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Holiday rentals in Santa Cruz

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Top-rated holiday rentals in Santa Cruz

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Guest favourite
A spacious balcony overlooks the ocean, featuring comfortable seating arrangements with a modern sofa and lounge chairs. Glass railing allows unobstructed views of the shoreline and water. Potted plants add a touch of greenery, creating a serene environment for relaxation.
Apartment in Nueva Gorgona
4.89 out of 5 average rating, 61 reviews

20th Flr Beachfront Nueva Gorgona, Panama 2/3 unit

Come and unwind in this exclusive and serene high-rise beachfront retreat also known as "My Happy Place". This is a 2 bedroom, 3 bath unit. You'll find yourself just 80 minutes away from Panama City, a location offering breathtaking sunrise and sunset views, with the beach just steps away. Indulge in modern décor that adds a touch of sophistication to your home away from home. Enjoy the soothing sounds of the waves. Immerse yourself in the calming ambiance of this remarkable beachfront condo.

Guest favourite
Flat in Coronado
4.86 out of 5 average rating, 105 reviews

Beachfront 2BR, Amazing Terrace, Jacuzzi and Views

Enjoy beautiful sunsets and the relaxing sound of the waves from your private terrace—the largest in Coronado Bay. This spacious apartment features 2 TVs and 3 AC units across the bedrooms, living, and dining areas. The main bedroom has a comfortable king bed, and the second bedroom offers one and one full bes. The fully equipped kitchen includes a stove, refrigerator, coffee maker, toaster, kettle, appliances, and a dining set for four. Comfortable, practical, and designed for a great stay.

Guest favourite
Cabin in Altos del Maria
5 out of 5 average rating, 5 reviews

Fobos – Luxury 1-Bed Cabin with Jacuzzi

Relax and enjoy Altos del María and its amenities in our brand-new tiny house. With beautiful views, a private jacuzzi, and a modern design, it truly ticks all the boxes. The house is ideal for couples (2 guests) but children are welcome (maximum 2). The kitchen is fully equipped, the bathroom features a modern design, and the bedroom is cozy and comfortable. Located on a shared lot with two others houses, this tiny house is perfect for enjoying a weekend getaway or a longer stay.

Guest favourite
A cozy cabin is illuminated at night, surrounded by lush greenery and softly glowing lights. A walkway leads to the cabin, enhancing the inviting atmosphere of the outdoor space. Stone features and landscaped areas are visible, creating a serene setting for relaxation.
Cabin in Panamá Oeste
4.82 out of 5 average rating, 358 reviews

Mirador Cabin by Casa Amaya

Casa Amaya is a cabin complex located one hour from the capital city, in Chicá de Chame, with pleasant temperatures between 18 and 24 degrees, where you can get in touch with nature and relax with your partner, friends or family. Other cabins: https://www.airbnb.com/h/lospinosbycasaamaya https://www.airbnb.com/h/buenavistabycasaamaya https://www.airbnb.com/h/panoramabycasaamaya https://www.airbnb.com/h/horizontebycasaamaya We have an electric generator in case of outages.

Guest favourite
An outdoor dining set is positioned on a spacious balcony, featuring a large wooden table surrounded by six chairs. The ocean can be seen in the background, along with palm trees swaying in the breeze. Direct beach access is visible from the balcony.
Villa in Chame
4.83 out of 5 average rating, 102 reviews

Ocean Waves Villa (C6-1D) 2 bed, 2 bath

This unique place is a fully furnished 2 bed/2 bath plus a sofa bed, second floor villa unit has breathtaking ocean views with direct beach access. The unit has a open concept living, dining & kitchen space (6 guests). Unique villa apartment over looking the picturesque Playa Caracol coast with 1km of ocean front and majestic mountain views. Playa Caracol is located on a the beach of Chame and is a newly developed area with expansion for the property and amenities.

