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Holiday rentals with lake access in Pickens County

Find and book unique lake access rentals on Airbnb

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Popular amenities for lake access rentals in Pickens County

Lake access house rentals

Guest favourite
Home in Seneca
4.95 out of 5 average rating, 73 reviews

Good Times @ Clemson / Lake Hartwell

DanRating, 5 stars1 month ago
Mike’s place was perfect for our group. Clean, comfortable and only 15 minutes to Clemson.
Top guest favourite
Home in Pickens
5 out of 5 average rating, 52 reviews

Tekoa at Table Rock

MiaRating, 5 stars5 days ago
We loved staying at Tekoa. The views were incredible and the home was well appointed. Layne had so many great extras - skewers for the fire pit, walking sticks, a park pass for easy access to Table Rock. It was clean and comfy, too. Plenty of space - you’ll love it there!
Guest favourite
Home in Seneca
4.92 out of 5 average rating, 37 reviews

Lakefront Mid-Century Dream Home / 3 mi to Clemson

SusanRating, 5 stars1 month ago
We had a lovely stay in Lauren's home. You feel like you're living in the Brady Bunch house! Classic 1960s everything. The beds and seating were all very comfortable, and we enjoyed the abundant decks, the hammock, the kayak, the TV... the kitchen had everything you could want, and we appreciated the extra bag of ice and cans of sparkling water they left for us. We highly recommend it. If you're more noise-sensitive, we recommend the downstairs bedroom, which is insulated from the noisier/brighter open layout of the upstairs.
Top guest favourite
Home in Six Mile
5 out of 5 average rating, 29 reviews

Lakefront luxury home w/panoramic view & Boat Slip

KelleyRating, 5 stars5 months ago
What an amazing stay! The lake house is so unique, and there is so much to do without even having to leave. It has three separate levels with a room and bathroom on each. The upstairs has a jacuzzi tub overlooking the beautiful lake. The morning fog on the lake from the third floor is magical. The bottom floor is the perfect place to hang out with your entire family, as there is ping-pong, darts, pool, and board games. We had an absolute blast and would book again. I can't imagine how much fun it would be in the summer with warmer weather and the lake. Everything was spotless and immaculate, and the location was extremely safe and close to everything you needed. Host was excellent. Highly recommend!
Top guest favourite
Home in Seneca
4.99 out of 5 average rating, 193 reviews

Lakeside @ Lake Hartwell in Clemson, SC 🐟🌅🚤

MickeyRating, 5 stars1 month ago
Can’t say enough great things about the location and the host. Property exceeded all our expectations for a great Easter weekend with our family. Highly recommend to anyone looking for a lake get away close to Clemson and Seneca
Superhost
Home in Six Mile
4.87 out of 5 average rating, 38 reviews

Lake Keowee Access-Dock-Pool-Grill-Clemson 17 Min

EliRating, 5 stars1 week ago
We were there for a work trip and it was a very comfortable place to stay. Clean, quiet and relaxing. Will definitely stay again!
Guest favourite
Home in Easley
4.92 out of 5 average rating, 25 reviews

Emerald Shore

BrysonRating, 5 stars4 days ago
This was a beautiful home with everything you need! Pretty pond in the back. There were two ducks and they were so cute to watch. Was a comfortable spacious house and lovely place to stay, would recommend!!
Top guest favourite
Home in Salem
5 out of 5 average rating, 28 reviews

Golf view, lake access, 3 pools!

StephanieRating, 5 stars3 weeks ago
We had a wonderful stay at the Sail Loft over Memorial Day weekend! From the moment we arrived, we felt right at home. The space is so cozy, beautifully decorated, and full of thoughtful touches—it’s clear that every detail has been carefully considered. It’s just like the photos, only better in person! Nichole was the perfect host—kind, responsive, and welcoming. She guided us throughout our stay, making sure everything went smoothly and that we felt comfortable and cared for. We loved enjoying the Keowee Key amenities, especially the pool and dining at the club’s restaurants. It truly felt like a hidden gem! We’re already looking forward to coming back soon. Highly recommended for anyone looking for a peaceful retreat with all the comforts of home!

Apartment rentals with lake access

Flat in Seneca
4.8 out of 5 average rating, 5 reviews

Lakeside Clemson apartment

CeilRating, 5 stars2 months ago
Wonderful stay. It was very quiet. The location was perfect. Condo was clean and comfortable. I asked for a last minute change and Dorian was very gracious with accommodating me. I will stay there again!
Superhost
Flat in Sunset
4.74 out of 5 average rating, 19 reviews

"Greenbrier" Home in the Joccassee Wilderness

AprilRating, 5 stars2 months ago
My family and I absolutely enjoyed our little getaway here. The first night we woke up to it being over 85 degrees in the home but Tami was quick to respond and immediately had two window A/C units placed in the home to keep it cool. We are already talking about our next adventure and staying at this location again! Thank you Tami for allowing my family to celebrate the Easter holiday here!
Top guest favourite
Flat in Six Mile
5 out of 5 average rating, 23 reviews

Condo and Lake Keowee

SuzanneRating, 5 stars1 day ago
It was a very cute quiet place, well stocked just in case you happened to forget something. The pool was just down the hill. It was a short drive to Clemson and other small towns. The lake was right across the road. And you could see the mountains from a distance. The host was very friendly and responsive too! We just loved our stay.
Flat in Salem

