
House holiday rentals in Central Business District
Find and book unique houses on Airbnb
Top-rated house rentals in Central Business District
Guests agree: these houses are highly rated for location, cleanliness and more.

Sip Bourbon on the Custom Brick Patio at Heartpine and Soul
Enjoy the preserved history of Heartpine and Soul-- a restored retreat originally built in 1888. Heartpine floors, exposed red brick, and decorative fireplaces are combined with thoughtful displays of old wallpaper and news clippings. STR929290 Cleanliness has always been a top priority for us, and with the COVID-19 pandemic, we are taking additional measures to provide a safe, sanitary space for you. Enjoy the preserved history of this updated shotgun home, with details such as restored heartpine floors, exposed brick, and even thoughtful displays of old wallpapers and news clippings . HeartPine and Soul comes complete with a fully-equipped kitchen, a small deck, and a custom-built brick patio. The house has two bedrooms, each with a queen bed. Two full baths. And a sofa that converts to a queen bed. The house can accommodate a maximum of six guests. We offer a pack-and-play for those toting a tot with them. Very residential and historic neighborhood. Street parking, but not congested. We consider no pets, no parties, no loud noises, and no smoking. We also kindly request no shoes be worn in the house. Guests may access all parts of the house except for the garage. Enjoy the deck and back patio, but please be respectful of our established and welcoming neighbors. If you’d like to celebrate or party, please take it to many of Louisville’s breweries, restaurants, and distilleries that are abound in Butchertown and neighboring areas such as NULU and downtown! I love Louisville, and so will you! Inside HeartPine and Soul, there is a detailed guidebook to the house, neighborhood, and city, containing helpful information and tidbits. As a hostess, I offer lots of privacy, yet if you need assistance or even some dining recommendations, I’m a quick phone call or text message away! I also love communicating thru the AirBnB app. This is a historic residential area around the corner from Flying Axes, Goodwood Taproom, Quills Coffee, Naïve, and future site of the Louisville City Football Club stadium. HeartPine and Soul is central to the Urban Bourbon Trail-- a quick ride to Angel's Envy, Rabbit Hole, and Michter's Fort Nelson Distillery. Convenient location to KFC Yum! Center. Six miles to Churchill downs. Street parking, but not congested. Guests may park in front of the house. If you don’t have a car during your stay, Lyft and Uber are abundant in the Butchertown neighborhood. There’s also a bikeshare station called LouVelo, so you may pedal across town. The closest station is the west Butchertown station at Main & Clay. Some of the original landscape paintings in the home are by Mike Stevens and are for sale. HeartPine and Soul is another quality remodel project by Living Spaces By Lyn.

Nulu Liberty House
This beautifully updated home was named the #1 PET FRIENDLY Airbnb in Louisville by Trip101! Located in Louisville's hottest neighborhood, you'll be a short walk from a variety of restaurants, bars, local coffee shops, parks, bourbon distilleries and more! The kitchen and living room are inviting and fully stocked for you to relax with friends. All 3 bedrooms are spacious and comfortable and designed for you relax and make the most of your trip to beautiful Louisville. We can't wait to host you!

Bourbon Trail Spacious Backyard NEW HotTub Grill!
The Burnt Barrel, discover your vibrant Louisville getaway! Perfect for couples, business travelers, or event visitors, this cozy home offers high-speed Wi-Fi and a dedicated workspace, fully equipped kitchen, and a NEW hot tub and grill for you to enjoy! Guests rave about its comfort, walkable location, and modern amenities. Enjoy nearby bars and restaurants all just minutes from downtown, UofL Health, and the Convention Center. Experience true Louisville charm and convenience! Book a stay now!

Pool Table Getaway: Eclectic Vibes in Central Lou
An experience you can't get at a hotel! Your home is built around a full-size POOL TABLE — the place to reconvene & relax after a long day of excitement. We've decorated the house with plush king beds and furniture, a large & fully-stocked kitchen, eclectic art, 75" and 55" TVs, and room to breathe. Dog & kid friendly — your pup runs free in a fenced backyard. Dead-center in Louisville: NuLu, Churchill Downs, Waterfront Park, Bardstown Rd all close. Hands-off hosts, but always at your service!

