
Apartment holiday rentals in Cape Girardeau
Find and book unique apartments on Airbnb
Top-rated apartment rentals in Cape Girardeau
Guests agree: these apartments are highly rated for location, cleanliness and more.

Priv 1br1ba Floor: Nurse & SEMO campus Friendly
Catering to nurses/travel professionals. Very short walk to SEMO Campus. Close to everything when you stay at this centrally-located 1bed-1bath apartment, located just down the street from Mercy Hospital. You are a quick walk away to the park's walking path, Kidds convenience store, and many locally owned restaurants. You are also a quick walk from SEMO Houck Field House for football games and the Cape Catfish prospect league baseball field at Capaha Park! Host is a Licensed Real Estate Agent

Beautiful Historic Boulevard District Apartment
This beautiful, private upstairs apartment is located on a favorite street in Cape Girardeau’s Historic Boulevard District. It is walking distance to SEMO University, Capaha Park, and the downtown riverfront. Recently remodeled for laundry, spacious rooms offer private bedroom spaces and a cozy den for watching movies or reading. The kitchen is fully equipped with amenities. This quiet neighborhood setting even has a front porch swing and sitting area where you can enjoy your morning coffee.

Brand new 2 bedroom unit right in downtown Cape.
This special place is close to everything, making it easy to plan your visit. Walking distance to restaurants, the river and nightlife. Property includes wifi, full kitchen, laundry, deck and private parking for one. One king bed room and a twin bed room in addition to a roll out twin bed along with a 60 inch smart television. Dog bed and bowls included along with board games! Property is conveniently located across the street from "The Bar" the famous spot from the movie "Gone Girl" .

Historical Kage House
The Building is reminiscent of eighteenth-century New Orleans architecture, and was built sometime before 1883. The Kage House is located at 120 Broadway in the historical district and is less than a minutes walk to Main Street and less than a 10 minutes walk to the Isle of Capri Casino. On Main Street you will find many fine shops and restaurants, or just enjoy the scenic area as you walkabout. This is by far one of the best places in Cape. Additional reviews can be read on the VRBO website.

Unique Design | Walk Downtown/River | .5 mile SEMO
At our Adventurous 2 Bedroom Suite you’ll first arrive at a Brightly decorated Space with Artsy Walls and Bold Decor. Designed with its History in mind & a twist of Creativity, you will Immerse Yourself within your Stay; from our Stocked Kitchen, Reading Area with Indoor Swing to Themed & Cozy Bedrooms. Enjoy being near Downtown/the River with a short Bike Ride or Walk and when you are ready to Tuck in at night, Sink into our 10” Memory Foam mattress with Plush Pillows and feel at Ease.

Downtown Penthouse w/ Amazing River View!
AMAZING RIVERVIEW Plus Close to Downtown Cape? Our Airbnb is the best place to be! Relax in our Roof Deck after going around downtown and ENJOY THE VIEW. Located in a safe and quiet neighborhood plus it is WALKING DISTANCE from everything! It features a roof deck with (by far) the best view in Cape, enough space for six to sleep (two queen beds and two couches), one off street parking spot and a building with secure entry. Plus we just live across the street if you need anything.

The Outlook - Private Balcony
Welcome to 115 N Water, Unit 103 in Cape Girardeau, MO! This delightful property not only offers a cozy retreat but also boasts a private balcony with stunning, unobstructed views of the Mighty Mississippi River. Perfectly situated close to downtown, it's just steps away from a vibrant nightlife scene, with numerous bars and restaurants for an unforgettable date night experience. Enjoy the best of both worlds – scenic beauty and lively entertainment – right at your doorstep!

Visit the "Gone Girl" neighborhood
Living rm/bedrm, full kitchen, ADA bath, and walk in closet. Fully equipped with dishes,linens, refig, micro,stove, keurig, dishwasher and welcome home snacks. Double Murphy bed, queen hide a bed couch convert the living room to bedroom. Space is good for up to 3 adults, 2 adults and 2 children or a single guest. We accept well mannered dogs up to 50 pounds. We do not accept CATS. Like cats but they cause additional clean up. See pets section for dog guest guidelines.

