
House holiday rentals in Santa Cruz County
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Top-rated house rentals in Santa Cruz County
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Private Getaway: Pandora Ranch House in Arivaca
Pandora is a private remote hacienda located on 20 acres in the high grasslands of the Sonoran Desert with 6 bedrooms, 6 bathrooms, a fully equipped kitchen, a dining room, living room. A well maintained yard with mature trees and charcoal BBQ grills invites to enjoy time outside. Minutes away from the quaint town of Arivaca, Buenos Aires Wildlife Refuge, Arivaca Lake and the Coronado National Forest Pandora offers easy access to hiking, boating,fishing, bird watching and off road exploration.

McFitz Guest Ranch
McFitz Ranch House is fully remodeled and available. Its a 3000 sqft 4 bedroom 3 bathroom w/ two master suites, and game room on 5 acres of beautiful horse property. Close to many attractions such as several wineries, brewery, the Sonoita rodeo grounds, Parker Canyon and Patagonia Lake, La Cienega Preserve and more. This location is ideal for Wedding Parties, Wine vacations, Rodeo, Kentucky Derby Fans, bird watching the Santa Cruz County Fair, hunting seasons or family weekends to the lake

Serenity, Starlink and waking up with bird songs
Wake up to nothing but bird sounds, enjoy morning coffee and the bright stars in dark nights on the covered patio. Contemporary furnished, spacious guest house with beautiful Mountain Views, in rural location, but close vicinity to the towns of Patagonia and Sonoita. Open kitchen - dining area floor plan. The house is set up with all amenities needed by seasonal visitors and remote working professionals. No pets. A small dog may be ok. 1 month or longer preferred. Shorter stays on request.

Desert Oasis Retreat
Relax with the whole family at this beautiful home. Our home has 3 bedrooms. Master suite with large walk-in closet, TV in room. Double sink vanity and a large soaking tub/shower. Second bedroom has a double size bed and walk-in closet, TV in room. Third bedroom has trundle bed (basically two twin beds and large closet. Beautiful living room, comfy family room and all appliances kitchen. Dining area seats 6. Located in the quiet hills of Rio Rico. Valley scenery to enjoy in the evening.

Peaceful SW-style ranch home in wine country
Welcome to our southwestern style ranch home in Sonoita/Elgin, Arizona wine country! Our home is 2,600 square feet and sits on 40 acres with unobstructed views of the beautiful Santa Rita Mountains. Our entire home is available for a wine country getaway. With three bedrooms, two full bathrooms with dual vanities, a half bath, an amazing kitchen, dining, two living spaces, and high-speed Internet, our home is ideal for two or three couples, or a family getaway (crib available for use).

A Tubac Getaway
Amazing luxury vacation rental in beautiful, historic Tubac, Arizona. Located in The Sanctuary neighborhood, this home is within walking distance of either The Village of Tubac or the Tubac Golf Resort. Plenty of nearby activities including hiking, golf, birdwatching, or day trips to southern Arizona. Visit unique shops in The Village of Tubac or the Resort for furnishings, jewelry, or great food at a variety of restaurants. Come see everything that southern Arizona has to offer!

Cottage on Santa Rita | Sundrenched 2 bd/1 bth
Nestled against the hill, this private, sun-filled home is located in the heart of Patagonia, a few quick steps to local businesses. Expansive patios and a cactus garden provide a hidden oasis behind the cottage - an ideal base for exploring the region's wineries, historic towns, gravel cycling, and forests. The home is fully updated, with a generously equipped kitchen, large master bedroom, washer/dryer, flexible second sleeping space, and tasteful minimalist southwest decor.

Peaceful Family Friendly + Fire Pit + Volleyball
Escape to this peaceful desert retreat nestled against the hills of Patagonia. With two bedrooms, a bonus office with daybed, and a spacious living area with pull out bed, the home comfortably hosts families or small groups looking to relax, explore, and enjoy the quiet beauty of Southern Arizona. Spend evenings under the twinkle lights around the fire pit, wake up to views of the hills, or enjoy a friendly match on the volleyball court.

