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Holiday rentals in Santa Cruz

Find and book unique accommodation on Airbnb

Top-rated holiday rentals in Santa Cruz

Guests agree: these stays are highly rated for location, cleanliness and more.

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Top guest favourite
The living area features a comfortable couch positioned near a large window, allowing natural light to fill the space. A flat-screen television is mounted on a wood-paneled wall, and a small round table is visible nearby. The view showcases the city skyline and nearby greenery.
Apartment in Santa Cruz de la Sierra
5 out of 5 average rating, 25 reviews

Luxury, comfort, ideal location

Bienvenidos a la mejor ubicación de Santa Cruz! En el corazón del centro empresarial, pero en una calle tranquila. Supermercados y mucho más a la vuelta de la esquina. A pocos pasos encontrarás decenas de restaurantes increíbles: parrillada, comida japonesa, italiana o americana. Comida rápida o cenas elegantes. Manzana 40 está a 10 minutos a pie. Ventura Mall está a solo 5 min en auto. Ya sea para trabajo o diversión, este es el lugar ideal! El edificio cuenta con personal de seguridad 24/7.

Top guest favourite
Flat in Santa Cruz de la Sierra
5 out of 5 average rating, 20 reviews

GREEN TOWER SC Luxury Apartment 22nd Floor

Suite de lujo en Green Tower – Santa Cruz Piso 22. Vive en el edificio más alto y exclusivo de la ciudad, en el piso 22, con vistas panorámicas a Manzana 40, el cordón ecológico y el Urubó. Disfruta de gastronomía de primer nivel en el mismo edificio, en Jardines de Asia, Caudilla, Palosanto y el impresionante Sky bar, además acceso libre a la piscina, sauna, churrasqueras. Cuenta con gimnasio Sport Motion. Un departamento nuevo! amoblado con piezas de alta gama, incluyendo sofá cama grande.

Top guest favourite
An expansive rooftop pool is illuminated by soft lighting, reflecting the city skyline at night. Lounge chairs are neatly arranged along the pool's edge, and the sleek wooden deck complements the modern aesthetic of the space.
Flat in Santa Cruz de la Sierra
4.98 out of 5 average rating, 117 reviews

Luxurious and modern apartment. Equipetrol Sky Elite

This luxurious studio is located in the Equipetrol neighborhood, Sky Elite Building, one block from the Los Tajibos Hotel; it represents the perfect combination of exclusivity and first-class amenities in the city of Santa Cruz de la Sierra, surrounded by restaurants, shops, cafes, pharmacies and supermarkets. The building offers more than 3,000 square meters of social areas including a modern gym, extensive swimming pool, barbecue, coworking, private movie theater, sauna and whirlpool.

Top guest favourite
An inviting pool area is surrounded by modern buildings, featuring lounge chairs arranged neatly along the water's edge. The pool's surface reflects the colorful lights of the surrounding structures and the evening sky, creating a tranquil atmosphere.
Serviced apartment in Santa Cruz de la Sierra
5 out of 5 average rating, 37 reviews

Green Tower 26th Floor, Luxury, Panoramic Views

Enjoy your stay in the highest Airbnb in Santa Cruz, and in the best building in the city. In the facilities you can enjoy a swimming pool, steam sauna, spectacular views from the 26th floor towards the beautiful Manzana 40 building, the nature of the ecological cordon and the urubo. A few steps from supermarket, restaurants, mall, business center, banks, spa. The tallest and most beautiful restaurants in Santa Cruz, Cielo Skay Bar and Jardin de Asia, are in the same building.

Guest favourite
A rooftop pool reflects city lights against the night sky, creating a serene atmosphere. The pool area features a sleek design with modern lighting and a shower head. The distant skyline of Santa Cruz adds to the captivating view, enhancing the overall experience.
Apartment in Santa Cruz de la Sierra
4.9 out of 5 average rating, 136 reviews

Magnificent Apartment Exclusive Area Equipetrol

Spectacular apartment in the most privileged area of Santa Cruz. In addition to having shops, luxury restaurants, and shopping centers nearby. Bicycles and Electric Scooters with the Mobi App. Fully furnished apartment equipped with the essentials for a pleasant stay. Access to a swimming pool overlooking the city, co-work, conference room, entertainment room, poker table, barbecues, and outdoor areas with a beautiful view of Equipetrol, all on the 8th floor.

