
House holiday rentals in Santa Cruz County
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Top-rated house rentals in Santa Cruz County
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Private Getaway: Pandora Ranch House in Arivaca
Pandora is a private remote hacienda located on 20 acres in the high grasslands of the Sonoran Desert with 6 bedrooms, 6 bathrooms, a fully equipped kitchen, a dining room, living room. A well maintained yard with mature trees and charcoal BBQ grills invites to enjoy time outside. Minutes away from the quaint town of Arivaca, Buenos Aires Wildlife Refuge, Arivaca Lake and the Coronado National Forest Pandora offers easy access to hiking, boating,fishing, bird watching and off road exploration.

McFitz Guest Ranch
McFitz Ranch House is fully remodeled and available. Its a 3000 sqft 4 bedroom 3 bathroom w/ two master suites, and game room on 5 acres of beautiful horse property. Close to many attractions such as several wineries, brewery, the Sonoita rodeo grounds, Parker Canyon and Patagonia Lake, La Cienega Preserve and more. This location is ideal for Wedding Parties, Wine vacations, Rodeo, Kentucky Derby Fans, bird watching the Santa Cruz County Fair, hunting seasons or family weekends to the lake

Serenity, Starlink and waking up with bird songs
Wake up to nothing but bird sounds, enjoy morning coffee and the bright stars in dark nights on the covered patio. Contemporary furnished, spacious guest house with beautiful Mountain Views, in rural location, but close vicinity to the towns of Patagonia and Sonoita. Open kitchen - dining area floor plan. The house is set up with all amenities needed by seasonal visitors and remote working professionals. No pets. A small dog may be ok. 1 month or longer preferred. Shorter stays on request.

Camp Cathy
Kick back at this fully furnished hilltop getaway in a quiet gated community above Patagonia. Built for comfort and entertaining, enjoy sweeping mountain views, epic sunsets, and starry nights. The split floor plan offers privacy with 3 bedrooms and 2 baths, TVs in every room, and a dedicated game room for all ages. Fire up the BBQ, lounge in spacious outdoor seating, and stroll into town. Peaceful, private, and perfect for romantic getaways or small group entertaining. Relax, play, repeat!

Peaceful SW-style ranch home in wine country
Welcome to our southwestern style ranch home in Sonoita/Elgin, Arizona wine country! Our home is 2,600 square feet and sits on 40 acres with unobstructed views of the beautiful Santa Rita Mountains. Our entire home is available for a wine country getaway. With three bedrooms, two full bathrooms with dual vanities, a half bath, an amazing kitchen, dining, two living spaces, and high-speed Internet, our home is ideal for two or three couples, or a family getaway (crib available for use).

A Tubac Getaway
Amazing luxury vacation rental in beautiful, historic Tubac, Arizona. Located in The Sanctuary neighborhood, this home is within walking distance of either The Village of Tubac or the Tubac Golf Resort. Plenty of nearby activities including hiking, golf, birdwatching, or day trips to southern Arizona. Visit unique shops in The Village of Tubac or the Resort for furnishings, jewelry, or great food at a variety of restaurants. Come see everything that southern Arizona has to offer!

Cottage on Santa Rita | Sundrenched 2 bd/1 bth
Nestled against the hill, this private, sun-filled home is located in the heart of Patagonia, a few quick steps to local businesses. Expansive patios and a cactus garden provide a hidden oasis behind the cottage - an ideal base for exploring the region's wineries, historic towns, gravel cycling, and forests. The home is fully updated, with a generously equipped kitchen, large master bedroom, washer/dryer, flexible second sleeping space, and tasteful minimalist southwest decor.