Guest favourite
A small pool sits within a wooden deck area, surrounded by lush greenery. Steps lead from the deck to the pool, where a gentle waterfall feature adds a soothing element. Lounge chairs are positioned nearby for relaxation in a tranquil setting.
Guest house in Panamá Oeste
4.83 out of 5 average rating, 130 reviews

Mountain cabin with private pool

Enjoy peace and nature in this cozy and equipped cabin, perfect for disconnecting and relaxing. Surrounded by forests and spectacular views, here you can breathe fresh air and gaze at the stars. ✔️ Ideal for couples, families or adventurers. ✔️ Trails, rivers and viewpoints nearby. ✔️ Comfortable and equipped spaces for your comfort. - Sleeps 4 people. - Possibility of having 1 double bed and 2 single beds or 4 single beds. - Discount for two nights or more.

Superhost
A private swimming pool is set against a backdrop of vibrant sunset colors. Water features provide gentle splashes, and green plants outline the pool area. The modern house with large windows is visible in the background, blending with the natural surroundings.
Cottage in Panamá Oeste
4.82 out of 5 average rating, 188 reviews

Santa Fe de Lajas Chame, Panama.

Santa Fe de Lajas in Chame, Province of West Panama, a vacation home that allows you to connect with nature and spend leisure time alone or with family. The house has a capacity for 10 people. It has three bedrooms, each with its own private bathroom. Kitchen, living room, dining room, a room to work, pool, covered terrace, outdoor garden and BBQ area. Wi-Fi and TV services. Access to the area's beaches, shopping centers, mountains, etc.

Top guest favourite
Flat in Chame, Panama
5 out of 5 average rating, 8 reviews

24-hour ocean view in Coronado

Relax in this quiet and elegant space. You can walk to the beach, and you can go to eat a delicious dinner or lunch at nearby restaurants. If you want to go to the gym, we have all the equipment. Go and enjoy the pool, which is lovely and large for swimming. We have ping-pong tables, a pool table, a recreation area, and you have a workspace, and a refreshing view of the sea. We have a room with a queen size bed and a sofa bed.

Top guest favourite
Camper van/Motorhome in El Valle de Antón
4.99 out of 5 average rating, 251 reviews

Armadillo Shelter & Garden Valle de Anton

It is a unique and special accommodation that we have designed for you to experience the Anton Valley in a more conscious and natural way. It's a remodeled RV or trailer, to make it cozy>functional and comfortable>tiny house style. The space has a small and complete kitchen, hot water, Wi-Fi, coffee and tea. It is surrounded by a nice garden. With a separate entrance and an area to park the car. Ideal for 1-2 people.

Top guest favourite
The modern two-story cabin features large glass windows that offer expansive views of the surrounding greenery. A spacious deck with seating is visible, surrounded by lush vegetation and natural stone pathways leading up to the entrance.
Cabin in Panamá Oeste
4.9 out of 5 average rating, 190 reviews

Altos del María Cabin La Loma de Styria

Relax with the whole family at this peaceful place to stay. It is a fantastic, cool and pleasant place where you can do many ecotourism activities, the best option if you want to have one of the best views you can imagine. Great for couples too. We have 2 bedrooms on the 2nd floor and 2 bathrooms. Multiple places to take beautiful photographs

Guest favourite
Home in San José
5 out of 5 average rating, 11 reviews

Family Paradise | Pool, Jacuzzi & Garden

Escápate a esta exclusiva villa en Punta Barco, dentro de una urbanización privada. Disfruta piscina y jacuzzi privados, amplias terrazas, un enorme jardin y 4 elegantes recámaras. Perfecta para familias o grupos que buscan lujo, privacidad y cercanía a la playa. El terreno de esta villa es totalmente cercado.

Top guest favourite
A spacious bed is dressed in a colorful quilt, complementing an inviting orange pillow. Large glass doors offer a panoramic view of the surrounding mountains and lead to a private outdoor space with a swimming pool.
Tiny home in Panamá
4.97 out of 5 average rating, 232 reviews

Mountain cabin in Altos del María

The cabin in Altos del María is located in the heart of the mountain, with beautiful landscapes, trees, animals, monkeys, birds, just minutes from picnic areas, outdoor games, river, waterfall, trails and viewpoints. Escape into nature! Close to everything, away from the daily grind!

Popular amenities for Santa Cruz holiday rentals

  1. Airbnb
  2. Panama
  3. Panamá Oeste
  4. Santa Cruz