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House holiday rentals in Santo Domingo

Find and book unique houses on Airbnb

Top-rated house rentals in Santo Domingo

Guests agree: these houses are highly rated for location, cleanliness and more.

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Top guest favourite
A spacious living area features a light-colored sofa adorned with decorative pillows. A coffee table with floral arrangements complements two blue accent chairs nearby. Large windows allow natural light to fill the room, enhancing the bright, airy atmosphere.
Home in Los Prados
4.99 out of 5 average rating, 136 reviews

Casa Serena: cozy, modern, spacious and peaceful

Welcome to Casa Serena! A cozy, modern, and spacious house that exudes tranquility... perfect for trips with family or friends seeking a peaceful retreat. The ideal home for those looking to stay in a central area of Santo Domingo while also enjoying the benefits of a low-density residential neighborhood. With easy access, minimal traffic, high safety standards, serene surroundings, friendly neighbors, and a sense of peace, Casa Serena in the La Castellana urbanization is the perfect choice.

Guest favourite
A modern living area is presented with white leather seating and a glass coffee table. Accent lights illuminate built-in shelving displaying decorative items. A fan and a television are positioned within the space, while dark curtains frame large windows.
Home in Los Frailes
4.88 out of 5 average rating, 260 reviews

casa bella 3 camas 1 king +2 twin airport 15min.

Relájate en este espacio tranquilo,elegante y seguro aeropuerto (15 minutos) playas ,calles principales Supermercados cerca (zona súper tranquila segura y muy confortable ) 1–incluimos servicio de lavado y secado 2–wifi 3–Tv Smart 55 sala y 65 hab principal 4–puerta principal inteligente con clave 5–muebles en leather 6– cama principal king size 7–aire acondicionado en la principal 8–parqueo techado y cerrado 9–inversor de Luz 24 horas incluido Soy súper atento con mis huéspedes

Guest favourite
A welcoming living area features a comfortable wooden sofa adorned with green cushions, accompanied by two wooden chairs. A round wooden coffee table is centered on a patterned blue and white rug, while a potted plant adds a touch of greenery near a window.
Home in Ciudad Colonial
4.85 out of 5 average rating, 123 reviews

New - 3 Bd House Zona Colonial + Private Rooftop

🌴🥥 Welcome to the perfect oasis in the Dominican Republic. We are so happy to host you ! We are centrally located in La Zona Colonial, the historic central neighborhood of the Dominican Republic's capital, Santo Domingo. It is the oldest continuously inhabited European-established settlement in the Americas. We are steps away from restaurants, night life, bars, museums and landmarks. Casa Altagracia is an eclectic, unique and curated house welcoming families, couples and friends.

Top guest favourite
A bright and airy entrance leads to a serene outdoor area with a pool. The space is framed by modern glass walls, showcasing inviting seating and greenery. Natural light filters through, enhancing the layout that connects indoor and outdoor living.
Home in Ciudad Colonial
5 out of 5 average rating, 51 reviews

Stunning villa in Zona Colonial

Casa Republic – Historic Charm, Modern Luxury Tucked away in Santo Domingo’s iconic Zona Colonial, Casa Republic is a 4-suite architectural gem where colonial heritage meets contemporary design. Cool off in your private pool, unwind on the rooftop terrace, or relax in elegant indoor-outdoor spaces crafted for comfort and style. With room for up to 8 guests, this one-of-a-kind home offers a refined retreat in the charm of the old city.

Guest favourite
The living area features a light blue sofa paired with a small neutral-toned coffee table. A colorful piece of wall art hangs above the sofa, and a dining table is visible in the corner. A ceiling fan and green curtains enhance the space, while natural light enters from a nearby window.
Home in Santo Domingo
4.95 out of 5 average rating, 164 reviews

Cozy, central and well-equipped place

We are located in a central and quiet part of the city, with access to 27 de Febrero, Máximo Gómez, and Jhon F. Kennedy avenues. Nearby are the Ibero-American University (Uníbe), Zambil shopping center, Banco Popular Dominicano Tower, as well as pharmacies and health centers. The apartment is located on the first floor, with independent access, parking, and an electric gate. It has a cable system, high-speed WiFi, and an inverter.

Guest favourite
Home in Santo Domingo
4.83 out of 5 average rating, 183 reviews

La Casita de Gazcue Bright C Suite

This simple but charming accommodation offers you a relaxing experience in a privileged location: just a 12-minute walk from the historic Colonial Zone and three blocks from the iconic Malecón, where you can enjoy ocean views, restaurants, and nightlife. Ideal for relaxing without going far, our space combines serenity with quick access to the main tourist, cultural and gastronomic attractions. Your comfort is our priority.