Top guest favourite
A well-appointed living space features a modern kitchen with wooden cabinetry and stainless steel appliances, including a refrigerator. A cozy seating area with a light gray sofa is arranged beside a spacious bed, while natural light filters through large windows.
Flat in Santa Cruz de la Sierra
5 out of 5 average rating, 48 reviews

Smart Studio in Equipetrol

Welcome to this great Smart Apartment in the best residential and business area of Equipetrol. You're half a block from Av. San Martin and a short walk from restaurants, shops, bars, and more. The apartment is fully furnished with everything you need for a comfortable stay, including a fully equipped kitchen, air conditioning, Wi-Fi, and a large flat-screen TV. It has a swimming pool, barbecue, co-work rooms and washing machines on the terrace and common areas

Guest favourite
Flat in Santa Cruz de la Sierra
5 out of 5 average rating, 12 reviews

Spacious studio perfect for you with a desk

Brand-new bright studio in Equipetrol: 5-minute walk to Hotel Los Tajibos and under 100 m from Fidalga Mall. Queen bed, fiber-optic Wi-Fi, full kitchen, balcony and self check-in. Private washer, A/C and smart TV for comfort. Enjoy the rooftop terrace with panoramic pool, gym, barbecue area and coworking space. Minimarkets and cafés within two blocks. Perfect for executives, couples or digital nomads who value style and security. Book now and be amazed!

Guest favourite
An outdoor terrace features sleek wooden decking, complemented by low seating arrangements and lush greenery. A tranquil water feature runs along one side, reflecting the surrounding cityscape. Modern buildings rise in the background under a clear, blue sky.
Flat in Santa Cruz de la Sierra
4.96 out of 5 average rating, 47 reviews

Elegant family apartment in Equipetrol

Have fun with the family in this new, central, and stylish accommodation. Beautiful and modern apartment located in the best area of Santa Cruz. Just a few steps away from the city's best restaurants, pharmacies, supermarkets, cafes, nightclubs, and shopping malls. Ideal for families, a group of friends, or two couples. You can have all the comforts of a luxury apartment for a cozy and pleasant stay. The building's common areas are a dream!

Top guest favourite
Flat in Santa Cruz de la Sierra
4.88 out of 5 average rating, 135 reviews

Comfortable/modern studio apartment beautiful view 300Mbps

Bienvenidos a la zona más activa de Santa Cruz! El precio ya incluye todas las comisiones no pagarás nada adicional en la app. El apartamento es un monoambiente totalmente equipado, moderno y cómodo. Cuenta con una cama de 2 plazas y un sofá cama además del baño privado, lavadora/secadora, cocina y todos los electrodomésticos necesarios. Internet Wi-Fi, tv cable y NETFLIX. Cerca de supermercados, los mejores restaurantes de la ciudad y malls.

Guest favourite
A comfortable sleeping area features a spacious bed adorned with soft pillows and a decorative throw. Warm bedside lamps illuminate the space, while large windows offer views of the surrounding cityscape and allow natural light to brighten the room.
Flat in Santa Cruz de la Sierra
4.98 out of 5 average rating, 123 reviews

13° SmartLife - Luxury Equipetrol

Welcome to your sanctuary of sophistication and elegance at the top. This exceptionally cozy and stylish studio on the 13th floor invites you to experience luxury and comfort at their finest. Ready to experience the perfect combination of sophistication, comfort, and technology? Don't miss out on this unique opportunity. Book your stay at "13° SmartLife" and be seduced by the charm of this incomparable space! Your urban retreat awaits.

Guest favourite
Flat in Santa Cruz de la Sierra
5 out of 5 average rating, 13 reviews

Equipetrol Luxury Studio with Balcony and Style

Experience luxury and comfort in the heart of Equipetro! Welcome to Sky Luxia, where design and functionality merge to offer you a unique experience. This elegant studio with balcony has been designed for your comfort and lifestyle. Enjoy the exclusive amenities: panoramic pool, gym, lounge, sauna, game room and barbecue grills, all with 24-hour security. The best restaurants, cafes, and entertainment venues are just steps away.

Top guest favourite
An outdoor swimming pool is set against a skyline backdrop, featuring clear water and a sleek dark stone structure nearby. Two lounge chairs are positioned beside the pool, offering a space for relaxation while enjoying the view of the city.
Flat in Santa Cruz de la Sierra
5 out of 5 average rating, 16 reviews

New & Equipped Studio | Prime Location

Brand-new, fully equipped studio in an unbeatable location. Perfect for both work and relaxation. Enjoy fast WiFi, an integrated kitchen, and a modern space designed for your comfort. Situated in the city’s best area, close to restaurants, cafés, and top attractions. You’ll also have access to the condominium pool. Ideal for guests seeking comfort, convenience, and a cozy atmosphere, with 24/7 security and a peaceful environment.

Popular amenities for Santa Cruz holiday rentals

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