
Guest house holiday rentals in Santa Cruz
Find and book unique guest house rentals on Airbnb
Top-rated guest house rentals in Santa Cruz
Guests agree: these guest house rentals are highly rated for location, cleanliness and more.

La Casita, Finca La Vispera
La Casita, is a perfect place to spend a couple of days with your partner, it is located inside Finca "La Vispera", we have a Parque Nativo, Café Jardín, Herbolario, great view. You’ll love my place because of the location, the people, the neighborhood, the outdoors space, and the ambiance. My place is good for couples, solo adventurers, families (with kids), big groups, and furry friends (pets). You also will enjoy our vegetable Garden. You can collect the vegetables and enjoy a great meal.

Horizontal duplex in backyard of house with pool
Enjoy a horizontal duplex (complete) in the backyard of my house. With its own entrance to the duplex, it shares an entrance to the property. Located in a safe and quiet area easily accessible, close to shops, markets, supermarkets, pharmacy, public transportation (blocks from the main avenues), by car 10 min. from the center, 5 min. from the Fexpo, 30 to 40 min. from the airport, 1 block walk from the society of engineers SIB, clinic Montalvo and Urbari.

Cozy family home in Santa Cruz de la Sierra
Family house of 320 square meters, on the second floor, with all the kitchenware and linen, wonderful views from its 30 meters of terrace. Ideal for families who want to have a quiet stay of any duration in the City of Santa Cruz de la Sierra. Very well connected with several bus lines that take you throughout the city and surroundings and very close to the Santuario de Cotoca. Nearby it has all kinds of services, breakfasts, meals, markets, shops, etc.

Spacious house with a patio and parking
Casa de huéspedes, con patio amplio y parrilla (churrasquera), en una zona muy tranquila. Aire acondicionado en todos los ambientes, termotanque (agua caliente), Wi-Fi, amplia sala de estar. Suite con baño privado. Baño común, sofá-cama y sofa amplio en planta baja. (Pueden dormir cómodamente hasta 4 personas) Dirección: km 8, Barrio 14 de Agosto, Calle 3 Entre doble vía la guardia y radial 17 y medio

Room in the center, two minutes from everything!
Experience staying in the heart of Santa Cruz, just 3 blocks from the main square. Our bright and cozy room awaits you in a safe and lively area: museums, cafes, bars, shops and historical spots are just a few steps away. Ideal for those looking for comfort, style and an unbeatable location. With WiFi, details designed for your rest and attention that will make you feel at home.

Complete centric apartment with garden and pool
Complete centric apartment with an enormous garden and pool. Private apartment with fully staffed kitchen, private bathroom and a bedroom with a queensized bed. You'll also have access to the big garden and the pool to relax and refresh yourself. By choosing our accommodation, you’re also supporting Ñañope, a local NGO dedicated to empowering household workers in Santa Cruz.

Casiopea Eco-Friendly Room
Relax and enjoy a moment with nature, 10 minutes from the municipality of the guard and 3 minutes from the lock to the lathe entering by dry canyon. Air-conditioned room, 2 1/2 beds with option to add 1 or 2 extra mattresses; Grill, light, water, wifi, ample space for hiking on trails. Fruit trees, easy access with shops nearby for groceries. Owners live in the place.

Lodge surrounded by nature in the city
We renewed our lodge for more comfort for our guests: Imagine a little house surrounded by trees and plants, easy to go and not far away from city center. We´re living on half a hectar and your new place for working o relaxing is inside this paradise. You´re completely independent from us, with all you need for taking a rest or work, including the swimming pool.

Window to Amboro Park
Enjoy a partial view of the Amboro mountains, with birdsong in the morning and the sounds of the small forest at night. Sometimes nocturnal monkeys or early-rising agoutis may appear. Though only 4 blocks from the main square, the place is quiet, away from traffic noise. With advance confirmation, tours to the north side of Amboro National Park can be arranged.

Double or Full Room in Downtown
New and elegant building located just 2 blocks from the main square, surrounded by shopping malls, restaurants, cafes, jewelry, perfumerias, perfumerias, it is located a couple of blocks from the house of culture, the cathedral, museums, 1 block, banks, 7 street market and various shops and locals.

Private Apartment In Downtown
Welcome to our cozy guest house in one of the most beautiful and safe areas of the center! Just 6 blocks from Plaza 24 de Septiembre, our historic neighborhood offers you a unique experience.

Casa Portal Holístico # 1
Disfruta de este espacio místico de tranquilidad y armonía dónde tus noches serán restauradas y revitalizantes con la energía del Portal Holístico
Popular amenities for guest house rentals in Santa Cruz
Family-friendly guest house rentals

Casa Portal Holístico # 1

Spacious house with a patio and parking

Complete centric apartment with garden and pool

Separate room with private bathroom

Horizontal duplex in backyard of house with pool

Window to Amboro Park

Cozy family home in Santa Cruz de la Sierra

COTTAGE SURROUNDED BY NATURE
Guest house rentals with a patio

Lupita Guesthouse

room#7 with private bathroom.

El Peregrino Inn 2

Mirador del Cielo - Boutique Apart Hotel 2

Posada El Peregrino 3

Apartment-style room

Habitación#6 con baño privado

family home to share
Other guest house holiday rentals

Casa Portal Holístico # 1

Spacious house with a patio and parking

Complete centric apartment with garden and pool

Separate room with private bathroom

Horizontal duplex in backyard of house with pool

Window to Amboro Park

Cozy family home in Santa Cruz de la Sierra

COTTAGE SURROUNDED BY NATURE
Destinations to explore
- Holiday home rentals Santa Cruz
- House rentals Santa Cruz
- Cabin rentals Santa Cruz
- Townhouse rentals Santa Cruz
- Family-friendly rentals Santa Cruz
- Rentals with outdoor seating Santa Cruz
- Rentals with a washing machine and dryer Santa Cruz
- Rentals with a patio Santa Cruz
- Rentals with breakfast Santa Cruz
- Rentals with beach access Santa Cruz
- Smoking-friendly rentals Santa Cruz
- Cottage rentals Santa Cruz
- Rentals with a firepit Santa Cruz
- Hotel rentals Santa Cruz
- Rentals with pools Santa Cruz
- Rentals with an EV charger Santa Cruz
- Boutique hotel rentals Santa Cruz
- Rentals with a hot tub Santa Cruz
- Pet-friendly rentals Santa Cruz
- Rentals with lake access Santa Cruz
- Fitness-friendly rentals Santa Cruz
- Private suite rentals Santa Cruz
- Loft rentals Santa Cruz
- Rentals with a sauna Santa Cruz
- Apartment rentals Santa Cruz
- Beachfront rentals Santa Cruz
- Flat rentals Santa Cruz
- Rentals with a fireplace Santa Cruz
- Serviced apartment rentals Santa Cruz
- Rentals with a cinema Santa Cruz
- Guest house rentals Bolivia