Holiday rentals in Mayo Lake

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Top-rated holiday rentals in Mayo Lake

Guests agree: these stays are highly rated for location, cleanliness and more.

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Top guest favourite
A modern cabin is set among trees, featuring a dark exterior with string lights accentuating the entrance. A gravel patio surrounds a fire pit with a stone border, and a picnic table is positioned nearby, creating a welcoming outdoor space for gatherings.
Cabin in Roxboro
4.95 out of 5 average rating, 21 reviews

Mayo Lake Cabin Fun Peaceful Retreat With Firepits

Moonlight Cabin is a modern waterfront home on Mayo Lake. The lake house and nature provides a secluded and peaceful stay while being minutes from shopping, winery, and dining options. This family friendly cabin is both fun and relaxing. Enjoy quiet mornings overlooking the water with a coffee, swim & play in water, spend evenings by the fire pits, and take in the serenity of nature. Indoors, relax with board games, movies, reading, and fast WiFi. Perfect for couples, families, or work escapes.

Guest favourite
A wooden dock extends over calm water, featuring a picnic table shaded by a large umbrella. A gentle slope leads to the dock, surrounded by a serene lake landscape and distant tree-covered hills under a partly cloudy sky.
Home in Clarksville
4.92 out of 5 average rating, 139 reviews

Kerr Lake Amazing Views, Private Dock, Quiet

Peaceful lakefront retreat: Private dock, table, and new solar-lit umbrella (7/28/25). Amenities include a new gas grill (7/28/25), paddleboard, canoe, kayak, cornhole, hammock, firepit, puzzles, books, and games. Enjoy a large deck with two tables and a screened porch with couch—perfect for morning coffee. The home features 3 bedrooms, a loft, 3 full baths, and a dedicated workspace. Ideal for families, friends, or fishing trips. Driveway fits 5 trucks with trailers; boat launch 2 miles away.

Top guest favourite
A fire pit area with several Adirondack chairs surrounds a central space. String lights illuminate the area, creating a cozy evening ambiance. The two-story home is visible in the background, featuring large windows and a spacious deck. Lush trees surround the setting.
Home in Roxboro
4.98 out of 5 average rating, 95 reviews

Private Lakefront Paradise - Paddleboards & Kayaks

*Dogs only allowed with approval from owner. Scroll down to read more.* Beautiful 3 bedroom, 3 bath home on Mayo Lake in Roxboro, NC. Incredible views of the lake. You rarely see anyone on our secluded cove. You can swim, fish, paddleboard, kayak or tie up your boat. House is only 5 minutes from the marina and comes with paddleboards and kayaks and has a fire pit. Large, open kitchen, family room/ entertainment room, ping pong table, and jetted tub. Close to hiking, fine dining, and VIR.

Top guest favourite
Cabin in Roxboro
4.88 out of 5 average rating, 192 reviews

Water Front Lake House!

Waterfront home on MAYO LAKE. 2 Bd, 1.5 bath fully furnished . Wi-fi, Smart TVs, Alexa, frig, stove washer/dryer, microwave. Queen-size bed, sleeper sofa and bunk bed. Wrap around porch w/ rocking chairs, swing and 2 picnic tables. Large yard for playing, just feet away from the water, and fire pit. Firewood not provided. Lots of fishing, single kayak, 2 person kayak, canoe and 2 paddle boats available. PERFECT FOR ANY SEASON LONG OR SHORT STAY. Located on Mayo Lake in Roxboro, NC

Superhost
A calm lake reflects a clear blue sky with scattered clouds. Lush greenery borders the water, creating a serene atmosphere. Lily pads are visible near the shore, adding to the natural beauty of the landscape.
Home in Roxboro
4.73 out of 5 average rating, 15 reviews

Lake House Hide Away

Experience a peaceful lakeside escape with this beautifully maintained and amenity-rich home steps from tranquil Mayo Lake. Whether you're visiting for fishing, hunting or simply to relax in nature, this Airbnb delivers! This 2 bedroom ,1 bath has a King size bed in one room & a queen in the other . The Kitchen is fully stocked & includes a waffle maker & coffee bar !Whether you want to roast s’mores at the fire pit , take a ride on the kayaks or just relax this is the place for you

Top guest favourite
Home in Roxboro
5 out of 5 average rating, 11 reviews

Glass House on the Lake

This midcentury modern retreat nestled in a relaxing cove features floor-to-ceiling glass walls allowing the outdoors in, beautiful exposed wood beams, hardwood floors, and a cozy concrete fireplace. Enjoy the screened porch with new comfortable seating, updated kitchen, and stunning lake views. The gentle slope to the private dock passes by numerous resting nooks. Convenient to the Triangle, Triad, and VIR, it’s the perfect getaway blend of relaxation and adventure.

