House holiday rentals in Rochester

A cozy living area is featured, highlighting a brick fireplace with a warm glow. A marble countertop is positioned in the foreground, accompanied by two glasses of red wine and a plate of assorted fruit garnished with a purple flower. Natural light accentuates the scene.

4.92 out of 5 average rating, 196 reviews

The BEST Stay in Town: See Pics+Reviews to Believe

One level living/no stair. 2 bedrooms with 3 beds One-side of a duplex home: 1,200 Squarefeet w/ your own private entry, parking, laundry, kitchen.. 2.5 miles to Mayo, Target, Hyvee, gas stations...Fully furnished home. Smart TV & Fridge w/ Superfast internet & NetFlix included. Easy self-check-in keypad. A few blocks to the bus stop. Modern/spacious interior. Fully equipped kitchen w/ dishwasher, pots, pans, and washer/dryer at no additional cost. Fireplace & private deck. 3 parking spaces

A cozy living area features a patterned sofa with a red accent pillow, complemented by warm wooden flooring. A brick wall provides texture, and natural light filters through the windows. In the background, a dining area with a wooden table and chairs can be seen, along with a staircase.

4.97 out of 5 average rating, 117 reviews

Cottage in Lowertown–Perfect for Mayo & Downtown

In Lowertown-this quaint cottage with modern updates is your home away from home! Fully furnished and a well stocked kitchen make it a wonderful place for overnight stays or longer term rentals. Beautiful patio provides an urban sanctuary at the end of a long day. Close proximity to Mayo Clinic-downtown restaurants, grocery stores and shopping are within walking distance. Two blocks in either direction puts you on the trail system. Public transit 1 ½ blocks away and a laundromat is ½ block away.

A spacious living area features warm wood beam ceilings and large windows, allowing natural light to fill the room. Modern furniture, including a comfortable white sofa and a glass dining table, is arranged to create an inviting space. Double doors lead to a backyard patio.

4.95 out of 5 average rating, 269 reviews

Euro House, Bright! Near Mayo-Single Family Home

Welcome to your home away from home! This private, single-family home was thoughtfully designed and is located in a quiet area just 5 minutes (0.9 miles) from the Mayo Clinic. Step into a master gardener’s dream—a beautifully landscaped yard filled with native plants and outdoor seating, perfect for relaxing after a long day. 2 Queen Bedrooms, 2 Full Bathrooms, modern finishes throughout, Super clean and pet-free. Off-street parking, Washer & dryer, Wi-Fi, Smart TVs & Fully stocked kitchen.

4.97 out of 5 average rating, 154 reviews

Charming 3BR family home - 8 min drive to Mayo

Your home away from home. Cozy 3 BR, 3 beds + futon, 1.5 bath home located centrally in Rochester. Approximately 2 miles from Mayo & St. Mary’s hospital, 700 ft to nearest small grocery store, 0.6 miles to nearest gas station, and 1.5 miles to nearest shopping area w/Target, Chipotle, Applebee’s & more. Close to the Bus lines, bike trails & parks. This home is in the center of the city and is easily accessible. Come home and relax in a quiet, quaint neighborhood. All bedrooms on top floor.

A single-story home is shown, featuring a red front door and a well-maintained exterior. Vibrant autumn trees with golden leaves line the walkway, and a grassy area is depicted in front of the house, inviting a sense of tranquility to the setting.

4.87 out of 5 average rating, 414 reviews

Mayo Downtown's Prairie Home Retreat

Nestled in a serene corner, this home offers a perfect blend of tranquility and accessibility; being near the Mayo campus and Rochester's key attractions. Enjoy comfortable beds, a well-appointed kitchen, and a fenced yard with patio gardens. It's an excellent spot for family bonding, featuring three smart TVs, rapid Wi-Fi, and a variety of indoor and outdoor entertainment options. We strive to accommodate flexible check-in/check-out arrangements whenever feasible. Rollator accessible.

The living room features a gray sofa adorned with soft pillows, paired with two chair seats. A wooden coffee table sits atop a decorative rug, while a television on a white stand displays a serene nature scene. Light filters through sheer curtains, enhancing a calm atmosphere.

4.85 out of 5 average rating, 296 reviews

Coastal Charm w/Jacuzzi Tub-8min to Mayo

Recently restyled/refurnished in March 2024. Coastal and a bit of boho, cozy single-family, styled to be your home away from home. 8 Min to Mayo & 7 Min to St. Mary's. Relax after a long day in a Jacuzzi tub. Equipped with various kitchen appliances and utensils (No Dishwasher). Short drive to parks, groceries & shopping. Smart TV & veggie garden. We're a phone call away if you have any needs. Relax on the deck, enjoy a cozy campfire. No pets due to Mayo Clinic guests’ allergies.

Home in Historic Southwest

The open-concept living area showcases vaulted ceilings and skylights, enhancing natural light. Two light grey sofas frame a wooden coffee table on a colorful area rug. A dining area with a large table and chairs is visible, with stairs leading to the upper level in the background.

