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Apartment holiday rentals in Santa Cruz

Find and book unique apartments on Airbnb

Top-rated apartment rentals in Santa Cruz

Guests agree: these apartments are highly rated for location, cleanliness and more.

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Top guest favourite
A modern living area is furnished with a gray sofa and a brown accent chair. A wooden coffee table sits on a textured rug in front of the sofa. Natural light floods in through large windows, illuminating the open layout that connects to an equipped kitchen.
Flat in Santa Cruz de la Sierra
4.98 out of 5 average rating, 49 reviews

Luxury and comfort in every detail

This apartment combines luxury, style, and comfort in every detail. Designed as a boutique hotel, it offers a unique experience with impeccable finishes, an equipped kitchen, a cozy living room, spacious bedrooms, and a beautiful balcony to relax. Located in the heart of Equipetrol and a short walk from restaurants, shops and attractions. Perfect for business trips or relaxation, this modern and elegant space is ideal for relaxing and enjoying an unforgettable stay. You'll love it! Parking is included!

Guest favourite
A modern living area is displayed, featuring a comfortable sofa and a green accent pouf. A dining table is situated nearby. Floor-to-ceiling windows offer a view of the greenery outside, allowing natural light to fill the space. The kitchen is equipped with sleek appliances.
Flat in Santa Cruz de la Sierra
4.91 out of 5 average rating, 152 reviews

Studio 518 - Luxury near Everything

Acceso automático, 2 Aires Acondicionados, Lavadora, Cocina, Sofa y TV perfecto para trabajar todo el día con una vista verde de un 8 piso desde el barrio más cotizado de la ciudad, Equipetrol. Si te aburres puedes usar la piscina sin costo, áreas sociales, asado BBQ. Si te aburres más estarás a 2 minutos de Supermercados, Farmacias a cuadras de la principal de Equipetrol con Restaurantes renombrados, a 5 min de la Plaza Central o a 5 min del shopping más grande de Bolivia, Ventura Mall.

Top guest favourite
An expansive rooftop pool is illuminated by soft lighting, reflecting the city skyline at night. Lounge chairs are neatly arranged along the pool's edge, and the sleek wooden deck complements the modern aesthetic of the space.
Flat in Santa Cruz de la Sierra
4.98 out of 5 average rating, 154 reviews

Luxurious and modern apartment. Equipetrol Sky Elite

This luxurious studio is located in the Equipetrol neighborhood, Sky Elite Building, one block from the Los Tajibos Hotel; it represents the perfect combination of exclusivity and first-class amenities in the city of Santa Cruz de la Sierra, surrounded by restaurants, shops, cafes, pharmacies and supermarkets. The building offers more than 3,000 square meters of social areas including a modern gym, extensive swimming pool, barbecue, coworking, private movie theater, sauna and whirlpool.

Guest favourite
A contemporary entryway featuring sleek, metallic walls and smooth marble flooring. A minimalist reception desk with soft ambient lighting displays the name 'NUU.' A large potted plant adds a touch of greenery, while well-placed lighting creates a bright atmosphere.
Flat in Santa Cruz de la Sierra
4.94 out of 5 average rating, 69 reviews

apartment with an excellent view

Apartment located in the Equipetrol area. Located on the 13th floor, you'll enjoy stunning views in a comfortable and elegant atmosphere. This apartment has two bedrooms and two bathrooms, ideal for families or groups. It's fully equipped to make you feel at home. Among the building's amenities, you will find a cinema, a swimming pool, a barbecue area, an equipped gym, a playground, and parking for visitors. Easy access to restaurants, shops, and attractions.

Top guest favourite
A well-appointed living space features a modern kitchen with wooden cabinetry and stainless steel appliances, including a refrigerator. A cozy seating area with a light gray sofa is arranged beside a spacious bed, while natural light filters through large windows.
Flat in Santa Cruz de la Sierra
5 out of 5 average rating, 55 reviews

Smart Studio in Equipetrol

Welcome to this great Smart Apartment in the best residential and business area of Equipetrol. You're half a block from Av. San Martin and a short walk from restaurants, shops, bars, and more. The apartment is fully furnished with everything you need for a comfortable stay, including a fully equipped kitchen, air conditioning, Wi-Fi, and a large flat-screen TV. It has a swimming pool, barbecue, co-work rooms and washing machines on the terrace and common areas

