Pet-friendly holiday rentals in Cape Girardeau

4.94 out of 5 average rating, 177 reviews

The geodesic dome is illuminated warmly from within, creating a welcoming glow against the night sky. The structure's unique shape and large window reveal a glimpse of the cozy interior, showcasing a serene space ideal for relaxation and connection with nature.

Dome in Perryville

The Snow Globe*OffGrid DomeGLAMP*Adventurers Only

EXPERIENCE The Dome in the Woods • IMMERSE in complete silence with the absence of electricity: no hum or vibrations from this completely solar/propane fueled geodesic dome. NoAC • GLAMP in this OFF GRID ADVENTURE. 430 sq ft floor plan. 14 ft ceiling. 20 ft bay window with endless nature view at the foot of your bed. Lofted 7ft. • STARGAZE from the deck or fire pit • NESTLE in the romantic wooded nature of southeast MO. S of St Louis.N of Memphis • UNPLUG, UNWIND, RELAX. Adventure seekers only!

4.97 out of 5 average rating, 114 reviews

Cabin in Carbondale

Beautiful Cabin close to SIU/wineries/Shawnee

Beautiful cabin sitting in the middle of woods w/ a large entertaining deck that makes you feel like are " away from it all" even though you are 3 mins away from SIU! Features 4 bedrooms & 2 full baths with an open floor plan with plenty of room for family and friends! Enjoy the large deck to grill or to just enjoy a glass of wine from one of our local wineries. Large master suite with jacuzzi tub to unwind. Make use of the concrete party pad with firepit & bar/ game room. Location is perfect!

4.95 out of 5 average rating, 320 reviews

A spacious living area features large windows allowing natural light to fill the space. A comfortable grey sofa is paired with a unique coffee table, while stylish dining chairs surround a white table. The kitchen area includes modern appliances and cabinetry.

Flat in Cape Girardeau

Brand new 2 bedroom unit right in downtown Cape.

This special place is close to everything, making it easy to plan your visit. Walking distance to restaurants, the river and nightlife. Property includes wifi, full kitchen, laundry, deck and private parking for one. One king bed room and a twin bed room in addition to a roll out twin bed along with a 60 inch smart television. Dog bed and bowls included along with board games! Property is conveniently located across the street from "The Bar" the famous spot from the movie "Gone Girl" .

4.98 out of 5 average rating, 173 reviews

A cozy living area is presented, featuring a stone fireplace with a mounted television above. Comfortable seating options include a leather armchair and a soft couch, arranged around a wooden coffee table. Natural light filters in through the window, enhancing the tranquil environment.

Cabin in Makanda

Sanctuary Cabin- Hot Tub & Woods

Hi, hello, welcome! We invite you to take it easy at this unique and tranquil getaway. The kitchen is stocked, the hot tub is ready to go, and the local area boasts many wineries, state parks for hiking, and beautiful scenery. This spacious cabin features a comfortable King bed, 55” TV above a gas fireplace, and recently had a top to bottom renovation! The spacious back deck features a large hot tub just steps from the back door, hooks for the provided terry cloth robes, and a Weber grill.

4.95 out of 5 average rating, 103 reviews

A charming exterior view of a blue house is presented, featuring white trim and multiple windows. A covered porch area includes two red chairs and a black barbecue grill. Flower beds with plants are positioned along the front, set against a gravel area and surrounding greenery.

Home in Cobden

Wine trail cozy cabin! Hot Tub!

Beautiful home on the wine trail. Explore the Shawnee National Forest, Little Grand Canyon and Panoma Natural Bridge. See Giant City State Park. Enjoy near by wineries/orchards Close to Cedar Lake where you can swim or fish. Then relax in the quiet, peaceful setting. This home has been completely renovated with two bedrooms both with queen beds. A full bathroom and a spacious kitchen with everything you will need! Deck over looks 20 wooded acres with a wonderful hot tub. Pet friendly

5.0 out of 5 average rating, 716 reviews

The treehouse structure is elevated, supported by stilts, with large windows that reflect the surrounding greenery. The exterior features a combination of wood finishes, and warm lighting casts a welcoming glow in the evening. The pathway leads through the natural landscape to the entrance.

Treehouse in Perryville

Private Treehouse Retreat | Hot tub

The TreeLoft is the first of two treehouses at BaseCamp—designed for cozy seclusion, romance, and rest. Nestled in a private forest just 1 hour from St. Louis, it blends upscale comfort with immersive nature, while still being 20–35 minutes from hiking, wineries, and dining. ✨Our NEW treehouse, The TreeRise, offers an even more elevated, spacious experience at BaseCamp. Perfect for romantic getaways, anniversaries, personal retreats, and intentional escapes to unplug and reconnect.

4.94 out of 5 average rating, 281 reviews

A modern farmhouse is depicted at sunset, featuring a welcoming entrance with a covered porch. A stone pathway leads to the front door, bordered by a grassy lawn that extends to fields and trees in the background.

