Guest house holiday rentals in Mount Pleasant
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Top-rated guest house rentals in Mount Pleasant
Guests agree: these guest house rentals are highly rated for location, cleanliness and more.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for guest house rentals in Mount Pleasant
Family-friendly guest house rentals
Guest house in Mount Pleasant
4.85 out of 5 average rating, 219 reviewsClose to beach , downtown and Shem creek
13–20 Jun
Guest house in North Charleston
4.94 out of 5 average rating, 346 reviewsCozy Park Circle, Charleston Guest House
12–19 Jul
Guest house in North Charleston
5.0 out of 5 average rating, 111 reviewsThe Park Circle Clerestory Studio Guest House
5–12 Jul
Guest house in Charleston
4.93 out of 5 average rating, 708 reviewsCharleston's Coolest Neighborhood
24–31 Aug
Guest house in Summerville
4.98 out of 5 average rating, 643 reviews★Delightful guest house near historic plantations★
10–17 Aug
Guest house in Summerville
4.94 out of 5 average rating, 212 reviewsNina's Cottage -Historic Downtown Summerville
23 Feb – 2 Mar
Guest house in Charleston
4.91 out of 5 average rating, 648 reviewsIsland Oasis—Near Downtown
21–28 Oct
Guest house in North Charleston
4.86 out of 5 average rating, 441 reviewsPark Circle Jungalow Loft
4–11 Jun
Guest house rentals with a patio
Guest house in Charleston
4.93 out of 5 average rating, 172 reviewsQuaint Cottage Studio in Ashley Forest (Avondale)
6–13 Jan
Guest house in Charleston
4.98 out of 5 average rating, 123 reviewsPrivate Backyard With Fire Pit, 15 Min to Downtown
15–22 Feb
Guest house in Charleston
4.97 out of 5 average rating, 127 reviewsStudio Apartment Minutes to Downtown Charleston
22–29 Dec
Guest house in Johns Island
4.91 out of 5 average rating, 105 reviewsCozy Cottage! 5 mins from Kiawah!
19–26 Jul
Guest house in Mount Pleasant
5.0 out of 5 average rating, 26 reviewsCoastal Charm: Village Hideaway
14–21 Dec
Guest house in Mount Pleasant
4.95 out of 5 average rating, 73 reviews*Old Village/Shem Creek Charmer*NEW 2BR Guesthouse
12–19 Oct
Guest house in Mount Pleasant
4.89 out of 5 average rating, 18 reviewsAdorable guest house with private backyard/patio
27 Aug – 3 Sep
Guest house in Hanahan
4.99 out of 5 average rating, 76 reviewsThe Violet Villa w/ no cleaning fee
6–13 Aug
Guest house rentals with a washing machine and dryer
Guest house in Summerville
4.97 out of 5 average rating, 216 reviewsTiny Oak Cottage in Historic Downtown Summerville
22 Feb – 1 Mar
Guest house in Charleston
5.0 out of 5 average rating, 216 reviewsJames Island "La Casita" Nestled btw Beach & City
17–24 Aug
Guest house in Charleston
4.98 out of 5 average rating, 244 reviewsDetached Guest Suite
20–27 Jan
Guest house in Charleston
4.99 out of 5 average rating, 142 reviewsLarge Guesthouse with Private Dock & Marsh Views
1–8 Jan
Guest house in Charleston
5.0 out of 5 average rating, 143 reviewsThe Guesthouse at Old Orchard
19–26 Sep
Guest house in Charleston
4.9 out of 5 average rating, 548 reviewsCute, Cozy, Charleston Cottage
12–19 Sep
Guest house in Charleston
4.96 out of 5 average rating, 237 reviewsUnique Hidden Gem w/ Luxury Shower Near Folly & DT
17–24 Jan
Guest house in North Charleston
4.94 out of 5 average rating, 111 reviewsNewly Renovated Studio in Park Circle
2–9 Jun
Quick stats about guest house rentals in Mount Pleasant
Total rentals
60 properties
Popular amenities
Kitchen, Wifi and Pool
Wifi availability
60 properties include access to wifi
Rentals with dedicated workspaces
20 properties have a dedicated workspace
Family-friendly rentals
10 properties are a good fit for families
Total number of reviews
5.7K reviews
Destinations to explore
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