Top guest favourite
A comfortable sleeping area features a spacious bed adorned with soft pillows and a decorative throw. Warm bedside lamps illuminate the space, while large windows offer views of the surrounding cityscape and allow natural light to brighten the room.
Flat in Santa Cruz de la Sierra
4.98 out of 5 average rating, 132 reviews

13° SmartLife - Luxury Equipetrol

Welcome to your sanctuary of sophistication and elegance at the top. This exceptionally cozy and stylish studio on the 13th floor invites you to experience luxury and comfort at their finest. Ready to experience the perfect combination of sophistication, comfort, and technology? Don't miss out on this unique opportunity. Book your stay at "13° SmartLife" and be seduced by the charm of this incomparable space! Your urban retreat awaits.

Guest favourite
Flat in Santa Cruz de la Sierra
4.95 out of 5 average rating, 20 reviews

Luxury 1-bedroom apartment, equipped and close to everything.

Discover a luxury retreat in a quiet residential area. This 1-bedroom apartment offers a contemporary design and spaciousness that is noticeable in every detail: bright spaces, fully equipped kitchen. A place designed for your rest and comfort, with a queen bed, large closets, washing machine, TV in the living room and bedroom. Prime location near malls, restaurants, pharmacies and supermarkets. Enjoy total comfort and privacy.

Superhost
Flat in Santa Cruz de la Sierra
4.88 out of 5 average rating, 17 reviews

POX: Green Tower 16th floor | Luxury and elegance - 2H

Live the POX experience! We present our largest apartment in the iconic Green Tower, the most exclusive and luxurious building in Santa Cruz. A fully equipped apartment for you to live a unique experience with your family or friends. Be dazzled by the best view of the city, 24/7 service and close to banks, restaurants, shopping malls, everything you need meters away. We'll make sure you have a great stay, welcome to POX!

Top guest favourite
Flat in Santa Cruz de la Sierra
5 out of 5 average rating, 6 reviews

Luxury apartment across from the Hotel Yotaú

Disfruta una estadía única en el corazón de Equipetrol, la mejor zona de la ciudad. Ubicado en el piso 13, este moderno departamento ofrece una vista maravillosa y balcón privado para relajarte. Totalmente equipado para estadías cortas o largas, pensado para tu máxima comodidad. Además, disfruta de exclusivas áreas sociales de lujo que harán tu experiencia aún más especial.

Guest favourite
The lobby displays a modern aesthetic with concrete walls and a large piece of colorful artwork. A welcoming reception desk is prominent, accompanied by pendant lighting. A cozy seating area features a gray sofa and a round table, complemented by potted greenery and a light flooring.
Flat in Santa Cruz de la Sierra
4.81 out of 5 average rating, 186 reviews

Quartier Luxury 3

Luxurious apartment with an unbeatable location in Equipetrol. The space is fully furnished and you will be surrounded by a wide variety of restaurants, shops, close to major shopping malls, among others. The building has social areas on the top floor. Whether you're here for business or pleasure, our location will allow you to make the most of your time in the city.

Top guest favourite
Flat in Santa Cruz de la Sierra
5 out of 5 average rating, 31 reviews

Green Tower* 27th Floor Stunning views & Luxury

Truly the highest floor in the building, this modern luxury retreat soars above the city with breathtaking panoramic views. Sleek finishes, stylish decor, and plush comforts create a refined, high-end ambiance. Whether you’re sipping wine at sunset or waking up in the clouds, this stunning high-rise sanctuary delivers an unforgettable, elevated stay.

Guest favourite
A modern bedroom is featured with a spacious bed adorned in neutral tones. Two framed artworks are displayed above the headboard. Natural light enters through large glass doors that open to a private balcony, showcasing views of the surrounding city.
Flat in Santa Cruz de la Sierra
4.96 out of 5 average rating, 116 reviews

Apartment in Equipetrol with Rooftop Pool

✨ Elegant apartment in the vibrant Equipetrol area, ideal for business or leisure. Enjoy a modern design, high-speed Wi-Fi (293 Mbps), Smart TV, and air conditioning. Relax in the rooftop pool with panoramic city views. Perfect for short or long stays, combining comfort and security for an unforgettable experience.

Popular amenities for Santa Cruz apartment rentals

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