute walking distance into town. Perfect getaway!

Guest favourite
A charming adobe-style guesthouse features a covered porch with seating areas. Natural stone pathways lead to the entrance, flanked by desert landscaping and potted plants. The exterior showcases warm earth tones with a tile roof, surrounded by open skies and a peaceful atmosphere.
Guest house in Tubac
4.86 out of 5 average rating, 113 reviews

Amazing Casita at the Tubac Resort-Self check-in*

Take it easy at this unique and tranquil getaway in the beautiful and historic Tubac Golf Resort. Located in a quiet neighborhood just a 5 minute walk to resort amenities including, spa, salon, resort shops, and Stables restaurant. Our Guesthouse includes a king bed, Sofa bed, personal driveway to park your car, private entrance, beautiful terrace, fireplace, Smart TV, internet, coffee maker, microwave, and mini refrigerator. Known as a center of art and history, is truly worth the visit.

Top guest favourite
A saltwater pool is framed by wooden decking and two lounge chairs, offering a serene view of the evening sky painted in shades of orange and pink as the sun sets over the high desert landscape.
Guest house in Patagonia
4.99 out of 5 average rating, 128 reviews

HummingBird Casita at Birdsong Retreat

Your private studio casita at Birdsong Desert Retreat: thoughtfully curated eclectic furnishings & decor, full kitchen, private bath—opening to serene desert views. Welcome with homemade grain-free granola, pancake mix, syrup, coffee & teas. On 40 peaceful acres: 360° vistas of Patagonia, Atascosa Mtns, Coronado Forest, Mt Wrightson & Mexico. Lake 6 min away. Dark-sky compliant—profound starry nights, nature sounds, monsoon storms & rainbows (Jul-Sep) for renewing energy. More at birdsongaz

Guest favourite
A wooden bench with a simple design is positioned against a white wall, featuring a monochromatic framed photograph of a longhorn steer above it. A geometric-patterned pillow in black and white rests on the bench, adding a touch of texture.
Home in Sonoita
4.98 out of 5 average rating, 45 reviews

Rojo Grande Ranch

Rojo Grande Ranch House is a large 4-bedroom 3-bathroom very private home on 20 acres in the heart of beautiful Sonoita. Located directly across the road from 2 popular wineries with beautiful views in all directions. Close to Sonoita town center, wineries, brewery, Patagonia Lake, Sonoita rodeo grounds, Parker Canyon and Cienega Preserve. The perfect house for Winery Vacations, Sonoita Rodeo, Wedding Parties, Wine Festivals, Family Reunions, Lake Trips and Relaxing with family and friends.

Top guest favourite
The exterior of the casita features a welcoming entrance with wrought iron French doors, flanked by two adirondack chairs. Large windows allow natural light to enter, while the rustic structure is covered by a gabled roof, creating an inviting front porch space.
Guest house in Patagonia
4.99 out of 5 average rating, 108 reviews

Dream House

Replenish * Re-calibrate * Reconnect.. Welcome to our little house of dreams! You have found the perfect leaping off point to explore all this region has to offer. Nestled snugly between the Patagonia and Santa Rita mountains, our casita sits at just under 5,000 ft, making it temperature perfect almost year round. Enjoy our 38 acres and private hiking trails right out the front door with endless possibilities for adventure. Recharge, Rejuvenate, and Revel in our cozy, clean, quite space.

Top guest favourite
A brass bell is prominently displayed against a dark sky, capturing attention with its polished surface. It hangs from a metallic arm, showcasing detailed craftsmanship, while the surrounding structure is minimally visible in the foreground.
Flat in Tubac
4.99 out of 5 average rating, 219 reviews

Coolest AirBnB - Unique -100% Solar EV Free Charge

Located in the historic district of the village; a Tubac icon. Drive for free ... charge with my Level 2 solar while you're here; house is 100%, solar. Private, secure, best location, warm weather, fast Internet, new and comfy bed, complete kitchen, high quality AC, quaint, free easy parking, washer/dryer, walled courtyard with a fountain, walk-in shower, light blocking shades. Eight excellent restaurants within 1 mile. An exceptional value, best price, no deposit or cleaning fees

Guest favourite
A hammock is gently draped between two trees, with the fabric partially visible in the foreground. The background features a stunning sunset, casting soft hues across the sky. The landscape is open, with sparse vegetation and rolling hills creating a tranquil environment.
Guest suite in Nogales
4.94 out of 5 average rating, 146 reviews

Patagonia Lake Hideaway

PRIVATE SPACE! $105 p nite NO CLEANING FEES but airbnb charges its own fees. king bed, picture window, sofa, french doors,electric fireplace, tv, Private courtyard&patio, sunrise over Patagonias,sunset behind the Atascosas. Birding paradise.part of Madrean sky Island.Lake minutes away with boat rentals, swimming, fishing, hiking, small beach. Easy travel toTombstone, AZ Trail, Tubac, Kartchner caverns, Patagonia, Mexico, wine and spirit tasting .check in whenever.check out 5pm

Top guest favourite
The exterior of the apartment features a vibrant yellow adobe wall, accented by a decorative horse motif. A wooden bench sits beneath a window with wrought iron detailing, while potted plants add greenery to the entrance. Rain-soaked surfaces reflect the surrounding colors.
Flat in Nogales
4.94 out of 5 average rating, 242 reviews

Las Hacienditas Large Two-Bedroom Apartment

Located in the beautiful town of Rio Rico. Just a few minutes from the Mexican border and from the art community at Tubac. A few blocks from a beautiful walking trail, gymnasium and several churches. This private apartment has all the amenities you need for a short or long stay. We take all the necessary steps to make sure the space is sanitary by disinfecting all areas and washing all bedding and linens to protect you and your family or guests.

Top guest favourite
Home in Patagonia
4.91 out of 5 average rating, 11 reviews

Peaceful Family Friendly + Fire Pit + Volleyball

Escape to this peaceful desert retreat nestled against the hills of Patagonia. With two bedrooms, a bonus office with daybed, and a spacious living area with pull out bed, the home comfortably hosts families or small groups looking to relax, explore, and enjoy the quiet beauty of Southern Arizona. Spend evenings under the twinkle lights around the fire pit, wake up to views of the hills, or enjoy a friendly match on the volleyball court.

Top guest favourite
A green casita is situated in an open landscape, surrounded by a rustic fence. A gravel driveway leads towards the entrance, with an American flag waving gently overhead. Lush grass and a few scattered trees enhance the rural setting under a clear blue sky.
Home in Sonoita
4.98 out of 5 average rating, 285 reviews

Sky Island Retreat Sonoita, AZ.

Sky Island Retreat is a quiet and peaceful hilltop retreat in which you can relax and enjoy the natural beauty of this historic area. The casita is the original but updated ranch house built in the late 60’s. We have kept much of its original charm while upgrading to modern comfort and conveniences. We are located on a privately gated property just minutes from the heart of Sonoita and Southern AZ’s growing wine country.

Top guest favourite
The home is set under two large oak trees, providing a natural shaded environment. A spacious outdoor area is visible, featuring a patio with seating. Surrounding greenery enhances the serene landscape, while a fenced yard adds to the property's secluded feel.
Cottage in Sonoita
4.96 out of 5 average rating, 221 reviews

Under the Oaks

A beautiful setting with a very comfy and clean home. The house offers a screened in porch from which to watch beautiful sunsets and an outdoor Ramada from which to bird watch, grill or enjoy a glass of wine. Under the Oaks is located under 3 enormous oak trees; hence the name. These beautiful trees offer shade, scenery and homes to many varieties of birds.

Popular amenities for Santa Cruz County holiday rentals