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Apartment holiday rentals in Santa Cruz de la Sierra

Find and book unique apartments on Airbnb

Top-rated apartment rentals in Santa Cruz de la Sierra

Guests agree: these apartments are highly rated for location, cleanliness and more.

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Top guest favourite
A bright room features a spacious bed with light bedding against an arched wall. A small table holds a bowl of oranges. Open windows provide views of the outdoors, complementing the soothing ambiance created by warm lighting.
Flat in Cáceres
4.94 out of 5 average rating, 108 reviews

Apartments Plaza Mayor 35, 204 Studio Plaza

Apartamentos Plaza Mayor 35 is the ideal option for travelers interested in getting to know the Monumental Complex of Cáceres. We offer 11 unique apartments located in the Plaza Mayor de Cáceres, two steps from one of the most complete urban complexes of the Middle Ages in the world.The apartments are located in acozy manor house completely renovated with free Wi-Fi, air conditioning hot/cold, fully equipped kitchen, large living room with sofa bed, comfortable rooms and bathroom with shower.

Guest favourite
A cozy kitchen area features exposed brick walls and a modern layout. Stainless steel appliances include a washing machine and a stove. A small round table is set for two, complemented by a balcony access door, allowing natural light into the space.
Flat in Cáceres
4.92 out of 5 average rating, 329 reviews

Unbeatable location in Historic Center ATCC00523

The apartment is located in the heart of the Historic Center, declared a World Heritage Site, less than 100 meters from the Plaza Mayor and surrounded by the city's main monuments. In this Monumental Zone you can enjoy important free and outdoor musical events such as Womad, Irish Fleadh, Blues Festival etc. As well as a theater festival and a medieval market. Less than a 5-minute walk away are cafes, restaurants, shops, and public transportation. LIC-AT-CC-00523

Top guest favourite
A private terrace is depicted, featuring a dark glass table reflecting the sunlight. Two potted plants are positioned at opposite ends, with one chair placed next to the table. The clear blue sky is visible above, enhancing the serene atmosphere.
Flat in Cáceres
4.99 out of 5 average rating, 83 reviews

Macarena Suites "A" with private parking and terrace

¡Descubre Macarena Suites, tu refugio de lujo estrenado este 2025 en el corazón de la Ciudad Monumental! Disfruta de apartamentos exclusivos con terraza privada y acceso sin escaleras. Destacamos por nuestra comodidad inigualable: parking privado en el mismo edificio, cerraduras inteligentes para llegada autónoma y equipamiento premium con cocina completa. Vive el silencio y el encanto histórico con el máximo confort moderno. ¡Reserva tu experiencia única!

Top guest favourite
A spacious living and dining area features modern furniture and an artistic wall mural. A dining table is paired with several black chairs, while a comfortable seating arrangement includes a couch and a television. Natural light is allowed through window openings with wooden shutters.
Flat in Cáceres
4.99 out of 5 average rating, 147 reviews

Gran Apartamento Turistico Sir Galahad

Spacious and accessible accommodation, cozy, great views towards the Plaza Mayor and Old Town with all the necessary amenities for your comfort. Views towards the Wall, Arco de la Estrella, City Hall, a few meters away you can find Restaurants, Pharmacy, Pedestrian street of shops, Banks and Taxi Stop. Our apartment is located in the Monumental Zone. With prior authorization that we manage, it can be accessed for loading and unloading of luggage.

Superhost
A spacious living area features a comfortable sofa and an elegant coffee table. Large windows open to a view of the plaza, allowing natural light to flood in. A decorative wall art piece adds color to the neutral-toned walls, complemented by a compact dining table.
Flat in Cáceres
4.72 out of 5 average rating, 170 reviews

Plaza Mayor Cáceres Apartment

Beautiful apartment in the main square of Cáceres, has unique views of the historic city, a world heritage site, history is breathed, the apartment has an unbeatable location to enjoy the city and make tourist, gastronomic routes. At the same time the house is spacious and very quiet and comfortable to have an unforgettable stay. The house has been renovated in November 2018 and is fully equipped, so you can feel at home

