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Holiday rentals in Santa Cruz

Find and book unique accommodation on Airbnb

Top-rated holiday rentals in Santa Cruz

Guests agree: these stays are highly rated for location, cleanliness and more.

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Top guest favourite
A cozy living space features dark walls adorned with colorful artwork. Comfortable seating includes a sofa and two lounge chairs, positioned around a small table. Natural light filters through large windows, illuminating the room and highlighting wooden flooring.
Flat in Santa María La Ribera
4.91 out of 5 average rating, 563 reviews

Independent apartment on 3 levels and 2 bathrooms.

New apartment on three levels with splendid views of a beautiful Mexican-Andalusian garden. Two large beds, two full bathrooms, equipped kitchen, dining room and a comfortable living room. Very quiet, with four leafy trees in the garden muting sounds from the outside world. The Santa María caters to young people's tastes, has a big range of cuisines and features 'colonial style' architecture given that it is in the town's Historic Center; it is just a 10 minute walk to the San Cosme Metro, with Zócalo just four stops down the line.

Guest favourite
A vibrant red house is surrounded by lush greenery, showcasing diverse plants in large pots. The exterior features unique architectural details and large arched windows. A stone pathway guides the way to the entrance, offering a welcoming glimpse of the inviting atmosphere.
Cottage in Santo Domingo Ocotitlán
4.92 out of 5 average rating, 142 reviews

Tepoztlán in the mountains. Magical and peaceful!

The house is situated in a beautiful valley nestled in the Tepozteco mountain range. The location is peaceful, quiet and safe. Its architecture is reminiscent of North African desert houses, offers comfortable spaces with private areas suitable for two couples or one family. The living and dining rooms open onto the garden. All the necessary amenities for cooking and enjoying meals are provided. Whether you want to sleep, relax, meditate, walk, or read, this is the perfect place! good internet

Guest favourite
A modern cabin is nestled among tall trees, showcasing large windows that invite natural light. A hammock hangs nearby, providing a relaxing spot. The surrounding terrain is covered with natural foliage, creating a tranquil outdoor setting.
Hut in Tepoztlán
4.95 out of 5 average rating, 185 reviews

Ivan's little cabin

Disfruta en medio de la naturaleza en el bosque. Por la mañana podrás escuchar el canto de los pájaros con un café, aprovechar el tiempo para conectar con tu tribu y gozar el día como pocas veces se puede. La cabaña está ubicada a 15 min del centro de Tepoztlán en vehículo o a 5 min caminando al transporte que te llevará al centro. También podrás evitar todo el tráfico ya que no necesitas cruzar el centro. Muy conveniente en puentes y fines. La propiedad está cercada. La vegetación varía.

Superhost
A modern open-concept living space is presented, featuring large glass doors that connect to a serene outdoor area. The kitchen, adorned with wooden accents, leads to a cozy seating area. Lush greenery surrounds a small plunge pool, enhancing the tranquil atmosphere.
Tiny home in Tepoztlán
4.92 out of 5 average rating, 230 reviews

Loft de Lujo con Jacuzzi Privado en Tepoztlán

Welcome to Ixaya, a luxury loft designed to offer comfort, privacy and an atmosphere of deep relaxation in the middle of Tepoztlán's nature. Here you will find an ideal retreat to disconnect: king size bed, private heated Jacuzzi (extra cost), equipped kitchen, large windows and two exclusive gardens that fill each space with light and serenity. Located in a quiet and safe residential development, just 12 minutes from downtown, you can enjoy its unique energy.

Top guest favourite
A serene outdoor terrace features a round glass table surrounded by four ornate chairs. Lush greenery and colorful flower pots adorn the walls, adding vibrancy. A soft umbrella provides shade, while a staircase in the background leads to additional levels of the property.
Flat in Tepoztlán
4.94 out of 5 average rating, 507 reviews

Downtown Tepoztlán apartment | Terrace & WiFi

This beautiful and cozy apartment; we are experienced hosts, our goal is to make your stay unique and unbeatable. *Located a block and a half from downtown Tepoz: a unique destination thanks to its holistic and energetic atmosphere. *Ideal to discover and immerse yourself in the local environment with your partner, family or friends. *Spacious rooms, equipped kitchen, dining room and terrace. *Internet to work from home. *Parking. *Pet Friendly.

