
Townhome holiday rentals in Pickens County
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Top-rated townhouse rentals in Pickens County
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Amenity Rich Keowee Resort - 25 min to Clemson
Enjoy the Best of Both Worlds in our spacious 4-bedroom, 3-bath townhome in the gated Keowee Key Resort. Where lake life, mountain views, and resort amenities come together for the perfect getaway. Spread over three levels with two living rooms and two sunrooms, the home offers plenty of space for families, couples, or friends traveling together. When you're visiting Lake Keowee, Clemson University, or the Blue Ridge Mountains, this home is a comfortable base for both adventure and relaxation.

2BR 2.5 Downtown Oasis Full Kitchen | Pet Friendly
Welcome to The Thistle - Easley Base Camp for Greenville Adventures & Game Day Escapes Planning Clemson game weekend, Greenville getaway, or a cozy escape w/ family? The Thistle puts you just 18 minutes from Clemson 13 minutes from downtown Greenville's vibrant dining/ nightlife, yet nestled in charming Easley w/ tree-lined streets and a genuine sense of community. This isn't just a rental—it's your private townhome designed for guests who want modern comfort without sacrificing local charm.

Resort Pool & Spa 3BR 3BTH w Loft, Family Gameroom
Escape to this spacious three-story, family-friendly home w bedrooms, baths, and decks on each level—perfect for large families (sleeps 9). Pack ’n Play available, easy front-door parking, & access to resort pools, spa, and sauna included. It's a professionally cleaned, dog-friendly 3BR, 3BA townhome w loft/3 living spaces. Enjoy wooded rolling hills w wildlife, resort amenities (some activities like golf or boat rentals have fees), ping-pong, board games, and a deck fireplace under the stars.

Rosehill Villa at Clemson Botanical Gardens
Newly renovated 4 bedroom 3.5 bathroom townhouse. Open concept kitchen, living room and dining room. Small deck located off the kitchen and dining room to relax with coffee. Bring the whole family to this great place with lots of room for fun. Clemson Botanical gardens are a 10 minute walk down a foot path and continue on for another 25 minutes to reach Memorial Stadium (football), Littlejohn Coliseum (basketball), Doug Kingsmore Stadium (baseball), and Brooks Theater where the Tigers play.

Seneca Escape w/ Screened Patio: Near Lakes!
Spacious Backyard | 3 Mi to Memorial Stadium | Located in the Millbrook Community Whether you're drawn to boating adventures on Lake Keowee, family fun at the Oasis Ranch Mini-Golf, or game days at Clemson University, this 3-bed, 2-bath vacation rental townhome offers the perfect base for your Seneca and Clemson escapades! Take a break from your excursions by relaxing in an Adirondack chair or playing cornhole in the yard. As evening falls, settle in for a movie night beside the Smart TV.

The Deck House at Keowee Key Lake
Welcome to The Deck House. A 10 min. walk to Lake Keowee, a beautiful clear water lake with summer water temps in the upper 80s. Rent a boat, fish, or enjoy a sand beach for a swim. A short 10 min. drive for free access to Tennis, Pickleball, full fitness center, exercise classes and indoor and outdoor pools. Golf, boat rentals are also available for additional fees. Clemson fan? 20 mins to the football stadium. Is there more? Yes! See pictures to confirm you made the right choice!

Walk to Lake Keowee: Salem Townhome w/ Deck
Walk to Private Beach | Fireplace | Newly Renovated | 10 Mi to Clemson Escape to this 4-bedroom, 3-bath vacation rental in Salem! Perfect for families, this townhome offers ample space to unwind after exploring Lake Keowee or Table Rock State Park. With a full kitchen and access to community amenities, this townhome has everything you need for a memorable retreat! Be sure to relax by the community pool or play a round of golf before cozying up by the fireplace!

Exclusive Luxury Escape
Welcome to this cozy place in Easley, SC—perfectly located between Clemson and Greenville! Just 20 minutes from Clemson University and downtown Greenville, this space is ideal for college visits, game days, or exploring the Upstate. Enjoy a quiet, comfortable stay with modern amenities and easy access to local dining, shopping, and outdoor activities. Whether you're here for a Tigers game or a weekend getaway, our home offers the perfect base for your adventure.

Boat Dock: Lake-View Retreat 5 Mi to Dtwn Clemson
Whether you're here for a relaxing lakefront getaway or to cheer on the Tigers, this impressive Seneca house is the perfect choice for you! Ideally situated on a private lot of nearly one acre on picturesque Lake Hartwell, this vacation rental boasts ample deck space, three screened porches, and a media room perfect for watching the big game. You'll love being within four miles of Clemson University, museums, parks, shops, restaurants, and more!

Modern and Spacious Townhome 10mins to DT
This expansive 4BR/4.5BA townhome offers the perfect mix of privacy and space. Each bedroom includes its own ensuite bathroom, queen-size bed, and walk-in closet. The open-concept living area flows into a modern kitchen with stainless-steel appliances, granite countertops, and a full-size washer and dryer. Perfect for group stays, work trips, or families looking for simple comforts and convenience.

Royal Tiger - Walk to Death Valley!
Charming & Updated Townhouse - Walk to Clemson's Death Valley! Immerse yourself in the vibrant spirit of Clemson from this beautifully updated townhouse, ideally situated within walking distance to the legendary Death Valley Stadium, home of the Clemson Tigers. Perfectly designed for game day excitement and cozy evenings, this home offers the perfect blend of comfort, convenience, and style.

TigerTown HideAway
Perfect spot for your visit to Clemson. 4 bedroom/4.5 bathroom close to everything. Property backs up to Clemson’s Botanical Gardens. Beautiful Lake Keowee and Hartwell is a short drive away. Lake Jocasse is about an hours drive. 2 minute drive to downtown. Near restaurants and grocery stores. This townhome can sleep 10+ Anderson - 15 min Greenville -45 min
Popular amenities for townhouse rentals in Pickens County
Townhouse accommodation with a washing machine and dryer

Tall Ship 331 Waterfront 2BR Condo in Salem, SC

Keowee Key Townhome with Amenities - Pet Friendly

Tiger Nest in Clemson, SC!

Hike & Fish: Lake Keowee Retreat w/ Shared Dock!

Salem Vacation Rental w/ Lake Keowee Access!

Tiger Town Getaway: 2 Mi to Downtown & Campus!

Charming Seneca Home - 3 Mi to Memorial Stadium!

Slice of Heaven at the Clemson Dike
Townhouse rentals with a patio

Fun Lake Keowee TownHse Golf Tennis Picklball Pool

Walk to Silos | 2BR 2.5BA Townhome + Chef Kitchen

Rosehill Villa two at Clemson Botanical Gardens

Modern 2BR 2.5 Bath Loft Near Clemson & Greenville

Gorgeous Clemson | Greenville Retreat 2BR 2.5 Bath
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- Clemson University
- Blue Ridge Parkway
- Tryon International Equestrian Center
- Biltmore House
- The North Carolina Arboretum
- Black Rock Mountain State Park
- River Arts District
- Chimney Rock State Park
- Table Rock State Park
- Gorges State Park
- Tallulah Gorge State Park
- Devils Fork State Park
- Lake Lure Beach and Water Park
- Harrah's Cherokee Center - Asheville
- DuPont State Forest
- Bon Secours Wellness Arena
- Ski Sapphire Valley
- Fred W Symmes Chapel
- Chattooga Belle Farm
- Woolworth Walk
- Jump Off Rock
- French Broad River Park
- Saint Paul Mountain Vineyards
- Looking Glass Falls









