
House holiday rentals in Central Business District
Find and book unique houses on Airbnb
Top-rated house rentals in Central Business District
Guests agree: these houses are highly rated for location, cleanliness and more.

Nulu Liberty House
This beautifully updated home was named the #1 PET FRIENDLY Airbnb in Louisville by Trip101! Located in Louisville's hottest neighborhood, you'll be a short walk from a variety of restaurants, bars, local coffee shops, parks, bourbon distilleries and more! The kitchen and living room are inviting and fully stocked for you to relax with friends. All 3 bedrooms are spacious and comfortable and designed for you relax and make the most of your trip to beautiful Louisville. We can't wait to host you!

Bourbon Trail Spacious Backyard NEW HotTub Grill!
The Burnt Barrel, discover your vibrant Louisville getaway! Perfect for couples, business travelers, or event visitors, this cozy home offers high-speed Wi-Fi and a dedicated workspace, fully equipped kitchen, and a NEW hot tub and grill for you to enjoy! Guests rave about its comfort, walkable location, and modern amenities. Enjoy nearby bars and restaurants all just minutes from downtown, UofL Health, and the Convention Center. Experience true Louisville charm and convenience! Book a stay now!

Best for Derby and Bourbon Trail!
NOTE SPECIAL CANCELLATION POLICY FOR DERBY AND BOURBON AND BEYOND BOOKINGS! Original charm with a modern twist. Reno'd 1900s shotgun home perched on the Kentucky Bourbon Trail. Enjoy a comfortable stay near Louisville's best spots in the historic Highlands/Germantown neighborhood. Notice that we have THREE full baths. Swan Haus is luxuriously spacious for 2, perfect for 4, and very comfortable for 6 guests who plan to be out and about enjoying the city. Swan Haus is the place to stay anytime!

Walk to Everything • Quiet, Private, and Cozy
Tucked along a quiet, tree-lined street in Louisville’s Original Highlands neighborhood, you’ll find a cozy, private retreat filled with character and unique decor. Featuring a large master bedroom with king Sleep Number bed, a spacious living/dining room area, 2 full bathrooms, and a cozy full sized guest room. Walk to the best restaurants, boutiques, and coffee shops. Explore the nearby parks or unwind in your peaceful, historic hideaway. 1 mile from NULU 2 from downtown 5 from the Downs

Pool Table Getaway: Eclectic Vibes in Central Lou
An experience you can't get at a hotel! Your home is built around a full-size POOL TABLE — the place to reconvene & relax after a long day of excitement. We've decorated the house with plush king beds and furniture, a large & fully-stocked kitchen, eclectic art, 75" and 55" TVs, and room to breathe. Dog & kid friendly — your pup runs free in a fenced backyard. Dead-center in Louisville: NuLu, Churchill Downs, Waterfront Park, Bardstown Rd all close. Hands-off hosts, but always at your service!

The House with the Orange Door
Near Churchill Downs (7mins) UofL (5mins) downtown (10mins) Convention Center (10mins) Fairgrounds (4mins), and close to restaurants, bars and coffee shops. The home offers two bedrooms with queen beds and a pull-out couch in the living room. Enjoy coffee or a relaxing evening on the back deck. The kitchen is fully equipped and the open living space provides a great area for socializing. Locally made art and decor is on display, adding to the uniqueness of the space. No local bookings please!

Walking Bridge, Putt Putt House
NEW LISTING: Welcome to our walking bridge home on Pearl St. We have a hot tub, putt putt, and all the fun you can think of in one home. Steps away from restaurants, shopping, and bars, as well as the walking bridge to Louisville. This home is closer to the fun in Louisville than most neighborhoods in Louisville itself. Go out or stay in, you're guaranteed to have a great time in this newly renovated gem. We have high quality mattresses, and smart TV's in both bedrooms and the living room.

Hot Property! Music Fests- LTL, B&B, & KyDerby!
Shotgun Rye is ready to host your stay in Louisville! Located close to everything cool in Germantown and Highlands area! People visit for Bourbon Tours, Ky Derby, Conventions, Expo Ctr, UL graduations and sporting events, live music and so much more! Completely remodeled with all the modern conveniences & a comfortable, casual touch. But with so much to see and do in Louisville you’ll load up your itinerary with unforgettable experiences. Great location walk to bars, restaurants and shopping!

Butchertown & NuLu's Shantyboathouse
Welcome to the Shantyboathouse! Recognized as a truly unique property, it has twice been featured in the Courier-Journal and was honored with a historical plaque by the Louisville Landmarks Commission in 2019. According to a 1976 newspaper article, a local legend recounts that the house floated up the river during the 1937 flood, and was later set on a foundation—earning it the enduring nickname, "the shanty boat." This rich history adds to the property's distinctive character and charm.

