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Family-friendly holiday rentals in Santa Cruz

Find and book unique family-friendly homes on Airbnb

Top-rated family-friendly rentals in Santa Cruz

Guests agree: these family-friendly homes are highly rated for location, cleanliness and more.

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Top guest favourite
A modern living area is furnished with a gray sofa and a brown accent chair. A wooden coffee table sits on a textured rug in front of the sofa. Natural light floods in through large windows, illuminating the open layout that connects to an equipped kitchen.
Flat in Santa Cruz de la Sierra
4.98 out of 5 average rating, 55 reviews

Luxury and comfort in every detail

This apartment combines luxury, style, and comfort in every detail. Designed as a boutique hotel, it offers a unique experience with impeccable finishes, an equipped kitchen, a cozy living room, spacious bedrooms, and a beautiful balcony to relax. Located in the heart of Equipetrol and a short walk from restaurants, shops and attractions. Perfect for business trips or relaxation, this modern and elegant space is ideal for relaxing and enjoying an unforgettable stay. You'll love it! Parking is included!

Guest favourite
Flat in Santa Cruz de la Sierra
5.0 out of 5 average rating, 6 reviews

Skyline Luxury β€’ Rooftop, Piscina, Billar & Lounge

Designed for discerning guests seeking an experience superior to a 5-star hotel. Located in Equipetrol, the most exclusive and secure area of Santa Cruz, this elegant apartment on the second-to-last floor offers a double balcony with unique views! Premium amenities such as a sky pool, lounge, pool table, barbecue grills, fully equipped gym, and more! Surrounded by the best restaurants, bars, cafes, theaters, shops and business centers. Ideal for executive trips, luxury getaways or unforgettable stays.

Guest favourite
A contemporary entryway featuring sleek, metallic walls and smooth marble flooring. A minimalist reception desk with soft ambient lighting displays the name 'NUU.' A large potted plant adds a touch of greenery, while well-placed lighting creates a bright atmosphere.
Flat in Santa Cruz de la Sierra
4.92 out of 5 average rating, 76 reviews

apartment with an excellent view

Apartment located in the Equipetrol area. Located on the 13th floor, you'll enjoy stunning views in a comfortable and elegant atmosphere. This apartment has two bedrooms and two bathrooms, ideal for families or groups. It's fully equipped to make you feel at home. Among the building's amenities, you will find a cinema, a swimming pool, a barbecue area, an equipped gym, a playground, and parking for visitors. Easy access to restaurants, shops, and attractions.

Guest favourite
The cottage features a charming design with a sloped roof and wooden beams, surrounded by lush greenery and vibrant flower beds. A spacious porch offers outdoor seating. Large windows provide ample natural light, enhancing the inviting presence of the home within its tranquil garden setting.
Cabin in Samaipata
5.0 out of 5 average rating, 128 reviews

Kikita cabin, Samaipata

Magical place to recharge positive energy and vibes, surrounded by nature, with a temperate climate, considered The Switzerland of Bolivia , ideal for enjoying with family or friends, Samaipata means "Rest on the heights", very close to tourist places: El Fort de Samaipata (approx. 10 km) , Cuevas Water Falls (approx. 20 km) , Main square (500 meters approx.) , Boutique wines 1750 Uvairenda (3 km approx.), Zoo shelter (5 km approx) , trekking, mountain biking.

Top guest favourite
Flat in Santa Cruz de la Sierra
4.97 out of 5 average rating, 79 reviews

Premium 3-Bedroom Apartment | Pool | Macororo.

Enjoy a comfortable and elegant stay in this spacious 3-bedroom apartment at Macororo 13/14, on Av. Los Cusis. Great for families, groups and business trips. β€’ Heated pool and social areas β€’ Free private parking β€’ Fast Wi-Fi β€’ Equipped kitchen β€’ Washer & Dryer β€’ Smart TV Within walking distance, you'll find a 24-hour supermarket, Starbucks, restaurants, a mall, and a gym in front of the building. A comfortable, safe space designed for an excellent stay.

