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Holiday rentals in Santa Cruz

Find and book unique accommodation on Airbnb

Top-rated holiday rentals in Santa Cruz

Guests agree: these stays are highly rated for location, cleanliness and more.

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Top guest favourite
A modern dining area features a sleek white table accompanied by two wooden chairs. A cozy bench with soft cushions is positioned against the wall. A large television is mounted nearby, with warm lighting provided by a hanging pendant lamp, creating an inviting space.
Flat in Santa Cruz de la Sierra
5 out of 5 average rating, 24 reviews

"Exclusive apartment with balcony in Equipetrol"

If you are looking for a comfortable and elegant place in Santa Cruz, this apartment is in the heart of Equipetrol and is your best choice. A modern 32 m² studio with a king-size bed, work area, equipped kitchen and fast WiFi, created for you to enjoy every moment of your stay. Relax in an exclusive space with air conditioning and a privileged view from the 12th floor of the building. Here you will experience the perfect balance between rest, style and practicality. Your special experience awaits!

Top guest favourite
An expansive rooftop pool is illuminated by soft lighting, reflecting the city skyline at night. Lounge chairs are neatly arranged along the pool's edge, and the sleek wooden deck complements the modern aesthetic of the space.
Flat in Santa Cruz de la Sierra
4.98 out of 5 average rating, 115 reviews

Luxurious and modern apartment. Equipetrol Sky Elite

This luxurious studio is located in the Equipetrol neighborhood, Sky Elite Building, one block from the Los Tajibos Hotel; it represents the perfect combination of exclusivity and first-class amenities in the city of Santa Cruz de la Sierra, surrounded by restaurants, shops, cafes, pharmacies and supermarkets. The building offers more than 3,000 square meters of social areas including a modern gym, extensive swimming pool, barbecue, coworking, private movie theater, sauna and whirlpool.

Guest favourite
A studio space is presented with a modern aesthetic. A spacious bed is complemented by a sleek couch. The kitchen area features stylish bar stools and dark cabinetry, while a large TV is positioned for easy viewing. Soft lighting enhances the overall ambiance.
Flat in Santa Cruz de la Sierra
4.91 out of 5 average rating, 102 reviews

Cozy & modern · Fully equipped studio

Despertarás en un Studio totalmente equipado que combina comodidad hogareña y confort. Entrarás a un estilo de vida sofisticado; cada detalle ha sido cuidadosamente diseñado para satisfacer altas expectativas. Tendrás todas las comodidades. ¿Relajarse? Sumérgete en la piscina. ¿Ejercicio? ¡Hay Gym! ¿Trabajo? Podrás continuar tu rutina en las múltiples zonas sociales que ofrecen el escenario perfecto.¿Divertirte? Podrás jugar billar y usar la sala común ¡Reserva y descubre este Studio!

Top guest favourite
Serviced apartment in Santa Cruz de la Sierra
5 out of 5 average rating, 35 reviews

Green Tower 26th Floor, Luxury, Panoramic Views

Enjoy your stay in the highest Airbnb in Santa Cruz, and in the best building in the city. In the facilities you can enjoy a swimming pool, steam sauna, spectacular views from the 26th floor towards the beautiful Manzana 40 building, the nature of the ecological cordon and the urubo. A few steps from supermarket, restaurants, mall, business center, banks, spa. The tallest and most beautiful restaurants in Santa Cruz, Cielo Skay Bar and Jardin de Asia, are in the same building.

Top guest favourite
A modern interior is presented, featuring a cozy seating area with a dark sofa, complemented by a circular coffee table. A wooden divider offers separation from the sleeping area, where a spacious bed with neutral bedding is visible. Natural light fills the space from the nearby window.
Flat in Santa Cruz de la Sierra
4.97 out of 5 average rating, 34 reviews

SkyLuxia New Equipetrol Apartment - Safe & Luxurious

Enjoy and relax in this new, quiet and elegant space for two people. Located in Equipetrol, the best area of Santa Cruz, close to restaurants and shopping centers. It offers comfort, convenience and safety. You'll find: WiFi, 55” Smart TV, Cable TV, Air Conditioning, Washer + Dryer. ✔ Large swimming pool and sauna ✔ Gym ✔ Meeting room ✔ 24/7 Reception Fully equipped with towels, shampoo, conditioner, soap, toilet paper, tea, coffee, sugar, salt and oil.

