Boutique hotels in South Carolina

Find and book unique boutique hotels on Airbnb

Top-rated boutique hotels in South Carolina

Guests agree: these boutique hotels are highly rated for location, cleanliness and more.

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Superhost
A well-appointed bedroom features a plush, spacious bed with crisp white linens and a decorative throw blanket. A modern bedside table holds fresh flowers. Light enters through sheer curtains, enhancing the tranquil atmosphere of the room.
Hotel room in North Charleston
4.82 out of 5 average rating, 666 reviews

The Starlight Motor Inn - King + Pool!

The Starlight Motor Inn is a historic mid-century motel in the heart of N. Charleston, SC! Family run since 1961, The Starlight was conceived as an affordable and accessible destination for locals and visitors alike. In 2022 the property was lovingly restored & reimagined as a 51 room oasis conveniently located on Rivers Avenue just minutes from downtown Charleston. The property is complete with a fabulous pool, full service bar The Burgundy Lounge with nightly live entertainment, & event space!

Hotel room in Hemingway
4.67 out of 5 average rating, 3 reviews

Garden of Eden

The Garden of Eden Room at Bella’s Boutique Hotel is a peaceful retreat that blends nature-inspired design with authentic historic charm. This thoughtfully designed room offers a calming atmosphere, perfect for guests looking to unwind in a space that feels both warm and unique. Only 3 rooms in the entire hotel retain these original sinks and tubs, making this bathroom a rare and special feature that adds old-world charm. One of the room’s standout features is its original exposed brick wall

Guest favourite
A spacious guest room features two plush queen beds with crisp white linens and decorative blue headboards. A wooden desk and chair are positioned against the wall, complemented by a microwave and refrigerator. Dual colors of the wall and warm lighting contribute to a relaxing ambiance.
Hotel room in Columbia
5 out of 5 average rating, 26 reviews

Trundle Double Queen

Husband and wife team owners Marcus and Rita dreamed of owning an independent boutique hotel in the heart of downtown Columbia with the freedom to craft a guest experience like no other. When that very opportunity presented itself in 2016, they dubbed it their unicorn opportunity because, to them, it was truly that. They believe that the unicorn is a fabulous beast conceived not out of human fear but as a beautiful creation of humankind’s creative, joyful, and ever-powerful imagination.

Superhost
Hotel room in Myrtle Beach
4.8 out of 5 average rating, 10 reviews

Modern Beachside Studio • Pool • Free Parking

The beach is 3 minutes away. You'll feel it the moment you arrive. Kick off your shoes, drop your bags, and let Myrtle Beach do the rest. Fin's Inn & Suites puts you steps from the sand - close enough to hear the waves, far enough to actually sleep in. Upgraded bedding, complimentary Starbucks coffee pods, and bottled water waiting at check-in - because vacation starts the moment you walk in. Cool off in the pool, recharge in the game lounge, and leave the car parked all week.

Superhost
Hotel room in North Charleston
4.91 out of 5 average rating, 11 reviews

Circulo • King Corner Suite • Prime Location

Welcome to Circulo's Corner Suite, creatively designed for comfort. Highlights include three additional window treatments that fill the oversized space with natural light, along with bespoke works from local artists and makers. Located in the heart of North Charleston’s Park Circle district, our boutique hotel blends artisan craftsmanship with modern comforts. *We are in our soft opening - Due to this, rates are discounted as we finish up details * Permit Number: LIC063515

Guest favourite
The room is furnished with a black metal bed frame supporting a spacious bed, flanked by two bedside lamps. A rustic bench sits at the foot of the bed. A vintage fireplace and an armoire are visible, along with a cozy seating area featuring light-colored chairs.
Hotel room in Charleston
4.94 out of 5 average rating, 105 reviews

SWEETGRASS room at Pinckney

Welcome the SWEETGRASS room. This historic INN boasts 5 charming rooms with exterior access at the heart of the market and stables.Please click our bio photo to view all rooms, rates & reviews. Enjoy a King bed, private bath, wifi, TV and a Fireplace in cooler months. Complimentary snacks, pastries and beverages. SWEETGRASS is located on the ground floor with access off the main piazza. Parking is available at reasonable rates in multiple lots within 2 blocks of the inn.

