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Holiday rentals in Santa Isabel District

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Top-rated holiday rentals in Santa Isabel District

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A bright sleeping area features a spacious bed covered with a patterned blanket. Two windows allow natural light and offer views of the lush greenery outside. A ceiling fan adds comfort, while sliding glass doors lead to a covered patio.
Home in Garrote
4.67 out of 5 average rating, 9 reviews

Cozy Cottage with garden AC/WIFI in Puerto Lindo

Discover the tropical charm of Casa Mariposa, nestled in the heart of Portobelo National Park. This enchanting retreat offers you the opportunity to explore the wonders of the Caribbean just minutes from the idyllic islands of Mamey and Isla Grande. You can also visit the historic ruins in the center of Portobelo and Nombre de Dios, both UNESCO World Heritage sites. Casa Mariposa is the ideal base to experience the magic of Panama's Costa Arriba. Perfect for a unique blend of nature and history!

A colorful hammock is positioned on the patio, with a view of the ocean and a vibrant sunrise in the background. Tall palm trees frame the scene, and soft grass gently carpeted the ground, reflecting a tranquil and inviting outdoor space.
Cottage in Palenque
4.87 out of 5 average rating, 90 reviews

Beachfront House in Caribbean sandy beach

Enjoy this rustic and cozy cottage with its almost private beach surrounded by beautiful palm trees along the whole area. With 2 oceanview bedrooms, 2 full bathrooms and a third bedroom in a mezzanine. Has a patio with a built in uruguayan parrilla, ideal for BBQs. Step in beautiful white sand and bath in crystal clear water. Coconut breakfasts watching the sunrise become a routine in this paradise. - This is a rural setting. Not a 5 star hotel. Insects and small animals can be around.

Home in Playa Chiquita
5 out of 5 average rating, 6 reviews

Caribbean Jungle Beach House

Secluded loft beach house on 7 hectares of jungle with pristine beach. Enjoy the peaceful tranquility of coconut palm tree covered golden sand beach with shallow warm water great for swimming and body surfing. Lounge chairs, barbecue, kayaks, snorkel masks, boogie boards, hammocks and a fire pit for beach bonfires under the starry night sky all available. Great for families, couples or groups of friends. Delicious Panamanian food made to order on site. Tent camping (glamping) also available.

Guest favourite
Home in La Guaira
4.82 out of 5 average rating, 34 reviews

Bella Casa, Caribbean Sea, Juan Gallego (waterfront)

Hermosa Casa de Playa, frente al mar caribe, para descansar y relajarse al 100%. La Casa cuenta con una ubicación privilegiada, mantiene 4 habitaciones (una de ellas cuenta con una mampara para dividir de la sala y ampliar esa área en caso que se desee), sala, comedor, terraza privada, frente a Isla Grande. 4 habitaciones. 3 tienen TV con cable y una TV extra en la sala. Todas con con Aire Acondicionado. Cuenta con 2 baños completos. Cocina equipada y lista para disfrutar y Wifi

Home in Palenque
4.61 out of 5 average rating, 36 reviews

Lagoon & Oceanfront Retreat · Infinity Pool

Welcome to our beachfront paradise in Palenque, Colón, Panama! Nestled along the stunning coastline, this spacious and inviting house offers the perfect retreat for your group getaway. With direct beach access, you'll wake up to the soothing sounds of the waves and the breathtaking views of the ocean right outside your doorstep. The house is located by the beach, in a forest area. You may experience presence of insects during night-time. Insect repellent is always recommended.

Guest favourite
A hammock sways gently between posts, overlooking calm waters that reflect a clear blue sky. In the distance, a lush island is visible, providing a picturesque backdrop. The green grass leads up to the water's edge, creating a serene outdoor space.
Flat in Juan Gallego
4.87 out of 5 average rating, 147 reviews

Pebos Reef Apt 2 · Beachfront · Sea View Terrace

This spectacular beachfront property is ideally situated with an incredible view of neighboring islands, fishing friendly waters, and mesmerizing snorkeling spots for children and adults to enjoy. Monkey greetings from the jungle adjacent, octopus and colorful native fish inhabited waters, and lazy bear sloth sightings are all part of your daily experiences here at Pebos Reef! If you are lucky you will even see dolphins from the terrace ! A terrace on the sea is all you need.

