Pet-friendly holiday rentals in Cape Girardeau

Find and book unique pet-friendly homes on Airbnb

Quick stats about holiday rentals that are pet-friendly in Cape Girardeau

  • Total holiday rentals

    Explore 40 holiday rentals in Cape Girardeau

  • Nightly prices starting at

    Cape Girardeau holiday rentals start at $52 SGD per night before taxes and fees

  • Verified guest reviews

    Over 3,520 verified reviews to help you choose

  • Family-friendly holiday rentals

    20 properties offer extra space & child-friendly amenities

  • Rentals with dedicated workspaces

    20 properties have a dedicated workspace

  • Wifi availability

    40 of Cape Girardeau holiday rentals include wifi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi and Pool across Cape Girardeau rentals

  • 4.8 Average rating

    Cape Girardeau stays are highly rated by guests – averaging 4.8 out of 5!

Top-rated pet-friendly home rentals in Cape Girardeau

Guests agree: these pet-friendly homes are highly rated for location, cleanliness and more.

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Top guest favourite
A spacious living area features exposed brick walls and original wood floors. Large windows provide natural light, while a comfortable sofa and dining table accommodate relaxation and meals. An area rug adds color, and modern lighting enhances the inviting atmosphere.
Loft in Perryville
4.97 out of 5 average rating, 330 reviews

Downtown Loft Amazing Bath Tub & Shower

Downtown Perryville, MO **DISCLAIMER** you will hear restaurant chatter & music if you do not have a tv/or radio playing between the hours of 10:30am & 1:30am. If you go to bed early I recommend headphones, ear plugs or play nature sounds on Alexa. This is a pet friendly loft apartment so I would not recommend if you are allergic to dogs or cats. This apartment is located above one of the most popular destination restaurant's around "Mary Jane Burgers & Brew" on the Downtown Historic Square.

Guest favourite
The geodesic dome is illuminated warmly from within, creating a welcoming glow against the night sky. The structure's unique shape and large window reveal a glimpse of the cozy interior, showcasing a serene space ideal for relaxation and connection with nature.
Dome in Perryville
4.94 out of 5 average rating, 169 reviews

The Snow Globe*OffGrid DomeGLAMP*Adventurers Only

EXPERIENCE The Dome in the Woods • IMMERSE in complete silence with the absence of electricity: no hum or vibrations from this completely solar/propane fueled geodesic dome. NoAC • GLAMP in this OFF GRID ADVENTURE. 430 sq ft floor plan. 14 ft ceiling. 20 ft bay window with endless nature view at the foot of your bed. Lofted 7ft. • STARGAZE from the deck or fire pit • NESTLE in the romantic wooded nature of southeast MO. S of St Louis.N of Memphis • UNPLUG, UNWIND, RELAX. Adventure seekers only!

Top guest favourite
A spacious living area features large windows allowing natural light to fill the space. A comfortable grey sofa is paired with a unique coffee table, while stylish dining chairs surround a white table. The kitchen area includes modern appliances and cabinetry.
Flat in Cape Girardeau
4.95 out of 5 average rating, 310 reviews

Brand new 2 bedroom unit right in downtown Cape.

This special place is close to everything, making it easy to plan your visit. Walking distance to restaurants, the river and nightlife. Property includes wifi, full kitchen, laundry, deck and private parking for one. One king bed room and a twin bed room in addition to a roll out twin bed along with a 60 inch smart television. Dog bed and bowls included along with board games! Property is conveniently located across the street from "The Bar" the famous spot from the movie "Gone Girl" .

Guest favourite
The spacious living area features a comfortable couch and a coffee table, while a set of three barstools accompanies a sleek dining table. Natural light streams through multiple windows, highlighting the wood flooring and modern kitchen appliances in the background.
Tiny home in Jackson
4.95 out of 5 average rating, 59 reviews

The Cottage, Rusted Route Farms

You won’t forget your time in this romantic, memorable place. The Cottage at Rusted Route Farms is a 1 bedroom beautiful suite on an old 10 acre farm history galore. A picturesque pond is settled next to The Market our onsite Restaurant that will be serving food and drinks to be ready on your arrival or for a certain time that you choose. The over 125 year old barn has been renovated to keep the history alive and is located here on site. This retreat is located right outside Cape Girardeau.

Top guest favourite
A cozy living area is presented, featuring a stone fireplace with a mounted television above. Comfortable seating options include a leather armchair and a soft couch, arranged around a wooden coffee table. Natural light filters in through the window, enhancing the tranquil environment.
Cabin in Makanda
4.98 out of 5 average rating, 165 reviews

Sanctuary Cabin- Hot Tub & Woods

Hi, hello, welcome! We invite you to take it easy at this unique and tranquil getaway. The kitchen is stocked, the hot tub is ready to go, and the local area boasts many wineries, state parks for hiking, and beautiful scenery. This spacious cabin features a comfortable King bed, 55” TV above a gas fireplace, and recently had a top to bottom renovation! The spacious back deck features a large hot tub just steps from the back door, hooks for the provided terry cloth robes, and a Weber grill.

