
Apartment holiday rentals in Panama City
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Top-rated apartment rentals in Panama City
Guests agree: these apartments are highly rated for location, cleanliness and more.

In the heart of Casco, refurbished and with parking
Escape and discover the old town in this remodeled, comfortable and central accommodation in the heart of Casco Viejo. Our location is the best, it will make you come back. Close to restaurants, bars, impressive churches, and museums. The property dates back to the 17th century (1756) history and good atmosphere. You can explore the area on foot, fully equipped kitchen, European king bed, you will feel right at home, surrounded by the famous calicanto walls. -A large living room -Fully-equiped kitchen

Modern apartment in the heart of Obarrio
This apartment stands out for its prime location in Obarrio, with a modern and cozy design. Located on the 14th floor, it offers a spectacular view, its decoration in neutral tones conveys serenity. The comfort of having two bathrooms makes it unique. Ideal for travelers looking for tranquility and functionality. Located within walking distance of Calle 50 and the iconic El Tornillo building. You're surrounded by casinos, hotels, and restaurants. Safe area to walk and enjoy the city.

private ocean view studio apto.
The Sand Avenida Balboa cuenta con apartamentos tipo estudio de 24 metros, amueblado y con acabados, cada apartamento cuenta con una pequeña cocina, baño privado, armario y muebles cómodos; incluyen ventanas de piso a techo. The Sand Avenida Balboa está idealmente ubicado en el corazón de la ciudad de Panamá, Avenida Balboa con fácil acceso al centro, al Casco Antiguo y a menos de 5 minutos de Causeway y el BiomuseoDisfruta de una experiencia con estilo en este alojamiento céntrico.

Remote Working • Rooftop Pool Gym • NearMultiplaza
➤ Nice apartment with balcony, nestled conveniently near Multiplaza Mall . ★ Perfect for Remote Workers, desk with chair to work, 750 MB internet speed, 100 Up. ★ Walk 5-10 mins to Restaurants, Supermarkets, Multiplaza Mall, Cafes & Entertainment. ➤ Urban Escape - Building Highlights: ★ State-of-the-art Gym ★ 2 Co-Working Spaces, 500 MB speed internet. ★ Chlorine-free Pool on the Rooftop Terrace. ➤ Located in Central San Francisco: Explore the City Easily | Uber-Friendly

Amazing loft with an iconic view of Casco Viejo
Enjoy a unique experience, in this elegant and centrally-located loft. Fully remodeled 1 bedroom apartment, in a central location in Casco Viejo (the old city). You will be just steps away from many restaurants, cafes, museums, and the existing night life casco has to offer. Located in “Jeronimo,” this restored- colonial building was built in the year 1850, and features unique crafted wall décor, as well as some of the original "calicanto" walls.

Luxury apartment in Panama, ocean view
Located in San Francisco, one of Panama's exclusive areas par excellence, where gastronomy, history, modernity, and entertainment magically combine. Wonderful location near must-see destinations, gym, swimming pool, co-working, pet spa, and terrace. Parking is charged. Modern and functional, this apartment features a queen-size bed, fully-equipped kitchen, Wi-Fi, TV, a spectacular balcony with ocean views, laundry center, and sofa bed.

Cozy Studio in Cinta Costera with Home Vibes
✨ Live the "Cinta Costera Vibes" experience 🌴 from this modern studio apartment with a panoramic view of the Bay and the vibrant Balboa Avenue. Perfect for travelers looking for comfort, style, and a premium location. Enjoy the pool, restaurant, gym, and rooftop with the best sunset in Panama 🌅. Ideal for short or long stays — your home with home warmth and a 5⭐ touch. Save it as a favorite and live the Host Up experience!

k*| Delightful 1 BR w/King Bed in Calle 50
Calle 50 es el Times Square de la Ciudad de Panamá. Esta emblemática calle resguarda a la concurrida Area Bancaria. La ubicación del apartamento es excepcional y céntrica, cercana a: ->Estación Iglesia del Carmen [Línea 1 del Metro de Panamá] ->Cinta Costera ->Parque Urracá ->Supermercado Rey ->F&F Tower (Edificio del "Tornillo") ->Nightlife en Calle Uruguay Desde el piso 19 se ofrecen vistas a la ciudad y a la selva.