Beautiful Lake Keowee Condo

BethRating, 5 stars13 months ago
Will stay again soon.
Flat in Seneca
4.67 out of 5 average rating, 3 reviews

Apartment in Seneca

TommyRating, 5 stars7 months ago
Great location. The place is really decorated well, and Stuart made the stay seem personal, not like a hotel experience.
Flat in Clemson
4.68 out of 5 average rating, 25 reviews

Scenic Retreat 5 Min to CU + Pool

JustinRating, 5 stars2 months ago
Really nice place right on the water. Host was helpful and responded quickly.
Flat in Seneca

Gameday Getaway on Lake Hartwell - close to campus

JillRating, 5 stars9 months ago
Amelia is a super host! She was always responsive, before and during our stay with clear communication about everything. She provided flexibility on check-in and check-out. The condo is about a 5 minute drive to Clemson's campus, which made it the perfect location for us to visit our son there and attend a football game. It was exactly as described/ pictured, squeaky clean, nicely updated, and quiet (on the 3rd floor). It is located in an older complex, but inside the condo has been completely updated with brand new flooring, bathrooms, countertops, appliances, etc. TVs are in every room, but you will probably not want to stay inside much....it's on the lake! We didn't get down to the lake, but we could see the lake from the balcony of the condo. Parking was always available all weekend, directly in front. Everything we could have possibly needed was there, and it was in places we would expect to find it! We are already picking dates to go back to this AirBNB! Thank you, Amelia!
Top guest favourite
Flat in Seneca
5 out of 5 average rating, 25 reviews

3BR Ground floor condo - 2.4 Miles to Death Valley

SueRating, 5 stars1 month ago
We were extremely pleased the moment we walked into the unit. Beautiful inside, room for everyone, kitchen had everything we needed to cook, super quiet and peaceful. The coffee bar and water fridge was stocked, assorted munchie basket and the quality bathroom towels were the added touches that a lot of previous Airbnbs have missed. The hosts were kind and proactive and we did not need one thing. My adult kids sat down for chess and that was the bonding time we’ve been wanting to have. The patio/balcony provided the best coffee and cocktail time. My favorite place 💜🧡 GO TIGERS

Lake access cottage rentals

Cottage in Salem
4.75 out of 5 average rating, 32 reviews

Lake Front Cottage/Floating Dock

MadisonRating, 5 stars1 month ago
Lara's place was the perfect get away for the weekend. The location on the lake is perfect right by a boat ramp and a close boat ride to the waterfall on Keowee. The house was so cozy and comfortable and I loved the privacy. I will absolutely be sharing this spot and book again soon!
Guest favourite
Cottage in Sunset
4.95 out of 5 average rating, 114 reviews

River Cottage Nature Privacy

BrandiRating, 5 stars1 month ago
I stayed here a week for work. It was the perfect place to come home to every night. I did get to visit Lake Jocassee and Twin Falls on my last day--highly recommend! Matt was great, and the charming little cabin was a peaceful retreat in a gorgeous location! It had everything I needed--even things I didn't know I would need (like poison ivy soap to use as a precaution after I'd been romping around in the wilderness for work)! I'd definitely come back here, whether I'm in the area for work or play.
Guest favourite
Cottage in Easley
4.93 out of 5 average rating, 68 reviews

Cozy Cottage on the lake

DonnaRating, 5 stars11 months ago
We had a wonderful stay at the cottage. We loved the pool and the grankids loved it too. The cottage was clean , comfy, and cozy. The cottage was very peaceful and private, located on a dead end road. We highly recommend a stay . Will book again.
Cottage in Salem
4.82 out of 5 average rating, 62 reviews

Jocassee Landing Lake Cottage - 1 mi to Boat Ramp!

BrooklynRating, 5 stars1 month ago
It’s was a beautiful place, very clean and close to the lake. Over all it was a great get away, very little traffic and so quiet. We had a great time would definitely stay again!!
Top guest favourite
Cottage in Six Mile
4.99 out of 5 average rating, 197 reviews

Lake Keowee Waterfront Cottage - Private Retreat

ChrisRating, 5 stars2 days ago
What can I say about this beautiful property that hasn't been said already...? WOWWW is good for starters. Like heaven on earth. I hope too many people dont find out about this amazing property because we want to come back LOL. Even nicer than the pictures! And Kurt is a GREAT Host ! We will be back thank you Kurt !!!
Top guest favourite
Cottage in Pickens
4.98 out of 5 average rating, 62 reviews

At Table Rock+ Private Trail+Fire Pit+King Bed+BBQ

JonRating, 5 stars4 days ago
Great spot for a family getaway! The home is perfectly located for enjoying the nearby state park and exploring the surrounding area. There's plenty of space both indoors and out to relax, with two large and very comfortable rooms-each with its own bathroom-which made things super convenient. The basement has been nicely updated and includes two single beds, though with narrow stairs and low lighting, It's probably better suited for kids or teens rather than adults. While the keyless entry didn't work as expected, the host had a solid backup plan in place, and everything else ran smoothly. The house was clean and well-kept, though we did notice a strong smell of garbage when we first arrived and ended up grabbing some air fresheners. Overall, a great experience in a beautiful location-would definitely come back!

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