Top guest favourite
The living area is furnished with a soft blue sofa and a wooden coffee table on a patterned rug. A flat-screen television is mounted on the wall, with a modern cabinet underneath. The space is brightened by natural light from a nearby window.
Apartment in Ignacio Zaragoza
4.93 out of 5 average rating, 181 reviews

Large penthouse near Foro Sol GNP Airport

A LARGE APARTMENT 5 MINUTES FROM MEXICO CITY INTERNATIONAL AIRPORT 15 MINUTES FROM THE CITY CENTER ONE BLOCK FROM THE SOL FORUM TWO FLOORS 145 M2 WITH PRIVATE ROOF GARDEN AREA TWO FULL BATHROOMS VERY SOFT BEDS VERY WELL CONNECTED METRO 5 MINUTES SAFE QUIET STREET FULLY EQUIPPED EVERYTHING FIRST CLASS TO SPEND A COMFORTABLE AND PEACEFUL STAY CAN ACCOMMODATE 5 PEOPLE COMFORTABLY ALL SERVICES ARE TOTALLY WELCOME FROM ANYWHERE IN THE WORLD.

Superhost
A cozy bedroom features a spacious bed with a soft grey headboard and decorative cushions. A sleek bedside lamp provides gentle illumination, while modern wooden cabinetry adds warmth to the space. A grey armchair is positioned nearby, complemented by delicate white flowers in the foreground.
Loft in Tlalpan
4.87 out of 5 average rating, 915 reviews

Punto Lofts Periférico Sur (South Peripheral Point Lofts)

Punto Lofts Periférico Sur is a modern concept with 18 fully equipped lofts, ideal for short or long stays. Each loft accommodates up to 3 people and has a queen size bed and sofa bed, offering comfort and rest. Enjoy 24/7 reception, digital key access, and high standards of cleanliness and safety. Located on Periférico Sur, opposite the Azteca Stadium, with easy access to hospitals, restaurants and shopping centers.

Guest favourite
A terrace with elegant seating offers scenic views of the mountains and sunset. A small round table displays two glasses of red wine and a bottle. A spacious bed is visible through glass doors, enhancing the indoor-outdoor connection.
Villa in Tepoztlán
4.96 out of 5 average rating, 170 reviews

Casa Aluna - Oasis in the Mountain, Premium Villa

Casa Aluna is built in the heart of the mountain on a big compound with 2 independent villas. It is a place to enjoy the surrounding nature and disconnect from the city. Amazing views of the sunset and Tepoztlan mountains. You can enjoy nature walks nearby and visit local restaurants for a culinary experience, we are located 15 minutes from downtown Tepoztlan and Mexico City (80 minutes).

Guest favourite
Flat in Condesa
4.84 out of 5 average rating, 1,714 reviews

Chic & Equipped Apt | Rooftop+Gym+B/Center+Lounge

This stylish apartment in the heart Roma Norte and Condesa offers the perfect setup for digital nomads—ultra-fast Wi-Fi, a sleek workspace, and steps from the trendiest cafés, restaurants, and nightlife. Enjoy top-tier amenities: a business center, a full gym, a game room, and a rooftop with stunning views. Stay productive, stay inspired, and experience CDMX like a local.

Guest favourite
A charming mini cabin is displayed, featuring a brick exterior and a welcoming porch. Two red Adirondack chairs are positioned on the manicured lawn, surrounded by greenery. The clear blue sky and sunlight enhance the tranquil setting of this inviting retreat.
Cabin in 012
4.95 out of 5 average rating, 120 reviews

cozy tiny house, adorable casa!

Relájate en pareja o con toda la familia en este alojamiento donde la tranquilidad se respira, adorable mini cabaña ubicada en zona boscosa, rodeada de cedros, un lugar ideal para descansar, hacer una carne asada, picnic o realizar home office. Pero no por eso dejar de disfrutar de tus series o películas favoritas en Netflix, Prime Video, Disney y/o partidos de futbol

Superhost
A spacious living area is shown with large glass doors that open to stunning mountain views. Natural light illuminates the room, featuring rattan chairs and a rustic table. A woven rug adds texture to the concrete floor, enhancing the connection with nature.
Cottage in Santo Domingo Ocotitlán
4.86 out of 5 average rating, 389 reviews

Tepoztlán Mountain House with the best mountain view

Enjoy the scenery, nature, and unplug from civilization. The house is well integrated into the landscape, built with local stone. We offer everything you need to enjoy a very relaxing stay. The view is spectacular and the sunset unforgettable. Ideally designed for two people but can accommodate a maximum of four people.

Top guest favourite
A charming outdoor patio is surrounded by vibrant greenery and a blue-walled house. A round glass table is complemented by six white metal chairs, creating an inviting space for dining or gathering. Potted plants and flowers add color to the serene environment.
Home in Coyoacán
4.97 out of 5 average rating, 103 reviews

Casa Omac | Colonial house with two patios

Typical colonial house, located in the most picturesque and emblematic street of Coyoacán. The style is reminiscent of Frida Kahlo's Blue House, which is a few minutes' walk away. Organized around a large internal patio, the house has 5 double rooms and can host up to 10 people, making it ideal for groups and families.

Popular amenities for Santa Cruz holiday rentals

  1. Airbnb
  2. Mexico
  3. Santa Cruz