Full apartment in Panama
This charming apartment is located in one of the best neighborhoods in Panama, San Francisco, a downtown location where you will find ample cuisine, entertainment venues, close to bus stations, and the city's most important shopping mall, Multiplaza. This central and quiet apartment is an opportunity you won't want to miss. It offers the perfect combination of comfort, beauty, and a convenient location.

New Apartment in Panama City
Explore Panama City with style from our luxurious 1-bedroom apartment in San Francisco. The apartment is brand new and designed specifically for your comfort. Ideal for 2 guests, with a private bedroom, fully equipped kitchen, and a balcony with city views. Building amenities include a pool, gym, co-working center, and 24-hour security. Near shopping, dining, and Parque Omar. Book your stay today!

Jacuzzi in colonial ruins in beautiful apartment
Welcome to Casa Marquez Portazgo! This cozy apartment in the heart of Panama City offers comfort and convenience, ideal for your stay. With one bedroom and capacity for two people, you'll enjoy a relaxing atmosphere in 70 m². Located in the San Felipe neighborhood, just steps from the entrance to the Casco Antiguo, it offers a unique experience. You can also unwind in the jacuzzi.

Elegant apartment with a view & the warmth of home
This apartment with the warmth of home, elegant and comfortable with spectacular views of the city, located in one of the best areas of Panama City, surrounded by places of interest such as restaurants, commerce and the most important banking area of the city, and its proximity to the Iglesia del Carmen metro station provides easy transportation in and out of Panama City.
Popular amenities for Panama City apartment rentals
Weekly apartment rentals

Beautiful apartment in Casco Viejo ST. George D

Cozy apartment in Panama

Oceanview 1BR in Yoo Panama

New apartment in the heart of Panama

Elegant Apt in Costa del Este. Premium Amenities

Brand new 1B 1B apartment in a vibrant area

Best Location, Beautiful Apartment, Panama

The black and white home. PH living 73 . Apto 10J
Private apartment rentals

A cozy Casco Viejo apartment

Beautifull 1BR Apt With Comfy Hotel Linens

Centrally located apartment.

1bd/2Bthrm East Coast-Panama

Elegant Apt - View to Main Plaza of Casco Viejo

On the beach. Entire floor with oceanfront terrace

Elegant apartment Av. Balboa The Sands

Modern Residential Suite in Panama City
Apartment rentals with a hot tub

Luxury Apartment in Panama | 2BR + Views + Pool

Suite Luxury 30th View , Cinta Costera Panama

PH Yoo 44i – Ocean View Apartment

New Flat with Ocean + City Views

Spacious Oceanfront Apartment

Tropical Paradise at Playa Bonita

Panama Dream View Escape

Coastal Chic Executive Studio in Panama City
Quick stats about flat rentals in Panama City

Total holiday rentals
Explore 2,890 holiday rentals in Panama City

Nightly prices starting at
Panama City holiday rentals start at $13 SGD per night before taxes and fees

Verified guest reviews
Over 79,200 verified reviews to help you choose

Family-friendly holiday rentals
900 properties offer extra space & child-friendly amenities

Pet-friendly holiday rentals
Find 1,090 rentals that welcome pets

Holiday rentals with a pool
1,840 properties feature pools

Rentals with dedicated workspaces
1,770 properties have a dedicated workspace

Wifi availability
2,760 of Panama City holiday rentals include wifi access

Popular amenities for guests
Guests love Kitchen, Wifi and Pool across Panama City rentals

4.7 Average rating
Panama City stays receive an average rating of 4.7 out of 5 from guests

Nearby attractions
Panama City’s top spots include Miraflores Locks, Museo de Arte Contemporáneo and Santo Tomas (Panama Metro)
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- Things to do Panama
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