
Guest house holiday rentals in Mission Bay, San Diego
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Top-rated guest house rentals in Mission Bay, San Diego
Guests agree: these guest house rentals are highly rated for location, cleanliness and more.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for guest house rentals in Mission Bay, San Diego
Family-friendly guest house rentals

Adorable San Diego Guesthouse

Poolside Ocean View Studio

San Diego Shangri-La

Spacious, private Mt. Helix country style studio
Charming Seashell Cottage Overlooking Garden

New Guest House - North Park

OB studio, ocean views, hot tub & garage parking!

Law Street Retreat
Guest house rentals with a patio

Adorable cottage in Talmadge

Free Bikes. 5 min walk to Windensea Beach La Jolla

Private 1 BR Paradise retreat

Sunset Cliffs Studio

Charming Casita with City and Bay Views

Cozy, Quiet and Private Backyard Studio Escape

Heart of SD | Zoo Nearby | Private Patio | Central

Loft Cabin-Night Cinema+Hot Soaking Tub+Views!
Guest house rentals with a washing machine and dryer

Casita at the Cliffs

Stunning Guest House 15 min. from Zoo, Downtown

Relaxing Oasis - short walk to shops & recreation

Beautiful Private Villa walk to beach

Carrie’s North Park Casita, in Heart of San Diego

Bay Ho Cottage w/ Ocean & Bay Views and Roof-Deck

Clean Cozy Private Guesthouse - Central San Diego

Beautiful Historic Home and Gardens Near Downtown!
Quick stats about guest house rentals in Mission Bay, San Diego
Total rentals
20 properties
Nightly prices starting at
$153 SGD before taxes and fees
Total number of reviews
2.8K reviews
Rentals with dedicated workspaces
10 properties have a dedicated workspace
Wifi availability
20 properties include access to wifi
Popular amenities
Kitchen, Wifi and Pool
Destinations to explore
- Townhouse rentals Mission Bay
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- Family-friendly rentals Mission Bay
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- Cottage rentals Mission Bay
- Rentals with an EV charger Mission Bay
- Rentals with a firepit Mission Bay
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- Beachfront rentals Mission Bay
- Apartment rentals Mission Bay
- Pet-friendly rentals Mission Bay
- Rentals with pools Mission Bay
- Rentals with a sauna Mission Bay
- Rentals with breakfast Mission Bay
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- Rentals with a washing machine and dryer Mission Bay
- Family-friendly rentals Mission Bay
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- Rosarito Beach
- Oceanside City Beach
- Belmont Park
- Tijuana Beach
- Torrey Pines State Beach
- Pacific Beach
- Coronado Beach
- San Clemente State Beach
- SeaWorld San Diego
- Coronado Shores Beach
- Oceanside Harbor
- San Onofre Beach
- University of California San Diego
- LEGOLAND California
- Black's Beach
- San Diego Zoo Safari Park
- Balboa Park
- Trestles Beach
- Pechanga Resort Casino
- Liberty Station
- Sesame Place San Diego
- Moonlight Beach
- Playas Los Buenos
- USS Midway Museum