4.97 out of 5 average rating, 195 reviews

Spacious Modern Home Near Mayo, St. Mary's Campus

- 5 min walk to Mayo Clinic, St. Mary’s campus - 3 bedrooms, 3 bathrooms, and a loft - unique design with vaulted ceiling and skylights in the style of Frank Lloyd Wright, one of its kind in the whole neighborhood - two-car garage + another dedicated parking space outside - walkable and safe family-friendly neighborhood close to downtown and all amenities - outside front and back patios - fusball play table - dedicated workspace - high speed wifi - Apple TVs - washer and dryer

The living area is highlighted by a modern gray sofa, accentuated with textured cushions. A sleek coffee table holds a glass vase with greenery, while art pieces adorn the wall. Natural light filters through sheer curtains, creating a bright and inviting space.

4.97 out of 5 average rating, 146 reviews

Entire Boutique Home Kutzky Park ★ Walk to Mayo ★

Welcome to Asfar house! Expertly designed and centrally-located in a desirable Kutzky Park neighborhood, walking distance to Mayo Clinic, restaurants and shops. Whether you are relocating or visiting Rochester, this house will be sure to impress. Blasting fast WIFI, 3 relaxing bedrooms & a fully equipped kitchen. A perfect retreat to enjoy the coffee bar, read, watch a Netflix episode, play and relax. Enjoy the perfect shower, conveniently adjoined with free washer and dryer.

A dining area is showcased with a wooden table surrounded by six chairs, highlighting a welcoming space for meals. Natural light filters through the open doorway, illuminating the adjacent living room, which features a comfortable sofa and a front door with glass panes.

4.91 out of 5 average rating, 156 reviews

Entire Spacious House, 1/2 block from St. Marys

Older charming home! Less than one block from St. Mary's hospital. Ideal space for clinic patients and their families. Entire residential home with on-site parking for up to 3 cars. Located in the heart of Rochester Minnesota, within walking distance to Mayo Clinic and many necessities such as grocery stores, coffee shops, mayo shuttles, and restaurants. This location is a perfect home away from home, fully stocked kitchen, comfortable beds, and lots of room to spread out!

A cozy bedroom features slanted ceilings with soft gray walls. A spacious bed is adorned with a striped gray and white blanket, flanked by two nightstands with lamps. Art pieces decorate the walls, and a window allows natural light to illuminate the room.

4.87 out of 5 average rating, 531 reviews

Cottonwood Cottage

This beautiful 3 bedroom home is just 12 blocks from Mayo. It has plenty of space for your family. It has a nice kitchen with quartz counters. It also has a large living room with game corner, work area and Roku TV for all your streaming services. The home is located on the end of a quiet street and access to Rochester's vast walking/biking trails starts right out the front door. There is also a back patio with seating and a gas grill.

A bright bedroom features a spacious bed with white linens and a decorative pillow. A bedside lamp emits soft light beside a window with light curtains. A green dresser and a mirror complement the neutral walls, adding a fresh touch to the space.

4.97 out of 5 average rating, 385 reviews

The Guesthouse Cottage, walkable to Mayo Clinic

Our Guesthouse has a clean cottage feel. The king and queen bedrooms offer closets and quality linens. Cook meals in a fully stocked kitchen. Book an Uber, or walk 0.6 miles to Mayo's main Gonda building. We're close to grocers, coffee, parks and trails, and downtown's restaurants, shops, and a lovely public library. Free washer and dryer on site. Google TV and internet. 3-season porch. Small guest garage. No smoking on the property.

4.96 out of 5 average rating, 175 reviews

The Sierra! Close to Mayo Clinic

Gorgeous Home close to Mayo Clinic. The family room and living include Roku 4K UHD TVs, Foosball, and darts. Free WIFI. Office on Main with great light. Beautiful front porch or patio in the rear. TVs Enjoy luxurious finishes like crown molding, a fireplace in the family room, quartz countertops and a stunning vaulted Primary Ensuite with custom tile work and paneled doors. All of this is conveniently just minutes from downtown!

Popular amenities for house rentals in Rochester

Kitchen

Wifi

Pool

Free parking on premises

Air conditioning

House rentals with a pool

The exterior of a modern two-story home showcases a contrasting black and white color scheme. A spacious driveway leads to a large, white garage door. Clear blue skies serve as a backdrop, and well-maintained landscaping frames the property.

4.86 out of 5 average rating, 7 reviews

4bd/2.5bth Single-Family Home Close to Mayo

A modern two-story single-family home is depicted, featuring a clean white and black exterior. A large garage door complements the ample driveway. The well-maintained lawn offers a green backdrop, while the sunlit blue sky enhances the overall inviting appearance of the property.

5 out of 5 average rating, 9 reviews

4bd/2.5bth Single-Family Home Close to Mayo

Superhost

A modern single-family home is depicted, featuring a sleek black exterior with a prominent garage. The driveway leads to a well-maintained lawn, flanked by young trees and ornamental grasses, creating an inviting entrance. Clear blue skies complete the serene setting.

5 out of 5 average rating, 5 reviews

Unit 2377J | 3bd/2bth | Single-Family Home

A serene outdoor space is highlighted by a stunning sunset over lush greenery. Comfortable seating is arranged around a fire pit, surrounded by blooming flowers and various plants. A swimming pool is visible in the background, nestled into the landscape.

