
Family-friendly holiday rentals in Cayce
Find and book unique family-friendly homes on Airbnb
Top-rated family-friendly rentals in Cayce
Guests agree: these family-friendly homes are highly rated for location, cleanliness and more.

Lucy’s Place
This 950 sq ft minimalist home is the perfect place to relax with family and friends. This West Columbia home is in a convenient spot for you to spread out and make yourself at home. The home is only 2 miles off of the interstate if you are just traveling through. You’ll be about 10 minutes from the University of South Carolina, Colonial Life Arena, the Statehouse, Riverbanks Zoo, Williams Brice Stadium, the Vista, The Columbia Riverwalk and many more local attractions if you are staying a while

Cozy 1BR Near USC & Riverbanks
Everything will be within your reach when you stay at this centrally located duplex located in the historic Earlewood neighborhood. Walking distance to beautiful Earlewood Park. A short drive to Segra Park (1.4 mi), downtown (2.1 mi), Columbia Canal & Riverfront Park (2.3 mi), Convention Ctr (2.4 mi), USC (2.5 mi), Publix Super Market (2.7 mi), Colonial Life Arena (2.7 mi), Riverbanks Zoo & Garden (3.1 mi), Five Points (3.3 mi), Saluda Riverwalk (3.3 mi), Ft Jackson (8.5 mi). Quiet neighborhood.

White Picket Fence - EV Charger!
*This pet-friendly home is ideally located. Local hospital just 3 blocks away Riverbanks Zoo & Gardens: A quick 4-mile drive Fort Jackson: 20 minutes away (11 miles) Congaree National Park: 22 miles (25 minutes) Interstate 26 (3 blocks) Exit 110 *Carport with a Tesla Level 2 Universal EV Charger. *Surrounded in a peaceful neighborhood trailer court for retired residents. *Your furry friend will love the fenced backyard, pet shelter, and pet door. No Pit Bulls or aggressive breads of any kind.

Private Studio Apartment
Crisp and cozy, modern studio apartment with private entrance, and access to park-like backyard, located right in the center of the Columbia, Irmo and Ballentine areas of SC. Quiet and tidy neighborhood, with free off-street parking for up to two vehicles. Just minutes from Lake Murray, Saluda Shoals Park and River, shopping and restaurants, approximatly 15-20 minutes from down town Columbia, the Vista, U of SC & CIU campuses, Williams-Brice Stadium, and about 20-25 minutes from Fort Jackson.

Heathwood 2Br/1Bath Cozy Home
Close to everything when you stay at this centrally located duplex. Close to the grocery store and restaurants. Five Points (1.5 miles), the Vista (2.5 miles), Township Auditorium (2 miles), USC (2 miles), and Ft Jackson (3 miles). This freshly renovated unit includes 2 bedrooms, 1 bath, fully equipped kitchen (including a k-cup coffee maker), washer and dryer. Both bedrooms have memory foam beds (1 King & 1 Queen). Keyless entry. Off street parking for 2 cars. COC Permit STRN-001336-10-2026

One SUITE Deal
The guest suite is located on the lower level of our tri-level home, with a private driveway, patio, and entrance. The queen bed and pull-out sofa sleep 4 guests comfortably. It is within 15 minutes of downtown, which is home to USC and the Colonial Life Arena. It is 10 minutes from Lake Murray, Riverbanks Zoo, shopping, movies, and great dining experiences. This suite is spacious and cozy. It's great for business travelers, traveling nurses, and small groups looking to enjoy local events.

Columbia’s Best Airbnb
Take it easy at this unique and tranquil getaway. Our Airbnbs are the nicest in each town. From our known luxurious mattresses to the best kept secret… 3D luxury digital Massage chairs relax you from any stressful situation. See why we are ambassador Airbnb host. Stay at this location and you are 5 to 10 minutes to the USC baseball, basketball and Football. Campus is same. Airport is 4 miles. Great kid activity at EdAdventure kid museum. I 26, I-77 and downtown Columbia are minutes away.