Superhost
A king bed with white bedding is centered in the room, flanked by two bedside lamps. A minimalist nightstand and a light wood headboard complement the space. Tropical-themed wallpaper features green leaves, and a small wall-mounted TV is visible. A coffee maker and mini fridge are arranged on a counter.
Hotel room in Folly Beach
4.79 out of 5 average rating, 61 reviews

Folliday Inn: The Torpedo: Room 22

Room 22- The Torpedo. This 2nd floor guest room has a private entry, a King-sized bed, mini fridge, microwave, free WIFI, & smart TV for up to 2 guests. The bathroom is outfitted with a tub & shower. Swim in the largest pool on Folly Beach! Beach access is only 1 block away. Great romantic escape! Must be 21 years+. Please note this unit comes with 1 on-site parking pass only. Community grill. NO smoking. Pet friendly for 1 dog with an additional $125 + tax fee.

Superhost
The serene beach scene captures a sunset over the coastline, with tall buildings lining the shore. The reflections of the structures are visible in the calm water, creating a harmonious blend of colors as day transitions into evening.
Hotel room in North Myrtle Beach

Spacious & Vibrant 1-BD Haven in North Myrtle

Take it easy at this unique and tranquil getaway. Discover this spacious & vibrant 1-bedroom haven in North Myrtle Beach! Perfectly blending coastal charm and modern comfort, this retreat features an open-concept living area with stylish decor, a fully equipped kitchen, and a cozy bedroom with a plush king bed. Enjoy ample natural light, a private balcony with scenic views, and access to resort-style amenities like pools, fitness centers, and easy beach access.

Guest favourite
Hotel room in Folly Beach
4.83 out of 5 average rating, 161 reviews

Tree House Room | Handcrafted Bed & Tropical Vibes

Inspired by the feeling of staying in a tropical treehouse, this unique room features a handcrafted full size bed built by the owners using locally sourced James Island trees. The room's Costa Rican-inspired design, open walk-in shower, and relaxed island atmosphere create a one-of-a-kind Folly Beach getaway. Guests enjoy shared access to the historic cottage, outdoor tiki bar porch, and complimentary daily breakfast.

Superhost
A comfortable sleeping area features a spacious bed adorned with crisp white linens and a decorative blue pillow. Flanking the bed are two modern nightstands, each topped with a lamp. A soft, neutral color palette is complemented by wooden accents.
Hotel room in Mount Pleasant
5 out of 5 average rating, 5 reviews

Shem Creek Inn, CREEK SIDE KING

Discover your dockside hideaway at the Shem Creek Inn, a hotel built on local traditions and a treat for visitors. Located in Mount Pleasant, SC, you’ll have relaxing accommodations across the harbor from Downtown Charleston. Your room charge will be paid prior to your arrival. The remaining balance of taxes (13%), destination fee ($2.26/night) and resort fee ($10/night) will be charged upon arrival.

Hotel room in Myrtle Beach
4.72 out of 5 average rating, 57 reviews

King One-Bedroom Suite at The Caretta

The King One-Bedroom Suite offers apartment-style comfort just steps from the beach. Featuring a separate king bedroom, a spacious living room with a queen sleeper sofa, and a full kitchen, this suite is designed for travelers seeking additional space and flexibility during their stay in Myrtle Beach. A great option for weekend escapes, longer stays, or small family vacations near the ocean.

Guest favourite
A spacious studio room features a King size bed with a light grey comforter, complemented by bedside tables with lamps. Colorful artwork is displayed on the white walls, and large windows offer views of the outside area, filtered by purple curtains.
Hotel room in Folly Beach
4.96 out of 5 average rating, 80 reviews

Boutique Vera Hotel King Room 302

The Studio room has a living area and King size bed in the same room. There is a full bathroom. This studio room is on the third floor. Dog friendly with a one-time fee of $125 per dog. Fee is added once your reservation is confirmed. PLEASE NOTE THE LOCATION OF THIS ROOM IS ON THE 3RD FLOOR AND IS IN THE MIX OF COMMERCIAL CENTER STREET ACTIVITY, YOU WILL HEAR THE NOISE

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