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Holiday rentals in Santa Cruz de la Sierra

Find and book unique accommodation on Airbnb

Top-rated holiday rentals in Santa Cruz de la Sierra

Guests agree: these stays are highly rated for location, cleanliness and more.

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Guest favourite
A modern dining area features a sleek white table accompanied by two wooden chairs. A cozy bench with soft cushions is positioned against the wall. A large television is mounted nearby, with warm lighting provided by a hanging pendant lamp, creating an inviting space.
Flat in Santa Cruz de la Sierra
4.96 out of 5 average rating, 27 reviews

"Exclusive apartment with balcony in Equipetrol"

If you are looking for a comfortable and elegant place in Santa Cruz, this apartment is in the heart of Equipetrol and is your best choice. A modern 32 m² studio with a king-size bed, work area, equipped kitchen and fast WiFi, created for you to enjoy every moment of your stay. Relax in an exclusive space with air conditioning and a privileged view from the 12th floor of the building. Here you will experience the perfect balance between rest, style and practicality. Your special experience awaits!

Top guest favourite
An expansive rooftop pool is illuminated by soft lighting, reflecting the city skyline at night. Lounge chairs are neatly arranged along the pool's edge, and the sleek wooden deck complements the modern aesthetic of the space.
Flat in Santa Cruz de la Sierra
4.98 out of 5 average rating, 121 reviews

Luxurious and modern apartment. Equipetrol Sky Elite

This luxurious studio is located in the Equipetrol neighborhood, Sky Elite Building, one block from the Los Tajibos Hotel; it represents the perfect combination of exclusivity and first-class amenities in the city of Santa Cruz de la Sierra, surrounded by restaurants, shops, cafes, pharmacies and supermarkets. The building offers more than 3,000 square meters of social areas including a modern gym, extensive swimming pool, barbecue, coworking, private movie theater, sauna and whirlpool.

Guest favourite
Flat in Santa Cruz de la Sierra
5 out of 5 average rating, 18 reviews

Modern Studio in Los Cusis

Discover your ideal retreat in Los Cusis, a peaceful and elegant space designed for your comfort, featuring a balcony with a beautiful green view. Its Central Location places you close to shops, restaurants, and green areas—perfect for making the most of the city. The apartment includes a fully equipped kitchen, Smart TV, AC and Wi-Fi. The building offers free laundry facilities. It’s ideal for working, relaxing, or socializing. Enjoy a comfortable, modern, and stylish stay. Welcome!

Top guest favourite
Green Tower, one of the tallest buildings in Bolivia, showcases modern architecture with its glass facade reflecting the surrounding cityscape. The image captures the building's contemporary design, set against a backdrop of Santa Cruz, featuring both urban and natural elements.
Serviced apartment in Santa Cruz de la Sierra
5 out of 5 average rating, 39 reviews

Green Tower 26th Floor, Luxury, Panoramic Views

Enjoy your stay in the highest Airbnb in Santa Cruz, and in the best building in the city. In the facilities you can enjoy a swimming pool, steam sauna, spectacular views from the 26th floor towards the beautiful Manzana 40 building, the nature of the ecological cordon and the urubo. A few steps from supermarket, restaurants, mall, business center, banks, spa. The tallest and most beautiful restaurants in Santa Cruz, Cielo Skay Bar and Jardin de Asia, are in the same building.

Guest favourite
A modern living space features a blue sofa bed opposite a simple coffee table. A wooden partition separates the sleeping area, which includes a bed with a light blue cover. Colorful wall art depicting birds adds visual interest, while large windows with light curtains provide natural light.
Flat in Santa Cruz de la Sierra
4.88 out of 5 average rating, 152 reviews

Apartment in Equipetrol

Enjoy a quiet, safe, and elegant space in the city's commercial and financial center, Equipetrol Norte. It is located in front of Green Tower, steps from Manzana 40 and the Equipetrol Business Center. A two-minute walk from Hipermaxi and Fidalga supermarkets, pharmacies, and three minutes from the country's largest and most modern shopping mall: Ventura Mall Direct access to cafes, bars, international franchises, and the city's best restaurants without having to drive.

Guest favourite
A contemporary entryway featuring sleek, metallic walls and smooth marble flooring. A minimalist reception desk with soft ambient lighting displays the name 'NUU.' A large potted plant adds a touch of greenery, while well-placed lighting creates a bright atmosphere.
Flat in Santa Cruz de la Sierra
4.95 out of 5 average rating, 55 reviews

apartment with an excellent view

Apartment located in the Equipetrol area. Located on the 13th floor, you'll enjoy stunning views in a comfortable and elegant atmosphere. This apartment has two bedrooms and two bathrooms, ideal for families or groups. It's fully equipped to make you feel at home. Among the building's amenities, you will find a cinema, a swimming pool, a barbecue area, an equipped gym, a playground, and parking for visitors. Easy access to restaurants, shops, and attractions.