Walking Bridge, Putt Putt House
NEW LISTING: Welcome to our walking bridge home on Pearl St. We have a hot tub, putt putt, and all the fun you can think of in one home. Steps away from restaurants, shopping, and bars, as well as the walking bridge to Louisville. This home is closer to the fun in Louisville than most neighborhoods in Louisville itself. Go out or stay in, you're guaranteed to have a great time in this newly renovated gem. We have high quality mattresses, and smart TV's in both bedrooms and the living room.

Hot Property! Music Fests- LTL, B&B, & KyDerby!
Shotgun Rye is ready to host your stay in Louisville! Located close to everything cool in Germantown and Highlands area! People visit for Bourbon Tours, Ky Derby, Conventions, Expo Ctr, UL graduations and sporting events, live music and so much more! Completely remodeled with all the modern conveniences & a comfortable, casual touch. But with so much to see and do in Louisville you’ll load up your itinerary with unforgettable experiences. Great location walk to bars, restaurants and shopping!

The Burb Inn - Nulu & Downtown *w/Firepit*
The Burb Inn is a hip place to stay in the Phoenix Hill/NULU district of Louisville. Easy access to top rated restaurants, bars, and attractions. Great place to host a group of friends, family or smaller bachelor party. Includes private parking, yard & fire pit. Upon entering there is a living area perfect for entertaining with 16’ ceiling & sleeping loft above the kitchen area. Upstairs has two bedrooms with queen beds each with private half bath. There is a separate private shower room.

Butchertown & NuLu's Shantyboathouse
Welcome to the Shantyboathouse! Recognized as a truly unique property, it has twice been featured in the Courier-Journal and was honored with a historical plaque by the Louisville Landmarks Commission in 2019. According to a 1976 newspaper article, a local legend recounts that the house floated up the river during the 1937 flood, and was later set on a foundation—earning it the enduring nickname, "the shanty boat." This rich history adds to the property's distinctive character and charm.

Heart of Louisville 3BR Getaway near Downtown
Welcome to your home in the heart of Louisville! This 3 bedroom, 2 bath space provides ample room for you and your guests. Nestled in the middle of NULU, the Highlands, and Downtown, you'll have central access to everything the city has to offer. Whether you're visiting Churchill Downs, exploring the Bourbon Trail, grabbing flights at Whiskey Row, or attending a summer concert, this is the perfect base for your adventures. Relax and create lasting memories in My Old Kentucky Home.

The Baxter IV - Family Friendly
This stylish place to stay is perfect for your trips! Located at the heart of Louisville, in a centenary house. Completely remodeled, cozy and the Louisville nightlife is just outside the door. In the morning, you can relax on the porch enjoying a cup of coffee. During your stay spend time walking the neighborhood filled with boutiques, restaurants, bars, distilleries and art galleries. Start the bourbon trail or walk to the famous Cave Hills Cemetery. Enjoy weird Louisville!

DOWNTOWN LOUISVILLE ⭐ Expo Center⭐ 3 BR, 2 BT
- 3 min drive to U of Louisville - 5 min drive to KY Expo Center - 7 min drive to Louisville Zoo This gorgeous 3-bed, 2-bath house is less than 4 miles from downtown Louisville. With its fully-equipped kitchen, spacious rooms & completely renovated kitchen, the house is the perfect base for large groups wanting to explore the city. Enjoy the wide variety of shops, restaurants, & bars nearby. Kentucky Derby fans love the close proximity to Churchill Downs. No Locals Please

Bourbon Trail Villa|King Suite|Fenced Backyard|BBQ
⚜1900 sq-ft of modern living space ⚜1,000 sq-ft of fully fenced outdoor entertainment space ⚜Weber grill, wood burning fire pit (wood included), huge swivel umbrella and outdoor dining for 6 ⚜Fully stocked Chef's kitchen ⚜Dry Bar ⚜Big Screen TV's in every bedroom ⚜Netflix Included ⚜Games & books for kids and adults ⚜3rd story office space with twin bed and city skyline views ⚜Urban bourbon trail ⚜Pet friendly! ⚜Minutes from Churchill Downs, Distilleries, & KY Expo Center
Popular amenities for house rentals in Central Business District
House rentals with a pool

Louisville KY Home w/Hot Tub & Pool

The Getaway!

