
House holiday rentals in Santo Domingo
Find and book unique houses on Airbnb
Top-rated house rentals in Santo Domingo
Guests agree: these houses are highly rated for location, cleanliness and more.

Casa Serena: cozy, modern, spacious and peaceful
Welcome to Casa Serena! A cozy, modern, and spacious house that exudes tranquility... perfect for trips with family or friends seeking a peaceful retreat. The ideal home for those looking to stay in a central area of Santo Domingo while also enjoying the benefits of a low-density residential neighborhood. With easy access, minimal traffic, high safety standards, serene surroundings, friendly neighbors, and a sense of peace, Casa Serena in the La Castellana urbanization is the perfect choice.

Casa Grullon - Loft. Comfort & ancient beauty meet
Perfect, lovely & charming loft to explore La Zona. Transport yourself to another era staying at Casa Grullon Loft (1 master bedroom, 1 open bedroom, 1 bathroom) dating back to the 1700s, offers a unique chance to experience colonial charm without sacrificing modern conveniences (like air-conditioning). Stay here and discover La Zona just by walking! everything is within walking distance (top restaurants are just 1 min away!), making the location perfect to explore the best of Santo Domingo.

casa bella 3 camas 1 king +2 twin airport 15min.
Relájate en este espacio tranquilo,elegante y seguro aeropuerto (15 minutos) playas ,calles principales Supermercados cerca (zona súper tranquila segura y muy confortable ) 1–incluimos servicio de lavado y secado 2–wifi 3–Tv Smart 55 sala y 65 hab principal 4–puerta principal inteligente con clave 5–muebles en leather 6– cama principal king size 7–aire acondicionado en la principal 8–parqueo techado y cerrado 9–inversor de Luz 24 horas incluido Soy súper atento con mis huéspedes

New - 3 Bd House Zona Colonial + Private Rooftop
🌴🥥 Welcome to the perfect oasis in the Dominican Republic. We are so happy to host you ! We are centrally located in La Zona Colonial, the historic central neighborhood of the Dominican Republic's capital, Santo Domingo. It is the oldest continuously inhabited European-established settlement in the Americas. We are steps away from restaurants, night life, bars, museums and landmarks. Casa Altagracia is an eclectic, unique and curated house welcoming families, couples and friends.

Stunning villa in Zona Colonial
Casa Republic – Historic Charm, Modern Luxury Tucked away in Santo Domingo’s iconic Zona Colonial, Casa Republic is a 4-suite architectural gem where colonial heritage meets contemporary design. Cool off in your private pool, unwind on the rooftop terrace, or relax in elegant indoor-outdoor spaces crafted for comfort and style. With room for up to 8 guests, this one-of-a-kind home offers a refined retreat in the charm of the old city.

Cozy, central and well-equipped place
We are located in a central and quiet part of the city, with access to 27 de Febrero, Máximo Gómez, and Jhon F. Kennedy avenues. Nearby are the Ibero-American University (Uníbe), Zambil shopping center, Banco Popular Dominicano Tower, as well as pharmacies and health centers. The apartment is located on the first floor, with independent access, parking, and an electric gate. It has a cable system, high-speed WiFi, and an inverter.

La Casita de Gazcue Bright C Suite
This simple but charming accommodation offers you a relaxing experience in a privileged location: just a 12-minute walk from the historic Colonial Zone and three blocks from the iconic Malecón, where you can enjoy ocean views, restaurants, and nightlife. Ideal for relaxing without going far, our space combines serenity with quick access to the main tourist, cultural and gastronomic attractions. Your comfort is our priority.

Charming Old City Corner House
This charming 2 bedroom corner house is located in the walled colonial city of Santo Domingo. It’s only a few steps away from historical attractions, museums, restaurants, coffee shops, bars, souvenir shops, bakeries, supermarket and lovely squares. The beautiful covered terrace, overlooking the rooftops of the old town with living area, hammock and BBQ is perfect for a relaxing afternoon or evening.

Cozy & Beautiful City Center House with Jacuzzi
The House is located in " El Cacique", one of the safest areas in the city, with access to Malecón ( Caribbean Sea), supermarket and clinics 5 minutes walk, access to Mirador Sur park, and 15-20 minutes from the most prestigious shopping centers in the city. Located approximately 40 minutes from the airport and 14 minutes from Zona Colonial.

Beautiful City Center House [Private Jacuzzi]
Cozy home in the National District, located in a quiet area near the Malecón. In our home, you can relax in the jacuzzi during the day and enjoy the evenings with a delicious barbecue in the private patio. Remember to the Read the House Rules. Thank you! (at the bottom of the listing).

Gorgeous Colonial House near Cafes and Bars
Make morning espresso in a bright, colonial-style kitchen with exposed brick archways and vintage cobalt tile floors. Swing in a hanging chair on a rooftop terrace with spectacular views of the historical district, then cool off in the plunge pool of a lush, totally private courtyard.