Guest favourite
A modern sitting area is presented, featuring a gray sofa adorned with decorative cushions and a yellow accent chair. A round coffee table holds a small floral arrangement. Colorful artwork hangs on the wall above, complementing the patterned area rug beneath.
Apartment in Santa Cruz de la Sierra
4.9 out of 5 average rating, 137 reviews

Magnificent Apartment Exclusive Area Equipetrol

Spectacular apartment in the most privileged area of Santa Cruz. In addition to having shops, luxury restaurants, and shopping centers nearby. Bicycles and Electric Scooters with the Mobi App. Fully furnished apartment equipped with the essentials for a pleasant stay. Access to a swimming pool overlooking the city, co-work, conference room, entertainment room, poker table, barbecues, and outdoor areas with a beautiful view of Equipetrol, all on the 8th floor.

Guest favourite
A tranquil studio space features a spacious bed dressed with light linens and decorative pillows. A cozy seating area includes a dark grey sofa and a round wooden coffee table. Natural light streams through a large window draped with light curtains, highlighting a wall accentuated with soft textures.
Apartment in Santa Cruz de la Sierra
4.87 out of 5 average rating, 262 reviews

Quiet Monoenvironment in Equipetrol

Enjoy the simplicity of this quiet studio in the heart of Equipetrol, where you can be close to restaurants, supermarkets, squares, churches, the business center if you come for work in the same way. In your leisure time, the studio has Wify, TV, Netflix, kitchen, microwave, oven, refrigerator and everything you need to be comfortable inside the building, since in the social areas you can enjoy the pool, churrasqueras, game room and coWork

Guest favourite
Flat in Santa Cruz de la Sierra
4.9 out of 5 average rating, 128 reviews

Beautiful 1-bedroom apartment

One-bedroom apartment, perfect for your next stay in Santa Cruz de la Sierra! Centrally located a few steps from Equipetrol, the city's commercial, business and social center. The unit has a cozy space that offers all the necessary amenities for a comfortable and memorable stay. It includes a service area, washer and dryer, iron, coffee maker, dishes, bed linens, 2 55” smart TVs with cable, Netflix, and a sofa bed. Reserve now!

Guest favourite
A modern bedroom features a spacious bed with light-colored bedding and decorative pillows. Wooden paneling creates a warm aesthetic, complemented by wall-mounted plants. Natural light enters through floor-to-ceiling windows, and a small bedside lamp offers a soft glow.
Apartment in Santa Cruz de la Sierra
4.94 out of 5 average rating, 129 reviews

Modern Studio in the center of Equipetrol

We offer you a comfortable stady with everything you may need, in this modern and new place with our top quality service. This place is fully furnished and has a beautiful view. Is located in the best area from Santa Cruz, and also near of fancy restaurants, malls and business area. You can have access to building's social areas like: co-work zone, pool, steakhouse and laundry. (pics)

Guest favourite
Flat in Santa Cruz de la Sierra
5 out of 5 average rating, 5 reviews

Luxury & 360° View in the Heart of Equipetrol

Enjoy a modern apartment in the heart of Equipetrol, on the 14th floor with an incredible panoramic view of Santa Cruz. The building offers luxurious social areas and an exclusive private paddle tennis court, the trendy sport. The apartment is fully equipped with luxury furniture and all the necessary amenities, with every detail thought out for business or leisure trips.

Guest favourite
Apartment in Santa Cruz de la Sierra
5 out of 5 average rating, 8 reviews

Beautiful Apartment In Equipetrol

This unique place is located in Equipetrol; an exclusive, quiet, and safe area of Santa Cruz. It has all the comforts for a pleasant stay, whether for leisure or work trips (wifi and work area). It is 2 minutes from the Ventura Mall and Av. San Martín, where you will find restaurants, cafes, clothing stores, financial institutions, etc.

Popular amenities for Santa Cruz de la Sierra holiday rentals

Frequently Asked Questions

  • What are the best places to stay in Santa Cruz de la Sierra?

    Santa Cruz de la Sierra has stays in lively neighborhoods like Equipetrol, known for dining and nightlife, and around the city center near plazas and shops. Guests often appreciate areas with leafy streets, local cafes, and easy access to cultural sites.

  • What are the best things to do in Santa Cruz de la Sierra with kids?

    Families can explore city parks, interactive museums, and local zoos featuring native wildlife. Playgrounds and green spaces in residential neighborhoods add opportunities for outdoor fun.

  • What are some of the best things to do in Santa Cruz de la Sierra?

    Discover central plazas, explore Museo de Historia Natural Noel Kempff Mercado, and wander bustling traditional markets. The city also has botanical gardens, art spaces, and vibrant street life.

  • How is the weather in Santa Cruz de la Sierra?

