
Holiday rentals in Santee River
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Top-rated holiday rentals in Santee River
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2 King bed 2 Bath*Walkable* Downtown Summerville
Hidden away amidst lush azaleas and towering pines, you will find yourself at the heart of small-town Southern Living. This two-story Guest House provides you with the perfect combination of secluded garden landscapes and downtown accessibility. Modern amenities and a whimsical interior design will make your stay in our charming cottage a time to remember. You'll be within a short walk of local shops and restaurants and an easy drive to downtown Charleston and surrounding beaches and attractions

★Delightful guest house near historic plantations★
Nestled in the Historic Plantation District between Summerville & Charleston, our timberframe "bunkhouse" offers privacy, comfort & convenience. This 850+ sq ft retreat includes full kitchen & bath, 2 dbl beds, twin bed & plenty of living space. There's a private entrance, so come & go as you please (we're right next door if you need us). Minutes from Middleton Place, Drayton Hall & Magnolia Gardens, an easy drive to dntn Charleston, historic S'ville, beaches & golf courses. *Now with WiFi*

Bridgerton inspired fantasy 2 min from park circle
Live out your Bridgerton fantasy in this stunning historic space. The apartment features antique furnishings/art, a private entrance and patio with lounge and a hot tub (The hot tub is available Apr through Nov). Off street parking. A sumptuous bathroom with an oversized soaking tub and a kitchenette. There is also a 55 inch frame tv in the bedroom including WiFi. Available for photo shoots upon request rates may differ please contact host prior. Bridal pics by Olivia Allain Permit#2026-0414

Black River Refuge on the Water
The first guest comment I hear is "Wow - pictures don't do this place justice - the house is incredible and the views are spectacular! The next comment is "I thought we were way out in the country but it's only 20 minutes to the waterfront town of Georgetown, with shops, dining, museums and more. Looking to get away? This place is truly a retreat- a 3 bedroom house on the beautiful Black River in Georgetown. Four kayaks provided, swim or fish off the dock just a few steps from the house.

Lo & Billy’s Place a Historic 1940s Newlywed Cabin
This romantic cabin located on our small farm just outside of town in the country offers a history all its own. Lo was Billy’s nickname for Lorene Ella. Lo & Billy got married in the 1950s and lived here. Renovated after meeting Lo and hearing her stories. We pay homage to the rich history of Georgetown and the Southerners that have called Lo & Billy’s Place home. Heavy on coziness & design. Full kitchen; good coffee; & comfy queen bed w/high end linens. The perfect escape.

"The Nest" At Maple Hollow
Welcome to our space-age glamping oasis, where you can immerse yourself in nature without sacrificing comfort. Our 400 SF ecological home, designed with advanced technology and sustainable features, offers a unique living experience. Nestled in a tranquil, rural setting, you'll enjoy stunning views of a duck and goose pond, providing a serene escape from the bustling city life. Despite its peaceful surroundings, our intelligent home ensures you stay connected to the world.

A Great Lake house. Near Manning, SC and I-95.
Secluded and serene, our private lakefront property in South Carolina's Lake Marion region offers a community feel with minimal traffic and noise. The fenced-in property has 2 cozy bedrooms, a large open floor plan, and a screen porch with a beautiful lake view. Enjoy the private dock, kayaks, and floats, and relax with a bonfire and grill. Conveniently located just 20 minutes from Manning and I-95, our retreat is perfect for travelers looking to unwind and recharge.

Resort @ Kit Hall Pool & Gardens, near Charleston
Centrally located between Myrtle Beach, Mount Pleasant and Charleston SC ( closest beach 36 miles by car. A sanctuary with an amazing freshwater (not chlorine or salt but Ionized)swimming pool, between two national parks, The Francis Marion National Forest & Cape Romain Wildlife Refuge. Near waterways, hiking, cycling trails, fishing, low country dining, historical plantations and more. 2 bedrooms & a screened sleeping porch. 4 beds + library, kitchenette & 2 ba

River Dome Retreat
Escape to a unique geodesic dome nestled along the serene riverbanks, offering a one-of-a-kind retreat for nature lovers. This architectural gem features panoramic views allowing guests to unwind. The interior boasts a cozy living space with modern amenities. Step outside to the spacious deck and immerse yourself in the sights and sounds of nature. Enjoy your own private boat ramp and dock! This geodesic dome on the river promises a memorable stay.

The Goose Cottage at Wild Goose Flower Farm
Located next to the family farmhouse at Wild Goose Flower Farm, The Goose Cottage was designed to immerse guests in our calm and peaceful country life. We are located 15 minutes from the hearts of Cane Bay, Nexton and Exit 194 on I-26, and 45 minutes from Downtown Charleston. Two can sleep in the queen size bed and one can sleep on the couch. Please reach out with further questions or if you would like to inquire about an extended stay.

The Wrenn’s Nest - Quaint National Forest Getaway
The Wrenn's Nest is a cozy two-bedroom cottage in the Francis Marion National Forest. Perfect for outdoor activities like hiking, fishing, and birdwatching, it offers a peaceful retreat with modern comforts. Located in Cordesville, SC, just 15 minutes from Moncks Corner, it’s surrounded by nature with few neighbors. Enjoy amenities like a laundry nook, fire pit, and a spacious lot. Guests are our priority, and we’re always here to help!

Cutest Cottage on the Lake
Keep it simple at this peaceful and centrally-located cottage on Lake Moultrie in Moncks Corner SC, right outside of Charleston. Bring your boat and launch off of our dock, easy in and out access to the big lake. Our home sleeps 6 on our King bed, 2 twins and a pull out couch. Recently renovated, all the modern luxuries are provided. There is a fire pit to enjoy while you grill on our charcoal grill. Eat outside, enjoy the view!
Popular amenities for Santee River holiday rentals
Other great holiday rentals in Santee River

Cabin on French Quarter Creek

Reelaxation-At Lake Marion

Lakefront Cabin Compound w Private Dock!

The Boat Shed

The Anita Suite.

Lakefront Fishing + Grilling | Home Sweet Home!

The Cabin at Cool Blow Farms

TIME TO RELAX with this direct waterfront home
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- Sullivan's Island Beach
- Isle of Palms Beach
- Garden City Beach
- Huntington Beach State Park
- Charleston City Market
- Bulls Island
- James Island County Park
- Waterfront Park
- College of Charleston
- North Charleston Coliseum & Performing Arts Center
- Shem Creek Park
- Rainbow Row
- Riverfront Park
- Caledonia Golf & Fish Club
- Hampton Park
- The Charleston Museum
- Magnolia Plantation & Gardens
- Middleton Place
- Angel Oak Tree
- White Point Garden
- Murrells Inlet Marsh Walk
- The Citadel
- Boone Hall Plantation
- Gibbes Museum of Art





