Holiday rentals in Santee River

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Top-rated holiday rentals in Santee River

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Top guest favourite
A spacious living area features a light gray sectional sofa and a comfortable armchair. A wooden coffee table sits in the center, adorned with decorative elements. A television is mounted above a gas fireplace, and soft natural light fills the space through nearby windows.
Apartment in Moncks Corner
4.98 out of 5 average rating, 55 reviews

Updated 2BR condo with balcony

Enjoy a getaway to this relaxing and peaceful second-floor condo unit in Moncks Corner. You will feel right at home with a fully equipped kitchen, tasteful decor, and in-unit washer & dryer. Conveniently located in town and walking distance to many stores, restaurants and the new Hidden Cove Marina. Also boat trailer parking is available if needed. After a day of exploring, unwind on the private balcony or kick back and enjoy streaming on one of 3 smart TVs. Community pool is open seasonally.

Top guest favourite
A charming country estate is highlighted with a wrap-around porch surrounded by lush greenery. The architectural details feature brick and wood elements, with a tall chimney visible. Sunlight gently illuminates the exterior, showcasing the inviting atmosphere of the property.
Home in Kingstree
4.94 out of 5 average rating, 134 reviews

magical 1840s farm house getaway

Centuries old country estate with magical ambiance, art and antiques, beautiful views and wrap around porches. Relax in the hot tub in your own private oasis or gather with friends and family around the fire pit. Multiple bird feeders and grand live oaks, magnolias, fruit trees and a kitchen garden. Chefs kitchen will be stocked with fresh eggs, herbs and seasonal veggies. Sit and sip on the porch while enjoying the views of farmer's field and listing to the moos of the cows. Groups welcome!

Top guest favourite
An airy loft space features a suspended wooden swing, inviting relaxation under the high, timbered ceilings. Natural light streams through large windows, illuminating cozy furnishings including a bed and a dining area with a wooden table. Unique decor elements enhance the overall character.
Guest house in Summerville
4.98 out of 5 average rating, 742 reviews

★Delightful guest house near historic plantations★

Nestled in the Historic Plantation District between Summerville & Charleston, our timberframe "bunkhouse" offers privacy, comfort & convenience. This 850+ sq ft retreat includes full kitchen & bath, 2 dbl beds, twin bed & plenty of living space. There's a private entrance, so come & go as you please (we're right next door if you need us). Minutes from Middleton Place, Drayton Hall & Magnolia Gardens, an easy drive to dntn Charleston, historic S'ville, beaches & golf courses. *Now with WiFi*

Top guest favourite
A welcoming living area features a cozy couch and an accent chair, complemented by a wooden coffee table and a media console with a television. Light enters through a large window adorned with beige curtains, enhancing the warm tones of the wooden ceiling.
Home in Moncks Corner
5 out of 5 average rating, 100 reviews

The Boho Barndo

Take it easy at this unique and tranquil getaway. The Boho Barndo is the perfect spot to get away. Well stocked to make your stay comfortable. We are just 20 min from Downtown Summerville, 30 min from the Charleston International Airport and 5 min from shopping and dinning. The barndo is located on a large 5 ac. tract. The entrance is gated and you will have your own designated parking area. The main house is located about 250 yrds away from the barndo and allows you to enjoy peace and quite

Top guest favourite
A charming log home is set on a grassy lot, surrounded by trees. The façade showcases large windows that invite natural light inside. A wooden deck extends from the entrance, providing a space for outdoor seating. A paved pathway leads to the front steps.
Cabin in Vance
4.9 out of 5 average rating, 228 reviews

Log home on Lake Marion inlet w/private dock.

Relax with family and friends at this peaceful lake home. Located on an inlet one minute off the largest lake in South Carolina, Lake Marion is known for it's big fish and abundant wildlife. With your own private dock, you can boat/fish all day and leave your boat in the water for your entire stay. If you enjoy golfing, three of the states best golf courses are within minutes. This log home is centrally located between Columbia and Charleston. Restaurants, shopping, and beaches all close by.

Guest favourite
A well-appointed sleeping area is featured, showcasing a spacious bed dressed in a light coverlet. A cozy armchair sits nearby, complemented by a decorative wall sign and a serene landscape painting. Natural light enters through a sheer white curtain by the window.
Tiny home in Moncks Corner
4.92 out of 5 average rating, 163 reviews

Tiny House studio stay in Moncks Corner

The tiny house is located in our backyard in a small town, Moncks Corner, South Carolina. As you enter the house, you will notice that it is small but it has everything you will need to enjoy your stay! A kitchen to cook in, a table to eat or work at, a nice place to shower and sleep - all in the same room. It is small yet very comfortable and welcoming! We operate off of well water. If you are not used to well water, the smell can sometimes be surprising. Please note: the water is safe.

