
House holiday rentals in Santo Domingo
Find and book unique houses on Airbnb
Top-rated house rentals in Santo Domingo
Guests agree: these houses are highly rated for location, cleanliness and more.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for house rentals in Santo Domingo
House rentals with a pool

A Good Walk-Pedasi

Tropical Townhouse Living

Beautiful Home Directly on Playa Venao Sleeps 8-10

Modern Beach Home with pool and hot tub

Luxury Villa

Casita with plunge pool near parque in Pedasi!

Nearly Oceanfront: Blue 3 Bedroom Spacious Villa

Casa Del Amor in Pedasi, Panama Oceanfront paradise
Weekly house rentals

Casa Amarilla-Cozy 2Bed/1Bath/Pocri, Las Tablas

Our Happy Place

Minimalist House In Chitre

Peaceful Pedasi

Entire house in Herrera

Chitré: Weliss's House

House in Las Tablas, with a swimming pool and beach access

Your Home Away From Home: Simple and Centrally Located
Private house rentals

Ocean View, Ocean View El Ciruelo

Great for Festivities

La Hacienda Ojo de Agua * Family & Friends Getaway

rainbow in the redelefant farm

La Casita 4BR Spacious Private Paradise w/pool

Casa Ola – Tropical Beachside Escape

Cozy country-style house.

Cozy house in El Ejido
Quick stats about house rentals in Santo Domingo
Total rentals
30 properties
Nightly prices starting at
$39 SGD before taxes and fees
Total number of reviews
240 reviews
Family-friendly rentals
10 properties are a good fit for families
Pet-friendly rentals
20 properties allow pets
Rentals with dedicated workspaces
10 properties have a dedicated workspace
Destinations to explore
- Panama City Holiday rentals
- Puerto Viejo de Talamanca Holiday rentals
- Uvita Holiday rentals
- Boquete Holiday rentals
- Quepos Holiday rentals
- Playa Blanca Holiday rentals
- Bahía Ballena Holiday rentals
- Limón Holiday rentals
- Ancón Holiday rentals
- Cahuita Holiday rentals
- David Holiday rentals
- Valle de Anton Holiday rentals