Guest house holiday rentals in San Diego

Find and book unique guest house rentals on Airbnb

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Popular amenities for guest house rentals in San Diego

Family-friendly guest house rentals

Top guest favourite
Guest house in Talmadge
4.98 out of 5 average rating, 209 reviews

Lovely Guesthouse in garden setting

RamonaRating, 5 stars7 months ago
We are so grateful to have been able to stay at Gwynn's place, it is so peaceful and lovely. Like a secret garden getaway. We loved all the small touches, and beauty of the space. Gwynn made us feel very welcome and comfortable! The pool is amazing and the outdoor spaces are delightful. Can't wait to stay here again.
Superhost
Guest house in Pacific Beach
4.84 out of 5 average rating, 365 reviews

Pacific Beach Guest House With Garage and A/C

ElinorRating, 5 stars2 weeks ago
This was our second stay at Gina’s. We can get to the beach, a great coffee shop, and brewery with a 5 minute walk. It is a perfect spot for two people. It will always be our go to spot when in San Diego.
Top guest favourite
Guest house in La Mesa
4.99 out of 5 average rating, 279 reviews

Spacious, private Mt. Helix country style studio

RhondaRating, 5 stars1 month ago
Absolutely worth it. Beautiful place. Cozy with gorgeous gardens. Also a nice welcome touch of bowl of fruits, chocolates and plenty to drink. Loved it.
Guest favourite
Guest house in Mission Hills
4.92 out of 5 average rating, 424 reviews

La Casita - Fully Updated Casita in Mission Hills

MollyRating, 5 stars1 week ago
The casita was perfect for one or two guests, intimate space but did the job. It was very clean, in a nice and quiet neighborhood. We took a walk one of the mornings to a nearby coffee shop which was very peaceful and enjoyable. The location is a short drive to downtown and the beach which was very convenient. I would stay here again.
Top guest favourite
Guest house in Greater North Park
4.97 out of 5 average rating, 187 reviews

New Guest House - North Park

SarahRating, 5 stars2 weeks ago
This property was perfect. So beautiful, cozy, clean and well-equipped. It felt private but was a short walk to great restaurants, coffee shops and cute boutiques. We were traveling with an infant and Lynae went above and beyond in providing little extras that helped to make things easy for us. Would gladly stay here again.
Top guest favourite
Guest house in El Cajon
4.98 out of 5 average rating, 223 reviews

Fletcher Hills - modern 1 BR.Easy, no step access.

DesireeRating, 5 stars5 days ago
This air bnb was the best place we could have stayed in San Diego. It had everything we needed and there were so many thoughtful touches. All I wanted was a Southern California beach vacation and Kristen had all of the gear we needed for that. We went to several beaches during our stay and it was about a 30 minute drive to every beach we went after waiting out morning rush hour traffic. Her backyard was my favorite part of our trip as we love watching sunrises and sunsets and it was so peaceful with great views. There is a lot of natural light in the air bnb as I didn’t understand initially there are solar tube lights throughout the unit which I thought were really cool. The air bnb is in a safe and quiet neighborhood and is a convenient location. The bed itself was very comfortable and we enjoyed being able to cook meals with a full kitchen and be able to do laundry. I would definitely will return when back in San Diego.
Guest favourite
Guest house in San Diego
4.93 out of 5 average rating, 195 reviews

Cosy quiet Guesthouse near SDSU

SandyRating, 5 stars1 month ago
Desiree is such a sweet host! My husband, five month old, and I stayed in her Airbnb and we very much enjoyed our time. The place was well kept and clean. She had the guest house stocked with all the essentials which made it so nice and convenient. Anytime we had a question or request, she was quick to respond and resolve. The location is close to many great coffee shops, restaurants, and things to do. Glad we found this place and would definitely book it again in the future!!
Top guest favourite
Guest house in Sherman Heights
4.96 out of 5 average rating, 534 reviews

Romantic Private Garden Studio Near Downtown

DeborahRating, 5 stars1 week ago
Great place! Beautiful garden. The studio is cozy but you’ll have everything you’ll need. Highly recommend.

