
Holiday rentals in Santa Cruz
Find and book unique accommodation on Airbnb
Top-rated holiday rentals in Santa Cruz
Guests agree: these stays are highly rated for location, cleanliness and more.

Independent apartment on 3 levels and 2 bathrooms.
New apartment on three levels with splendid views of a beautiful Mexican-Andalusian garden. Two large beds, two full bathrooms, equipped kitchen, dining room and a comfortable living room. Very quiet, with four leafy trees in the garden muting sounds from the outside world. The Santa María caters to young people's tastes, has a big range of cuisines and features 'colonial style' architecture given that it is in the town's Historic Center; it is just a 10 minute walk to the San Cosme Metro, with Zócalo just four stops down the line.

Breathtaking duplex in the heart of the Roma
With an unbeatable location in the heart of the Roma Norte neighborhood, is steps away from great cafes, restaurants and galleries. Thoughtfully newly decorated by a recognized European interior designer based in Mexico, the apartment is full of magical touches -art. The dining area will make you live an unforgettable experience. In the terrace you can relax and dine al fresco in complete peace and privacy. Unique apartment! King bedroom on the second floor, loft-style with a semi-open layout.

Kaya Kalpa-Organic Designer Apartment in Condesa
After a year-long remodeling project, I’m thrilled to present this personal residence Kaya Kalpa. Every inch of the property has been thoughtfully remodeled. Ideal place for artists, wanderers, all walks of life practitioners to come reset, reflect, and create. The space is located on Amsterdam street in Condesa, one block from Parque Mexico. You’ll find all nice restaurants, cafes, and stores downstairs. Big supermarket, local Mercado, metro station…all within 5 minutes walking distance.

Our praceful place, perfect oasis in the city.
Discover the City from this small and cozy oasis. A space full of light and with details that will make you feel in Mexico. The place is very quiet and the apartment lovingly decorated. As a host we can support you with whatever you need, do not hesitate to ask and if it is in our hands we will gladly do so. High ceilings, wooden beams and traditional pasta floors. A loft with a lot of character. The kitchen is fully equipped and the bathroom and its tub is an ideal way to end the day.

Architect-Designed Duplex · Roma Norte
A duplex residence conceived by a recognized architecture studio and furnished by one of Mexico City’s leading design firms. Every material, finish, and object was selected with intention — nothing is accidental. Steps from Roma Norte’s best restaurants, cafés, and galleries. Everything you need is walkable; everything inside is intentional. Full kitchen, premium linens, fast Wi-Fi, and a host committed to one standard: every guest leaves wishing they’d stayed longer.

Hidden 2BR Gem with Rooftop Terrace & Greenery
Welcome to Casa Chaya! At Casa Chaya, we have a unique obsession with plants, so you'll find lush greenery all around, creating a truly refreshing atmosphere. Your comfort, enjoyment, and connection with nature are our top priorities during your stay. We want you to experience and love this place as much as we do, so we are here to make your time a memorable one. We can't wait to host you and ensure you have a wonderful experience!

EXCLUSIVE SUITE IN CASA DE 1905. GREAT LOCATION
cozy suite of 60 m2 located in a unique set of houses built in 1905 in havre, one of the most exclusive streets and with the best gastronomic offer of the Juarez colony. the house was completely restored adding contemporary elements to its typically Porfirian architecture. the space has been furnished with original pieces in the modern mid-century style and other finds of our searches by the antique dealers of the city.

ECO-ROOF with terrace in the heart of Coyoacán
Nice and cozy room with a private balcony in the heart of Coyoacán, one of the most picturesque and traditional neighborhoods in Mexico City. Located a 5-minute walk from downtown Coyoacan, traditional restaurants, cafes, craft bazaars, and museums.

Loft Coyoacan Viveros (Bow)
A super special and very cozy place in the heart of Coyoacán! right next to Coyoacán nurseries, on Melchor Ocampo street Ideal for a couple with or without children who want to enjoy a pleasant stay or a good walk through the wonders of Coyoacán :)

A little house
Una Casita is located on a quiet street in the heart of Condesa. It is surrounded by delicious restaurants, fantastic coffee, and leafy walks. Hosted by a Bosnio-Mexican couple that is madly in love with this beautiful city.

Colonial house with garden in the center of Coyoacán
Luxury colonial house, 350 meters from the center of Coyoacan. The house has a garden and terrace. We strive to make your stay perfect. If your stay is long, we have cleaning service included.

HB Flat (2 BR) 15min Airport/10min Estadio GNP
Departamento completo a 15 min del aeropuerto, 10 min del Foro Sol, Palacio de los Deportes y Autodromo Hermanos Rodriguez en coche. 2 recámaras con escritorio, baño, cocina y sala - comedor.
Popular amenities for Santa Cruz holiday rentals
Other great holiday rentals in Santa Cruz

Come & Dream in Quetzalcoatl`s Nest

Incredible views, Balcony, Design, Rooftop & Gym

Apartment Near Airport T1

Private and complete house, Magüe House

High Park Sur Apartment | Walk to the Azteca Stadium

Design Apartment in Coyoacán | Excellent Location

Ground floor apartment with large garden in Coyoacán

Sunny Luxury Penthouse in Roma Norte
Destinations to explore
- Reforma 222
- The Angel of Independence
- Departamento
- Arena México
- Palacio de Bellas Artes
- Val'Quirico
- Monument To the Revolution
- Alameda Central
- World Trade Center Mexico City
- Teatro Metropólitan
- Pepsi Center Wtc
- Auditorio Nacional
- Embajada De Los Estados Unidos De América
- Basilica of Our Lady of Guadalupe
- Constitution Square
- Aztec Stadium
- Mexico City Arena
- Foro Sol
- Museo Soumaya
- Frida Kahlo Museum
- Six Flags Mexico
- Autódromo Hermanos Rodríguez
- Palacio de los Deportes
- Las Estacas Parque Natural





