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Holiday rentals in Santa María

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Top-rated holiday rentals in Santa María

Guests agree: these stays are highly rated for location, cleanliness and more.

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Top guest favourite
A serene evening scene features the bohío cottage with its thatched roof, surrounded by lush greenery and potted plants. The moon is visible in the sky above, casting a gentle glow on the outdoor area, near the tranquil pool reflecting the soft outdoor lighting.
Place to stay in Santa Clara
5 out of 5 average rating, 23 reviews

Paradise from ocean to jungle. Bohío cottage

Welcome to our beach house 850meters to beautiful pacific beach & 3 beach restaurants . Our house is gated and in a safe area .Many areas to visit nearby from surf areas to crater town in the mountains ! Hikes , Canyons , waterfalls ! Coronado is a 35 min drive with all conveniences .New mall is 10 min drive to grocery store , large drugstore. Fish market is 5 min . Seasonal riohato airport 5 min. . Our 1/4 acre property & house is on a country lane with some lovely estates surrounding it.

Superhost
A single-story house is nestled beneath a large tree, featuring a tiled roof and a covered parking area. Surrounding greenery includes bushes and ornamental plants, enhancing the natural setting. The house is positioned to provide a sense of privacy and tranquility.
Home in Chitre
4.86 out of 5 average rating, 63 reviews

Country House Like in the City / La Casita

Casa fresca, con árboles y naturaleza. Áreas amplias para descansar. Ubicación céntrica, cerca de malls, restaurantes, estación de buses y ciclovía. Entrada privada, estacionamientos, cocina completa, mobiliario completo, baño, TV HD con cable, AC en recámara, agua caliente y Wi-Fi. ENG, PORT, FRAN and ITA Spoken! Ahora, Chitré, tiene un problema con el agua: no está potable; tenemos 50% de lo habitual, a veces estamos sin agua por algunas horas. Por favor, consulten antes de reserar.

Superhost
A scenic view of rolling hills under a colorful sky at sunset. Shades of orange, pink, and purple blend, creating a vibrant horizon. Lush trees are scattered across the landscape, adding a touch of greenery to the terrain.
Cottage in Olá
4.85 out of 5 average rating, 26 reviews

Country House in Olá, rivers, waterfalls, Los Picachos

Finca La Terapia lives up to its name, it is located among the mountains of the picturesque village of Olá de Penonomé, where you can disconnect from the busy day to day of the city. It has 42 private hectares to explore nature. The Olá district is characterized by having the most beautiful natural landscapes, among which we can mention Los Chorros de Olá, Chorros las Mesitas, Cerros los Picachos, Rio San Antonio, Balneario Brujas, among others, just a few minutes from the property.

Guest favourite
Home in Canto del Llano
4.89 out of 5 average rating, 18 reviews

Peaceful home w/ spacious living & office area

Spacious and peaceful home in a safe area of Santiago. 4 bedrooms (ideal for families and groups), bright living-dining area and large kitchen to share with family or friends, plus a private office for working comfortably. High-speed Wi-Fi, air conditioning and fans in all rooms, fully equipped kitchen, washer/dryer, and safe for valuables. Self check-in with smart lock, parking for several cars, and a coffee station with board games and karaoke.

Superhost
A large lagoon-style pool is visible, surrounded by palm trees and well-kept gardens. The expansive water reflects the blue sky and clouds, with several lounge chairs positioned along the poolside for relaxation.
Apartment in Playa Blanca-Farrallon (Distrito de Antón)
4.86 out of 5 average rating, 165 reviews

Playa Blanca-Spacious waterfront paradise

Conveniently located at 120 km from Panama City in Playa Blanca. Tastefully equipped 88 m2, one bedroom apartment offering more comfort than nearby hotels. Confy bed, lovely terrasse, good bathroom, fully equipped kitchen. The best view to the giant pool. Next to the sport center. Air conditioning, WIFI, cable TV included. Suitable for max. 4 persons. Access to giga salted pool also included it means that you can use the big pool in two parts.