Barn in Cape Girardeau

Under the Stars - Farmhouse

Enjoy the tranquility of this modern farmhouse charmer! Custom built minutes from downtown Cape. Relax outside around the fire pit, roast marshmallows and watch the sunset. Finish the night with a long soak in the hot tub. Start the morning on the front porch rocking chairs and take in a sunrise. Open concept, fully equipped kitchen, 3 Bd. including King master/full bath, 2 Queens with full guest bath. Near Trail of Tears and walking distance to classic dive bar/burger joint

4.95 out of 5 average rating, 341 reviews

A rustic cottage is nestled among tall trees, showcasing a natural setting during autumn. Colorful fall foliage blends with the greenery, while fallen leaves cover the ground. The warm tones of the cottage complement the serene landscape.

Place to stay in Cobden

Cobden Retreat in the Woods

Eva’s Roost Retreat Cabin is located at Center For Lost Arts near Cobden, Illinois. Uniquely crafted rustic, zen-style cottage, designed to be close to the earth & nature. Extensive, curtainless windows facing the forest & pond allow for private views: sunrise, moonrise, forest & wildlife. Yoga mat, guitar & some art supplies. Personal outdoor space with firepit & comfy adirondack chairs. Entrance to wandering trails right outside your back door. Perfect place to retreat and renew.

4.92 out of 5 average rating, 183 reviews

Home in Cape Girardeau

College town Charm: Minutes from Downtown Cape

EXCELLENT LOCATION near downtown riverfront Cape! Enjoy live music, local dining/coffee, shopping, casino, and seasonal steamboat rides downtown. Less than 5 min. from Southeast Missouri State University & Southeast Hospital. Centrally located near wedding venues: Rusted Route, Deerfield, Watersedge, Sweet Pecan, and Country Club. 2 blocks from scenic Capaha Park. Home to Capaha baseball. This huge park includes play structures, basketball court, disc golf & fishing pond.

4.85 out of 5 average rating, 143 reviews

A charming duplex exterior is shown, featuring a red wooden facade with a light brown roof. Flower pots line the front, and multiple windows allow natural light. A gravel driveway leads to the entrance, with a satellite dish mounted on the roof.

Home in Makanda

Cedar Lake Retreat A

Enjoy a quiet, peaceful, pet-friendly retreat, less than a mile from Cedar Lake boat ramp/kayak launch and Poplar Camp Beach. This cute and comfy duplex is less than 6 miles from Giant City State Park, located in Shawnee National Forest, and just 4 miles from Southern Illinois University-Carbondale. Enjoy fishing, kayaking, and rock-climbing, or hit the Shawnee Wine Trails. If you’re a nature buff or you’re in town for SIU festivities, this is the place for you.

4.87 out of 5 average rating, 331 reviews

A cozy living area is furnished with a large sectional sofa and a matching armchair, complemented by decorative cushions. Light filters through window blinds, and a soft area rug covers the hardwood floor. A small table is positioned nearby.

Home in Carbondale

Relaxing 3 Bedroom Cottage in Quiet Neighborhood

This happy 3 bedroom duplex will be a family favorite on your next trip to Southern Illinois. You'll enjoy 3 cozy bedrooms each equipped with a TV, 1 bathroom, ample deck space and firepit. We are located on a quiet street within walking distance of all Carbondale has to offer – Downtown Carbondale, restaurants and pubs (.8 miles), the Memorial Hospital of Carbondale (.5 miles), Carbondale Civic Center (.8 miles), Amtrak Station (.9 miles), and SIU (1.1 miles).

4.97 out of 5 average rating, 335 reviews

A spacious living area features exposed brick walls and original wood floors. Large windows provide natural light, while a comfortable sofa and dining table accommodate relaxation and meals. An area rug adds color, and modern lighting enhances the inviting atmosphere.

Loft in Perryville

Downtown Urban Loft #9 – Above Mary Jane Burgers

Downtown Perryville, MO. Pet-friendly loft directly above Mary Jane Burgers & Brew on the Historic Square, steps from restaurants, bars, shops, coffee spots, and local attractions. Features exposed brick, original wood floors, a California King bed with blackout shades, spa shower for two, large soaker tub, open kitchen, comfortable living area, and large TV. Guests have the entire space. Easy walking, parking, and access to downtown events.

Popular amenities for Cape Girardeau pet-friendly home rentals

Kitchen

Wifi

Pool

Free parking on premises

Air conditioning

Pet-friendly house rentals

4.89 out of 5 average rating, 28 reviews

Home in Cape Girardeau

The Brick Home

4.91 out of 5 average rating, 43 reviews

A single-story house with a red roof and brick facade is nestled among tall trees, providing shade. The home is situated on a gentle slope covered with green grass, creating a serene outdoor setting with ample space surrounding it.

Home in Jackson

Rural Comfort in Fruitland

4.94 out of 5 average rating, 34 reviews

The exterior of a charming brick house is presented, surrounded by manicured green grass and shrubs. Large windows invite natural light, while the roof features a small chimney. A clear blue sky and scattered clouds create a pleasant backdrop to the home.