Top guest favourite
A covered terrace features a wooden floor, surrounded by potted plants. Four chairs with colorful cushions face a wooden table. A hammock and a cozy blue chair are positioned nearby, with an open view of the rooftops in the background.
Home in Ciudad Colonial
4.96 out of 5 average rating, 113 reviews

Charming Old City Corner House

This charming 2 bedroom corner house is located in the walled colonial city of Santo Domingo. It’s only a few steps away from historical attractions, museums, restaurants, coffee shops, bars, souvenir shops, bakeries, supermarket and lovely squares. The beautiful covered terrace, overlooking the rooftops of the old town with living area, hammock and BBQ is perfect for a relaxing afternoon or evening.

Superhost
An infinity pool extends towards the horizon, creating a seamless view of the ocean. Palm trees frame the area, providing a tropical ambiance. The clear water reflects the blue sky, enhancing the tranquil setting.
Home in Jardines del Sur
4.86 out of 5 average rating, 7 reviews

House in the city with an oceanfront swimming pool

Oceanfront house in a private residential development. Unique location because it is in the city (west). Main room on the second floor, open to the sea. Kitchen in the main room. 4 bedrooms with one facing the sea and 3 full bathrooms in total in the house and one downstairs for visitors. Gym. Billiard room. Pool and Jacuzzi. Large private garage with electric door.

Guest favourite
A modern living area features two armchairs in rose color opposite a sleek marble coffee table. A television is mounted on the wall, and light filters through sheer curtains, illuminating the space. Decorative elements include a vase of flowers on the side table.
Home in El Cacique
4.94 out of 5 average rating, 125 reviews

Cozy & Beautiful City Center House with Jacuzzi

The House is located in " El Cacique", one of the safest areas in the city, with access to Malecón ( Caribbean Sea), supermarket and clinics 5 minutes walk, access to Mirador Sur park, and 15-20 minutes from the most prestigious shopping centers in the city. Located approximately 40 minutes from the airport and 14 minutes from Zona Colonial.

Guest favourite
A private outdoor space features a sparkling pool surrounded by blue mosaic tiles. A shaded gazebo with wooden beams offers comfortable seating, ideal for relaxation. Lush tropical plants frame the area, enhancing the overall tranquility of the setting.
Home in El Cacique
4.85 out of 5 average rating, 108 reviews

Beautiful City Center House [Private Jacuzzi]

Cozy home in the National District, located in a quiet area near the Malecón. In our home, you can relax in the jacuzzi during the day and enjoy the evenings with a delicious barbecue in the private patio. Remember to the Read the House Rules. Thank you! (at the bottom of the listing).

Guest favourite
An inviting rooftop terrace features a hanging chair and comfortable cushioned seating. A wooden coffee table stands at the center. Lush greenery provides a natural backdrop with trees visible, and the sky showcases soft clouds, creating a serene outdoor atmosphere.
Home in Ciudad Colonial
4.94 out of 5 average rating, 447 reviews

Gorgeous Colonial House near Cafes and Bars

Make morning espresso in a bright, colonial-style kitchen with exposed brick archways and vintage cobalt tile floors. Swing in a hanging chair on a rooftop terrace with spectacular views of the historical district, then cool off in the plunge pool of a lush, totally private courtyard.

Guest favourite
A modern living area is displayed with a sleek wooden coffee table topped with decorative bowls. A large television mounted on the wall features a nature scene. Floor-to-ceiling windows offer city views, while a cozy couch is positioned nearby.
Home in Ensanche Quiqueya
4.91 out of 5 average rating, 64 reviews

Simply beautiful

This unique place has a style all its own.

Popular amenities for house rentals in Santo Domingo

When is the best time to visit Santo Domingo?

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Quick stats about house rentals in Santo Domingo

  • Total holiday rentals

    Explore 490 holiday rentals in Santo Domingo

  • Nightly prices starting at

    Santo Domingo holiday rentals start at $13 SGD per night before taxes and fees

  • Verified guest reviews

    Over 13,190 verified reviews to help you choose

  • Family-friendly holiday rentals

    190 properties offer extra space & child-friendly amenities

  • Pet-friendly holiday rentals

    Find 120 rentals that welcome pets

  • Holiday rentals with a pool

    100 properties feature pools

  • Rentals with dedicated workspaces

    180 properties have a dedicated workspace

  • Wifi availability

    460 of Santo Domingo holiday rentals include wifi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi and Pool across Santo Domingo rentals

  • 4.7 Average rating

    Santo Domingo stays receive an average rating of 4.7 out of 5 from guests

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