Top guest favourite
A well-appointed living space features a modern kitchen with wooden cabinetry and stainless steel appliances, including a refrigerator. A cozy seating area with a light gray sofa is arranged beside a spacious bed, while natural light filters through large windows.
Flat in Santa Cruz de la Sierra
5 out of 5 average rating, 47 reviews

Smart Studio in Equipetrol

Welcome to this great Smart Apartment in the best residential and business area of Equipetrol. You're half a block from Av. San Martin and a short walk from restaurants, shops, bars, and more. The apartment is fully furnished with everything you need for a comfortable stay, including a fully equipped kitchen, air conditioning, Wi-Fi, and a large flat-screen TV. It has a swimming pool, barbecue, co-work rooms and washing machines on the terrace and common areas

Guest favourite
Flat in Santa Cruz de la Sierra
5 out of 5 average rating, 11 reviews

Spacious studio perfect for you with a desk

Brand-new bright studio in Equipetrol: 5-minute walk to Hotel Los Tajibos and under 100 m from Fidalga Mall. Queen bed, fiber-optic Wi-Fi, full kitchen, balcony and self check-in. Private washer, A/C and smart TV for comfort. Enjoy the rooftop terrace with panoramic pool, gym, barbecue area and coworking space. Minimarkets and cafés within two blocks. Perfect for executives, couples or digital nomads who value style and security. Book now and be amazed!

Top guest favourite
Flat in Santa Cruz de la Sierra
5 out of 5 average rating, 18 reviews

GREEN TOWER SC Luxury Apartment 22nd Floor

Luxury Suite in Green Tower – Santa Cruz 22nd Floor. Live in the tallest and most exclusive building in the city, on the 22nd floor, with panoramic views of Manzana 40, the ecological cordon and the Urubó. Enjoy world-class cuisine in the same building, at Jardines de Asia, Caudilla, and the impressive Sky bar, plus free access to the pool, sauna, steakhouse and Sport Motion gym. A new apartment! Furnished with high-end pieces, including a large sofa bed.

Top guest favourite
A spacious bed is positioned against a large window, offering a view of the cityscape. Soft pillows and a neatly arranged blanket enhance the comfort of the sleeping area. A small rug lies on the floor, complementing the modern decor.
Flat in Santa Cruz de la Sierra
4.88 out of 5 average rating, 134 reviews

Comfortable/modern studio apartment beautiful view 300Mbps

Bienvenidos a la zona más activa de Santa Cruz! El precio ya incluye todas las comisiones no pagarás nada adicional en la app. El apartamento es un monoambiente totalmente equipado, moderno y cómodo. Cuenta con una cama de 2 plazas y un sofá cama además del baño privado, lavadora/secadora, cocina y todos los electrodomésticos necesarios. Internet Wi-Fi, tv cable y NETFLIX. Cerca de supermercados, los mejores restaurantes de la ciudad y malls.

Top guest favourite
A comfortable sleeping area features a spacious bed adorned with soft pillows and a decorative throw. Warm bedside lamps illuminate the space, while large windows offer views of the surrounding cityscape and allow natural light to brighten the room.
Flat in Santa Cruz de la Sierra
4.98 out of 5 average rating, 121 reviews

13° SmartLife - Luxury Equipetrol

Welcome to your sanctuary of sophistication and elegance at the top. This exceptionally cozy and stylish studio on the 13th floor invites you to experience luxury and comfort at their finest. Ready to experience the perfect combination of sophistication, comfort, and technology? Don't miss out on this unique opportunity. Book your stay at "13° SmartLife" and be seduced by the charm of this incomparable space! Your urban retreat awaits.

Guest favourite
Flat in Santa Cruz de la Sierra
4.89 out of 5 average rating, 123 reviews

Beautiful 1-bedroom apartment

One-bedroom apartment, perfect for your next stay in Santa Cruz de la Sierra! Centrally located a few steps from Equipetrol, the city's commercial, business and social center. The unit has a cozy space that offers all the necessary amenities for a comfortable and memorable stay. It includes a service area, washer and dryer, iron, coffee maker, dishes, bed linens, 2 55” smart TVs with cable, Netflix, and a sofa bed. Reserve now!

Top guest favourite
Flat in Santa Cruz de la Sierra
5 out of 5 average rating, 13 reviews

POX: 24th Floor Green Tower | Luxury and Panoramic View

Hi, we're POX! We'll make sure you have an unforgettable stay. Experience staying on the 24th floor of the iconic Green Tower, the most exclusive and luxurious building in the country. Enjoy a breathtaking view from a modern, bright and fully equipped space. Ideal for business travelers, couples, or extended stays in style. Get ready for the Green Tower experience! POX, rest, enjoy, repeat.

Popular amenities for Santa Cruz holiday rentals

  1. Airbnb
  2. Bolivia
  3. Santa Cruz