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Apartment holiday rentals in Santee

Find and book unique apartments on Airbnb

Top-rated apartment rentals in Santee

Guests agree: these apartments are highly rated for location, cleanliness and more.

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Superhost
A wooden dock extends over the tranquil waters, framed by trees with golden leaves. Boats are visible at the floating slips, surrounded by lush greenery and a peaceful lake setting.
Flat in Santee
4.81 out of 5 average rating, 27 reviews

Dockside Villa Lake Marion

Dockside Villa on lake Marion includes a boat slip just out the back door of condo. 1 king, 1 Queen: 2 private beds and 2 baths plus pull out sofa bed in living room. Condo is fully furnished which means it will sleep up to six comfortably for a family/friends, golfing-lake adventure. Bring your boat - keep it at the dock during your stay or rent a boat next door. The amenity package includes outdoor grills, walking trails, and a boat landing. 3 world class golf courses are 3 to 5 minutes away.

Top guest favourite
Flat in Summerville
4.95 out of 5 average rating, 43 reviews

*Amazing Azalea Bar Secret Garden Apartment

Stay in the Heart of Downtown Summerville! Perched above The Azalea, a sophisticated cocktail bar, this historic suite offers the ultimate downtown location and comfort that cannot be beat! Blending modern amenities with southern charm, it’s perfect for those who love being in the center of it all. Step outside & explore all that Flowertown has to offer-eclectic shops & fantastic restaurants or, take a short trip to Charleston & or our fantastic beaches. Book your unforgettable stay today!

Top guest favourite
Flat in Moncks Corner
5 out of 5 average rating, 37 reviews

Cozy escape studio apartment

Welcome to your perfect little retreat! This cozy studio apartment is nestled in the vibrant heart of our charming small town, just steps away from local shops, cafes, parks, and everything you need for a comfortable visit (See guidebook). We are minutes from several boat ramps on the lake and river listed in the guidebook. We have plenty of space in our driveway for you to bring your boat! 🚤 This is also a perfect extended stay space for traveling nurses and respiratory therapists! 🩺

Guest favourite
A private entrance to the guest quarters is framed by lush greenery and potted plants. The entrance features double doors with multiple panes, leading into a welcoming atmosphere. A small welcome mat is positioned at the door, complemented by a light-colored chair nearby.
Flat in Summerville
4.82 out of 5 average rating, 11 reviews

Private Guest Quarters at Linwood - 1 bed/1 bath

The Private Guest Quarters at Linwood is a cozy 1 bed/1 bath apartment located beneath the main house at Linwood, Historic Home and Gardens, a 2-acre Victorian era estate built in 1883. The apartment has its own private entrance and is equipped with a small kitchen, a dining area, one bedroom, one bathroom and a washer/dryer. Amenities include Cable TV, free Wi-Fi, bed linens, bath towels and off street parking. A unique, comfortable and private living experience for one or two guests!

Top guest favourite
An A-frame structure is pictured, elevated on a brick foundation. Sturdy wooden stairs lead to the entrance, flanked by a deck with railings. The surrounding area is filled with tall trees, and a car is parked underneath the apartment, offering a rustic country setting.
Flat in Orangeburg
4.99 out of 5 average rating, 168 reviews

Elevated Country Apartment

Discover the charm of country-living in our cozy 1-bedroom elevated apartment, just a short drive from Orangeburg, Bamberg, and Neeses. Wake up to the sound of roosters crowing and enjoy your morning coffee with views of our picturesque homestead, or enjoy a glass of wine while watching the sun set below the majestic pines. Perfect for those seeking tranquility without sacrificing convenience, our apartment offers a fully-equipped kitchen and laundry.

Guest favourite
A serene lakeside view is captured at sunset, displaying a colorful sky with hues of orange, pink, and blue. The calm water reflects the clouds, adding to the tranquil atmosphere. A wooden dock extends into the lake, enhancing the peaceful setting.
Flat in Moncks Corner
4.82 out of 5 average rating, 17 reviews

Ophir Oasis Unit #3

Stylish, clean, and Simplistic Studio Apartment at Locklairs Landing. Unit 3 offers a perfect blend of comfort and simplicity. This studio, 1-bath is ideal for relaxing or working remotely. As well as a kitchen area fully equipped with apartment sized appliances. The property is perfect for swimming, fishing, or taking in the scenery. If you're seeking a quiet getaway or active retreat, our apartment at Locklairs Landing offers a lakeside oasis.

