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Holiday rentals in Santa Cruz

Find and book unique accommodation on Airbnb

Top-rated holiday rentals in Santa Cruz

Guests agree: these stays are highly rated for location, cleanliness and more.

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Top guest favourite
The living area features a comfortable couch positioned near a large window, allowing natural light to fill the space. A flat-screen television is mounted on a wood-paneled wall, and a small round table is visible nearby. The view showcases the city skyline and nearby greenery.
Apartment in Santa Cruz de la Sierra
5 out of 5 average rating, 28 reviews

Luxury, comfort, ideal location

Bienvenidos a la mejor ubicación de Santa Cruz! En el corazón del centro empresarial, pero en una calle tranquila. Supermercados y mucho más a la vuelta de la esquina. A pocos pasos encontrarás decenas de restaurantes increíbles: parrillada, comida japonesa, italiana o americana. Comida rápida o cenas elegantes. Manzana 40 está a 10 minutos a pie. Ventura Mall está a solo 5 min en auto. Ya sea para trabajo o diversión, este es el lugar ideal! El edificio cuenta con personal de seguridad 24/7.

Top guest favourite
An expansive rooftop pool is illuminated by soft lighting, reflecting the city skyline at night. Lounge chairs are neatly arranged along the pool's edge, and the sleek wooden deck complements the modern aesthetic of the space.
Flat in Santa Cruz de la Sierra
4.98 out of 5 average rating, 134 reviews

Luxurious and modern apartment. Equipetrol Sky Elite

This luxurious studio is located in the Equipetrol neighborhood, Sky Elite Building, one block from the Los Tajibos Hotel; it represents the perfect combination of exclusivity and first-class amenities in the city of Santa Cruz de la Sierra, surrounded by restaurants, shops, cafes, pharmacies and supermarkets. The building offers more than 3,000 square meters of social areas including a modern gym, extensive swimming pool, barbecue, coworking, private movie theater, sauna and whirlpool.

Guest favourite
A modern studio design features a spacious bed complemented by a geometric shelving unit. Natural light enters through large windows, illuminating the warm wood accents. A dining area with colorful chairs and a work desk is visible in the background, enhancing the multifunctional layout.
Flat in Santa Cruz de la Sierra
4.87 out of 5 average rating, 154 reviews

25% off NOW! Don't pay more than you have to.

Preparado para estar en la mejor zona de Santa Cruz? Este Studio es moderno con una vista hermosa de la ciudad, además de tener excelentes zonas de diversión como piscina, mesa de billar e incluso su propio Beer Garden. Si lo que buscas es trabajar cuentas con una zona co-work y sala de reuniones. Si te gustaría conocer el vecindario, hay comercio y varias opciones gastronómicas en los alrededores. Si tienes hijos o tu amigo peludo, cruzando la calle cuentas con un pequeño parque.

Guest favourite
Flat in Santa Cruz de la Sierra
4.93 out of 5 average rating, 27 reviews

Smart apartment with pool and views of SCZ Equipetrol

Cozy new apartment located in the best area of Santa Cruz, in the heart of Equipetrol, the city's gastronomic and commercial center, just steps away from the best restaurants and shopping centers. Home automation, lighting control, climate control, Wi-Fi, Smart TV and cable. New Technological, Modern Building with Amenities that will make your experience unforgettable. It has an infinity pool on the roof with views of the entire city, sauna, co-working, game room and steakhouses.

Top guest favourite
Serviced apartment in Santa Cruz de la Sierra
5 out of 5 average rating, 45 reviews

Green Tower 26th Floor, Luxury, Panoramic Views

Enjoy your stay in the highest Airbnb in Santa Cruz, and in the best building in the city. In the facilities you can enjoy a swimming pool, steam sauna, spectacular views from the 26th floor towards the beautiful Manzana 40 building, the nature of the ecological cordon and the urubo. A few steps from supermarket, restaurants, mall, business center, banks, spa. The tallest and most beautiful restaurants in Santa Cruz, Cielo Skay Bar and Jardin de Asia, are in the same building.

Top guest favourite
A contemporary entryway featuring sleek, metallic walls and smooth marble flooring. A minimalist reception desk with soft ambient lighting displays the name 'NUU.' A large potted plant adds a touch of greenery, while well-placed lighting creates a bright atmosphere.
Flat in Santa Cruz de la Sierra
4.95 out of 5 average rating, 61 reviews

apartment with an excellent view

Apartment located in the Equipetrol area. Located on the 13th floor, you'll enjoy stunning views in a comfortable and elegant atmosphere. This apartment has two bedrooms and two bathrooms, ideal for families or groups. It's fully equipped to make you feel at home. Among the building's amenities, you will find a cinema, a swimming pool, a barbecue area, an equipped gym, a playground, and parking for visitors. Easy access to restaurants, shops, and attractions.

