Holiday rentals in Santee River

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Top-rated holiday rentals in Santee River

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Top guest favourite
An airy loft space features a suspended wooden swing, inviting relaxation under the high, timbered ceilings. Natural light streams through large windows, illuminating cozy furnishings including a bed and a dining area with a wooden table. Unique decor elements enhance the overall character.
Guest house in Summerville
4.98 out of 5 average rating, 771 reviews

★Delightful guest house near historic plantations★

Nestled in the Historic Plantation District between Summerville & Charleston, our timberframe "bunkhouse" offers privacy, comfort & convenience. This 850+ sq ft retreat includes full kitchen & bath, 2 dbl beds, twin bed & plenty of living space. There's a private entrance, so come & go as you please (we're right next door if you need us). Minutes from Middleton Place, Drayton Hall & Magnolia Gardens, an easy drive to dntn Charleston, historic S'ville, beaches & golf courses. *Now with WiFi*

Top guest favourite
The exterior of a two-story house is nestled among tall trees, showcasing a deck with steps leading to the ground. Screened-in porches on both levels provide ample outdoor space and views of the surrounding greenery.
Home in Georgetown
4.98 out of 5 average rating, 186 reviews

Black River Refuge on the Water

The first guest comment I hear is "Wow - pictures don't do this place justice - the house is incredible and the views are spectacular! The next comment is "I thought we were way out in the country but it's only 20 minutes to the waterfront town of Georgetown, with shops, dining, museums and more. Looking to get away? This place is truly a retreat- a 3 bedroom house on the beautiful Black River in Georgetown. Four kayaks provided, swim or fish off the dock just a few steps from the house.

Top guest favourite
The image captures a serene landscape where sunlight filters through trees, casting long shadows on the grassy ground. Spanish moss drapes from branches, creating a tranquil and inviting scene alongside the waterfront.
Home in North Charleston
4.99 out of 5 average rating, 142 reviews

Waterfront Nature’s Retreat Cottage 2Bd/2B

Take it easy at this unique & tranquil waterfront getaway where you will be able to enjoy the stunning views of the Ashley river and beautiful sunsets over Magnolia Gardens. The 2 BR Cottage is located on 1.5 acres on private property Whether you are here for work or play, this property is centrally located: Min from airport, outlets, breweries, restaurants, I-26, 526, Boeing, 20 min from DT Charleston 30 min from the beach. NO PARTIES NO SMOCKING NO PET NO SWIMMING NO DOCK ACCESS 5 PERS

Top guest favourite
A single-story house with a combination of brick and siding exterior is situated in a spacious yard. Surrounding trees provide shade, and the gravel driveway leads to the entrance. The structure features multiple windows, allowing natural light to fill the interior.
Home in Moncks Corner
4.98 out of 5 average rating, 175 reviews

Your home away from home in Pinopolis

Nestled at the end of a quiet cul-de-sac, this house is close to Lake Moultrie & the Cooper River. It’s also very close to popular wedding venues: Somerset Point, Pineland Village, & Old Santee Canal Park. Moncks Corner Recreational Complex, where many tournaments are hosted, is also about 3 miles away. Pinopolis is less than 20 miles from Summerville & the Volvo area, 40 miles from coastal beaches, and just 45 minutes away from Downtown Charleston. It’s a great location for work or play!

Top guest favourite
A cozy seating area features a soft armchair and a tufted ottoman, positioned near a stone fireplace. Built-in shelves display decorative items and books. Expansive glass doors provide natural light and a view of the outdoor space, enhancing the inviting ambiance.
Guest house in Summerville
4.99 out of 5 average rating, 70 reviews

Cottage 1 king bed, 1 set bunk beds, heated pool

Escape to a cozy, beautifully furnished cottage nestled in historic Summerville, just a stroll away from the heart of the town. Whether you're a couple seeking a romantic getaway or a small family looking for a peaceful home base, this cottage offers the perfect blend of comfort, character, and convenience. The patio is ideal for relaxing mornings or evening meals under the stars. With easy access and free parking, it's perfect for day trips to the beach, Charleston, or a walk into town.

Top guest favourite
Farm stay in Eutawville
4.94 out of 5 average rating, 17 reviews

Luxury Farm Stay | Hot Tub, Pool & Animals

Welcome to The Days End Farm! Where modern comfort meets country charm 🌾 This home is for quiet stays only — no parties or events are allowed. A thoughtfully designed 700 sq ft farm cabin retreat tucked away on 11 acres of peaceful pastures. Located less than 45 min from downtown Summerville, 40 min from I-20, 1 hr from Downtown Charleston, and 25 min from I-95. We are a livestock property and for the safety of our animals we only allow 1 pet per reservation with a strict leash policy.

