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Holiday rentals in Santa Cruz

Find and book unique accommodation on Airbnb

Top-rated holiday rentals in Santa Cruz

Guests agree: these stays are highly rated for location, cleanliness and more.

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Superhost
Flat in Nueva Gorgona
5 out of 5 average rating, 3 reviews

Sky-High: Ocean & Mountain Views

Escape to this bright, modern 1 bdrm, one-bath condo on the 19th floor of Royal Palm, a sought-after beachfront project. Enjoy panoramic ocean and mountain views. Open-concept dining and living area, ideal for both dining and working. The space is fully equipped, light-filled, and thoughtfully designed for relaxation. Step onto the private balcony and savor the tropical breeze or unwind by the building's pools. Perfect for beach lovers seeking a high-floor retreat with all the comforts of home.

Top guest favourite
A serene outdoor space features a large saltwater pool surrounded by multiple lounge chairs and red umbrellas. Lush greenery is visible in the background, providing a tropical setting under a bright blue sky. A hand holds a beverage in the foreground, adding depth to the scene.
Home in Costa Esmeralda
4.98 out of 5 average rating, 202 reviews

Beach House-Amazing Pool & Jacuzzi - Pet Friendly

Majestic Sands! Come relax with the whole family at this piece of paradise.located in a private beach community in Costa Esmeralda, San Carlos. Few minutes from the Pan-American highway and a few minutes from other local beaches such as Gorgona, and Coronado. It is a 5-minute walk to our beach, or if you prefer you can go by car. The home includes an amazing saltwater pool and hot tub with hammocks with views of amazing palm trees.Uninterruptible power with Smart Home Energy Management Systems.

Top guest favourite
The exterior of the cabin is depicted, featuring a stone wall and a metal roof. A manicured grass area surrounds the structure, with pine trees in the background against a bright blue sky, creating a serene environment.
Cabin in Chicá
4.94 out of 5 average rating, 286 reviews

Horizonte Cabin by Casa Amaya

Take it easy at this unique and tranquil getaway at Cabaña Horizonte. Casa Amaya is a complex of 6 cabins located in Chicá de Chame, a cool climate between 18 and 24 degrees, where you can connect with nature and relax with your partner, friends or family. https://www.airbnb.com/h/miradorbycasamaya https://www.airbnb.com/h/lospinosbycasaamaya https://www.airbnb.com/h/buenavistabycasaamaya https://www.airbnb.com/h/panoramabycasaamaya We have an electric generator in case of power outages.

Guest favourite
An inviting living area features a light-colored sofa with decorative pillows and a cozy accent chair. A wall-mounted television is positioned across from the seating, while a dining table with several chairs is visible in the background. Natural light floods the space through sliding glass doors.
Flat in Chame District
4.95 out of 5 average rating, 37 reviews

Top Floor 3BR Condo Pool/Beach/ Brisas

Stylish and professionally decorated 3-bedroom top-floor condo in Playa Caracol, just steps from the beach, beach club, and Vento restaurant. Enjoy stunning pool and social area views from the expansive balcony with sitting and dining space. Perfect for families or groups, it features 2 separate entrances and a versatile lockoff suite with en suite bath and mini fridge. Includes a large living/dining area, coffee bar, and front-door parking. Close to paddle, pickleball, tennis, and more!

Superhost
The outdoor pool area is surrounded by palm trees and landscaped greenery. A spacious pool features a unique curved design, complemented by a smaller, adjacent soaking area. Lounge chairs are positioned beside the pool, inviting relaxation under the clear blue sky.
Home in Chame District
5 out of 5 average rating, 4 reviews

Country House with Pool + Billiards | Punta Chame

Welcome to our country house, ideal to disconnect from the daily bustle and enjoy the tranquility of the natural environment. Surrounded by green landscapes, it combines rustic style with nature, creating the perfect environment for an unforgettable vacation between family and friends. The house has: WiFi, CableTV, Netflix, A/A, Fanicos, Water heater, Stove,Kitchen Utencils, Refrigerator, Microwave, Oven, Coffee Maker , Airfryer and Water Dispenser. We are Pet Friendly 🐶

Superhost
A large swimming pool features clear blue water surrounded by lush palm trees. Comfortable lounge chairs are positioned nearby, offering a place to relax. The building in the background has multiple glass windows, providing a modern aesthetic to the tropical setting.
Flat in San José
4.85 out of 5 average rating, 154 reviews

B11-Tropical beach paradise, 2R/2B condo, w/pool

Disconnect for a few days from the routine. Have fun with your partner or family in our apartment in Punta Barco Viejo, we have everything you need to be comfortable and have fun in one of the most exclusive areas of the area. We have everything nearby for your best convenience, restaurants, banks, supermarkets ... I´ll deliver a personalized 5 stars attention. Oh and of course, the BEACH 5min by car!