Top guest favourite
A bright living area displays a comfortable arrangement of a yellow sofa and two gray chairs around a central table. A modern art piece adorns the wall, while natural light filters through a window with light-colored blinds, complementing the open layout that connects to the kitchen.
Home in North Charleston
4.93 out of 5 average rating, 173 reviews

Charming Park Circle Two Bedroom with Fenced Yard

Welcome to your cozy getaway in Park Circle! This charming two-bedroom, one-bath cottage features an inviting open floor plan that creates a warm and welcoming atmosphere. As you step inside, you’ll be greeted by a bright and airy living space that seamlessly connects to the dining area and fully equipped kitchen. This layout maximizes comfort and convenience. With easy access to downtown Charleston and nearby beaches, this cottage is the perfect base for your Lowcountry adventures.

Top guest favourite
The exterior of the villa is shown, featuring a light-colored stucco façade contrasted by large windows. Surrounding landscaped areas include planters with vibrant greenery and flowers. A gravel pathway leads to the entrance, framed by the natural beauty of trees in the background.
Home in Summerville
4.92 out of 5 average rating, 148 reviews

Guest House/Villa

Enjoy your stay at this immaculately designed new build Villa. Located on a family property surrounded by 2 acres of trees, in a quiet rural neighborhood. Lots of privacy, peace and quiet, yet only 5 minutes from restaurants and stores. 15 minutes from Downtown Summerville, 40 minutes from Charleston and various coastal attractions. The villa is separate from main house and has no shared space other than the driveway. NO smoking, No pets. Laundry service available for long stays.

Top guest favourite
A field of blooming yellow flowers is displayed in the foreground, with delicate petals and green stems. In the background, a white farmhouse is visible, providing a serene country setting. The scene captures the tranquility of the flower field adjacent to the cottage.
Tiny home in Moncks Corner
4.95 out of 5 average rating, 148 reviews

The Goose Cottage at Wild Goose Flower Farm

Located next to the family farmhouse at Wild Goose Flower Farm, The Goose Cottage was designed to immerse guests in our calm and peaceful country life. We are located 15 minutes from the hearts of Cane Bay, Nexton and Exit 194 on I-26, and 45 minutes from Downtown Charleston. Two can sleep in the queen size bed but the sofa also extends into a queen-sized sleeper. Please reach out with further questions or if you would like to inquire about an extended stay.

Guest favourite
A bright and airy screened porch features two modern lounge chairs, accented with decorative pillows. Natural light filters through large windows, showcasing greenery outside and a wooden deck floor that adds warmth to the serene space.
Cottage in North Charleston
4.98 out of 5 average rating, 238 reviews

Silverlight Cottage in Park Circle

A spacious retreat (780 sq ft.) in Park Circle: Elegant, gracious + charming. Brand new custom built guest house designed with a nod to classic Charleston architectural influence: open concept indoor - outdoor space to large shady screened porch where a perpetual breeze from the not-too-distant coastline blows gently all year round. Visitors will return from their travel deeply restored and revived - having experienced well-appointed accommodation.

Top guest favourite
Home in Cordesville
5 out of 5 average rating, 66 reviews

The Wrenn’s Nest - Quaint National Forest Getaway

The Wrenn's Nest is a cozy two-bedroom cottage in the Francis Marion National Forest. Perfect for outdoor activities like hiking, fishing, and birdwatching, it offers a peaceful retreat with modern comforts. Located in Cordesville, SC, just 15 minutes from Moncks Corner, it’s surrounded by nature with few neighbors. Enjoy amenities like a laundry nook, fire pit, and a spacious lot. Guests are our priority, and we’re always here to help!

Superhost
A single-story cottage is surrounded by trees, featuring a gray exterior and a spacious front porch with steps leading to the entrance. A circular pathway made of gravel encircles the grounds, with a storage shed visible to the right.
Home in Moncks Corner
5 out of 5 average rating, 27 reviews

Cutest Cottage on the Lake

Keep it simple at this peaceful and centrally-located cottage on Lake Moultrie in Moncks Corner SC, right outside of Charleston. Bring your boat and launch off of our dock, easy in and out access to the big lake. Our home sleeps 6 on our King bed, 2 twins and a pull out couch. Recently renovated, all the modern luxuries are provided. There is a fire pit to enjoy while you grill on our charcoal grill. Eat outside, enjoy the view!

Popular amenities for Santee River holiday rentals