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Holiday rentals in Santa María

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Top-rated holiday rentals in Santa María

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Superhost
Cottage in Playa El Jobo
4.76 out of 5 average rating, 120 reviews

Disfruta una Casa de Playa frente al mar, patio

Playa El Jobo is a magical place, special for connecting with nature and resting. It is oceanfront at a height of 9 meters, which allows you to receive the cool sea breeze. The property has a wooden house with a first floor and an upper floor. On the ground floor you will find the kitchen, two full bathrooms, two outdoor showers and a covered space with hammocks. Upstairs there is a large balcony with hammocks, two bedrooms, a living area and two bathrooms. There is good lighting, natural ventilation and A/C

Top guest favourite
The living area features large glass doors that invite natural light and views of the garden. Indoor plants enhance the space, and a cozy seating arrangement includes a sofa and eclectic chairs. A workspace with a desk and lamp is positioned to the side.
Guest house in El Valle de Antón
4.99 out of 5 average rating, 116 reviews

Spacious Casita with Bamboo View

Walk 20 minutes to the artisan mercado and restaurants on Ruta 71. Cerro Cara Iguana trailhead is walking distance from the casita. High insulated ceilings and 2 ceiling fans for comfort. Private hammock patio for an afternoon nap. Washer/dryer in the casita. Hot water throughout. Kitchen has a 2 burner cooktop, countertop oven, microwave, instant pot, electric skillet, blender and coffee maker. 2 Internet providers and a small workspace available. * No television set * Non smoking property

Top guest favourite
Inside the dome, a cozy sleeping area features a queen-sized bed with patterned bedding. A compact dining space with two chairs and a table sits by large windows, offering views of the surrounding greenery. Soft lighting is provided by a modern ceiling fixture.
Dome in Churuquita Grande
5 out of 5 average rating, 44 reviews

Aqeel Jungle River Dome

Discover the perfect escape at our cozy 215 sq. ft. Luxury glamping dome, nestled in the heart of a serene jungle and just steps away from the river. This unique retreat offers a balance of modern comforts and natural tranquility: Modern Comforts: Stay cool with air conditioning, and take advantage of a private washroom and a convenient kitchenette for your cooking needs. Outdoor BBQ: Fire up the barbecue outside and dine al fresco while soaking in the sights and sounds of the river.

Superhost
A scenic view of rolling hills under a colorful sky at sunset. Shades of orange, pink, and purple blend, creating a vibrant horizon. Lush trees are scattered across the landscape, adding a touch of greenery to the terrain.
Cottage in Olá
4.79 out of 5 average rating, 28 reviews

Country House in Olá, rivers, waterfalls, Los Picachos

Finca La Terapia lives up to its name, it is located among the mountains of the picturesque village of Olá de Penonomé, where you can disconnect from the busy day to day of the city. It has 42 private hectares to explore nature. The Olá district is characterized by having the most beautiful natural landscapes, among which we can mention Los Chorros de Olá, Chorros las Mesitas, Cerros los Picachos, Rio San Antonio, Balneario Brujas, among others, just a few minutes from the property.

Guest favourite
The exterior of the house features a charming design with a red-roofed upper level and a welcoming terrace. A small pool is visible in the foreground, surrounded by lush greenery and natural rock formations. Cloudy skies create a serene atmosphere, enhancing the tranquil setting.
Home in El Nancito
4.95 out of 5 average rating, 37 reviews

Mountain Retreat: Peaceful & Private Escape

Escape to tranquility in our beautiful rural retreat near Laguna de San Carlos, Panama. Nestled on a private hectare of lush land, this cozy two-bedroom, two-bath house boasts an open terrace with breathtaking views of the San Carlos mountains. Whether basking in summer sun or enveloped in clouds during the rainy season, you’ll find peace and beauty here. Just a 30-minute drive to Coronado and the stunning beaches of Panama Oeste, it’s the perfect sanctuary for your getaway.

Superhost
Home in Santiago
4.83 out of 5 average rating, 24 reviews

Casa a minutos de Santiago, U Latina, HospChichoF.

Spacious, comfortable and fully equipped house in a strategic location in Santiago. Perfect for all types of guests: families, business travelers, students, people coming to medical appointments or those looking for a quiet and accessible space. The house is located very close to Dr. Chicho Fábrega Hospital, Clínica Norte, U.Latina, Oxford School, shops, supermarkets, pharmacy, restaurants, and minutes from downtown Santiago. A safe place for short and long stays.