Guest favourite
An outdoor patio is visible, featuring a wooden table and benches, with a view of the ocean in the background. The well-maintained lawn leads to a private beach area, framed by palm trees under a clear blue sky.
Home in La Guaira
5 out of 5 average rating, 5 reviews

Lovely Apartment in Puerto Lindo / 2 of 2

Ubicada en Puerto Lindo, entre La Guaira y Linton Bay, nuestra casa ofrece un refugio ideal para los amantes del buceo y la aventura. Disfruta de paseos en lancha a Isla Mamey, Isla Grande y más. Con acceso a una playa privada, es el lugar perfecto para relajarte o practicar deportes acuáticos. Totalmente equipada, es ideal tanto para una escapada de fin de semana como para largas estancias. Disfruta de la belleza del Caribe panameño en un entorno único.

A spacious terrace features various hammocks in vibrant colors, providing a comfortable resting area. The area is shaded by an overhead roof and surrounded by green grass and tropical plants, creating an inviting outdoor space for relaxation and leisure.
Home in La Guaira
4.5 out of 5 average rating, 6 reviews

Oceanfront Villa on Isla Grande

Enjoy an oceanfront villa. No driving or walking to the beach. Villa Espe is just steps away from a spectacular and quiet Caribbean beach with white sand and crystal clear waters. The house is surrounded by a large patio where children can play and run with their pets, and the large oceanfront terrace has hammocks to relax and unwind. The entire property has a perimeter fence, surveillance cameras and private parking for added security.

Guest favourite
The exterior features a spacious grassy area leading up to a two-story structure. A covered seating area is situated on the right, with several lounge chairs arranged for relaxation. The glistening sea is visible in the background, framed by palm trees against a clear blue sky.
Home in Viento Frío
5 out of 5 average rating, 8 reviews

Casa Canalú

Enjoy the sounds of the sea when you stay at this unique place. The sea in front of the property is like a natural pool. The property is located six meters from the sea so you can always enjoy the sea breeze from a hammock. Those who like to cook will have a fully equipped kitchen. The 3 comfortable rooms, which are separated from each other, have air conditioning, fans and WiFi. Parking for several cars. Pedal boat, Kayak, Canoe

Guest favourite
An aerial view showcases the property nestled between two natural beaches, surrounded by lush greenery. Calm waters and rocky formations are visible nearby, alongside beachside features that highlight the area's tropical environment.
Villa in Palenque
5 out of 5 average rating, 10 reviews

Beach Front House Surrounded by 2 Private Beaches

La propiedad esta rodeada de dos playas naturales. Preserva una selva primaria con múltiples clases de arboles endémicos del área que sirven de alimento a los aulladores, titis, perezosos y muchas aves en especial tucanes que vienen a comer uvitas tropicales. Tenemos un camino interno para observar la selva. Entre Marzo-Mayo y Agosto-Oct se observa la migración de aves.

An indoor space features a long table draped in white cloth, showcasing a variety of beverages. Large windows frame a view of the ocean and palm trees, allowing natural light to fill the area. Soft lighting enhances the welcoming atmosphere.
Chalet in Viento Frío
5 out of 5 average rating, 4 reviews

Spacious seaside villa

Duplex home. Great for events or groups for short stays. Equipped for families on long stays. Beach without sea urchins or stones. Waves and sea breeze on one side; and on the other side, the town center, the park and a century-old church. Village with annual celebrations such as "Race Day". I can give you an offer for 4 people, for a single night or for less.

Home in Palenque
4.67 out of 5 average rating, 3 reviews

Casa Palenque Panama

Disfruta de una espectacular casa frente al mar, ideal para grupos y familias de hasta 14 personas. Relájate con vistas directas a la playa, amplios espacios interiores y exteriores, y todas las comodidades para una estancia inolvidable. Perfecta para descansar, convivir y crear recuerdos únicos con el sonido del mar como fondo. Somos pet friendly.

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