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Holiday rentals in Santa Cruz

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Top-rated holiday rentals in Santa Cruz

Guests agree: these stays are highly rated for location, cleanliness and more.

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Top guest favourite
A cozy living space features dark walls adorned with colorful artwork. Comfortable seating includes a sofa and two lounge chairs, positioned around a small table. Natural light filters through large windows, illuminating the room and highlighting wooden flooring.
Flat in Santa María La Ribera
4.91 out of 5 average rating, 563 reviews

Independent apartment on 3 levels and 2 bathrooms.

New apartment on three levels with splendid views of a beautiful Mexican-Andalusian garden. Two large beds, two full bathrooms, equipped kitchen, dining room and a comfortable living room. Very quiet, with four leafy trees in the garden muting sounds from the outside world. The Santa María caters to young people's tastes, has a big range of cuisines and features 'colonial style' architecture given that it is in the town's Historic Center; it is just a 10 minute walk to the San Cosme Metro, with Zócalo just four stops down the line.

Guest favourite
A bright living area features a comfortable brown sofa, positioned near large glass doors that open to a balcony with views of lush greenery. The walls are adorned with two striking framed artworks, enhancing the modern decor of the space.
Serviced apartment in Condesa
4.81 out of 5 average rating, 474 reviews

King Loft with Balcony & Parque Mexico Views

-Modern, brand new building -Balcony with view of Parque México -Rooftop terrace and brand new gym with views of Parque México and Reforma -Fully-furnished unit designed for long stays and corporate travel -Free laundry facilities -Housekeeping service: Once a week for reservation of +7 nights Nido Parque Mexico is an incredible architectural accomplishment with the absolute best location in the entirety of Mexico City, on the corner overlooking Parque Mexico, in the heart of la Condesa. With a

Guest favourite
Apartment in Roma Norte
4.96 out of 5 average rating, 160 reviews

Breathtaking duplex in the heart of the Roma

With an unbeatable location in the heart of the Roma Norte neighborhood, is steps away from great cafes, restaurants and galleries. Thoughtfully newly decorated by a recognized European interior designer based in Mexico, the apartment is full of magical touches -art. The dining area will make you live an unforgettable experience. In the terrace you can relax and dine al fresco in complete peace and privacy. Unique apartment! King bedroom on the second floor, loft-style with a semi-open layout.

Guest favourite
A bright space features a spacious bed adorned with patterned pillows. A dining area with a wooden table and chairs is visible in the background, while the kitchen boasts minimalist cabinetry. Wood beams add character to the high ceiling, enhancing the open layout.
Loft in Juárez
4.88 out of 5 average rating, 484 reviews

Our praceful place, perfect oasis in the city.

Discover the City from this small and cozy oasis. A space full of light and with details that will make you feel in Mexico. The place is very quiet and the apartment lovingly decorated. As a host we can support you with whatever you need, do not hesitate to ask and if it is in our hands we will gladly do so. High ceilings, wooden beams and traditional pasta floors. A loft with a lot of character. The kitchen is fully equipped and the bathroom and its tub is an ideal way to end the day.

Top guest favourite
Flat in Roma Norte
5 out of 5 average rating, 14 reviews

Architect-Designed Duplex · Roma Norte

A duplex residence conceived by a recognized architecture studio and furnished by one of Mexico City’s leading design firms. Every material, finish, and object was selected with intention — nothing is accidental. Steps from Roma Norte’s best restaurants, cafés, and galleries. Everything you need is walkable; everything inside is intentional. Full kitchen, premium linens, fast Wi-Fi, and a host committed to one standard: every guest leaves wishing they’d stayed longer.

Top guest favourite
Townhouse in Roma Norte
4.97 out of 5 average rating, 132 reviews

Hidden 2BR Gem with Rooftop Terrace & Greenery

Welcome to Casa Chaya! At Casa Chaya, we have a unique obsession with plants, so you'll find lush greenery all around, creating a truly refreshing atmosphere. Your comfort, enjoyment, and connection with nature are our top priorities during your stay. We want you to experience and love this place as much as we do, so we are here to make your time a memorable one. We can't wait to host you and ensure you have a wonderful experience!

