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Holiday rentals in Santa Cruz

Find and book unique accommodation on Airbnb

Top-rated holiday rentals in Santa Cruz

Guests agree: these stays are highly rated for location, cleanliness and more.

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Top guest favourite
Flat in Santa María La Ribera
4.91 out of 5 average rating, 563 reviews

Independent apartment on 3 levels and 2 bathrooms.

New apartment on three levels with splendid views of a beautiful Mexican-Andalusian garden. Two large beds, two full bathrooms, equipped kitchen, dining room and a comfortable living room. Very quiet, with four leafy trees in the garden muting sounds from the outside world. The Santa María caters to young people's tastes, has a big range of cuisines and features 'colonial style' architecture given that it is in the town's Historic Center; it is just a 10 minute walk to the San Cosme Metro, with Zócalo just four stops down the line.

Guest favourite
Cottage in Tepoztlán
4.92 out of 5 average rating, 142 reviews

Tepoztlán in the mountains. Magical and peaceful!

The house is situated in a beautiful valley nestled in the Tepozteco mountain range. The location is peaceful, quiet and safe. Its architecture is reminiscent of North African desert houses, offers comfortable spaces with private areas suitable for two couples or one family. The living and dining rooms open onto the garden. All the necessary amenities for cooking and enjoying meals are provided. Whether you want to sleep, relax, meditate, walk, or read, this is the perfect place! good internet

Guest favourite
A modern living area features a curved black sectional sofa adorned with decorative pillows. Large floor-to-ceiling windows provide views of a lush patio with tropical plants. A wooden coffee table complements the relaxed atmosphere, while colorful wall art adds interest to the room.
Apartment in Roma Norte
4.96 out of 5 average rating, 161 reviews

Breathtaking duplex in the heart of the Roma

With an unbeatable location in the heart of the Roma Norte neighborhood, is steps away from great cafes, restaurants and galleries. Thoughtfully newly decorated by a recognized European interior designer based in Mexico, the apartment is full of magical touches -art. The dining area will make you live an unforgettable experience. In the terrace you can relax and dine al fresco in complete peace and privacy. Unique apartment! King bedroom on the second floor, loft-style with a semi-open layout.

Guest favourite
Hut in Los Ocotes
4.95 out of 5 average rating, 185 reviews

Ivan's little cabin

Disfruta en medio de la naturaleza en el bosque. Por la mañana podrás escuchar el canto de los pájaros con un café, aprovechar el tiempo para conectar con tu tribu y gozar el día como pocas veces se puede. La cabaña está ubicada a 15 min del centro de Tepoztlán en vehículo o a 5 min caminando al transporte que te llevará al centro. También podrás evitar todo el tráfico ya que no necesitas cruzar el centro. Muy conveniente en puentes y fines. La propiedad está cercada. La vegetación varía.

Superhost
An outdoor view showcases a compact, modern loft surrounded by greenery. A small private pool is set on a wooden deck, while large glass doors offer a glimpse into the open living space. Lush plants enhance the tranquil atmosphere of the surroundings.
Tiny home in Los Ocotes
4.92 out of 5 average rating, 230 reviews

Luxury Loft, Privacy and Nature in Tepoztlán

Welcome to Ixaya, a luxury loft designed to offer comfort, privacy and an atmosphere of deep relaxation in the middle of Tepoztlán's nature. Here you will find an ideal retreat to disconnect: king size bed, private heated Jacuzzi (extra cost), equipped kitchen, large windows and two exclusive gardens that fill each space with light and serenity. Located in a quiet and safe residential development, just 12 minutes from downtown, you can enjoy its unique energy.

Top guest favourite
A private roof garden is depicted, featuring a seating area with two armchairs and a small table. A glass of beverage sits on the table, surrounded by urban views and evening lights. A glass railing provides unobstructed sightlines of the cityscape.
Flat in Granjas México
4.96 out of 5 average rating, 106 reviews

Next to the Autodromo with parking

You have everything in the same place. We are located next to the Autódromo Hermanos Rodríguez (Formula 1), the Foro Sol, and the Harp Helu Stadium. 5 minutes from the airport, shopping centers, 25 minutes from the capital's main square and the IPN academic unit of UPIICSA. With a sports field next door, a gym on the premises, and a private roof garden. Peace and quiet inside the apartment and excellent views of the volcanoes that shelter the city.

Top guest favourite
Apartment in Ignacio Zaragoza
4.93 out of 5 average rating, 181 reviews

Large penthouse near Foro Sol GNP Airport

A LARGE APARTMENT 5 MINUTES FROM MEXICO CITY INTERNATIONAL AIRPORT 15 MINUTES FROM THE CITY CENTER ONE BLOCK FROM THE SOL FORUM TWO FLOORS 145 M2 WITH PRIVATE ROOF GARDEN AREA TWO FULL BATHROOMS VERY SOFT BEDS VERY WELL CONNECTED METRO 5 MINUTES SAFE QUIET STREET FULLY EQUIPPED EVERYTHING FIRST CLASS TO SPEND A COMFORTABLE AND PEACEFUL STAY CAN ACCOMMODATE 5 PEOPLE COMFORTABLY ALL SERVICES ARE TOTALLY WELCOME FROM ANYWHERE IN THE WORLD.

Superhost
Loft in Olímpica
4.87 out of 5 average rating, 915 reviews

Punto Lofts Periférico Sur (South Peripheral Point Lofts)

Punto Lofts Periférico Sur is a modern concept with 18 fully equipped lofts, ideal for short or long stays. Each loft accommodates up to 3 people and has a queen size bed and sofa bed, offering comfort and rest. Enjoy 24/7 reception, digital key access, and high standards of cleanliness and safety. Located on Periférico Sur, opposite the Azteca Stadium, with easy access to hospitals, restaurants and shopping centers.

Top guest favourite
Flat in Mexico City
4.85 out of 5 average rating, 1,703 reviews

Cool Apt w/Rooftop in La Roma | Gym+Work Lounge

This stylish apartment in Roma Norte offers the perfect setup for digital nomads—ultra-fast Wi-Fi, a sleek workspace, and steps from Condesa’s trendiest cafés, restaurants, and nightlife. Enjoy top-tier amenities: a business center, a full gym, a game room, and a rooftop with stunning views. Stay productive, stay inspired, and experience CDMX like a local.

Guest favourite
Home in Roma Norte
4.88 out of 5 average rating, 156 reviews

New Casa Rosa in the heart of Roma neighborhood

A beautiful and newly remodeled pink house in the heart of Roma neighborhood. A home away from home to spend a few days or a long season near historic sites, shops, and local restaurants in a neighborhood with attitude. All the amenities in a house with personality and impeccable architecture and interior design.

Guest favourite
Loft in Santa Catarina
4.94 out of 5 average rating, 634 reviews

ECO-ROOF with terrace in the heart of Coyoacán

Nice and cozy room with a private balcony in the heart of Coyoacán, one of the most picturesque and traditional neighborhoods in Mexico City. Located a 5-minute walk from downtown Coyoacan, traditional restaurants, cafes, craft bazaars, and museums.

Top guest favourite
Home in Santa Catarina
4.96 out of 5 average rating, 153 reviews

Colonial house with garden in the center of Coyoacán

Luxury colonial house, 350 meters from the center of Coyoacan. The house has a garden and terrace. We strive to make your stay perfect. If your stay is long, we have cleaning service included.

Popular amenities for Santa Cruz holiday rentals

  1. Airbnb
  2. Mexico
  3. Santa Cruz