Home in Cape Girardeau

Located near downtown and casino. Dog friendly

5.0 out of 5 average rating, 23 reviews

The Victorian-style house showcases a gray exterior with white trim and a turret. A wide porch welcomes guests, adorned with bright flowers and greenery. Warm light spills from the windows, highlighting the inviting entrance against a backdrop of a colorful sunset.

Home in Anna

Magical Victorian near hiking / wine trail

4.92 out of 5 average rating, 38 reviews

A covered porch features a round table surrounded by chairs and two spacious Adirondack chairs. Soft lighting is provided by string lights and a lantern that rests on the table, creating a cozy setting against the backdrop of a twilight sky.

Home in Pomona

Shawnee Forest Vacation Lodge

4.98 out of 5 average rating, 43 reviews

A charming house is presented with a dark exterior and a peaked roof. Steps lead to the entrance, flanked by two large windows that allow natural light to fill the interior. Lush green grass surrounds the property, providing a welcoming atmosphere.

Home in Advance

2 King,2 Twin,1 Futon House

4.88 out of 5 average rating, 41 reviews

Home in Altenburg

Historic House in the heart of Altenburg

4.96 out of 5 average rating, 55 reviews

Home in Anna

Updated Farmhouse w/ King Suite

Pet-friendly home rentals with a pool

Guest house in Carbondale

A wooden Japanese Ofuro soaking tub is illuminated by soft ambient lighting. Two individuals relax with their feet visible, surrounded by lush greenery and colorful garden lights. A glass of wine rests within reach, enhancing the serene ambiance.

Carbondale Pool House - Sauna, Hot Tub, Dogs OK

4.99 out of 5 average rating, 282 reviews

5.0 out of 5 average rating, 55 reviews

The cabin features a welcoming entrance with a ramp and wooden deck, surrounded by a natural landscape. The exterior is constructed from warm-toned logs, complemented by a green roof and large windows providing plenty of natural light.

Cabin in Sedgewickville

Cozy Country Cabin

A cozy cabin is set amongst trees, featuring a wooden porch with steps leading up to a welcoming entrance. Large windows with shutters allow natural light to brighten the interior. The earthy tones of the wooden exterior blend harmoniously with the surrounding nature.

5.0 out of 5 average rating, 7 reviews

Black Bear Cabin K03A

A rustic cabin entrance is framed by wooden logs, featuring a simple porch with a swing. A single door is adorned with a number, while a window allows natural light to enter the space. Lush greenery surrounds the cabin for a tranquil setting.

4.92 out of 5 average rating, 12 reviews

Rustic Bass Cabin KK3

A rustic cabin features a sloped roof with green metal sheeting and natural wood siding. A spacious front porch is supported by large wooden logs and includes a comfortable swing. A picnic table is positioned nearby, surrounded by gravel landscaping.

4.75 out of 5 average rating, 12 reviews

Catfish Cabin KK4

A wooden cabin features a welcoming front porch with steps leading up to a white door. Two windows flank the door, allowing natural light inside. The exterior showcases a rustic design with wood paneling and stone accents at the base.

5.0 out of 5 average rating, 4 reviews

Racoon Cabin D09

A wooden cabin with a green metal roof is surrounded by trees. The porch features rustic railings and a picnic table. Stairs lead to the entrance, while stone accents add a natural touch to the foundation.

Coyote Cabin F09

Private, pet-friendly home rentals

4.95 out of 5 average rating, 78 reviews

The spacious living area features a comfortable couch and a coffee table, while a set of three barstools accompanies a sleek dining table. Natural light streams through multiple windows, highlighting the wood flooring and modern kitchen appliances in the background.

Tiny home in Jackson

The Cottage, Rusted Route Farms

4.88 out of 5 average rating, 8 reviews

Flat in Cape Girardeau

Riverwalk 2BR | Easy, Walkable Stay

4.95 out of 5 average rating, 88 reviews

An open living space features a kitchen area with modern appliances and a dining table surrounded by chairs. Pendant lights hang from the ceiling, illuminating a cozy seating area with plush sofas. A rustic wooden table is placed against the wall, enhancing the room's charm.

Cabin in Jackson

The Cabin at Timber Creek

4.91 out of 5 average rating, 47 reviews

Farm stay in Jackson

The Cabins 1

Tiny home in Cape Girardeau

A-Frame @ Inspiration Village on Boulder Creek

4.98 out of 5 average rating, 49 reviews

4.96 out of 5 average rating, 53 reviews

A serene view of the Mississippi River is presented, highlighting the tranquil water and the pavilion that juts into the river. Lush green grass borders the water, and trees line the distant shore, creating a natural landscape under a clear sky.

Flat in Scott City

RiverSide Barn Suite on the Mississippi River.

4.93 out of 5 average rating, 57 reviews

The cottage exterior features a welcoming porch with wooden railings and an American flag. Lush green shrubs and flower pots create a well-maintained landscape. The surrounding trees provide a natural backdrop, while the sunlight illuminates the cottage's inviting facade.

Cottage in Cobden

The Cobden Cottage - A Soul Refreshing Getaway