5 out of 5 average rating, 47 reviews

RARE! Pool, hot tub, garden &chickens! 4m to Mayo

A modern single-family home showcases a dark exterior with a spacious two-car garage. The front yard is neatly landscaped, featuring green grass and a young tree. A covered porch provides shaded entry, with large windows allowing natural light to stream indoors.

5 out of 5 average rating, 13 reviews

Unit 2365J | 2bd/2bth | Single-Family Home

Weekly house rentals

A modern kitchen features sleek white cabinetry and a matching countertop. Essential appliances, including a black stove, microwave, and stainless-steel dishwasher, are present. Natural light enters through a window above the sink, which is adorned with stylish fixtures and greenery for a touch of freshness.

4.92 out of 5 average rating, 38 reviews

Modern 2 Bd Close to Downtown / Mayo, free parking

A comfortable living area is showcased with a spacious sectional sofa and a small side table. Natural light fills the space through large windows, and a dining area is visible in the background. Decorative plants add a touch of greenery to the inviting environment.

5 out of 5 average rating, 28 reviews

The Little Blue Inn

Home in Historic Southwest

A charming two-story home featuring a yellow exterior with white trim and a dark blue front door. The entrance is framed by decorative windows and is surrounded by lush greenery and autumn leaves. A concrete walkway leads up to the front steps.

4.89 out of 5 average rating, 19 reviews

Oasis by the Mayo Clinic

Superhost

A light-filled living room features a soft beige sofa with blue accent pillows. Two teal chairs with decorative pillows are positioned nearby. A small coffee table is centered in the room, with a mirror and lamps providing ambient lighting. Large windows offer views of the outside.

4.86 out of 5 average rating, 7 reviews

Gorgeous Rochester-Mayo Clinic Home

A bright kitchen area is featured, showcasing wooden cabinetry with glass-front doors. A modern black faucet is positioned over a neutral countertop, and a welcoming sign decorates the wall above. Natural light filters through the window, illuminating the backsplash tiles.

4.94 out of 5 average rating, 71 reviews

The Cozy Hope House -- Minutes from Mayo Clinic

The exterior of a historic home is displayed, featuring a welcoming porch with a green front door. A spacious lawn surrounds the house, complemented by trees and neighboring structures visible in the background. The roof has distinctive angles, adding to the property’s character.

4.98 out of 5 average rating, 61 reviews

Large 4 Bedroom Downtown Home JUST BLOCKS TO MAYO

4.94 out of 5 average rating, 18 reviews

Cozy home, close to Mayo Clinic!

A charming single-family home with a light green exterior is featured. A concrete pathway leads to the front door, bordered by a well-maintained grassy area. A mailbox stands at the entry, and green waste bins are positioned nearby. The roof has a gable design, enhancing the home's character.

4.93 out of 5 average rating, 41 reviews

“2BR 2BA– Walk to downtown, Silver Lake

Private house rentals

The kitchen features modern cabinetry with a blend of light and dark tones. A wooden breakfast bar with black stools provides seating, while stainless steel appliances and a large window allow natural light to fill the space. A patterned tile floor adds visual interest.

4.99 out of 5 average rating, 70 reviews

The Cozy Blue Haven: 1 mi to Mayo

A modern kitchen space is showcased with sleek, dark cabinetry and stainless steel appliances. An island with seating for two is centered, complemented by a reclining chair nearby. Soft lighting enhances the overall space, creating a functional cooking and dining area.

5 out of 5 average rating, 54 reviews

Beautifully Designed Space. 1 Mile to Mayo Clinic

The living area features a comfortable sofa and armchair beside a large window, offering views of the surrounding nature. A coffee table sits centrally, adorned with a decorative plant. Light fixtures hang from the ceiling, providing a warm ambiance.

5 out of 5 average rating, 23 reviews

House in the trees with City View (Haakon House)

4.89 out of 5 average rating, 46 reviews

Quarry Hill Home

Home in Downtown Rochester

4.95 out of 5 average rating, 21 reviews

Relax & Recharge-3BR w/garage 3 blocks To Mayo!

Superhost

A welcoming living area features a comfortable leather sofa and an armchair, arranged on a soft area rug. A fireplace adds a classic touch, while the large windows allow natural light to illuminate the space. French doors lead to a cozy seating area in the background.

4.94 out of 5 average rating, 34 reviews

Charming Tudor Home 3 blocks from Mayo Clinic

A spacious living area is furnished with two comfortable sofas, a coffee table, and a flat-screen television. Natural light enters through large windows adorned with light curtains, and a ceiling fan provides a cooling breeze. A welcoming entrance with a modern door is visible.

5 out of 5 average rating, 36 reviews

Quaint Home 2 miles from Mayo

A cozy bedroom is presented with a spacious bed featuring a light-colored headboard. Decorative pillows in shades of blue and yellow are arranged neatly on the bed. Two bedside tables with stylish lamps flank each side, while a large ocean-themed painting adds a tranquil touch to the wall.