Guest favourite
Tiny home in Altos del Maria
4.83 out of 5 average rating, 173 reviews

Arcón House

This earth-sheltered studio home offers a unique and romantic escape in the mountain of Altos del Maria. Cozy space surrounded by a lush green environment, ideal for those seeking a peaceful getaway, or an affordable stay to explore the gated community's amenities. This bunker home provides an inviting haven to unwind and disconnect from the hustle of city life.

Top guest favourite
A spacious exterior view of the loft @ Londolozi showcases a two-story structure with a red-tiled roof. Large glass doors open to a patio area with lounge chairs and a hammock, surrounded by lush greenery and mountains in the background.
Cottage in Sorá
4.95 out of 5 average rating, 116 reviews

Luxury Private Cottage in Altos del Maria

This property is situated within the gated community of Altos del Maria. Surrounded by lush forest and rivers, the loft @ Londolozi is for guests who appreciate a sense of luxury while being close to nature. While Altos del Maria enjoys a warm tropical climate, there is a cooling breeze in the mountains that is not often present in the coastal areas.

Guest favourite
A panoramic view of the serene coastline is depicted, showcasing several islands in the distance surrounded by calm waters. Luscious green hills lead towards the shore, providing a tranquil backdrop under a subtly overcast sky.
Guest suite in Panamá Oeste
4.83 out of 5 average rating, 105 reviews

Casa Buena Vista

The house is newly built within walking distance to the lookout in the Altos De Campana National Park only 45 minutes from Panama City. With absolutely stunning views it sleeps 4 to make your stay a relaxing, tranquil experience. Bring your own cooler, cook for yourself in a full complete kitchen if you like and enjoy your drinks by the pool.

Top guest favourite
A spacious living area features large windows that provide a view of the ocean. Comfortable seating options include a sectional sofa and armchairs. A round coffee table sits on a textured rug, while ceiling fans circulate air in the bright, airy space.
Apartment in Nueva Gorgona
4.95 out of 5 average rating, 201 reviews

Fabulous Beach Apartment-Ph Royal Palm-Gorgona

FIRST LINE TO THE SEA WITH DIRECT ACCESS TO THE BEACH FROM THE PH POOLS. Fabulous BEACH APARTMENT, Beach Front Unit, comfortable, unique and to relax with the family, it has 4 incredible swimming pools, jacuzzi, sauna, sports courts, board games and access to the beach and restaurant service, coming is not wanting to leave ever

Guest favourite
A pool area is visible with a clear blue pool surrounded by a concrete patio. Two lounge chairs are positioned beside the pool, and greenery from surrounding plants enhances the outdoor space. The area is framed by a shaded overhang, providing a comfortable retreat.
Home in Santa Cruz De Chinina
4.85 out of 5 average rating, 34 reviews

Country House - family Bejuco-Chame

This unique place has its own style. Suitable for celebrating birthdays, projects, working, writing and being totally at peace. Read a good book, give yourself a good pool therapy and share great moments and events with family or couple. In addition to being in an area of cultural experiences.

Guest favourite
An outdoor area features modern seating arranged around a central fire pit, surrounded by gravel and stone pathways. Elevated swings are positioned for relaxation, with a backdrop of expansive mountain views. Natural light filters through a structured canopy, enhancing the spacious feel.
Cabin in Chame District
4.86 out of 5 average rating, 135 reviews

Walk through the Clouds

Relax on this unique and quiet getaway just an hour and a half from the city. Every corner of this magical place was meticulously designed to provide the perfect escape for couples seeking intimacy, serenity, and unforgettable moments together.

Popular amenities for Santa Cruz holiday rentals

  1. Airbnb
  2. Panama
  3. Panamá Oeste
  4. Santa Cruz