
Guest house holiday rentals in Santa Cruz
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Top-rated guest house rentals in Santa Cruz
Guests agree: these guest house rentals are highly rated for location, cleanliness and more.

La Casita, Finca La Vispera
La Casita, is a perfect place to spend a couple of days with your partner, it is located inside Finca "La Vispera", we have a Parque Nativo, Café Jardín, Herbolario, great view. You’ll love my place because of the location, the people, the neighborhood, the outdoors space, and the ambiance. My place is good for couples, solo adventurers, families (with kids), big groups, and furry friends (pets). You also will enjoy our vegetable Garden. You can collect the vegetables and enjoy a great meal.
LocationHospitalityCleanliness

Cozy family home in Santa Cruz de la Sierra
Family house of 320 square meters, on the second floor, with all the household goods and linen, wonderful views from its 30-meter terrace. Ideal for families who want to have a quiet stay of any duration in the City of Santa Cruz de la Sierra. Very well connected with several bus lines that lead to the entire city and surroundings and very close to the Cotoca Sanctuary. Nearby you will find all kinds of services, breakfasts, meals, markets, shops, etc.
LocationFamilyKitchen

Quinta El Retorno: comfortable house with 2 bedrooms.
Welcome to Quinta El Retorno, a space surrounded by nature that offers peace and relaxation. The house has two separate bedrooms, each with a private bathroom, a shower with hot water, air conditioning, and a built-in closet. It can accommodate up to 5 guests, making it ideal for families, couples, or small groups. In addition, it offers covered parking for two vehicles, Wi-Fi, and a large outdoor gallery for enjoying the outdoors.

Spacious house with a patio and parking
Guest house, with large patio and grill (churrasquera), in a very quiet area. Air conditioning in all rooms, water heater (hot water), Wi-Fi, spacious living room. Suite with private bathroom. Shared bathroom, sofa bed and large sofa on the ground floor. (Up to 4 people can sleep comfortably) Address: km 8, Barrio 14 de Agosto, Calle 3 Between double track la guardia and radial 17 and a half

Casiopea Eco-Friendly Room
Relax and enjoy a moment with nature, 10 minutes from the municipality of La Guardia and 3 minutes from the tranca al Torno entering through Cañada Seca. Room with air conditioning, 2 1/2 seater bed with option to add 1 or 2 extra mattresses; Grill, electricity, water, wifi, ample space for hiking trails. Fruit trees, easy access with nearby shops to provide food. Owners live on site.
ValueLocationAccuracy

Room in the center, two minutes from everything!
Experience staying in the heart of Santa Cruz, just 3 blocks from the main square. Our bright and cozy room awaits you in a safe and lively area: museums, cafes, bars, shops and historical corners are within walking distance. Ideal for those seeking comfort, style, and an unbeatable location. With WiFi, details designed for your rest and attention that will make you feel at home.
LocationValueComfort

Complete centric apartment with garden and pool
Complete centric apartment with an enormous garden and pool. Private apartment with fully staffed kitchen, private bathroom and a bedroom with a queensized bed. You'll also have access to the big garden and the pool to relax and refresh yourself. By choosing our accommodation, you’re also supporting Ñañope, a local NGO dedicated to empowering household workers in Santa Cruz.
Hospitality

Window to Amboro Park
Enjoy a partial view of the Amboro mountains, with birdsong in the morning and the sounds of the small forest at night. Sometimes nocturnal monkeys or early-rising agoutis may appear. Though only 4 blocks from the main square, the place is quiet, away from traffic noise. With advance confirmation, tours to the north side of Amboro National Park can be arranged.
LocationValueCheck-in

Private Apartment In Downtown
Welcome to our cozy guest house in one of the most beautiful and safe areas of the center! Just 6 blocks from Plaza 24 de Septiembre, our historic neighborhood offers you a unique experience.
ValueLocationNearby

Centric, accesible, comfy private room w/bathroom
Peaceful private room with a private bathroom in the heart of Samaipata, 50m from the market, 2 blocks to town plaza. Clean, cozy, simple. Basic amenities, NO Kitchen...
LocationValueCheck-in

Holistic Portal House # 1
Enjoy this mystical space of tranquility and harmony where your nights will be restored and revitalized with the energy of the Holistic Portal

Separate room with private bathroom
Relax in this independent accommodation where tranquility is breathed.
Hospitality
Popular amenities for guest house rentals in Santa Cruz
Family-friendly guest house rentals

Posada El Peregrino 7
LocationNearbyBack garden

Colina Verde, Yellow Room
LocationComfortHospitality

Guesthouse
Hospitality

Comfortable apartment in an urban area
LocationValueIndoor spaces

Double or Full Room in Downtown
LocationHospitalityCleanliness

Nature Retreat at Quinta Consciencia
ValueLocationView

Just like home

NEST 2: Centric comfy private room w/bathroom
Guest house rentals with a patio

4 people accommodation+breakfast
Family

Studio #01

Lupita Guesthouse

Exclusive double room in the mountains.

Apartment-style room

Mirador del Cielo - Boutique Apart Hotel 2

1 person accommodation + breakfast

Exclusive Triple Room in the Mountains
Other guest house holiday rentals

Centric and Cozy Studio

Apartment inside a house

Just like home

department to share TamisaIII

Colina Verde, Durazno Room
ValueFamilyBathroom

Apartment in an urban area
ValueLocationLong stay

Relaxing and Executive Apartment in an urban area.
ValueLocationBeach

2 people accommodation + breakfast
LocationIndoor spacesCleanliness
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