Fresh & Cozy Retreat w/ King Bed · By KeenStays
This fresh apartment offers a unique blend of chic style and cultural charm, nestled in a freshly rehabilitated building in Downtown Cape Girardeau. Enjoy a vibrant stay by being in walking distance to shopping, dining, and downtown entertainment! The apartment features a spacious, light-filled layout with chic finishes and appliances. Enjoy a comfortable & spacious living area. Don't forget to visit the viral mac & cheese bar, Roni's Mac Bar, downstairs!

Downtown 4BR with 2 King Beds! Off-street parking
- Massive two story 2,400 sq ft historic apartment on Broadway - Recently renovated - Downtown location - Free off-street parking - Walking distance to SEMO and River Front - 2 King beds! - 3 Bathrooms - 2 futons and one couch for extra sleepers - Self check-in with smart lock - Full kitchen - Washer/Dryer included - Formal dining area - Second cozy living room upstairs - Room darkening shades in all bedrooms - Note: narrow staircase at entrance

Downtown Cape 2 Bdrm/2 Bath Apt | Cozy & Walkable
Experience style and convenience in this new, cozy, fully outfitted central apartment. Enjoy your privacy while being right in the heart of downtown Cape Girardeau! You’ll be seconds away from great restaurants, bars, shops, and more! A great stay for both short-term and mid-term stays! - King-size bed - Dedicated workspace + highspeed wifi - Fully equipped kitchen - Laundry machine in unit - Free parking - Walkable area, near trails and park

Rivers Dawn- Historic Home - River View - King Bed
This cozy upstairs loft is just steps from Downtown Cape Girardeau, offering stunning views of the Mississippi River, Bill Emerson Memorial Bridge, and historic district homes. Enjoy peace and quiet, with the vibrancy of downtown just a short walk away. Perfect for those seeking a relaxing retreat with easy access to the area's best attractions. Ideal for both relaxation and exploration!
Popular amenities for Cape Girardeau apartment rentals
Weekly apartment rentals

Private Nurse Retreat 2 + Walk to SEMO Activities!

2Bdrm Stay in Downtown Cape | Walkable, Laundry

Private Nurse Retreat 2br-1ba

The Plum Door

Art Deco Downtown Loft 2BR 1BTH Apartment

Modern Boho Getaway · 1BR Apartment · By KeenStays
Private apartment rentals

Fresh & Cozy Retreat w/ King Bed · By KeenStays

Downtown 4BR with 2 King Beds! Off-street parking

Downtown Loft 1 on Main

Modern 2BR Apt w Electric Fireplace · By KeenStays

Unique Design | Walk Downtown/River | .5 mile SEMO

Brand new 2 bedroom unit right in downtown Cape.

Downtown Penthouse w/ Amazing River View!

Private Downtown Apartment
Family-friendly apartment rentals

Fresh & Cozy Retreat w/ King Bed · By KeenStays

Cabin in the woods perfect for hiking

Modern 2BR Apt w Electric Fireplace · By KeenStays

Downtown 4BR with 2 King Beds! Off-street parking

Unique Design | Walk Downtown/River | .5 mile SEMO

Brand new 2 bedroom unit right in downtown Cape.

Downtown Penthouse w/ Amazing River View!

Private Downtown Apartment
When is the best time to visit Cape Girardeau?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | $161 SGD | $146 SGD | $149 SGD | $165 SGD | $170 SGD | $170 SGD | $171 SGD | $170 SGD | $157 SGD | $155 SGD | $163 SGD | $146 SGD |
| Avg. temp | 1°C | 4°C | 9°C | 14°C | 20°C | 25°C | 26°C | 25°C | 21°C | 15°C | 8°C | 3°C |
Quick stats about flat rentals in Cape Girardeau

Total holiday rentals
Explore 30 holiday rentals in Cape Girardeau

Nightly prices starting at
Cape Girardeau holiday rentals start at $52 SGD per night before taxes and fees

Verified guest reviews
Over 2,350 verified reviews to help you choose

Family-friendly holiday rentals
20 properties offer extra space & child-friendly amenities

Pet-friendly holiday rentals
Find 10 rentals that welcome pets

Rentals with dedicated workspaces
20 properties have a dedicated workspace

Wifi availability
30 of Cape Girardeau holiday rentals include wifi access

Popular amenities for guests
Guests love Kitchen, Wifi and Pool across Cape Girardeau rentals

4.9 Average rating
Cape Girardeau stays are highly rated by guests – averaging 4.9 out of 5!
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