Apartment holiday rentals in Cape Girardeau

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Top-rated apartment rentals in Cape Girardeau

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Top guest favourite
A view from the front porch showcases a vibrant autumn scene, with trees covered in golden leaves. A cozy seating area is visible, framed by white railings, and a peaceful street with fallen leaves creates a calm atmosphere.
Flat in Cape Girardeau
4.98 out of 5 average rating, 444 reviews

Beautiful Historic Boulevard District Apartment

This beautiful, private upstairs apartment is located on a favorite street in Cape Girardeau’s Historic Boulevard District. It is walking distance to SEMO University, Capaha Park, and the downtown riverfront. Recently remodeled for laundry, spacious rooms offer private bedroom spaces and a cozy den for watching movies or reading. The kitchen is fully equipped with amenities. This quiet neighborhood setting even has a front porch swing and sitting area where you can enjoy your morning coffee.

Top guest favourite
A spacious living area features large windows allowing natural light to fill the space. A comfortable grey sofa is paired with a unique coffee table, while stylish dining chairs surround a white table. The kitchen area includes modern appliances and cabinetry.
Flat in Cape Girardeau
4.95 out of 5 average rating, 279 reviews

Brand new 2 bedroom unit right in downtown Cape.

This special place is close to everything, making it easy to plan your visit. Walking distance to restaurants, the river and nightlife. Property includes wifi, full kitchen, laundry, deck and private parking for one. One king bed room and a twin bed room in addition to a roll out twin bed along with a 60 inch smart television. Dog bed and bowls included along with board games! Property is conveniently located across the street from "The Bar" the famous spot from the movie "Gone Girl" .

Top guest favourite
A view from above captures the full kitchen equipped with electric appliances, including a refrigerator and stovetop. The wooden floor is complemented by colorful area rugs, and natural light brightens the space. Shelves and cabinetry are neatly arranged in the background.
Flat in Carbondale
4.95 out of 5 average rating, 63 reviews

Regal Rustic Retreat

Take it easy at this unique and tranquil getaway. Close to SIU Carbondale and also Murphysboro. We offer a quiet, simple apartment to relax and recharge. Free local over the air television. We have broadband/smart monitor for your HDMI stick . Bring your own Roku or Firestick with your subscriptions. The second bedroom is an open loft area, not a separate room. We offer a large storage space for bicycles and mudroom with washer/dryer for cleaning up after a hike or bike race. Full kitchen.

Top guest favourite
The building features classic brick architecture with ornate ironwork detailing on the balcony. A large clock is positioned on the exterior wall. Nearby streets and parked vehicles are visible, along with a clear blue sky providing a bright backdrop.
Flat in Cape Girardeau
4.98 out of 5 average rating, 103 reviews

Historical Kage House

The Building is reminiscent of eighteenth-century New Orleans architecture, and was built sometime before 1883. The Kage House is located at 120 Broadway in the historical district and is less than a minutes walk to Main Street and less than a 10 minutes walk to the Isle of Capri Casino. On Main Street you will find many fine shops and restaurants, or just enjoy the scenic area as you walkabout. This is by far one of the best places in Cape. Additional reviews can be read on the VRBO website.

Guest favourite
A serene view of the Mississippi River is presented, highlighting the tranquil water and the pavilion that juts into the river. Lush green grass borders the water, and trees line the distant shore, creating a natural landscape under a clear sky.
Flat in Scott City
4.96 out of 5 average rating, 48 reviews

RiverSide Barn Suite on the Mississippi River.

The barn suite is a beautiful 2 bedroom apartment overlooking the Mississippi River and housed in a unique barn with its own separate entrance. The deck views are spectacular and takes sitting and relaxing to a new level. Our wine place “The RiverHouse “ is within walking distance with the best worldwide wines and menu in the area. www.theriverhousewineplace.com We are 12 minutes from Cape Girardeau and serviced by Lyft & Car-Go. You May contact us by text or call and available at any time.

Guest favourite
A cozy bedroom is presented with wooden walls, featuring a spacious bed adorned with a patterned quilt. Small sitting area includes a table with two chairs. A window allows natural light, complemented by decorative elements on the walls.
Flat in Murphysboro
4.89 out of 5 average rating, 62 reviews

The Windbreak

Forget your worries in this spacious apartment, the lower/first level of a 3-level house, a peaceful place at the woodsy end of a country lane, not far from two state parks, five lakes, wine trail, Southern Illinois University and other interesting features of this area. The 1st level apartment is large, has a kitchen, dining room, 2 bedrooms, living room/bedroom, a full bath, and a utility room, 2 exterior doors, one to a patio with a fire pit and charcoal cooker.