Top guest favourite
A comfortable sleeping area features a spacious bed adorned with soft pillows and a decorative throw. Warm bedside lamps illuminate the space, while large windows offer views of the surrounding cityscape and allow natural light to brighten the room.
Flat in Santa Cruz de la Sierra
4.98 out of 5 average rating, 135 reviews

13Β° SmartLife - Luxury Equipetrol

Welcome to your sanctuary of sophistication and elegance at the top. This exceptionally cozy and stylish studio on the 13th floor invites you to experience luxury and comfort at their finest. Ready to experience the perfect combination of sophistication, comfort, and technology? Don't miss out on this unique opportunity. Book your stay at "13Β° SmartLife" and be seduced by the charm of this incomparable space! Your urban retreat awaits.

Guest favourite
Flat in Santa Cruz de la Sierra
4.92 out of 5 average rating, 26 reviews

POX: Green Tower 16th floor | Luxury and elegance - 2H

Live the POX experience! We present our largest apartment in the iconic Green Tower, the most exclusive and luxurious building in Santa Cruz. A fully equipped apartment for you to live a unique experience with your family or friends. Be dazzled by the best view of the city, 24/7 service and close to banks, restaurants, shopping malls, everything you need meters away. We'll make sure you have a great stay, welcome to POX!

Top guest favourite
A spacious bed is positioned against a large window, offering a view of the cityscape. Soft pillows and a neatly arranged blanket enhance the comfort of the sleeping area. A small rug lies on the floor, complementing the modern decor.
Flat in Santa Cruz de la Sierra
4.89 out of 5 average rating, 149 reviews

Comfortable/modern studio apartment beautiful view 300Mbps

Welcome to the most active area of Santa Cruz! The price already includes all fees, you won't pay anything extra in the app. The apartment is a fully equipped, modern and comfortable studio. It has a double bed and a sofa bed in addition to a private bathroom, washer/dryer, kitchen and all the necessary appliances. Wi-Fi Internet, cable TV and NETFLIX. Close to supermarkets, the best restaurants in town and malls.

Superhost
Flat in Santa Cruz de la Sierra
4.84 out of 5 average rating, 107 reviews

new and modern apartment

Welcome to your new home in Equipetrol, the best area of Santa Cruz! This new and modern apartment offers you a cozy and comfortable space, ideal for you to enjoy your stay, whether for work or rest. Located in the heart of Equipetrol, you'll be surrounded by everything you need: supermarkets, banks, shops, pharmacies, cafes, restaurants, church and the Ventura Mall. We invite you to enjoy an unforgettable stay.

Guest favourite
Cottage in Samaipata
4.96 out of 5 average rating, 25 reviews

EcoHouse Β· Pool Β· Nature Β· Tranquility Β· Samaipata

A Living Earth Sanctuary on Samaipata Mountain Handcrafted with natural materials and a Bolivian soul. Welcome to CASA CACTUS β€” fully equipped and personalized for a stay surrounded by natural luxuries. 🏊 Pool Β· πŸ›œ Starlink Β· 🌿 Nature Β· Weekly and monthly DEALS *see below or contact us*. A place to really rest. To write. For slow cooking. To work online and offline. To look at the mountains without rushing.

Guest favourite
A modern bedroom features a spacious bed with light-colored bedding and decorative pillows. Wooden paneling creates a warm aesthetic, complemented by wall-mounted plants. Natural light enters through floor-to-ceiling windows, and a small bedside lamp offers a soft glow.
Apartment in Santa Cruz de la Sierra
4.94 out of 5 average rating, 139 reviews

Modern Studio in the center of Equipetrol

We offer you a comfortable stady with everything you may need, in this modern and new place with our top quality service. This place is fully furnished and has a beautiful view. Is located in the best area from Santa Cruz, and also near of fancy restaurants, malls and business area. You can have access to building's social areas like: co-work zone, pool, steakhouse and laundry. (pics)

Guest favourite
Loft in Santa Cruz de la Sierra
4.8 out of 5 average rating, 265 reviews

Equipetrol Exclusive Area Cozy Studio + Netflix

Enjoy your stay in a charming and functional fully equipped studio designed for your comfort. Located in Equipetrol, one of the most vibrant and safest areas of Santa Cruz. Relax in your free time in the pool and enjoy peace of mind with 24/7 security. Whether for work or rest, here you'll find the perfect balance between comfort, location, and style. We look forward to seeing you!

Popular amenities for Santa Cruz family-friendly rentals