Superhost
A serene lakeside view is presented, featuring multiple building levels illuminated softly by exterior lights. A wooden dock extends towards the water, surrounded by lush greenery and trees, creating a peaceful atmosphere along the shoreline.
Flat in Santee

3-Bedroom Dlx @ Lake Marion Resort

You'll have a great time at this comfortable place to stay. When a trip calls for water and the ocean won’t do, a lake retreat is just the thing. Escape the everyday at this peaceful retreat located on Lake Marion’s Chapel Branch. Explore South Carolina’s largest lake, or discover other adventures like horseback riding, mountain biking, or hiking. And if the greens are more your thing, the area is brimming with exceptional golf courses, too.

Superhost
The image displays a multi-story building with large windows, surrounded by autumn trees featuring vibrant orange leaves. A dock is visible in front, with a red kayak resting on the water, reflecting the calming lake environment.
Flat in Santee

Lake Marion Resort 1 Bedroom Unit

Take a break and unwind at this peaceful oasis. When a trip calls for water and the ocean won’t do, a lake retreat is just the thing. Escape the everyday at this peaceful retreat located on Lake Marion’s Chapel Branch. Explore South Carolina’s largest lake, or discover other adventures like horseback riding, mountain biking, or hiking. And if the greens are more your thing, the area is brimming with exceptional golf courses, too.

Superhost
An outdoor balcony features a dining table surrounded by four mesh chairs. A ceiling fan is visible above, and the view includes a serene lake framed by trees under a clear blue sky.
Flat in Santee
4.83 out of 5 average rating, 35 reviews

Relaxation is the plan

Come and relax in this peaceful retreat. A beautiful view of the lake and the sunset from the comfort of the living area or outside on the spacious balcony, a stunning lakefront property offering breathtaking views. This meticulously maintained 2-bedroom, 2-bathroom condo is centrally located off I-95, providing both privacy and convenience. The serene lake views and well-kept interiors create a peaceful retreat for relaxation.

Superhost
A wooden dock extends over calm waters, with a small boat resting at the edge. Surrounding trees display vibrant autumn foliage in shades of orange and red, reflecting on the water's surface under a clear blue sky with soft clouds.
Flat in Santee

Lakeside Bliss 2BR/2BA Suite Wyndham Lake Marion

Escape to lakeside bliss at our spacious 2-bedroom, 2-bathroom resort suite located in the serene Wyndham Lake Marion. Embrace the tranquility of the picturesque surroundings as you unwind in this comfortable retreat. Book your stay at our lakeside 2BR suite and experience the perfect blend of relaxation and adventure at Wyndham Lake Marion. Create unforgettable memories in this scenic oasis.

A serene view captures a community pool bordered by lush greenery and palm trees. The lake reflects a pastel sunset, enhancing the tranquil atmosphere. Chairs are arranged around the pool, inviting relaxation. A well-maintained pathway leads through the landscape towards the water's edge.
Flat in Santee
4.83 out of 5 average rating, 6 reviews

Lake and pool side vacationing

Bring the whole family to this great place with lots of room for fun. community pool just a few steps away and the biggest lake in SC right behind it and a sandy cove a couple hundred feet way. Bring or rent a boat and use the private boat landing and a dock to tie off. Condo is probably the nicest in the building!

Guest favourite
A comfortable seating area is highlighted by a light grey sofa adorned with a patterned throw. Two vintage chairs frame a small coffee table, which is topped with books. Natural light filters through an arched window with a softly shaded blind.
Flat in Elloree
4.86 out of 5 average rating, 22 reviews

Modern apartment overlooking a Historic Downtown

Relax at this peaceful and centrally-located getaway in the heart of historic Elloree, SC. Just minutes away from Santee, I95, I26, fishing and golfing, it's perfect for a quiet weekend getaway, business trip or staycation! Free electric car charging available for your convenience upon request.

Popular amenities for Santee apartment rentals

Quick stats about flat rentals in Santee

  • Total holiday rentals

    Explore 10 holiday rentals in Santee

  • Nightly prices starting at

    Santee holiday rentals start at $192 SGD per night before taxes and fees

  • Family-friendly holiday rentals

    10 properties offer extra space & child-friendly amenities

  • Holiday rentals with a pool

    10 properties feature pools

  • Rentals with dedicated workspaces

    10 properties have a dedicated workspace

  • Wifi availability

    10 of Santee holiday rentals include wifi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi and Pool across Santee rentals