Guest favourite
A spacious living area features dark hardwood floors and light gray walls, accented by a comfortable leather sofa and an elegant coffee table. Artwork adorns the walls, and natural light streams in from the nearby windows, illuminating the inviting space.
Flat in Cape Girardeau
4.92 out of 5 average rating, 51 reviews

Downtown 4BR with 2 King Beds! Off-street parking

- Massive two story 2,400 sq ft historic apartment on Broadway - Recently renovated - Downtown location - Free off-street parking - Walking distance to SEMO and River Front - 2 King beds! - 3 Bathrooms - 2 futons and one couch for extra sleepers - Self check-in with smart lock - Full kitchen - Washer/Dryer included - Formal dining area - Second cozy living room upstairs - Room darkening shades in all bedrooms - Note: narrow staircase at entrance

Top guest favourite
A bright living area features a yellow sofa adorned with leafy cushions, positioned on a circular rug. The open floor plan reveals a modern kitchen with dark appliances and cabinetry, as well as a dining area designed for two. Natural light enters through a nearby window.
Flat in Carbondale
4.94 out of 5 average rating, 33 reviews

Urban-Chic King Suite Near SIU Carbondale

Stay at Suite 1, Wall Street Suites — an urban-chic king suite near SIU Carbondale. Once the city’s water department, this renovated space features stylish decor, full kitchen, Smart TV & modern bath. Guests enjoy shared lobby workspace & seating. Perfect for monthly or mid-term stays, it’s just steps from SIU East Campus — where historic character meets modern comfort in the heart of Carbondale.

Top guest favourite
A cozy living area is furnished with two spacious brown reclining sofas, positioned around a soft area rug. A side table is visible, with a small decorative item placed on it. Natural light enters through a window covered by white blinds.
Flat in Marble Hill
4.96 out of 5 average rating, 55 reviews

Lovely 2 bedroom apartment with luxury shower.

This special home away from home has 800 sq. ft. and is on 1st floor. Less than one mile from grocery, a few eateries and park. There is little traffic on our one-block street with an old graveyard across the street. We are just minutes away from a beautiful lake and rivers. Explore historic sites, visit antique shops and enjoy fishing, kayaking, hunting, visiting family or just relaxing.

Superhost
The living room features comfortable seating for four and a bay window providing natural light. A SmartTV is mounted on the wall, with a cozy fireplace ambiance displayed. Decorative plants and framed artwork enhance the welcoming environment, inviting relaxation.
Flat in Cape Girardeau
4.8 out of 5 average rating, 5 reviews

Rivers Dawn- Historic Home - River View - King Bed

This cozy upstairs loft is just steps from Downtown Cape Girardeau, offering stunning views of the Mississippi River, Bill Emerson Memorial Bridge, and historic district homes. Enjoy peace and quiet, with the vibrancy of downtown just a short walk away. Perfect for those seeking a relaxing retreat with easy access to the area's best attractions. Ideal for both relaxation and exploration!

Superhost
Flat in Cape Girardeau
4.56 out of 5 average rating, 9 reviews

Urban 2BR 2BTH Chic Apartment

Stay in the heart of Downtown Cape Girardeau in this beautifully remodeled apartment. Inside, you’ll find a bright, open layout with stylish finishes, modern comforts, and gorgeous natural light throughout. And be sure to check out Roni’s Mac Bar just down the street—home of the viral mac & cheese everyone can’t stop raving about!

Guest favourite
The exterior of a two-story home is shown, featuring a combination of brick and siding. A covered porch is located at the front, and large windows are visible. Lush green grass surrounds the house, with trees providing shade and a peaceful atmosphere.
Flat in Oak Ridge
4.86 out of 5 average rating, 28 reviews

The Teal Door

Relax with the whole family at this peaceful place to stay. All on one level, no steps. Property is 5 years old and very clean. Just 3 miles west of I-55 exit 111. Only 20 minutes from Cape, Jackson or Perryville but still has country charm. Places to dine within 10 minutes. Local cafe next door for quick lunch or dinner.

Popular amenities for Cape Girardeau apartment rentals

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Avg. price$159 SGD$144 SGD$147 SGD$162 SGD$168 SGD$168 SGD$169 SGD$168 SGD$155 SGD$153 SGD$161 SGD$144 SGD
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Quick stats about flat rentals in Cape Girardeau

  • Total holiday rentals

    Explore 40 holiday rentals in Cape Girardeau

  • Nightly prices starting at

    Cape Girardeau holiday rentals start at $52 SGD per night before taxes and fees

  • Verified guest reviews

    Over 2,320 verified reviews to help you choose

  • Family-friendly holiday rentals

    20 properties offer extra space & child-friendly amenities

  • Pet-friendly holiday rentals

    Find 10 rentals that welcome pets

  • Rentals with dedicated workspaces

    30 properties have a dedicated workspace

  • Wifi availability

    40 of Cape Girardeau holiday rentals include wifi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi and Pool across Cape Girardeau rentals

  • 4.8 Average rating

    Cape Girardeau stays are highly rated by guests – averaging 4.8 out of 5!