Guest house rentals with a patio

Top guest favourite
Guest house in Escondido
4.99 out of 5 average rating, 138 reviews

Garden Casita

EbehlinRating, 5 stars2 days ago
We enjoyed our stay at la casita, it was peaceful and felt like home. La casita is stunning and has a beautiful garden. We love la casita and for sure will be back whenever we visit again. Thank you pete for allowing us to stay for the weekend ✨
Top guest favourite
Guest house in La Mesa
4.99 out of 5 average rating, 117 reviews

Private 1 BR Paradise retreat

LyndaRating, 5 stars1 week ago
Comfortable, cozy apartment with everything you could possibly need. Lovely setting that was very quiet. We were in town visiting family and did not have time to enjoy the pool and patio much but really appreciated the amenities. John and Jeanne were the best hosts we have ever had a AirBnB! Thank you both for such a great stay!
Top guest favourite
Guest house in La Mesa
4.97 out of 5 average rating, 205 reviews

Da Hui Hut - La Mesa’s best view and spa

JerryRating, 5 stars2 weeks ago
We've visited San Diego for years and enjoy this area of the city to visit family, get great mid-eastern food and visit Mount Helix. Mr. Helix has spectacular views from the Mexican Border to North County San Diego and this Da Hui Hut gave a front row seat since its located on it! The Hawaiian atmosphere made my wife feel like see was back home in Kona. This place offered exceptional value and we can't wait to visit again.
Top guest favourite
Guest house in Golden Hill
4.98 out of 5 average rating, 164 reviews

Cozy Urban Casita! Near Zoo, Gaslamp and Coronado

MiguelRating, 5 stars5 days ago
Amazing host! The space was very clean and a lot better than it looks in the pictures. I would definitely consider coming to this place again, especially considering the location. Overall excellent experience!
Guest favourite
Guest house in Serra Mesa
4.95 out of 5 average rating, 106 reviews

Cozy, Quiet and Private Backyard Studio Escape

JoeeRating, 5 stars3 weeks ago
I had an absolutely wonderful stay at Stephanie's place! The space was spotless and made me feel right at home. The location was fantastic and the check-in process was incredibly easy. Stephanie was an outstanding host, always quick to respond to any questions. I especially loved the rain shower! I highly recommend this Airbnb to anyone visiting San Diego and would definitely love to stay here again!
Top guest favourite
Guest house in Greater North Park
4.98 out of 5 average rating, 126 reviews

New (2022) North Park Abode w/ Roof Deck

ClairRating, 5 stars3 days ago
Had a gorgeous stay in San Diego! A quiet and gorgeous neighborhood that was close to everything we wanted to do. Everything was within 20 minutes of driving. Lauren and Boomer had easy instructions on how to check in and where to go. They had an even easier check out process, which was amazing. We will definitely stay with them again the next time we visit San Diego!
Superhost
Guest house in City Heights
4.86 out of 5 average rating, 266 reviews

Heart of SD | Zoo Nearby | Private Patio | Central

TatianaRating, 5 stars1 week ago
Was quiet but still close enough to all the activities and restaurants. Perfect for a couples getaway.
Guest favourite
Guest house in San Diego
4.89 out of 5 average rating, 217 reviews

Central studio w/ private outdoor space & parking

AnnaRating, 5 stars3 weeks ago
We stayed here for our Honeymoon Getaway, and I think this was just perfect for it! It had everything we needed as a young couple there to checkout the town. Nice fully stocked little kitchen perfect to prepare a few things in house, or have a refrigerator and microwave to save the leftovers after eating out. They even a few breakfast items and things stowed away in the pantry closet that we found very helpful. Everything was as described, and very comfortable and clean. We would stay again 🥰

Guest house rentals with a washing machine and dryer

Guest favourite
Guest house in La Jolla
4.98 out of 5 average rating, 419 reviews

