
House holiday rentals in Pickens County
Find and book unique houses on Airbnb
Top-rated house rentals in Pickens County
Guests agree: these houses are highly rated for location, cleanliness and more.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for house rentals in Pickens County
House rentals with a pool

Keowee Key Luxury Condo - Stunning Views!

Lake Keowee Access-Dock-Pool-Grill-Clemson 17 Min

Clemson football 15 minutes away. 2 night minimum.

Historic Pendleton SC

Golf view, lake access, 3 pools!

Cottage close to Clemson

Tiger’s Lair

The Willows
Weekly house rentals

Easley Cottage: near Clemson & Greenville & Lakes

Robin’s Nest- Cottage in the Woods

Jess & Bailey's Easley Escape

Vaulted Ceilings & Accent Windows--1 mile from CU

King Bed Quiet Modern Farmhouse w/ HUGE yard

Cozy Brick House

Respite House

Sunset Cottage -Waterfront with Kayaks
Private house rentals

Elegant 3BR Near Wed Venu | Grill+ Golf Next Door

Singing Pines Cottage

Raven's Ridge

Lakefront Mid-Century Dream Home / 3 mi to Clemson

Taking it Easley/FirePit/Near Dwn GVL/HtTub/Silos

New! Charming 4/2.5 Modern Home in Clemson, SC

Lake Keowee SC Lakehouse Escape

Forest Getaway 5 mins to Clemson- Private Entrance
Destinations to explore
- Rentals with a washing machine and dryer Pickens County
- Cabin rentals Pickens County
- Rentals with lake access Pickens County
- Flat rentals Pickens County
- Waterfront rentals Pickens County
- Rentals with a fireplace Pickens County
- Fitness-friendly rentals Pickens County
- Rentals with breakfast Pickens County
- Rentals with outdoor seating Pickens County
- Rentals with a kayak Pickens County
- Rentals with a firepit Pickens County
- Rentals with pools Pickens County
- Rentals with a patio Pickens County
- Motorhome rentals Pickens County
- Rentals with a hot tub Pickens County
- Pet-friendly rentals Pickens County
- Apartment rentals Pickens County
- House rentals South Carolina
- House rentals United States
- Blue Ridge Parkway
- River Arts District
- Black Rock Mountain State Park
- Gorges State Park
- Tugaloo State Park
- Chimney Rock State Park
- Mountaintop Golf & Lake Club
- Table Rock State Park
- The North Carolina Arboretum
- Tallulah Gorge State Park
- Tryon International Equestrian Center
- Lake Lure Beach and Water Park
- Ski Sapphire Valley
- Wade Hampton Golf Club
- Jump Off Rock
- Maggie Valley Club
- Biltmore Forest County Club
- Old Edwards Club
- Vineyards for Biltmore Winery
- Victoria Valley Vineyards
- French Broad River Park
- Woolworth Walk
- Thomas Wolfe Memorial
- Discovery Island