Guest favourite
Home in Roxboro
4.9 out of 5 average rating, 145 reviews

Lakefront Oasis-HotTub | GameRoom | Kayaks | Dock

At Pointe Mayo Lake, discover a serene, rustic retreat by Mayo Lake. Enjoy amenities like kayaks & canoes, private dock, fishing rods, a grill, a hot tub, a game room, and a fire pit. Perfect for avid vacationers, couples, families, groups of professionals, and even your furry friends! We are Pet and Family Friendly! Love what you see but not ready to book? Click the ❤️ "Save" button on the top right to easily find us again and secure your getaway when you're ready!

Superhost
A serene lakeside view captures the early morning mist hovering over the calm water. Soft hues of orange and yellow reflect on the surface, while the silhouette of trees outlines the horizon. A wooden dock extends into the scene, inviting peaceful moments by the water.
Home in Prospect Hill
4.84 out of 5 average rating, 180 reviews

Lakefront Hygge: Dock|Marine Hammock|Screen Porch

Discover a peaceful haven on the water in Prospect Hill! This stylish Scandinavian Modern house boasts a private dock on a quiet reservoir, offering a serene escape. Enjoy the natural beauty and tranquility, while still being a short drive to Hillsborough, Chapel Hill, Durham, Raleigh, Greensboro, Charlotte and Danville. With a cozy, inviting interior, and abundant places to enjoy the outdoors, this waterfront property is the perfect place to "press pause".

Top guest favourite
A serene lake is observed from a wooden dock, with calm waters reflecting surrounding greenery and a clear sky. The shoreline is lined with trees, creating a tranquil atmosphere. Ripples gently disturb the water's surface, highlighting the lake's peaceful environment.
Home in Roxboro
4.98 out of 5 average rating, 110 reviews

Long’s Lakehouse

Relax with the whole family at this peaceful waterfront property. It is a 2 bedroom, 2 bathroom house with one king bed, one queen bed, and a pull out sofa! The kitchen is fully stocked with a coffee pot, utensils, pizza pan, crock pot, skillet, pots , pans, baking sheets, toaster, oven and microwave! Bedrooms and living room have smart tvs. WiFi available! Enjoy the kayaks, lots of fishing, grilling, and fire pit! There is something for here for everyone!

Top guest favourite
Home in Semora
5 out of 5 average rating, 15 reviews

Lake Front | Beautiful Views | Perfect Getaway

Come find a place of rest, relaxation and renewal here at Still Waters. A place that has been built by the hands of its owners, bringing peace to everyone that enters the home. This custom built home is situated just on the waters edge, with a dock and canoes available for use. This home is perfect for a couples get away, looking to recharge away from the hustle and bustle of our everyday lives. Roxboro is about 25 minutes away from the home.

Guest favourite
The log cabin is surrounded by lush greenery, with vibrant azaleas in full bloom occupying the foreground. A welcoming porch features bench seating, and large windows provide natural light. The sloped roof with gables adds architectural interest, set against a backdrop of trees.
Cabin in Roxboro
4.94 out of 5 average rating, 137 reviews

Majestic Lakefront Log Cabin in the NC High Plains

Cozy Log Cabin located on Lake Mayo just above Roxboro, North Carolina on Whispering Wolf Ranch. Easy access to a functional floating dock. Great for fishing, swimming, meditating, or to just enjoy nature. Paddle boards and Kayaks can be rented at nearby Mayo Lake Park. Can be used for a private romantic getaway or family retreat. Less than 5 miles from the events held at Lake Mayo Park. PARTIES OR EVENTS ARE NOT ALLOWED!

Guest favourite
A charming tiny cabin surrounded by trees showcases a spacious outdoor area featuring a fire pit with Adirondack chairs, a hot tub on the deck, and a sauna. The cabin's sleek design and wooden elements integrate seamlessly into the natural setting.
Tiny home in Hurdle Mills
4.95 out of 5 average rating, 140 reviews

The Tiny Cabin At Hurdle Mills - Sauna & Hot Tub

Welcome to our cozy Tiny home on 5 acres nestled in the beautiful town of Hurdle Mills, North Carolina. Surrounded by nature, our tiny cabin is the perfect getaway for those looking to unplug and enjoy the quiet of nature. Relax in the hot tub, build a cozy fire at the fire pit, enjoy the sauna and cold plunge with chiller combo to engage in hot-cold therapy and gaze at the stars, or enjoy your coffee in the cozy indoors.

Popular amenities for Mayo Lake holiday rentals