Beautiful Private Villa walk to beach

CarolRating, 5 stars3 days ago
Kim is a cheerful, responsive, and helpful host, while being very respectful of our privacy and letting us be. She is a Perfect Airbnb host. Truly. She is very kind and knows the area, has a great presence and her place... just beautiful. Very comfortable. Immaculate. Has a full kitchen in an efficiency style with Sub-Zero fridge and gas range. I stayed with my newly pregnant daughter and took the sofa-bed so she could have the queen bedroom, and I must say, the sofa-bed is the most comfortable bed in the world. Very nice. High end. Her Villa is decorated in the most beautiful way and her gardens are like Eden itself. We can't wait to stay again and hope to see Kim again too. It was that good. Thank you so very much, Kim! You are the best!
Top guest favourite
Guest house in La Mesa
4.99 out of 5 average rating, 189 reviews

Stunning Guest House 15 min. from Zoo, Downtown

HjRating, 5 stars1 week ago
Amazing cottage with a full kitchen and bathroom as well as a living room, decorated with exceptional sense of aesthetics. Its double doors opens to a great porch where you can enjoy wine and cheese at California evening, but you can also enjoy the clear sky during the day through the screen doors. It is so close to the downtown La Mesa with many great restaurants. Lynn was a great host and her freshly baked bread was so tasty as well. One of the best AirBNB I have experienced; highly recommended.
Guest favourite
Guest house in Golden Hill
4.87 out of 5 average rating, 492 reviews

The Golden Hill mosaic "casita"

KevinRating, 5 stars1 week ago
Very nice place, safe neighborhood, walkable to some stuff. Would repeat.
Top guest favourite
Guest house in Oceanside
5 out of 5 average rating, 188 reviews

Guesthouse - prime location next to BEACH!

MichelleRating, 5 stars2 weeks ago
If you're looking for peace, relaxation and an escape from the stress of reality, this is the place. Peaceful, tranquil and serene. Walking distance to bike rentals, various coffee shops and restaurants. A staircase leading to the beach pretty much right outside your door and might I add glorious sunsets in the distance. I'd return!
Top guest favourite
Guest house in Rancho Santa Fe
4.99 out of 5 average rating, 167 reviews

Rancho Relaxo / Spacious Detached Guest House

ChenetteRating, 5 stars1 week ago
Had the most relaxing solo vacay at Britt and Susie’s pool house. The house was exactly as described. I felt safe and comfortable. I was greeted by Britt when I arrived and he explained how to use all the house amenities. I enjoyed the pool and hot tub each day, which were very clean and well-landscaped. This place is a dream for a couple or solo traveler like me!
Top guest favourite
Guest house in Carlsbad
5 out of 5 average rating, 221 reviews

Ocean/Lagoon View/New Luxury Casita /Walk To Beach

AlexaRating, 5 stars2 days ago
This was the most perfect stay for my wedding weekend, the view is amazing and the private patio was so peaceful. I was able to get ready there the day of and feel so relaxed. They also accommodated our little bulldog which was so important and kindly gifted us with champagne. I would recommended this stay to everyone!
Top guest favourite
Guest house in Greater North Park
4.95 out of 5 average rating, 610 reviews

Early 1900's Carriage House w/Views

MarcelRating, 5 stars4 days ago
Nice, quiet and save neighborhood. Extremely nice and helpful hosts. Would definitely come again and highly recommend
Guest favourite
Guest house in City Heights
4.95 out of 5 average rating, 151 reviews

Cozy Cottage 1/2 mile to North Park close to dtwn

JasonRating, 5 stars3 weeks ago
Excellent place. We loved the location relative to the sites we wanted to see. Free parking, laundry, very well stocked kitchen, comfortable bed. We were very comfortable and happy here. And as a host Wendy was phenomenal. One of the most responsive hosts I’ve had the pleasure of connecting with on Airbnb. Thank you Wendy!!!

Quick stats about guest house rentals in San Diego

  • Total rentals

    1K properties

  • Total number of reviews

    101K reviews

  • Family-friendly rentals

    140 properties are a good fit for families

  • Pet-friendly rentals

    240 properties allow pets

  • Rentals with a pool

    90 properties have a pool

  • Rentals with dedicated workspaces

    540 properties have a dedicated workspace

Destinations to explore