Top guest favourite
An aerial view captures a scenic community surrounded by lush greenery and waterways. Residential buildings with terracotta rooftops are positioned near a serene lake and well-maintained gardens. The coastline is visible in the distance, providing a sense of tranquility to the landscape.
Apartment in El Chirú
4.98 out of 5 average rating, 143 reviews

Lagoon, Buenaventura

A spacious and quiet place in Buenaventura with capacity for (9) people, where you can enjoy a barbecue on its large terrace and its beautiful lake view. At 190 square meters, this beautiful apartment has: - Three spacious bedrooms. - 3 full bathrooms - Full Kitchen - A living room. -Dining Room - Terrace with barbecue grill, fan, chairs and outdoor armchairs. - A laundry area. - Two (2) parking spaces. - Area for bicycles or motorcycles.

Guest favourite
A terrace space is defined by outdoor seating arranged around a table. Lush greenery frames the scene, with soft sunlight illuminating the horizon where the sun rises over a tranquil landscape.
Flat in Rio Hato
4.93 out of 5 average rating, 143 reviews

Amazing! A paradise 5 minutes away from the sea

Discover our charming apartment just 5 minutes from the beach, where every morning will give you a spectacular view. Wake up to the beauty of a beautiful sunrise from the comfort of your room. Enjoy tranquility and serenity as you gaze at the warm colors painting the sky over the sea. Our apartment has been designed with you and your family in mind. Enjoy a cozy and functional space to create unforgettable memories.

Guest favourite
A cozy sleeping area features a spacious bed with neutral bedding. Soft lighting is provided by bedside lamps, and a ceiling fixture adds warmth. Two framed art pieces adorn the walls, offering a subtle contrast to the light decor.
Tiny home in Penonome
4.84 out of 5 average rating, 63 reviews

Fenced and Pet-Friendly Cottage in Penonomé

Cozy private cottage, fully fenced — perfect for relaxing, remote work, or traveling with your pet. Enjoy the garden surrounded by greenery, rest in the covered hammocks, or do some birdwatching. Equipped kitchen, air conditioning, high-speed WiFi, and secure on-site parking. Just minutes from the Interamerican Highway, with easy access to cafés, shops, and more. Ideal for a peaceful getaway or productive stay.

Guest favourite
Farm stay in Santa Fe
4.9 out of 5 average rating, 309 reviews

Cabaña del Sol en Finca Namuiki by the River

Spectacular contemporary style villa surrounded by local flowers and woods. The villas design enhances the relationship with the outside environment with panoramic windows which are found in the dining room and kitchen, this offers an awesome view of the mountains and green flora. The villa is located in a organic quiet farm, with abundant vegetation and great presence of birds.

Top guest favourite
A comfortable porch area features two colorful hammocks suspended from the walls. The polished tile flooring reflects soft light, and a pair of large wooden doors stands closed in the background. A vehicle is parked nearby, adding to the casual ambiance.
Home in Penonome
4.93 out of 5 average rating, 134 reviews

Comfortable, fenced and safe house.

Enjoy the simplicity of this spacious, quiet and centrally located place at Casa las Hamacas. You can enjoy the pleasant Penonomeño climate. A place close to everything, shopping malls, schools, hospital, mountains, rivers and beaches. Both rooms feature A/C to ensure your rest. A few minutes away from the Pan-American Highway.

Top guest favourite
A bright bedroom is displayed, featuring a spacious bed covered with a textured white blanket. A television is mounted on the wall opposite the bed. Natural light floods through large windows, accompanied by sheer curtains. A cozy orange chair and potted plant add a touch of warmth.
Tiny home in Playa El Jobo
4.96 out of 5 average rating, 27 reviews

Little home near to the beach -Las Tablas

10 min drive- Las Tablas Get away from it all when you stay under the stars. A room very close to the sea, with an open kitchen that will allow you to disconnect and enjoy the view and nature in Las Tablas. You can plan to visit nearby beaches or take a walk through Pedasí, 30 minutes from Las Tablas.

Top guest favourite
Home in La Villa de los Santos
4.94 out of 5 average rating, 106 reviews

Spacious house in Villa de los Santos

Comfortable family accommodation in La Villa de Los Santos, with Wi-Fi, A/C, equipped kitchen, patio and parking. Located near supermarkets and plazas. Only 15 minutes from El Rompió and Monagre, 45 minutes from Isla Iguana and 1h 30 minutes from Playa Venao.

Popular amenities for Santa María holiday rentals

  1. Airbnb
  2. Panama
  3. Herrera
  4. Santa María