Hot Tub | Fenced-in Yard | King Bed | Walk to Nulu
5-minute walk to the heart of NuLu and close to the Bourbon Trail Backyard retreat with colorful flowers, a hot tub, fire pit, and outdoor dining area Chef-ready kitchen featuring an Instant Pot, rice cooker, toaster, and just about every coffee maker imaginable Full cable TV plus streaming access to Netflix, Disney+, Hulu, and HBO Max Nintendo Switch with multiple games for all ages Board game collection for fun nights in 15 minutes to Churchill Downs, UofL, and the airport

The Baxter IV - Family Friendly
This stylish place to stay is perfect for your trips! Located at the heart of Louisville, in a centenary house. Completely remodeled, cozy and the Louisville nightlife is just outside the door. In the morning, you can relax on the porch enjoying a cup of coffee. During your stay spend time walking the neighborhood filled with boutiques, restaurants, bars, distilleries and art galleries. Start the bourbon trail or walk to the famous Cave Hills Cemetery. Enjoy weird Louisville!

DOWNTOWN LOUISVILLE ⭐ Expo Center⭐ 3 BR, 2 BT
- 3 min drive to U of Louisville - 5 min drive to KY Expo Center - 7 min drive to Louisville Zoo This gorgeous 3-bed, 2-bath house is less than 4 miles from downtown Louisville. With its fully-equipped kitchen, spacious rooms & completely renovated kitchen, the house is the perfect base for large groups wanting to explore the city. Enjoy the wide variety of shops, restaurants, & bars nearby. Kentucky Derby fans love the close proximity to Churchill Downs. No Locals Please
Popular amenities for house rentals in Central Business District
House rentals with a pool

Louisville KY Home w/Hot Tub & Pool

The Getaway!

8 Min to Bourbon Fest | 6 Kings + Hot Tub

Top 1%• Yard + Porch • 3BR • Peppermint Cottage

CIRCO LOCO - uNCommon Stay

Urban Lakeside 3BR Retreat Private Pool

ꕥEntire Triple CrownꕥSlps 18, HOT TUB, POOL, firpt

Rock & Roll Riverhouse | Pool | Mins to Louisville
Weekly house rentals

Top Floor Penthouse at the Historic Levy Building

Bright & cozy Louisville home w/ private backyard

The NULU Hideaway - downtown Louisville

Peaceful Modern Retreat • Prime Location!

Magical Fairytale Nulu - Historic 2BR Pet Friendly

HotTub-Firepit-King Bed-Walkable-Coffee Bar

Derby-ready home near Churchill Downs with parking

The Cottage @ Mellwood
Private house rentals

The Long Shot | Mini Golf, Hot Tub, Fire Pit, BBQ

Walk to River! Game system!

Lay Low B-Side | NULU | 2BR | Balcony

Mint Julep Suite & Bourbon Room | Sleeps 2

The Mashbill | Boutique Bourbon Retreat | Walkable

NULU LOFTS - Urban Bourbon Trail

Walk to Louisville/Hot Tub

Louisville Luxury: Expo Center, Hot Tub, Bourbon
Quick stats about house rentals in Central Business District

Nightly prices starting at
Central Business District holiday rentals start at $330 SGD per night before taxes and fees

Verified guest reviews
Over 270 verified reviews to help you choose

Popular amenities for guests
Guests love Kitchen, Wifi and Pool across Central Business District rentals

4.9 Average rating
Central Business District stays are highly rated by guests – averaging 4.9 out of 5!

Nearby attractions
Central Business District’s top spots include Fourth Street Live!, Louisville Slugger Museum & Factory and Louisville Slugger Field
Destinations to explore
- Flat rentals Downtown
- Rentals with a hot tub Downtown
- Pet-friendly rentals Downtown
- Rentals with breakfast Downtown
- Rentals with an EV charger Downtown
- Rentals with pools Downtown
- Rentals with outdoor seating Downtown
- Hotel rooms Downtown
- Loft rentals Downtown
- Rentals with an accessible-height toilet Downtown
- Rentals with a firepit Downtown
- Rentals with a patio Downtown
- Waterfront rentals Downtown
- Apartment rentals Downtown
- Fitness-friendly rentals Downtown
- Rentals with a washing machine and dryer Downtown
- Family-friendly rentals Downtown
- House rentals Louisville
- House rentals Jefferson County
- House rentals Kentucky
- House rentals United States
- Buffalo Trace Distillery
- Kentucky Exposition Center
- Kentucky Derby Museum
- Kentucky Kingdom & Hurricane Bay
- Churchill Downs
- Louisville Slugger Museum & Factory
- Valhalla Golf Club
- Muhammad Ali Center
- Louisville Slugger Field
- Angel's Envy Distillery
- L&N Federal Credit Union Stadium
- Kentucky Science Center
- Big Four Bridge
- Falls of the Ohio State Park
- Waterfront Park
- James B Beam Distilling
- University of Louisville
- Evan Williams Bourbon Experience
- Kentucky International Convention Center
- Frazier History Museum
- Bernheim Arboretum and Research Forest
- Jefferson Memorial Forest
- Marengo Cave National Landmark
- Bardstown Bourbon Company




