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Holiday rentals in Santa Cruz

Find and book unique accommodation on Airbnb

Top-rated holiday rentals in Santa Cruz

Guests agree: these stays are highly rated for location, cleanliness and more.

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Top guest favourite
A modern living space featuring large floor-to-ceiling windows that provide a bright view of the cityscape. A comfortable sofa and a table are positioned in front of a TV mounted on a wooden panel. The kitchen area is equipped with stylish appliances and an island.
Flat in Santa Cruz de la Sierra
5 out of 5 average rating, 29 reviews

Classic Executive Studio

12 FLOOR! Auto Check-in, Aire Acondicionado, Lavadora, Cocina, Sofa y TV perfecto para trabajar todo el día con una vista verde de un 12 piso desde el barrio más cotizado de la ciudad, Equipetrol. Si te aburres puedes usar la piscina sin costo, áreas sociales, asado BBQ. Si te aburres más estarás a 2 minutos de Supermercados, Farmacias a cuadras de la principal de Equipetrol con Restaurantes renombrados, a 5 min de la Plaza Central o a 5 min del shopping más grande de Bolivia, Ventura Mall.

Top guest favourite
An expansive rooftop pool is illuminated by soft lighting, reflecting the city skyline at night. Lounge chairs are neatly arranged along the pool's edge, and the sleek wooden deck complements the modern aesthetic of the space.
Flat in Santa Cruz de la Sierra
4.99 out of 5 average rating, 101 reviews

Luxurious and modern apartment. Equipetrol Sky Elite

This luxurious monoenvironment is located in the Barrio Equipetrol, Edificio Sky Elite, one block from Hotel Los Tajibos; it represents the perfect combination of exclusivity and world-class amenities in the city of Santa Cruz de la Sierra, surrounded by restaurants, shops, cafes, pharmacies and supermarkets. The building offers over 3,000 square meters of social areas including a modern gym, extensive pool, churrasquera, cowork, private movie theater, sauna and whirlpool.

Top guest favourite
Green Tower, one of the tallest buildings in Bolivia, showcases modern architecture with its glass facade reflecting the surrounding cityscape. The image captures the building's contemporary design, set against a backdrop of Santa Cruz, featuring both urban and natural elements.
Serviced apartment in Santa Cruz de la Sierra
5 out of 5 average rating, 30 reviews

Piso 26 Green Tower-Vistas Espectaculares

Enjoy your stay in the tallest airbnb in Santa Cruz, and in the best building in the city, in the facilities you can enjoy Piscina, Sauna a Vapor, spectacular views from the 26th floor towards the beautiful Manzana 40 building, the nature of the ecological cordon and the urubo. A few steps from supermarket, restaurants, mall, business center, banks, spa. In the building There are the tallest and most beautiful restaurants in Santa Cruz , Cielo skay bar and Jardin in Asia.

Top guest favourite
Flat in Santa Cruz de la Sierra
5 out of 5 average rating, 12 reviews

GREEN TOWER SC Luxury Apartment 22nd Floor

Luxury suite in Green Tower – Santa Cruz 22nd Floor. Live in the tallest and most exclusive building in the city, on the 22nd floor, with panoramic views of Manzana 40, the ecological cordon and the Urubó. Enjoy world-class cuisine in the same building, at Jardines de Asia, Caudilla, and the impressive Sky bar, as well as free access to the pool, sauna, barbecues and the Sport Motion gym. A new apartment! Furnished with high-end pieces, including a large sofa bed.

Guest favourite
A studio space is presented with a modern aesthetic. A spacious bed is complemented by a sleek couch. The kitchen area features stylish bar stools and dark cabinetry, while a large TV is positioned for easy viewing. Soft lighting enhances the overall ambiance.
Flat in Santa Cruz de la Sierra
4.92 out of 5 average rating, 98 reviews

Experience luxury and comfort

You'll wake up in a fully-equipped studio that combines home comfort and hotel opulence. You'll enter a sophisticated lifestyle; every detail has been carefully designed to meet high expectations. You'll have all the amenities. Relax? Dive into the pool. Exercise? There's a gym! Work? You can continue your routine in the multiple social areas that offer the perfect setting.Have fun? You can play pool and use the common room. Book and discover this Studio!

Guest favourite
A modern living area features a comfortable sofa adorned with decorative pillows, alongside a sleek TV unit. Large windows offer panoramic city views, while two round mirrors enhance the brightness of the space. A small chair and indoor plant add a touch of decor.
Flat in Santa Cruz de la Sierra
4.98 out of 5 average rating, 48 reviews

Modern Apt WiFi, AC, Kitchen, Pool, Washer, Parkng

✨ A space designed for your comfort and relaxation. Located in a safe and quiet area, this modern apartment combines style, convenience, and technology to offer you a unique experience. Perfect for business travelers, couples, or small families, this accommodation features high-speed WiFi, air conditioning, and premium entertainment, along with access to a pool, gym, and free parking. 📌 Enjoy an unforgettable stay with all the amenities you deserve!