    Santa Cruz de la Sierra generally has warm, humid conditions year-round, with wetter spells in certain months and a tropical atmosphere. Lightweight clothing and sun protection are often suggested, especially for daytime outings.

  • What are the best places to visit in Santa Cruz de la Sierra?

    Explore Plaza 24 de Septiembre, admire local art at Museo de Arte Contemporáneo, and stroll the city’s botanical gardens. Markets and lively pedestrian zones add extra color to the experience.

  • What are some hiking trails in Santa Cruz de la Sierra?

    Santa Cruz de la Sierra has nature reserves and eco-parks where visitors can follow shaded trails amidst tropical plants and birds. Urban green spaces and parks also provide pathways for relaxed walks.

  • What are some family activities we can do in Santa Cruz de la Sierra?

    Families frequently explore city zoos, botanical gardens, interactive museums, and open-air playgrounds. Participating in local craft workshops or tasting fresh fruit at traditional markets brings a sense of discovery.

  • What are some of the best day trip ideas from Santa Cruz de la Sierra?

    Day trips often include exploring nature reserves, visiting Jesuit mission towns, or discovering small communities with locally rooted traditions. Eco-parks around the city provide hiking, birdwatching, and opportunities to connect with regional culture.

  • Are there any pet friendly accommodations available in Santa Cruz de la Sierra?

    Santa Cruz de la Sierra has pet-friendly vacation rentals in neighborhoods like Equipetrol, Urbarí, and around the city center. Many stays include access to green spaces and parks for walks with your pet.

  • What are some local tips for visiting Santa Cruz de la Sierra?

    Locals appreciate lightweight clothes for the heat, insect repellent, and comfortable shoes for exploring urban sights. Trying locally grown fruits at traditional markets is frequently suggested, and learning some Spanish phrases adds ease to your experience.

  • What is Santa Cruz de la Sierra known for?

    Santa Cruz de la Sierra is known for its lively main plaza, tropical botanical gardens, and dynamic blend of Indigenous and European traditions. The city’s vibrant markets, local cuisine, and arts scene are frequently highlighted.

  • What are the best hidden gems to explore in Santa Cruz de la Sierra?

    Around Santa Cruz de la Sierra, visitors often discover small artisan shops, tranquil eco-parks, and street murals tucked in residential neighborhoods. Community-run cafés and weekend craft markets add unique flavor.

  • What are the best foods to try in Santa Cruz de la Sierra?

    Local favorites include salteñas, sonso de yuca, and traditional dishes made from corn, plantain, and tropical fruits. Refreshing drinks such as mocochinchi and locally roasted coffee are often recommended.

  • What should I bring for a trip to Santa Cruz de la Sierra?

    Pack lightweight clothing, sun protection, insect repellent, and comfortable shoes for walking. Bringing a reusable water bottle and rain jacket can add convenience, especially if you plan outdoor excursions.

  • What is the nightlife in Santa Cruz de la Sierra like?

    Santa Cruz de la Sierra has lively nightlife, with bars and clubs frequently suggested around the Equipetrol neighborhood. In the city center, you can explore relaxed venues featuring live music, local cocktails, and outdoor patios.

  • What are the most popular events or festivals in Santa Cruz de la Sierra?

    Santa Cruz de la Sierra has celebrated cultural festivals, Carnaval, and regional fairs throughout the year. Music, dance, and food events are frequently suggested, especially around holidays and community celebrations.

  • Are there family friendly vacation rentals in Santa Cruz de la Sierra?

    Family-friendly vacation rentals can be found in Equipetrol, Urbarí, and the city center, many with spacious layouts and access to parks or play areas. Hosts often provide amenities for children to make visits comfortable.

  • When is the best time to visit Santa Cruz de la Sierra?

    Visitors often prefer the drier months for outdoor activities and exploring city sights, while some enjoy the lush greenery during wet seasons. Popular festivals and pleasant evenings draw many travelers throughout the year.

Quick stats about holiday rentals in Santa Cruz de la Sierra

  • Total holiday rentals

    Explore 4,570 holiday rentals in Santa Cruz de la Sierra

  • Nightly prices starting at

    Santa Cruz de la Sierra holiday rentals start at $13 SGD per night before taxes and fees

  • Verified guest reviews

    Over 55,490 verified reviews to help you choose

  • Family-friendly holiday rentals

    1,260 properties offer extra space & child-friendly amenities

  • Pet-friendly holiday rentals

    Find 1,180 rentals that welcome pets

  • Holiday rentals with a pool

    3,160 properties feature pools

  • Rentals with dedicated workspaces

    2,590 properties have a dedicated workspace

  • Wifi availability

    4,240 of Santa Cruz de la Sierra holiday rentals include wifi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi and Pool across Santa Cruz de la Sierra rentals

  • 4.7 Average rating

    Santa Cruz de la Sierra stays receive an average rating of 4.7 out of 5 from guests

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