Top guest favourite
A modern living space features a pink sofa centered in the room, complemented by a glass coffee table. Below, a transparent floor reveals illuminated ancient Roman ruins. A dining table with chairs is positioned in the corner, and soft natural light filters through sheer curtains.
Flat in Mérida
4.97 out of 5 average rating, 116 reviews

Proserpina- Central apartment with Roman ruins

Stay in a unique place! CMDreams are 4 tourist apartments located in the center of Merida, with private and covered parking. If something differentiates us, it is having preserved history to share it with our guests. You can walk on a glass floor and enjoy the Roman ruins that are visible and illuminated below. If you are looking for an unforgettable experience with the highest quality, book Apartamentos CMDreams.

Guest favourite
A wide-open landscape is depicted with rolling hills and patches of lush greenery. A large tree stands on the right, while distant mountains are visible under a cloudy sky. The scene conveys a serene and natural setting, ideal for nature lovers.
Flat in Cabañas del Castillo
4.93 out of 5 average rating, 113 reviews

Charming studio with views

Studio apartment that was once an attic and now welcomes you as if it were a nest. It's small and simple but with handmade and original details that make it different. It's an ideal place for those looking to relax, for nature lovers and trails to walk quietly, without crowds. And it's especially a good place for birdwatching and the night sky.

Top guest favourite
A bright studio apartment is featured, showcasing a minimalist kitchen with a sink, stove, and storage drawers. A sofa bed is positioned across from a dining table with two chairs, offering a practical living space. Natural light fills the room through the window.
Flat in Mérida
4.96 out of 5 average rating, 166 reviews

Cozy Centrally-Located Studio 2

Enjoy the simplicity of this quiet, bright, cozy and centrally located place. Come and feel at home, as if it were your own home! This studio is offered so that you can enjoy your stay in Mérida whether it is your first time in these charming lands or if you already know its charms.

Guest favourite
A cozy bedroom features floral wallpaper with soft hues and a white metal bed adorned with a patterned blanket and yellow accent pillows. A white dressing table and mirror are positioned beside a window, letting in natural light, complemented by soft bedside lamps.
Flat in Campo Lugar
5 out of 5 average rating, 25 reviews

Rural Charm and Comfort, Casa Rural de la Vega 2

Welcome to Apartamentos de La Vega, a cozy family-run rural retreat, located in the picturesque village of Campo Lugar. These spacious, rustic-style apartments have been carefully decorated with charming details that will transport you to the area's natural beauty.

Guest favourite
A modern living area is presented with light wooden flooring and large windows allowing natural light. The space features a gray sofa, two accent chairs, and a round coffee table. A dining table with white chairs is positioned to enhance the functionality of the room.
Flat in Trujillo
4.93 out of 5 average rating, 14 reviews

La Pata Suites. Apartment 2

Enjoy a luxury experience in this centrally located accommodation, located 10 meters from Plaza Mayor. Opened in April 2025 after a comprehensive renovation. Personal information will be required from guests in accordance with current legislation.

Guest favourite
A modern studio layout features a cozy seating area with a gray sofa adorned with striped cushions. A dining table sits adjacent to a kitchen space, complemented by a decorative bowl of fruit. Natural light flows in through a window framed by light curtains, enhancing the space.
Flat in Mérida
4.87 out of 5 average rating, 130 reviews

AP1- Modern studio in Plaza de la Constitución

Enjoy a luxurious experience in this modern one-room studio located in one of the most charming squares in Mérida where you can enjoy everything the city has to offer and with all the amenities.

Superhost
Flat in Conquista de la Sierra
4.88 out of 5 average rating, 33 reviews

Balcony of the Sierra- The holm oak

In this accommodation, where old construction is mixed with modern decoration, stonework and coffered ceilings come together in a single perspective.

Popular amenities for Santa Cruz de la Sierra apartment rentals

  1. Airbnb
  2. Spain
  3. Extremadura
  4. Cáceres
  5. Santa Cruz de la Sierra
  6. Flat rentals