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Guest house holiday rentals in Santa Cruz de la Sierra

Find and book unique guest house rentals on Airbnb

Quick stats about guest house rentals in Santa Cruz de la Sierra

  • Total holiday rentals

    Explore 40 holiday rentals in Santa Cruz de la Sierra

  • Nightly prices starting at

    Santa Cruz de la Sierra holiday rentals start at $13 SGD per night before taxes and fees

  • Verified guest reviews

    Over 320 verified reviews to help you choose

  • Pet-friendly holiday rentals

    Find 10 rentals that welcome pets

  • Rentals with dedicated workspaces

    10 properties have a dedicated workspace

  • Wifi availability

    30 of Santa Cruz de la Sierra holiday rentals include wifi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi and Pool across Santa Cruz de la Sierra rentals

Top-rated guest house rentals in Santa Cruz de la Sierra

Guests agree: these guest house rentals are highly rated for location, cleanliness and more.

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A multi-story building is showcased, featuring a distinctive red facade with decorative archways. Balconies extend from the upper floors, providing outdoor space. The ground level houses various storefronts, while utility poles and street signs are visible, indicating a lively urban environment.
Guest house in Santa Cruz de la Sierra
4.36 out of 5 average rating, 14 reviews

Cozy family home in Santa Cruz de la Sierra

Family house of 320 square meters, on the second floor, with all the household goods and linen, wonderful views from its 30-meter terrace. Ideal for families who want to have a quiet stay of any duration in the City of Santa Cruz de la Sierra. Very well connected with several bus lines that lead to the entire city and surroundings and very close to the Cotoca Sanctuary. Nearby you will find all kinds of services, breakfasts, meals, markets, shops, etc.

A spacious common area features comfortable seating arrangements with a mix of sofas and chairs. A central table is set with placemats, while a ceiling fan and air conditioning unit contribute to a comfortable environment. Light filters through large windows, enhancing the welcoming feel.
Guest house in Santa Cruz de la Sierra

Spacious house with a patio and parking

Guest house, with large patio and grill (churrasquera), in a very quiet area. Air conditioning in all rooms, water heater (hot water), Wi-Fi, spacious living room. Suite with private bathroom. Shared bathroom, sofa bed and large sofa on the ground floor. (Up to 4 people can sleep comfortably) Address: km 8, Barrio 14 de Agosto, Calle 3 Between double track la guardia and radial 17 and a half

Superhost
Private room in Centro
4.89 out of 5 average rating, 9 reviews

Room in the center, two minutes from everything!

Experience staying in the heart of Santa Cruz, just 3 blocks from the main square. Our bright and cozy room awaits you in a safe and lively area: museums, cafes, bars, shops and historical corners are within walking distance. Ideal for those seeking comfort, style, and an unbeatable location. With WiFi, details designed for your rest and attention that will make you feel at home.

Superhost
Guest house in Centro
5.0 out of 5 average rating, 3 reviews

Complete centric apartment with garden and pool

Complete centric apartment with an enormous garden and pool. Private apartment with fully staffed kitchen, private bathroom and a bedroom with a queensized bed. You'll also have access to the big garden and the pool to relax and refresh yourself. By choosing our accommodation, you’re also supporting Ñañope, a local NGO dedicated to empowering household workers in Santa Cruz.

Private room in Santa Cruz de la Sierra
4.17 out of 5 average rating, 6 reviews

Cozy little house in the Equipetrol neighborhood

Excellent location, close to entertainment centers, shopping malls, restaurants, cafes, banks, supermarkets, pharmacies, private clinic, oncology hospital and universities. The guest does not need to travel far to find all these amenities in the neighborhood, the apartment is comfortable, independent and has its own garage.

Private room in Centro
4.5 out of 5 average rating, 4 reviews

Double or Full Room in Downtown

New and elegant building located just 2 blocks from the main square, surrounded by shopping malls, restaurants, cafes, jewelry, perfumerias, perfumerias, it is located a couple of blocks from the house of culture, the cathedral, museums, 1 block, banks, 7 street market and various shops and locals.

Private room in Santa Cruz de la Sierra
New place to stay

Just like home

Enjoy the simplicity of this quiet, centrally located place to stay. We are close to Expo Cruz, close to La Ramada, close to the market, Abasto. There are countless restaurants, supermarkets, pharmacies, and clinics. 3rd ring and Pirai.

Guest favourite
Private room in Santa Cruz de la Sierra
4.94 out of 5 average rating, 31 reviews

Apartment in an urban area

Executive private studio apartment, featuring a bedroom, small living room, bar table, kitchen, private bathroom, shared parking, and shared external laundry. It has Cable TV/Wi-Fi, and air conditioning. Located in an urban area.

Guest favourite
A cozy bedroom features a spacious bed dressed in neutral linens, accompanied by decorative cushions. Two wooden chairs are positioned beside a round table near a window with light curtains. A wooden nightstand stands beside the bed, contributing to the room's welcoming atmosphere.
Guest house in Centro
4.88 out of 5 average rating, 135 reviews

Private Apartment In Downtown

Welcome to our cozy guest house in one of the most beautiful and safe areas of the center! Just 6 blocks from Plaza 24 de Septiembre, our historic neighborhood offers you a unique experience.

Guest house in Santa Cruz de la Sierra

Holistic Portal House # 1

Enjoy this mystical space of tranquility and harmony where your nights will be restored and revitalized with the energy of the Holistic Portal

Guest favourite
Private room in Santa Cruz de la Sierra
4.86 out of 5 average rating, 7 reviews

Posada El Peregrino 7

Enjoy the simplicity of this quiet and centrally-located accommodation.

A cozy sleeping area is furnished with a spacious bed adorned with patterned pillows, complemented by a seating area made of wooden pallets. Textured gray walls provide a simple backdrop, while a small table offers additional surface space. Natural light illuminates the room from the doorway.
Guest house in Santa Cruz de la Sierra

Separate room with private bathroom

Relax in this independent accommodation where tranquility is breathed.

Popular amenities for guest house rentals in Santa Cruz de la Sierra