
Apartment holiday rentals in Panama City
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Top-rated apartment rentals in Panama City
Guests agree: these apartments are highly rated for location, cleanliness and more.

Modern apartment in the heart of Obarrio
This apartment stands out for its prime location in Obarrio, with a modern and cozy design. Located on the 14th floor, it offers a spectacular view, its decoration in neutral tones conveys serenity. The comfort of having two bathrooms makes it unique. Ideal for travelers looking for tranquility and functionality. Located within walking distance of Calle 50 and the iconic El Tornillo building. You're surrounded by casinos, hotels, and restaurants. Safe area to walk and enjoy the city.

Chic Studio in Casco Antiguo - View to Main Plaza
Located in trendy Casco Antiguo, this studio apartment is walking distance of restaurants, cafes, supermarkets, pharmacies and the overall life of Casco. The building has recently been renovated and has a beautiful view of Plaza Catedral. Note: As seen on previous comments, there used to be a bar club in the rooftop and at the bottom of the building. Good news, there are no more bars in the building and the studio has soundproof doors as Casco is an area with the best nightlife in Panama.

Ocean View private Studio Apartment
The Sands Avenida Balboa, diseñado y pensando en el Viajero activo y aventurero, The Sand Avenida Balboa cuenta con apartamentos tipo estudio amueblado y con acabados, cada apartamento cuenta con una pequeña cocina, baño privado, armario y muebles cómodos; incluyen ventanas de piso a techo. The Sand Avenida Balboa está idealmente ubicado en el corazón de la ciudad de Panamá, Avenida Balboa con fácil acceso al centro, al Casco Antiguo y a menos de 5 minutos de Causeway y el Biomuseo.

Escape to the Heart of Casco with a Private Balcony
Location is everything – just steps away from the city’s best restaurants, bars, stunning churches, and fascinating museums. Explore the historic district on foot while enjoying the comfort of a stylish apartment featuring: • A spectacular balcony with beautiful views • A fully equipped kitchen • 1.5 bathrooms • Cozy beds that make you feel right at home • Surrounded by iconic calicanto stone walls that reflect the charm of Panama’s colonial past.

Amazing loft with an iconic view of Casco Viejo
Enjoy a unique experience, in this elegant and centrally-located loft. Fully remodeled 1 bedroom apartment, in a central location in Casco Viejo (the old city). You will be just steps away from many restaurants, cafes, museums, and the existing night life casco has to offer. Located in “Jeronimo,” this restored- colonial building was built in the year 1850, and features unique crafted wall décor, as well as some of the original "calicanto" walls.

Private parking & rooftop | Studio Casco Center
This beautiful restored studio from the 1870s blends history with modern design. Enjoy a private rooftop terrace with seating and BBQ, plus private PARKING—ideal after exploring Casco's best restaurants, galleries, and nightlife steps away. ✨ Highlights: - Historic Charm: Original tile floors and exposed colonial stone walls. - Comfort: King bed, living room, and full kitchen. - Amenities: Private rooftop & private PARKING. - Great location

Cozy Studio in Cinta Costera with Home Vibes
✨ Live the "Cinta Costera Vibes" experience 🌴 from this modern studio apartment with a panoramic view of the Bay and the vibrant Balboa Avenue. Perfect for travelers looking for comfort, style, and a premium location. Enjoy the pool, restaurant, gym, and rooftop with the best sunset in Panama 🌅. Ideal for short or long stays — your home with home warmth and a 5⭐ touch. Save it as a favorite and live the Host Up experience!