DERBY! The Ville Getaway! Centrally Located

Pool*Pickleball Bldg*HotTub*Speakeasy*BourbonTrail

8 Min to Bourbon Fest | 6 Kings + Hot Tub

Top 1%• Yard + Porch • 3BR • Peppermint Cottage

CIRCO LOCO - uNCommon Stay

Close to everything / Huge
Weekly house rentals

Quiet Neighborhood Home With Outstanding Location

Lay Low B-Side | NULU | 2BR | Balcony

The Veranda

Derby City Bourbon Bungalow - by Germantown & UofL

Historic Hideaway w/Free Parking

Cheerful Highlands Home with Parking*Cherokee*NuLu

Modern stay for Derby minutes from Churchill Downs

New and modern ~Walkable~4 beds~Germantown
Private house rentals

Top Floor Penthouse at the Historic Levy Building

Bright & cozy Louisville home w/ private backyard

The Mashbill | Boutique Bourbon Retreat | Walkable

Stay in Historic Butchertown, Blocks From NuLu

Magical Fairytale Nulu - Historic 2BR Pet Friendly

Spacious Highlands Home-Sleeps 8, King Bed & Yard

Artistic Bungalow with Hot Tub

BarrelHaus | BourbonRetreat • Fire Pit • Near NULU
Quick stats about house rentals in Central Business District

Nightly prices starting at
Central Business District holiday rentals start at $270 SGD per night before taxes and fees

Verified guest reviews
Over 270 verified reviews to help you choose

Popular amenities for guests
Guests love Kitchen, Wifi and Pool across Central Business District rentals

4.9 Average rating
Central Business District stays are highly rated by guests – averaging 4.9 out of 5!

Nearby attractions
Central Business District’s top spots include Fourth Street Live!, Louisville Slugger Museum & Factory and Louisville Slugger Field
Destinations to explore
- Apartment rentals Downtown
- Fitness-friendly rentals Downtown
- Rentals with a washing machine and dryer Downtown
- Rentals with an accessible-height toilet Downtown
- Rentals with breakfast Downtown
- Flat rentals Downtown
- Rentals with a hot tub Downtown
- Hotel rooms Downtown
- Rentals with a firepit Downtown
- Rentals with a patio Downtown
- Waterfront rentals Downtown
- Rentals with an EV charger Downtown
- Loft rentals Downtown
- Rentals with outdoor seating Downtown
- Family-friendly rentals Downtown
- Rentals with pools Downtown
- Pet-friendly rentals Downtown
- House rentals Louisville
- House rentals Jefferson County
- House rentals Kentucky
- House rentals United States
- Buffalo Trace Distillery
- Kentucky Exposition Center
- Kentucky Derby Museum
- Kentucky Kingdom & Hurricane Bay
- Churchill Downs
- Louisville Slugger Museum & Factory
- Muhammad Ali Center
- Valhalla Golf Club
- Angel's Envy Distillery
- Louisville Slugger Field
- Big Four Bridge
- Kentucky Science Center
- Falls of the Ohio State Park
- Waterfront Park
- L&N Federal Credit Union Stadium
- Evan Williams Bourbon Experience
- James B Beam Distilling
- Kentucky International Convention Center
- University of Louisville
- Bernheim Arboretum and Research Forest
- Frazier History Museum
- Jefferson Memorial Forest
- Marengo Cave National Landmark
- Cherokee Park