Top guest favourite
A well-appointed living space features a modern kitchen with wooden cabinetry and stainless steel appliances, including a refrigerator. A cozy seating area with a light gray sofa is arranged beside a spacious bed, while natural light filters through large windows.
Flat in Santa Cruz de la Sierra
5 out of 5 average rating, 51 reviews

Smart Studio in Equipetrol

Welcome to this great Smart Apartment in the best residential and business area of Equipetrol. You're half a block from Av. San Martin and a short walk from restaurants, shops, bars, and more. The apartment is fully furnished with everything you need for a comfortable stay, including a fully equipped kitchen, air conditioning, Wi-Fi, and a large flat-screen TV. It has a swimming pool, barbecue, co-work rooms and washing machines on the terrace and common areas

Top guest favourite
A modern living area is presented, featuring a comfortable gray sofa facing a large window with city views. A sleek, wall-mounted television is positioned above a stylish wooden console. Natural light fills the room, complemented by decorative plants and minimalist artwork.
Flat in Santa Cruz de la Sierra
5 out of 5 average rating, 39 reviews

Xquisite Suite - 1 Room Equipetrol North

Discover elegance in this cozy 1-bedroom apartment with dreamy views. Experience the luxury of extreme equipment with a 65" 4K HDR Smart TV in the living room and another 50" TV in the bedroom, powerful air conditioning equipment, a washing machine, and necessary appliances, an Ultra Comfort Queen bed, a changing table and a dresser, as well as home automation and Alexa to fulfill your orders. Experience the synthesis of modernity like never before, book NOW!

Superhost
Flat in Santa Cruz de la Sierra
5 out of 5 average rating, 4 reviews

Balcony - View - Work Area - Pool - Gym

A metros del 2do anillo, zona Equipetrol, muchos restaurantes, tiendas, supermercados, gimnasios entre otros. Con balcón y una vista del piso 14, piscina, sauna, área de trabajo, gimnasio y otros en las áreas sociales. Departamento con: - Sofa cama - Cocina - Lavadora - Smart TV - Baño equipado - Living - Dormitorio - WiFi 100 Mb En el edificio contarás con: - Piscina - Gimnasio - Área de trabajo - Área de juegos Vive la experiencia y reserva ya!

Guest favourite
A tranquil studio space features a spacious bed dressed with light linens and decorative pillows. A cozy seating area includes a dark grey sofa and a round wooden coffee table. Natural light streams through a large window draped with light curtains, highlighting a wall accentuated with soft textures.
Apartment in Santa Cruz de la Sierra
4.87 out of 5 average rating, 269 reviews

Quiet Monoenvironment in Equipetrol

Enjoy the simplicity of this quiet studio in the heart of Equipetrol, where you can be close to restaurants, supermarkets, squares, churches, the business center if you come for work in the same way. In your leisure time, the studio has Wify, TV, Netflix, kitchen, microwave, oven, refrigerator and everything you need to be comfortable inside the building, since in the social areas you can enjoy the pool, churrasqueras, game room and coWork

Guest favourite
Flat in Santa Cruz de la Sierra
5 out of 5 average rating, 13 reviews

POX: Green Tower 16th floor | Luxury and elegance - 2H

Live the POX experience! We present our largest apartment in the iconic Green Tower, the most exclusive and luxurious building in Santa Cruz. A fully equipped apartment for you to live a unique experience with your family or friends. Be dazzled by the best view of the city, 24/7 service and close to banks, restaurants, shopping malls, everything you need meters away. We'll make sure you have a great stay, welcome to POX!

Top guest favourite
Flat in Santa Cruz de la Sierra
5 out of 5 average rating, 28 reviews

Casa Zen – Comfort Getaway (Barrio Equipetrol)

Modern, peaceful, and perfectly located — Casa Zen is your comfort getaway in the heart of Equipetrol. Just steps from the lively Av. San Martín, surrounded by top restaurants, cafés, and city life. This space was thoughtfully designed to offer you peace and comfort. Enjoy luxury amenities including a pool, sauna, gym, and more — everything you need to unwind, recharge, and feel truly at home from the moment you arrive.

Popular amenities for Santa Cruz holiday rentals

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