Guest favourite
A small pool sits within a wooden deck area, surrounded by lush greenery. Steps lead from the deck to the pool, where a gentle waterfall feature adds a soothing element. Lounge chairs are positioned nearby for relaxation in a tranquil setting.
Guest house in Panamá Oeste
4.83 out of 5 average rating, 134 reviews

Mountain cabin with private pool

Enjoy peace and nature in this cozy and equipped cabin, perfect for disconnecting and relaxing. Surrounded by forests and spectacular views, here you can breathe fresh air and gaze at the stars. ✔️ Ideal for couples, families or adventurers. ✔️ Trails, rivers and viewpoints nearby. ✔️ Comfortable and equipped spaces for your comfort. - Sleeps 4 people. - Possibility of having 1 double bed and 2 single beds or 4 single beds. - Discount for two nights or more.

Guest favourite
A bright bedroom is displayed, featuring a spacious bed covered with a textured white blanket. A television is mounted on the wall opposite the bed. Natural light floods through large windows, accompanied by sheer curtains. A cozy orange chair and potted plant add a touch of warmth.
Tiny home in Playa El Jobo
4.95 out of 5 average rating, 41 reviews

Private Beach Studio · Sunset & Nature Views

Designed for comfort, functionality, and a welcoming atmosphere: • Comfortable bed for a truly restful sleep • Air conditioning • Wi-Fi • Kitchen • 2 Bathrooms • Parking Perfect for short stays or longer breaks. Wake up at your leisure, enjoy a relaxing coffee, stroll to the beach, or simply unwind in this space. This place is ideal for: • Romantic getaways • Personal retreats • “Work from the beach” • Escaping the hustle and bustle of the city

Guest favourite
Home in Canto del Llano
4.88 out of 5 average rating, 32 reviews

Peaceful home w/ spacious living & office area

Spacious and peaceful home in a safe area of Santiago. 4 bedrooms (ideal for families and groups), bright living-dining area and large kitchen to share with family or friends, plus a private office for working comfortably. High-speed Wi-Fi, air conditioning and fans in all rooms, fully equipped kitchen, washer/dryer, and safe for valuables. Self check-in with smart lock, parking for several cars, and a coffee station with board games and karaoke.

Top guest favourite
Camper van/Motorhome in El Valle de Antón
4.99 out of 5 average rating, 255 reviews

Armadillo Shelter & Garden Valle de Anton

It is a unique and special accommodation that we have designed for you to experience the Anton Valley in a more conscious and natural way. It's a remodeled RV or trailer, to make it cozy>functional and comfortable>tiny house style. The space has a small and complete kitchen, hot water, Wi-Fi, coffee and tea. It is surrounded by a nice garden. With a separate entrance and an area to park the car. Ideal for 1-2 people.

Top guest favourite
A covered patio area displays a mix of seating options, including two wicker chairs and a small glass-top table surrounded by greenery. A hammock hangs gracefully in the foreground, adding a touch of comfort to this relaxed outdoor setting.
Cottage in El Valle de Antón
4.99 out of 5 average rating, 156 reviews

Casa Campestre Los Macos, El Valle de Anton

🏡 Welcome to Casa Campestre Los Macos, a cozy retreat located in the green heart of El Valle de Antón, inside an extinct volcanic crater, the largest inhabited in the world. It is an experience of total rest, in a safe and quiet area, ideal for lovers of nature, silence and fresh air. You'll wake up to birdsong, enjoy a cup of coffee in the garden, and spend family evenings in a fully equipped house.

Guest favourite
A welcoming porch area is furnished with comfortable seating and vibrant hammocks, surrounded by lush greenery and flowering plants. The structure is set against a backdrop of a clear blue sky, with sunlit grass creating an inviting outdoor space.
Home in El Valle de Antón
4.91 out of 5 average rating, 58 reviews

La Florecita - Country house in Valle de Antón

Cozy getaway in the heart of the Anton Valley Enjoy an unforgettable stay in our warm and cozy house, ideal for families and groups of friends. Located in the center of the Anton Valley, you'll be minutes away from markets, restaurants, and major natural attractions. Our house combines comfort and charm, with spacious spaces perfect for relaxing and enjoying the cool mountain climate.

Popular amenities for Santa María holiday rentals

  1. Airbnb
  2. Panama
  3. Herrera
  4. Santa María