Top guest favourite
The entrance of the cabin features a modern black exterior with a circular welcome mat and a stylish door showcasing large glass panes. Potted white flowers add a touch of nature, while an outdoor chair invites relaxation amidst the greenery of surrounding trees.
Farm stay in Georgetown
4.99 out of 5 average rating, 77 reviews

Lo & Billy’s Place a Historic 1940s Newlywed Cabin

This romantic cabin located on our small farm just outside of town in the country offers a history all its own. Lo was Billy’s nickname for Lorene Ella. Lo & Billy got married in the 1950s and lived here. Renovated after meeting Lo and hearing her stories. We pay homage to the rich history of Georgetown and the Southerners that have called Lo & Billy’s Place home. Heavy on coziness & design. Full kitchen; good coffee; & comfy queen bed w/high end linens. The perfect escape.

Guest favourite
Tiny home in St. Stephen
4.95 out of 5 average rating, 19 reviews

"The Nest" At Maple Hollow

Welcome to our space-age glamping oasis, where you can immerse yourself in nature without sacrificing comfort. Our 400 SF ecological home, designed with advanced technology and sustainable features, offers a unique living experience. Nestled in a tranquil, rural setting, you'll enjoy stunning views of a duck and goose pond, providing a serene escape from the bustling city life. Despite its peaceful surroundings, our intelligent home ensures you stay connected to the world.

Superhost
Aerial view of a lakefront property shows a private dock extending into calm waters, surrounded by lush greenery. The house, nestled among trees, features a spacious yard with a fenced area and a screened porch visible. The tranquil setting emphasizes the natural beauty of the location.
Cottage in Manning
4.75 out of 5 average rating, 173 reviews

A Great Lake house. Near Manning, SC and I-95.

Secluded and serene, our private lakefront property in South Carolina's Lake Marion region offers a community feel with minimal traffic and noise. The fenced-in property has 2 cozy bedrooms, a large open floor plan, and a screen porch with a beautiful lake view. Enjoy the private dock, kayaks, and floats, and relax with a bonfire and grill. Conveniently located just 20 minutes from Manning and I-95, our retreat is perfect for travelers looking to unwind and recharge.

Guest favourite
Large triangular windows provide panoramic views of the river and surrounding greenery. A small wooden table and two black chairs sit in the corner, complementing the spacious interior. Natural light fills the room, enhancing the sense of openness and connection to nature.
Dome in Moncks Corner
4.97 out of 5 average rating, 68 reviews

River Dome Retreat

Escape to a unique geodesic dome nestled along the serene riverbanks, offering a one-of-a-kind retreat for nature lovers. This architectural gem features panoramic views allowing guests to unwind. The interior boasts a cozy living space with modern amenities. Step outside to the spacious deck and immerse yourself in the sights and sounds of nature. Enjoy your own private boat ramp and dock! This geodesic dome on the river promises a memorable stay.

Top guest favourite
A field of blooming yellow flowers is displayed in the foreground, with delicate petals and green stems. In the background, a white farmhouse is visible, providing a serene country setting. The scene captures the tranquility of the flower field adjacent to the cottage.
Tiny home in Moncks Corner
4.95 out of 5 average rating, 166 reviews

The Goose Cottage at Wild Goose Flower Farm

Located next to the family farmhouse at Wild Goose Flower Farm, The Goose Cottage was designed to immerse guests in our calm and peaceful country life. We are located 15 minutes from the hearts of Cane Bay, Nexton and Exit 194 on I-26, and 45 minutes from Downtown Charleston. Two can sleep in the queen size bed and one can sleep on the couch. Please reach out with further questions or if you would like to inquire about an extended stay.

Top guest favourite
Home in Cordesville
5.0 out of 5 average rating, 80 reviews

The Wrenn’s Nest - Quaint National Forest Getaway

The Wrenn's Nest is a cozy two-bedroom cottage in the Francis Marion National Forest. Perfect for outdoor activities like hiking, fishing, and birdwatching, it offers a peaceful retreat with modern comforts. Located in Cordesville, SC, just 15 minutes from Moncks Corner, it’s surrounded by nature with few neighbors. Enjoy amenities like a laundry nook, fire pit, and a spacious lot. Guests are our priority, and we’re always here to help!

Popular amenities for Santee River holiday rentals