Superhost
A bright living area features a glass coffee table atop a colorful rug with intricate patterns. Two black armchairs frame the seating space, which includes a light-colored sofa adorned with textured pillows. Large windows provide a view of greenery outside, allowing natural light to fill the room.
Flat in Roma Norte
4.78 out of 5 average rating, 162 reviews

Incredible New Apartment in La Roma

Unbelievable 2 br apartment in a unique building designed by mexican architect Alberto Kalach. Located in La Roma this beautiful apartment has the perfect location to enjoy an incredible trip to Mexico City. You can walk to the best food, shopping and party spots while enjoying and amazing apartment where you can rest.

Guest favourite
An outdoor terrace is presented with a wooden pergola, casting dynamic shadows across a spacious wooden dining table surrounded by benches. A kitchen area is visible with a modern design, and various potted plants are arranged along the perimeter, enhancing the natural ambiance.
Loft in Coyoacán
4.94 out of 5 average rating, 634 reviews

ECO-ROOF with terrace in the heart of Coyoacán

Nice and cozy room with a private balcony in the heart of Coyoacán, one of the most picturesque and traditional neighborhoods in Mexico City. Located a 5-minute walk from downtown Coyoacan, traditional restaurants, cafes, craft bazaars, and museums.

Top guest favourite
The exterior of a two-story house is surrounded by lush greenery and vibrant planters. A small terrace features a white umbrella, where a person is seated, enjoying the garden view. A paved pathway leads to the entrance, enhancing the welcoming atmosphere.
Loft in Del Carmen
4.95 out of 5 average rating, 246 reviews

Loft Coyoacan Viveros (Bow)

A super special and very cozy place in the heart of Coyoacán! right next to Coyoacán nurseries, on Melchor Ocampo street Ideal for a couple with or without children who want to enjoy a pleasant stay or a good walk through the wonders of Coyoacán :)

Top guest favourite
A spacious living area features a light grey sofa adorned with decorative pillows. An intricate glass coffee table sits on a tiled floor, reflecting light from large windows framed by brick arches. Warm curtains complement the vibrant wall art and ceramic plates displayed nearby.
Home in Coyoacán
4.96 out of 5 average rating, 153 reviews

Colonial house with garden in the center of Coyoacán

Luxury colonial house, 350 meters from the center of Coyoacan. The house has a garden and terrace. We strive to make your stay perfect. If your stay is long, we have cleaning service included.

Guest favourite
A spacious sleeping area features a large bed with neutral bedding and a blue throw blanket. Wooden nightstands are placed on either side, while an open shelving unit stands in one corner. Soft lighting enhances the calm atmosphere against the gray walls.
Apartment in Iztapalapa
4.93 out of 5 average rating, 526 reviews

HB Flat (2 BR) 15min Airport/10min Estadio GNP

Departamento completo a 15 min del aeropuerto, 10 min del Foro Sol, Palacio de los Deportes y Autodromo Hermanos Rodriguez en coche. 2 recámaras con escritorio, baño, cocina y sala - comedor.

Guest favourite
A lush field of nopales occupies the foreground, displaying a vibrant green landscape. In the background, rustic red-roofed cabins are visible against a backdrop of rolling hills and a wide sky, offering a glimpse of the tranquil countryside.
Cabin in San Lorenzo Tlacoyucan
4.87 out of 5 average rating, 30 reviews

Resting cabin in Milpa Alta

🤠 Enjoy the countryside in the Milpa Alta ecological reserve, among nopaleras and magueyes, live with the people of the countryside and enjoy beautiful views of the Valley of Mexico.

Popular amenities for Santa Cruz holiday rentals

  1. Airbnb
  2. Mexico
  3. Santa Cruz