Patagonia's Private Paradise
$100 PER NIGHT SUMMER IN PATAGONIA IS A WONDERFUL TIME SUMMER DISCOUNT READ OUR REVIEWS BEFORE YOU CHOOSE Patagonia is located high in the SKY ISLANDS of Southeast Arizona. The higher elevation and mountain forests make Patagonia much cooler than the Arizona cities at a lower elevation. Come to Patagonia and enjoy great discounts for longer-term stays at a time of year that many find nice and green. 20% OFF FOR 7 NIGHTS OR MORE 35% OFF FOR 28 DAYS OR MORE

Peaceful Family Friendly + Fire Pit + Volleyball
Escape to this peaceful desert retreat nestled against the hills of Patagonia. With two bedrooms, a bonus office with daybed, and a spacious living area with pull out bed, the home comfortably hosts families or small groups looking to relax, explore, and enjoy the quiet beauty of Southern Arizona. Spend evenings under the twinkle lights around the fire pit, wake up to views of the hills, or enjoy a friendly match on the volleyball court.

Sky Island Retreat Sonoita, AZ.
Sky Island Retreat is a quiet and peaceful hilltop retreat in which you can relax and enjoy the natural beauty of this historic area. The casita is the original but updated ranch house built in the late 60’s. We have kept much of its original charm while upgrading to modern comfort and conveniences. We are located on a privately gated property just minutes from the heart of Sonoita and Southern AZ’s growing wine country.

Winemaker's Casita in the heart of Wine Country
The perfect casita for your wine tasting getaway! Our cozy space is full of local charm and minutes away from Elgin and Sonoita's many wineries. Centrally located near the Sonoita Crossroads, the Winemaker's Casita is walking distance from local restaurants, including Copper Brothel Brewery and Tia 'Nita's Cantina. Owned + operated by the proprietors of Rune Wines.

Large group getaway - 4 bed w/ updated appliances
Welcome to this new construction 4-bedroom, 2-bathroom home in Rio Rico! Perfect for families or groups. Enjoy an open-concept living space with a gourmet kitchen, granite countertops, and stainless steel appliances. Visit nearby attractions such as Tumacácori National Park, explore nearby Tubac & Nogales AZ, or enjoy family time by the fire pit!
Popular amenities for house rentals in Santa Cruz County
House rentals with a pool

Gallo Libre Ranch House in Arivaca, Arizona

Beautifully Bewitching Mansion Indoor Pool

Poolside Escape Near Patagonia

Casa de Anza

Stylish Townhome, 2BD, 2BA-Pool & Gym Access.

Cozy 2 bedroom townhouse, Tubac

Walk to Tubac village and birding/hiking trail!

Valle Verde Ranch House.
Weekly house rentals

Cosy House: Two bedroom - great WiFi and RO water

Quiet, airy home in Nogales, in the hills.

Cozy stay in wine country at Penelope's Place

Maria's Retreat - Walking distance to the Resort!

Mesquite Haven

Historic Gomez House

Tilted Horse Ranch in the heart of wine country

Ranger Trail Camp
Private house rentals

Tres Bellotas Ranch Guest House

Río Rico Retreat

Comfortable and relaxing place

Modern Elgin Home: Walk to Wineries + Pets Welcome

Sunset Views, EV Charger & Mountain Backdrop

YELLOW HOUSE NEAR THE BORDER

Vince’s Townhome

Casa Rio Rico
Destinations to explore
- Rentals with a fireplace Santa Cruz County
- Pet-friendly rentals Santa Cruz County
- Rentals with a firepit Santa Cruz County
- Rentals with outdoor seating Santa Cruz County
- Flat rentals Santa Cruz County
- Rentals with a washing machine and dryer Santa Cruz County
- Rentals with a hot tub Santa Cruz County
- Rentals with pools Santa Cruz County
- Rentals with a patio Santa Cruz County
- House rentals Arizona
- House rentals United States
- Saguaro National Park
- University of Arizona
- University of Arizona
- Kartchner Caverns State Park
- Arizona-Sonora Desert Museum
- Tumamoc Hill
- Patagonia Lake State Park
- Tucson Botanical Gardens
- Sabino Canyon Recreation Area
- Titan Missile Museum
- Reid Park Zoo
- Mission San Xavier del Bac
- Tucson Museum of Art
- Pima Air & Space Museum
- Tucson Convention Center
- Rialto Theatre
- Children's Museum Tucson
- Sonoita Vineyards
- Mini Time Machine Museum of Miniatures
- Tumacacori National Historical Park
- Trail Dust Town
- Rune Wines
- Mercado San Agustin
- Tubac Presidio State Historic Park