Top guest favourite
An outdoor terrace features sleek wooden decking, complemented by low seating arrangements and lush greenery. A tranquil water feature runs along one side, reflecting the surrounding cityscape. Modern buildings rise in the background under a clear, blue sky.
Flat in Santa Cruz de la Sierra
4.97 out of 5 average rating, 39 reviews

Elegante departamento familiar en Equipetrol

Have fun with the family in this new, central, and stylish accommodation. Beautiful and modern apartment located in the best area of Santa Cruz. Just a few steps away from the city's best restaurants, pharmacies, supermarkets, cafes, nightclubs, and shopping malls. Ideal for families, a group of friends, or two couples. You can have all the comforts of a luxury apartment for a cozy and pleasant stay. The building's common areas are a dream!

Top guest favourite
A spacious bed is positioned against a large window, offering a view of the cityscape. Soft pillows and a neatly arranged blanket enhance the comfort of the sleeping area. A small rug lies on the floor, complementing the modern decor.
Flat in Santa Cruz de la Sierra
4.88 out of 5 average rating, 128 reviews

Comfortable/modern studio with beautiful view 300Mbps

Bienvenidos a la zona más activa de Santa Cruz! El precio ya incluye todas las comisiones no pagarás nada adicional en la app. El apartamento es un monoambiente totalmente equipado, moderno y cómodo. Cuenta con una cama de 2 plazas y un sofá cama además del baño privado, lavadora/secadora, cocina y todos los electrodomésticos necesarios. Internet Wi-Fi, tv cable y NETFLIX. Cerca de supermercados, los mejores restaurantes de la ciudad y malls.

Guest favourite
A cozy sleeping area features a spacious bed adorned with patterned bedding and two decorative pillows. A vibrant painting depicting a colorful street scene hangs above the headboard, complemented by wooden wall panels and a small shelf displaying decor.
Loft in Santa Cruz de la Sierra
4.94 out of 5 average rating, 199 reviews

Equipetrol: Luxury studio superking bed & Restobar

Magnificent apartment located in a privileged area of ​​the city, furnished and equipped with the essentials for a pleasant stay. The studio has a super king size bed, living-dining room, large kitchen, closet, balcony with unbeatable view of the city and private bathroom. Access to swimming pool, Resto-Bar, co-work room, entertainment room, pool table, barbecue and outdoor environments with a beautiful view of Equipetrol all on the 7th floor.

Guest favourite
A tranquil studio space features a spacious bed dressed with light linens and decorative pillows. A cozy seating area includes a dark grey sofa and a round wooden coffee table. Natural light streams through a large window draped with light curtains, highlighting a wall accentuated with soft textures.
Apartment in Santa Cruz de la Sierra
4.88 out of 5 average rating, 236 reviews

Quiet Monoenvironment in Equipetrol

Enjoy the simplicity of this quiet studio in the heart of Equipetrol, where you can be close to restaurants, supermarkets, squares, churches, the business center if you come for work in the same way. In your leisure time, the studio has Wify, TV, Netflix, kitchen, microwave, oven, refrigerator and everything you need to be comfortable inside the building, since in the social areas you can enjoy the pool, churrasqueras, game room and coWork

Guest favourite
A comfortable sleeping area features a spacious bed adorned with soft pillows and a decorative throw. Warm bedside lamps illuminate the space, while large windows offer views of the surrounding cityscape and allow natural light to brighten the room.
Flat in Santa Cruz de la Sierra
4.97 out of 5 average rating, 115 reviews

13° SmartLife - Luxury Equipetrol

Welcome to your sanctuary of sophistication and elegance at the top. This exceptionally cozy and stylish studio on the 13th floor invites you to experience luxury and comfort at their finest. Ready to experience the perfect combination of sophistication, comfort, and technology? Don't miss out on this unique opportunity. Book your stay at "13° SmartLife" and be seduced by the charm of this incomparable space! Your urban retreat awaits.

Guest favourite
A modern bedroom features a spacious bed with light-colored bedding and decorative pillows. Wooden paneling creates a warm aesthetic, complemented by wall-mounted plants. Natural light enters through floor-to-ceiling windows, and a small bedside lamp offers a soft glow.
Apartment in Santa Cruz de la Sierra
4.93 out of 5 average rating, 121 reviews

Modern Studio with a beautiful view in Equipetrol

We offer you a comfortable stady with everything you may need, in this modern and new place with our top quality service. This place is fully furnished and has a beautiful view. Is located in the best area from Santa Cruz, and also near of fancy restaurants, malls and business area. You can have access to building's social areas like: co-work zone, pool, steakhouse and laundry. (pics)

Popular amenities for Santa Cruz holiday rentals

  1. Airbnb
  2. Bolivia
  3. Santa Cruz