Luxury apartment in downtown Panama, banking area
We have a strategic location right on the main road of Panama (Calle 50) Bella Vista. You will find yourself located in the heart of the banking area. Whether you're coming for work or vacation, this is the ideal place. You'll find all kinds of restaurants, shops, and shopping malls nearby. You'll have the Cinta Costera just a 10-minute walk away where you can walk or exercise. Fun and enjoyment within walking distance

k*| Delightful 1 BR w/King Bed in Calle 50
Calle 50 es el Times Square de la Ciudad de Panamá. Esta emblemática calle resguarda a la concurrida Area Bancaria. La ubicación del apartamento es excepcional y céntrica, cercana a: ->Estación Iglesia del Carmen [Línea 1 del Metro de Panamá] ->Cinta Costera ->Parque Urracá ->Supermercado Rey ->F&F Tower (Edificio del "Tornillo") ->Nightlife en Calle Uruguay Desde el piso 19 se ofrecen vistas a la ciudad y a la selva.

Full apartment in Panama
This charming apartment is located in one of the best neighborhoods in Panama, San Francisco, a downtown location where you will find ample cuisine, entertainment venues, close to bus stations, and the city's most important shopping mall, Multiplaza. This central and quiet apartment is an opportunity you won't want to miss. It offers the perfect combination of comfort, beauty, and a convenient location.

Jacuzzi in colonial ruins in beautiful apartment
Welcome to Casa Marquez Portazgo! This cozy apartment in the heart of Panama City offers comfort and convenience, ideal for your stay. With one bedroom and capacity for two people, you'll enjoy a relaxing atmosphere in 70 m². Located in the San Felipe neighborhood, just steps from the entrance to the Casco Antiguo, it offers a unique experience. You can also unwind in the jacuzzi.

Elegant apartment with a view & the warmth of home
This apartment with the warmth of home, elegant and comfortable with spectacular views of the city, located in one of the best areas of Panama City, surrounded by places of interest such as restaurants, commerce and the most important banking area of the city, and its proximity to the Iglesia del Carmen metro station provides easy transportation in and out of Panama City.
Popular amenities for Panama City apartment rentals
Weekly apartment rentals

Beautiful apartment in Casco Viejo ST. George D

Cozy apartment in Panama

A cozy Casco Viejo apartment

Luxury Centric 2BR Apartment in Casco Viejo

Suite Luxury 30th View , Cinta Costera Panama

Brand new 1B 1B apartment in a vibrant area

Serena House Obarrio by God Housing

Urban Suite in front of Sortis Hotel, Downtown
Private apartment rentals

Oceanview 1BR in Yoo Panama

Centrally located apartment.

Best Location, Beautiful Apartment, Panama

Poin apartment ocean view + pool + gym

Apartment 20B YOO Ocean View on Balboa Avenue

Unique Luxury 3-story Loft at the Yoo

1bd/2Bthrm East Coast-Panama

The black and white home. PH living 73 . Apto 10J
Apartment rentals with a hot tub

Luxury Apartment in Panama | 2BR + Views + Pool

PH Yoo 44i – Ocean View Apartment

New Flat with Ocean + City Views

Spacious Oceanfront Apartment

Coastal View Executive Studio in Panama City

Tropical Paradise at Playa Bonita

Panama Dream View Escape

On the beach. Entire floor with oceanfront terrace
Quick stats about flat rentals in Panama City

Total holiday rentals
Explore 2,890 holiday rentals in Panama City

Nightly prices starting at
Panama City holiday rentals start at $13 SGD per night before taxes and fees

Verified guest reviews
Over 79,200 verified reviews to help you choose

Family-friendly holiday rentals
900 properties offer extra space & child-friendly amenities

Pet-friendly holiday rentals
Find 1,090 rentals that welcome pets

Holiday rentals with a pool
1,840 properties feature pools

Rentals with dedicated workspaces
1,770 properties have a dedicated workspace

Wifi availability
2,760 of Panama City holiday rentals include wifi access

Popular amenities for guests
Guests love Kitchen, Wifi and Pool across Panama City rentals

4.7 Average rating
Panama City stays receive an average rating of 4.7 out of 5 from guests

Nearby attractions
Panama City’s top spots include Miraflores Locks, Museo de Arte Contemporáneo and Santo Tomas (Panama Metro)
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