Holiday rentals in Santa María

Disfruta una Casa de Playa frente al mar, patio

Playa El Jobo is a magical place, special for connecting with nature and resting. It is oceanfront at a height of 9 meters, which allows you to receive the cool sea breeze. The property has a wooden house with a first floor and an upper floor. On the ground floor you will find the kitchen, two full bathrooms, two outdoor showers and a covered space with hammocks. Upstairs there is a large balcony with hammocks, two bedrooms, a living area and two bathrooms. There is good lighting, natural ventilation and A/C

A 5 min del Valle I Domo No. 7-Cafe gratis

🌄 Domo en El Valle – Naturaleza, paz y vistas increíbles • 🆕 Domo nuevo cama Queen • 🚿 Baño interno privado (nada compartido) • 🌬️ Clima fresco de montaña todo el año • 🌿 Rodeado de vegetación • 🌄 Vistas increíbles para desconectar • 🐶 1 mascota pequeña permitida • ❄️ Si hay Nevera, microondas y cafetera (no hay cocina) • ☕ Café, azúcar y crema de cortesía • 🚗 A 5 min antes de El Valle (últimos dos minutos es de piedra, pero es para todo carro) • 🕒 Check-in 3 pm | 🕛 Check-out 12 md

3BR • 10 Min Drive to Beach • Pool • BBQ • WiFi

🌿 Escape the city chaos at this peaceful home located in the serene PH Sendero de Santa Mónica community, right in the heart of Panama’s Pacific Riviera—just minutes from the area's best beaches. 🏡 Full private house with 3 bedrooms, perfect for families and couples seeking comfort, privacy, and a natural setting. 🌞 Spacious private garden with a pool, BBQ area, hammocks, and outdoor furniture for total relaxation. 🛋 Air-conditioned living and dining areas with open, breezy spaces.

Cheerful 3 bedroom countryside Villa with pool.

Forget your worries in this spacious and serene space. This 2 hectares villa includes an 185 square meters house, with 3 air conditioned bedrooms. In addition it includes a swimming pool and 40 square meter ranch. Bedrooms have in total 9 beds, accomodating 12 people. There are 3. 5 bathrooms, internet and hot water. Total perimeter of land is fenced, including an electric gate at the entrance. The price includes the presence of an employee who will support you during your stay.

Coastal Paradise

Welcome to Nikki Residence Panama, a charming apartment located in the beautiful Pacific. This spacious accommodation has **2 bedrooms and 2 bathrooms, perfect for comfortably accommodating up to **6 people**. Each room is designed to offer rest and tranquility, with comfortable beds and enough space for everyone to feel at home. Nikki Residence Panama is the perfect place to disconnect and enjoy an unforgettable vacation. We look forward to seeing you!

Peaceful home w/ spacious living & office area

Spacious and peaceful home in a safe area of Santiago. 4 bedrooms (ideal for families and groups), bright living-dining area and large kitchen to share with family or friends, plus a private office for working comfortably. High-speed Wi-Fi, air conditioning and fans in all rooms, fully equipped kitchen, washer/dryer, and safe for valuables. Self check-in with smart lock, parking for several cars, and a coffee station with board games and karaoke.

Country House with Pool in La Enea de Guararé

Far from the capital city, come and enjoy Panamanian folklore in a rustic but cozy space, living an indigenous experience. Relax in the pool or rest in a hammock, breathe fresh air, near the sea, surrounded by spacious and natural gardens for a good walk. Close to the Port of Guararé where you can enjoy the best seafood and drinks or enjoy the heart of the best folklore event highlighting the traditions and the best Panamanian skirts.

Ananda fully-equipped dome

PRANA hOMe invites you to enjoy a unique glamping experience in our fully equipped and very comfortable geodesic dome. We are located in the heart of a beautiful tourist region just 1.5 hours from the capital. Guests can enjoy both the many beaches of the bay and the coolness of the mountain in El Valle de Anton. Prana hOMe is the perfect place to relax in this original home nestled in the heart of nature.

Beachfront Loft in Farallón

Wake up to the ocean in this beautiful beachfront loft in Farallón, located in the exclusive Miramar Loft next to the Decameron Hotel. Relax on the balcony with sea views, enjoy the pool, and walk to the beach with private cabanas on the sand. The apartment offers 2 bedrooms, a full kitchen, A/C throughout, and fast Wi-Fi. Just 2 hours from Panama City. Book now and live the beach experience you deserve!

Cabaña del Sol en Finca Namuiki by the River

Spectacular contemporary style villa surrounded by local flowers and woods. The villas design enhances the relationship with the outside environment with panoramic windows which are found in the dining room and kitchen, this offers an awesome view of the mountains and green flora. The villa is located in a organic quiet farm, with abundant vegetation and great presence of birds.

k* Casa Matilde | 2BR Santa Fe Retreat by River

Escape to Casa Matilde, a renovated 100 m² home in Santa Fe de Veraguas. With 2 bedrooms and 3 beds (1 queen & 2 twins), it’s perfect for families or remote workers. Enjoy a bright living room, modern bath with hot water, A/C, and fast Starlink Wi-Fi. Relax by the private creek, explore the river just 200 m away, and take in mountain views—all with total privacy and comfort.

Comfortable, fenced and safe house.

Enjoy the simplicity of this spacious, quiet and centrally located place at Casa las Hamacas. You can enjoy the pleasant Penonomeño climate. A place close to everything, shopping malls, schools, hospital, mountains, rivers and beaches. Both rooms feature A/C to ensure your rest. A few minutes away from the Pan-American Highway.