Lizzi & Scott’sTiny Guest House secluded USC-Vista
Welcome to our tiny guest cottage hidden in the heart of the city. It's within blocks of restaurants, coffee shops, an art movie house, and a lovely river walk. The Lace House/Governor’s Mansion, business district, MiLB & UofSC are a short walk or bike ride away. At the rear of our home, it’s private, secure & quiet. A partition & movable screen separate the bathroom area. There’s a smart tv, small fridge, microwave, coffeemaker & work-table.24 hr self check-in. STRO-000579-03-2024

The Avenues Bungalow
This space is great for a solo traveler or a couple! Great location, quiet neighborhood, close to everything. Mile and a half from USC campus (Carolina Baseball stadium, Colonial Life Arena and State house). Five miles from airport. Three miles from Williams-Brice Stadium. Three Miles from 5 points. Music venues, restaurants and riverwalk around the corner! Please note: This is a studio apartment in the back of a single family home. Private driveway, entrance and space.

High-styled Historic - (UofSC)
Built in 1959, this home has been completely remodeled with modern luxuries, and original hardwood floors throughout still tell the tales of decades of love and history. The decor gives a nod to a New York City loft style space, with a blend of both clean modern lines and warm rustic finishes. 1.2 mi - Steel Hands Brewing 1.8 mi - University of South Carolina 2.2 mi - Riverbanks Zoo & Garden 3.6 mi - Williams Brice Stadium 4.9 mi - Columbia Metropolitan Airport

In Columbia Metro! Easy drive to Fort Jackson/USC
Metro Columbia. 1.5 miles to USC. 9 miles to Fort Jackson! Entire single family home. Two bedrooms. One has a KING bed and the other has a QUEEN bed. One bath. Additional rollaway bed in an enclosed sunroom. Includes linens, sofa, loveseat, refrigerator, dishwasher, garbage disposal, wash machine, dryer, outdoor covered patio with rocking chairs and dining table overlooking the huge fenced, private backyard. Bright, comfortable, quiet. Plenty of parking.

The Toad Abode Studio
Relax and unwind in this cozy, centrally located studio. Perfect for travelers, the space features a comfortable double bed, work desk, cozy reading chair, and TV for your downtime. The kitchenette area includes a microwave & mini fridge with ample coffee & tea supplies, while the bright bathroom offers plenty of natural light. All the essentials you need for a comfortable stay. **Checkout on a Monday for more options at a discounted Sunday rate.
Popular amenities for Cayce family-friendly rentals
Family-friendly home rentals with a hot tub

Lake Murray: Panoramic Views, Kayaks & Hot Tub

Paradise Point

Unit A: Private Jacuzzi Suite w/Laundry + Fridge

Cute & cozy cabin in Lexington, SC

The Farmhouse @ Goat Daddy's

Lake Retreat

Lakefront w pool, dock and pool table, sleeps12

Luxury Treehouse in the heart of Columbia
Family- and pet-friendly home rentals

Cozy 3 BR Bungalow Located in Downtown Columbia

Gamecock Cottage @ Lake Murray-Waterfront w/ Dock

Perfect Family Place to Stay!

Downtown Blue BoHo w/ outdoor spaces, grill & FP

Freshly New House

Elmwood’s Modern Blue Bungalow

Brookhaven West

COLA CONDO 💫Btwn 5 points & Downtown Columbia!
Family-friendly home rentals with a pool

Modern Downtown Columbia Condo

Luxury Cozy Retreat with Private Pool

Say hello to Gem

Private Apartment in the woods

Lavish Home 4BR/3BA, King, Games, Grill, Pool!

Modern condo, closest to the University of SC

Peaceful Retreat Two

Mandalay RV
Quick stats about holiday rentals that are family-friendly in Cayce

Total holiday rentals
Explore 240 holiday rentals in Cayce

Nightly prices starting at
Cayce holiday rentals start at $52 SGD per night before taxes and fees

Verified guest reviews
Over 14,690 verified reviews to help you choose

Pet-friendly holiday rentals
Find 100 rentals that welcome pets

Holiday rentals with a pool
10 properties feature pools

Rentals with dedicated workspaces
150 properties have a dedicated workspace

Wifi availability
240 of Cayce holiday rentals include wifi access

Popular amenities for guests
Guests love Kitchen, Wifi and Pool across Cayce rentals

4.8 Average rating
Cayce stays are highly rated by guests – averaging 4.8 out of 5!
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