Sky Island Retreat Sonoita, AZ.
Sky Island Retreat is a quiet and peaceful hilltop retreat in which you can relax and enjoy the natural beauty of this historic area. The casita is the original but updated ranch house built in the late 60’s. We have kept much of its original charm while upgrading to modern comfort and conveniences. We are located on a privately gated property just minutes from the heart of Sonoita and Southern AZ’s growing wine country.

Vino & Vibes | 3BR | Hot Tub + Views + Game Room
Escape to Sonoita wine country at this stylish 3BR retreat just minutes from wineries. Soak in the hot tub under star-filled skies, enjoy unparalleled desert views, and unwind in a fun game room with billiards + darts. Thoughtfully designed for couples, friends, or small groups, with cozy beds, a fully stocked kitchen, and a complimentary bottle of wine on arrival. Relax, connect, and make unforgettable memories.

Vince’s Townhome
Stylish 3-Bedroom Stay—Steps from Dining, Shopping & More Enjoy the comfort of a well-equipped home with three cozy bedrooms—all with queen beds —plus a dedicated desk for remote work, a relaxing living area, and in-unit washer/dryer. Located just minutes from popular restaurants, shopping centers, movie theaters, and a nearby medical clinic, this spot offers convenience for every kind of traveler.

Winemaker's Casita in the heart of Wine Country
The perfect casita for your wine tasting getaway! Our cozy space is full of local charm and minutes away from Elgin and Sonoita's many wineries. Centrally located near the Sonoita Crossroads, the Winemaker's Casita is walking distance from local restaurants, including Copper Brothel Brewery and Tia 'Nita's Cantina. Owned + operated by the proprietors of Rune Wines.
Popular amenities for house rentals in Santa Cruz County
House rentals with a pool

Gallo Libre Ranch House in Arivaca, Arizona

Beautifully Bewitching Mansion Indoor Pool

Poolside Escape Near Patagonia

Casa de Anza

Stylish Townhome, 2BD, 2BA-Pool & Gym Access.

Cozy 2 bedroom townhouse, Tubac

Walk to Tubac village and birding/hiking trail!

Valle Verde Ranch House.
Weekly house rentals

Tres Bellotas Ranch Guest House

Starbird Ranch - a piece a quiet solitude

Río Rico Retreat

Comfortable and relaxing place

Modern Elgin Home: Walk to Wineries + Pets Welcome

Sunset Views, EV Charger & Mountain Backdrop

YELLOW HOUSE NEAR THE BORDER

Ranger Trail Camp
Private house rentals

Casa Blanca de Tubac

Sonoita Luxury Wine Country Getaway

Vino y Vacas - Cozy Home - Heart of Wine Tasting

Pastoral Elgin Escape w/ Covered Patio & Grill!

Off The Beaten Path

Peaceful Oasis in The High Desert

LAZYHOG CASITA- 419 Sonoita Avenue

Casita Paz at The Tubac Sanctuary
Destinations to explore
- Rentals with a firepit Santa Cruz County
- Rentals with a fireplace Santa Cruz County
- Rentals with a hot tub Santa Cruz County
- Rentals with pools Santa Cruz County
- Rentals with a washing machine and dryer Santa Cruz County
- Flat rentals Santa Cruz County
- Rentals with outdoor seating Santa Cruz County
- Rentals with a patio Santa Cruz County
- Pet-friendly rentals Santa Cruz County
- House rentals Arizona
- House rentals United States
- Saguaro National Park
- University of Arizona
- Kartchner Caverns State Park
- Arizona-Sonora Desert Museum
- Patagonia Lake State Park
- Tucson Botanical Gardens
- Tumamoc Hill
- Reid Park Zoo
- Titan Missile Museum
- Mission San Xavier del Bac
- Tucson Convention Center
- Tucson Museum of Art
- Rialto Theatre
- Pima Air & Space Museum
- Children's Museum Tucson
- Tumacacori National Historical Park
- Sonoita Vineyards
- Mini Time Machine Museum of Miniatures
- Trail Dust Town
- Rune Wines
- Gene C Reid Park
- Roy P Drachman - Agua Caliente Regional Park
- Tucson Mountain Park
- Tubac Presidio State Historic Park