Simply beautiful
This unique place has a style all its own.
Popular amenities for house rentals in Santo Domingo
House rentals with a pool

Cheerful 4 bedroom home with pool and parking

House for groups with a pool SDE

Bonita villa RD

Colonial Oasis

Villa oasis

Experience Ultimate Comfort | 4BR Home

"Villa M & M Dream Getaway and Total Relaxation"

Family Villa with Pool
Weekly house rentals

Beautiful house near Las Americas Airport

villa yaya

Luxury, Classy Private House In Santo Domingo

Sweet home, 3 A/C, 3 Parking spaces. Av. Jacobo Mujluta

Shulywow Santo Domingo West Luxury Comfort Secure

Moderno apartamento a minutos del aeropuerto

Sweet 🏡 home

“Your home away from home”
Private house rentals

Your 2BR House + Terrace in the Colonial Zone

Villa Luxury: your exclusive paradise

House with Jacuzzi in Zona Colonial

Entire house for rent, private, Picuzzi

Twin Apartments • Pool + Central

Luxury 5BR Villa Large Pool Near Airport & Beach

Luxurious home

House with heated pool and BBQ
When is the best time to visit Santo Domingo?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sept | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | $64 SGD | $64 SGD | $64 SGD | $64 SGD | $64 SGD | $64 SGD | $64 SGD | $64 SGD | $64 SGD | $63 SGD | $64 SGD | $63 SGD |
| Avg. temp | 26°C | 26°C | 26°C | 27°C | 27°C | 28°C | 28°C | 28°C | 28°C | 28°C | 27°C | 26°C |
Quick stats about house rentals in Santo Domingo

Total holiday rentals
Explore 490 holiday rentals in Santo Domingo

Nightly prices starting at
Santo Domingo holiday rentals start at $13 SGD per night before taxes and fees

Verified guest reviews
Over 13,190 verified reviews to help you choose

Family-friendly holiday rentals
190 properties offer extra space & child-friendly amenities

Pet-friendly holiday rentals
Find 120 rentals that welcome pets

Holiday rentals with a pool
100 properties feature pools

Rentals with dedicated workspaces
180 properties have a dedicated workspace

Wifi availability
460 of Santo Domingo holiday rentals include wifi access

Popular amenities for guests
Guests love Kitchen, Wifi and Pool across Santo Domingo rentals

4.7 Average rating
Santo Domingo stays receive an average rating of 4.7 out of 5 from guests
Destinations to explore
- Punta Cana Holiday rentals
- San Juan Holiday rentals
- Las Terrenas Holiday rentals
- Santiago De Los Caballeros Holiday rentals
- Santo Domingo Este Holiday rentals
- Puerto Plata Holiday rentals
- Sosúa Holiday rentals
- Bayahibe Holiday rentals
- Cabarete Holiday rentals
- La Romana Holiday rentals
- Carolina Holiday rentals
- Juan Dolio Holiday rentals
- Rentals with lake access Santo Domingo
- Rentals with a washing machine and dryer Santo Domingo
- Rentals with a sauna Santo Domingo
- Rentals with a hot tub Santo Domingo
- Rentals with outdoor seating Santo Domingo
- Rentals with beach access Santo Domingo
- Mansion rentals Santo Domingo
- Holiday home rentals Santo Domingo
- Apartment rentals Santo Domingo
- Villa rentals Santo Domingo
- Loft rentals Santo Domingo
- Beachfront rentals Santo Domingo
- Rentals with a patio Santo Domingo
- Smoking-friendly rentals Santo Domingo
- Rentals with a fireplace Santo Domingo
- Rentals with breakfast Santo Domingo
- Rentals with an EV charger Santo Domingo
- Pet-friendly rentals Santo Domingo
- Rentals with a cinema Santo Domingo
- Family-friendly rentals Santo Domingo
- Guest house rentals Santo Domingo
- Aparthotel rentals Santo Domingo
- Flat rentals Santo Domingo
- Serviced apartment rentals Santo Domingo
- Ski-in/ski-out rentals Santo Domingo
- Rentals with pools Santo Domingo
- Boutique hotels Santo Domingo
- Fitness-friendly rentals Santo Domingo
- Rentals with an accessible-height bed Santo Domingo
- Hotel rooms Santo Domingo
- Rentals with a firepit Santo Domingo
- Waterfront rentals Santo Domingo
- Private suite rentals Santo Domingo
- Bed and breakfasts Santo Domingo
- House rentals Distrito Nacional
- House rentals Dominican Republic
- Playa Nueva Romana
- Ciudad Juan Bosch
- Playa Hemingway
- Metro Country Club
- Playa Guayacanes
- Malecón
- National Museum of Natural History
- Blue Mall
- Teatro Nacional Eduardo Brito
- Downtown Center
- Megacentro
- Zona Colonial
- Parque Iberoamerica
- Agora Mall
- Galería 360
- Cathedral of Santa María la Menor
- Dr. Rafael Ma. Moscoso National Botanical Garden
- Bella Vista Mall
- Playa Caribe
- Columbus Park
- Casa De Teatro
- The 3 Eyes National Park
- Casa Adefra
- Plaza De La Cultura
- Things to do Santo Domingo
- Nature and outdoors Santo Domingo
- Food and drink Santo Domingo
- Entertainment Santo Domingo
- Things to do Distrito Nacional
- Nature and outdoors Distrito Nacional
- Food and drink Distrito Nacional
- Things to do Dominican Republic
- Entertainment Dominican Republic
- Sports activities Dominican Republic
- Sightseeing Dominican Republic
- Tours Dominican Republic
- Nature and outdoors Dominican Republic
- Food and drink Dominican Republic
- Art and culture Dominican Republic





