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House holiday rentals in Santo Domingo De Guzmán

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Top-rated house rentals in Santo Domingo De Guzmán

Guests agree: these houses are highly rated for location, cleanliness and more.

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Top guest favourite
Home in Los Prados
4.99 out of 5 average rating, 126 reviews

Casa Serena: cozy, modern, spacious and peaceful

Welcome to Casa Serena! A cozy, modern, and spacious house that exudes tranquility... perfect for trips with family or friends seeking a peaceful retreat. The ideal home for those looking to stay in a central area of Santo Domingo while also enjoying the benefits of a low-density residential neighborhood. With easy access, minimal traffic, high safety standards, serene surroundings, friendly neighbors, and a sense of peace, Casa Serena in the La Castellana urbanization is the perfect choice.

Guest favourite
Home in Ciudad Colonial
4.88 out of 5 average rating, 123 reviews

Colorful Caribbean house in the Zona Colonial

Enjoy a marvelous stay at this gorgeous, colorful and spacious home at the Zona Colonial. Light, airy rooms and amazing private outdoors create a unique caribbean flair. Relax in the tropical garden...refresh yourself with a dip into the tiny pool…dine under the stars or enjoy the amazing view of the San Francisco monastery ruins from the balcony. The famous Plaza de España is a few steps away and all the historical sites, museums, restaurants, cafés and bars are within easy walking distance.

Superhost
Home in Arenoso
4.82 out of 5 average rating, 95 reviews

Private Jacuzzi Apartment | Central Location

✨ Disfruta de una experiencia única en este alojamiento con estilo y comodidad ubicado en una zona céntrica y de fácil acceso a todo lo que necesitas. Perfecto tanto para viajes de placer como de trabajo, aqui tendrás todo lo que necesitas para sentirte como en casa. 🛏️ Habitación con aire acondicionado,TV, baño, cama cómoda para un descanso fresco y confortable. 🛋️ Sala con aire acondicionado. 🛁 Jacuzzi privado. 🍽️ Cocina totalmente equipada y comedor funcional. 🚗 1 parqueo gratuito.

Guest favourite
Home in Los Frailes
4.89 out of 5 average rating, 230 reviews

casa bella 3 camas 1 king + 2 twin airport 15min.

Relájate en este espacio tranquilo,elegante y seguro aeropuerto (15 minutos) playas ,calles principales Supermercados cerca (zona súper tranquila segura y muy confortable ) 1–incluimos servicio de lavado y secado 2–wifi 3–Tv Smart 55 sala y 65 hab principal 4–puerta principal inteligente con clave 5–muebles en leather 6– cama principal king size 7–aire acondicionado en la principal 8–parqueo techado y cerrado 9–inversor de Luz 24 horas incluido Soy súper atento con mis huéspedes

Guest favourite
Home in Los Frailes
4.83 out of 5 average rating, 24 reviews

'Casa de Papel' Luxurious VILLA

Discover the ultimate party getaway at Villa Fiesta Oasis! This luxurious 4-bedroom villa offers everything you need for an unforgettable stay: a sparkling pool, a relaxing jacuzzi, and ample space for entertaining. Located just minutes from the airport, convenience and comfort come together in this stunning retreat. Whether you're hosting a celebration or simply seeking a relaxing escape, House of Cards (Casa de Papel) is your perfect destination. Experience the best of Santo Domingo!

Guest favourite
Home in Ciudad Colonial
4.88 out of 5 average rating, 16 reviews

Luxury Morden house with Jacuzzi Zona Colonial.!

This unique place has a style all its own. This beautiful house, located in the colonial zone, will make you feel at home. It is a modern house, equipped with everything necessary for the comfort of the guests including a root top Jacuzzi, and social area with a beautiful view. Quiet zone. Near the port of San Souci, El Conde street, supermarkets and restaurants, museums, bus stops and other facilities. You will not want to leave. Also you have a courtesy drinks at @vidalocabar.

Guest favourite
Home in Gazcue
4.82 out of 5 average rating, 164 reviews

The Bright Gazcue Suit C Cottage

Este alojamiento sencillo pero encantador te ofrece una experiencia relajante en una ubicación privilegiada: a solo 12 minutos caminando de la histórica Zona Colonial y a tres cuadras del emblemático Malecón, donde podrás disfrutar de vistas al mar, restaurantes, y vida nocturna. Ideal para descansar sin alejarse, nuestro espacio combina serenidad con acceso rápido a los principales puntos turísticos, culturales y gastronómicos. Tu comodidad es nuestra prioridad.

Top guest favourite
Home in Ciudad Colonial
5 out of 5 average rating, 27 reviews

Stunning villa in Zona Colonial

Casa Republic – Historic Charm, Modern Luxury Tucked away in Santo Domingo’s iconic Zona Colonial, Casa Republic is a 4-suite architectural gem where colonial heritage meets contemporary design. Cool off in your private pool, unwind on the rooftop terrace, or relax in elegant indoor-outdoor spaces crafted for comfort and style. With room for up to 8 guests, this one-of-a-kind home offers a refined retreat in the charm of the old city.

Top guest favourite
Home in Santo Domingo
4.95 out of 5 average rating, 154 reviews

Cozy, central and well-equipped place

We are located in a central and quiet part of the city, with access to 27 de Febrero, Máximo Gómez, and Jhon F. Kennedy avenues. Nearby are the Ibero-American University (Uníbe), Zambil shopping center, Banco Popular Dominicano Tower, as well as pharmacies and health centers. The apartment is located on the first floor, with independent access, parking, and an electric gate. It has a cable system, high-speed WiFi, and an inverter.

Top guest favourite
Home in Ciudad Colonial
4.96 out of 5 average rating, 212 reviews

Cozy little house in the heart of the Colonial Zone

A cozy 2-bedroom house for 4 people, located in the heart of the Colonial Zone in Santo Domingo, within walking distance of all cultural and tourist attractions. It has 2 comfortable bedrooms and a study with a sofa bed; 2 bathrooms, a nice living room, large dining room, equipped kitchen and a beautiful inner courtyard. Wonderful for vacations and cultural trips, ideal for couples, families, friends, and business travelers.

Guest favourite
Home in Ciudad Colonial
4.97 out of 5 average rating, 30 reviews

Charming Colonial House!

Discover this beautiful renovated colonial house with a modern minimalist touch, located 2 minutes from Puerta del Conde and the historic Colonial City of Santo Domingo. Just steps from the Malecón, you'll be in a quiet area but close to restaurants, bars, beauty salons, spas, and supermarkets. Enjoy a comfortable stay in the heart of the city, combining history, modernity, and convenience. Perfect for exploring!

Top guest favourite
Home in Ciudad Colonial
4.95 out of 5 average rating, 109 reviews

Charming Old City Corner House

This charming 2 bedroom corner house is located in the walled colonial city of Santo Domingo. It’s only a few steps away from historical attractions, museums, restaurants, coffee shops, bars, souvenir shops, bakeries, supermarket and lovely squares. The beautiful covered terrace, overlooking the rooftops of the old town with living area, hammock and BBQ is perfect for a relaxing afternoon or evening.

Popular amenities for house rentals in Santo Domingo De Guzmán

Quick stats about house rentals in Santo Domingo De Guzmán

  • Total rentals

    470 properties

  • Nightly prices starting at

    $13 SGD before taxes and fees

  • Total number of reviews

    11K reviews

  • Family-friendly rentals

    200 properties are a good fit for families

  • Pet-friendly rentals

    120 properties allow pets

  • Rentals with a pool

    100 properties have a pool

Destinations to explore