Guest favourite
A charming exterior view of a blue house is presented, featuring white trim and multiple windows. A covered porch area includes two red chairs and a black barbecue grill. Flower beds with plants are positioned along the front, set against a gravel area and surrounding greenery.
Home in Cobden
4.95 out of 5 average rating, 99 reviews

Wine trail cozy cabin! Hot Tub!

Beautiful home on the wine trail. Explore the Shawnee National Forest, Little Grand Canyon and Panoma Natural Bridge. See Giant City State Park. Enjoy near by wineries/orchards Close to Cedar Lake where you can swim or fish. Then relax in the quiet, peaceful setting. This home has been completely renovated with two bedrooms both with queen beds. A full bathroom and a spacious kitchen with everything you will need! Deck over looks 20 wooded acres with a wonderful hot tub. Pet friendly

Superhost
Tiny home in Cape Girardeau
4.81 out of 5 average rating, 31 reviews

Purple Tiny Home + Fire Pit & Nature

Stay in 'The Crystal Palace,' a vibrant purple tiny home featuring a signature round window and full exterior accessibility ramp. This open-concept studio sleeps 3 with a queen bed and convertible futon (small full size). Located in a colorful tiny home village, the unit includes a functional kitchenette, fast WiFi, and air conditioning. Enjoy the shared turquoise fire pit area and wooded surroundings just steps from Boulder Creek. Pet-friendly and equipped with free on-site parking.

Top guest favourite
A modern farmhouse is depicted at sunset, featuring a welcoming entrance with a covered porch. A stone pathway leads to the front door, bordered by a grassy lawn that extends to fields and trees in the background.
Barn in Cape Girardeau
4.95 out of 5 average rating, 260 reviews

Under the Stars - Farmhouse

Enjoy the tranquility of this modern farmhouse charmer! Custom built minutes from downtown Cape. Relax outside around the fire pit, roast marshmallows and watch the sunset. Finish the night with a long soak in the hot tub. Start the morning on the front porch rocking chairs and take in a sunrise. Open concept, fully equipped kitchen, 3 Bd. including King master/full bath, 2 Queens with full guest bath. Near Trail of Tears and walking distance to classic dive bar/burger joint

Guest favourite
Home in Cape Girardeau
4.92 out of 5 average rating, 183 reviews

College town Charm: Minutes from Downtown Cape

EXCELLENT LOCATION near downtown riverfront Cape! Enjoy live music, local dining/coffee, shopping, casino, and seasonal steamboat rides downtown. Less than 5 min. from Southeast Missouri State University & Southeast Hospital. Centrally located near wedding venues: Rusted Route, Deerfield, Watersedge, Sweet Pecan, and Country Club. 2 blocks from scenic Capaha Park. Home to Capaha baseball. This huge park includes play structures, basketball court, disc golf & fishing pond.

Top guest favourite
A wooden Japanese Ofuro soaking tub is illuminated by soft ambient lighting. Two individuals relax with their feet visible, surrounded by lush greenery and colorful garden lights. A glass of wine rests within reach, enhancing the serene ambiance.
Guest house in Carbondale
4.99 out of 5 average rating, 275 reviews

Carbondale Pool House - Sauna, Hot Tub, Dogs OK

Rated in “Top 1%” by Airbnb, the Pool House is a separate cottage surrounded by gardens and swimming pool, with retro "Danish Modern" furniture, a gourmet kitchen and plush beds. We have recently added a Finnish Sauna and Japanese Ofuro Soaking Tub. We accept well behaved dogs for a fee of $35 a night. We allow only guests and friends of the Pool House on the grounds, gardens or pool. Hosts are Jane, anthropologist and D. a retired photojournalist for the New York Times.

Top guest favourite
A cozy sitting area is surrounded by wooden walls, featuring a large window that offers views of the forest. A red chair stands next to a small side table, while a gray couch is positioned against the wall. Decorative art pieces adorn the space.
Tiny home in Cobden
4.95 out of 5 average rating, 130 reviews

Tiny House of Paul - Center For Lost Arts

Designed by architectural builder Paul Frank, Tiny House of Paul has a cozy & spacious feel. Twelve kinds of wood were used in the interior. It’s a unique space. A large west-facing window looks out onto the forest. Windows in the loft open to tree tops & stars. Private inside while being centrally located on the property of Center For Lost Arts near Cobden, Illinois. Wander the trails, or relax on the deck to begin or end your day. Enjoy your time in Southernmost Illinois.

Guest favourite
A charming duplex exterior is shown, featuring a red wooden facade with a light brown roof. Flower pots line the front, and multiple windows allow natural light. A gravel driveway leads to the entrance, with a satellite dish mounted on the roof.
Home in Makanda
4.84 out of 5 average rating, 128 reviews

Cedar Lake Retreat A

Enjoy a quiet, peaceful, pet-friendly retreat, less than a mile from Cedar Lake boat ramp/kayak launch and Poplar Camp Beach. This cute and comfy duplex is less than 6 miles from Giant City State Park, located in Shawnee National Forest, and just 4 miles from Southern Illinois University-Carbondale. Enjoy fishing, kayaking, and rock-climbing, or hit the Shawnee Wine Trails. If you’re a nature buff or you’re in town for SIU festivities, this is the place for you.

Popular amenities for Cape Girardeau pet-friendly home rentals

When is the best time to visit Cape Girardeau?

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