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Apartment holiday rentals in Panama City

Find and book unique apartments on Airbnb

Top-rated apartment rentals in Panama City

Guests agree: these apartments are highly rated for location, cleanliness and more.

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Top guest favourite
Flat in Panamá
4.98 out of 5 average rating, 221 reviews

In the heart of Casco, refurbished and with parking

Escape and discover the old town in this remodeled, comfortable and central accommodation in the heart of Casco Viejo. Our location is the best, it will make you come back. Close to restaurants, bars, impressive churches, and museums. The property dates back to the 17th century (1756) history and good atmosphere. You can explore the area on foot, fully equipped kitchen, European king bed, you will feel right at home, surrounded by the famous calicanto walls. -A large living room -Fully-equiped kitchen

Top guest favourite
Flat in Obarrio
4.96 out of 5 average rating, 27 reviews

Modern apartment in the heart of Obarrio

This apartment stands out for its prime location in Obarrio, with a modern and cozy design. Located on the 14th floor, it offers a spectacular view, its decoration in neutral tones conveys serenity. The comfort of having two bathrooms makes it unique. Ideal for travelers looking for tranquility and functionality. Located within walking distance of Calle 50 and the iconic El Tornillo building. You're surrounded by casinos, hotels, and restaurants. Safe area to walk and enjoy the city.

Guest favourite
An infinity pool stretches along the edge of the property, offering panoramic views of the city skyline and waterway. Lounge chairs in bright colors are positioned around the pool area, with vast glass windows reflecting the serene landscape.
Flat in Panamá
4.83 out of 5 average rating, 181 reviews

private ocean view studio apto.

The Sand Avenida Balboa cuenta con apartamentos tipo estudio de 24 metros, amueblado y con acabados, cada apartamento cuenta con una pequeña cocina, baño privado, armario y muebles cómodos; incluyen ventanas de piso a techo. The Sand Avenida Balboa está idealmente ubicado en el corazón de la ciudad de Panamá, Avenida Balboa con fácil acceso al centro, al Casco Antiguo y a menos de 5 minutos de Causeway y el BiomuseoDisfruta de una experiencia con estilo en este alojamiento céntrico.

Top guest favourite
A stylish living area features a modern white TV unit mounted on the wall, with decorative elements and a cozy seating option. A queen bed is visible in the adjacent space, complemented by warm wooden paneling. Natural light fills the room through large windows.
Flat in Panamá
5 out of 5 average rating, 22 reviews

Remote Working • Rooftop Pool Gym • NearMultiplaza

➤ Nice apartment with balcony, nestled conveniently near Multiplaza Mall . ★ Perfect for Remote Workers, desk with chair to work, 750 MB internet speed, 100 Up. ★ Walk 5-10 mins to Restaurants, Supermarkets, Multiplaza Mall, Cafes & Entertainment. ➤ Urban Escape - Building Highlights: ★ State-of-the-art Gym ★ 2 Co-Working Spaces, 500 MB speed internet. ★ Chlorine-free Pool on the Rooftop Terrace. ➤ Located in Central San Francisco: Explore the City Easily | Uber-Friendly

Top guest favourite
Flat in Panama City
4.97 out of 5 average rating, 95 reviews

Amazing loft with an iconic view of Casco Viejo

Enjoy a unique experience, in this elegant and centrally-located loft. Fully remodeled 1 bedroom apartment, in a central location in Casco Viejo (the old city). You will be just steps away from many restaurants, cafes, museums, and the existing night life casco has to offer. Located in “Jeronimo,” this restored- colonial building was built in the year 1850, and features unique crafted wall décor, as well as some of the original "calicanto" walls.

Top guest favourite
A welcoming living area features modern furnishings and vibrant artwork. A round wooden coffee table is accompanied by a cozy sofa and armchairs. Natural light pours in from large glass doors leading to a balcony, while a plant adds a touch of greenery.
Flat in Panamá
4.95 out of 5 average rating, 132 reviews

Luxury apartment in Panama, ocean view

Located in San Francisco, one of Panama's exclusive areas par excellence, where gastronomy, history, modernity, and entertainment magically combine. Wonderful location near must-see destinations, gym, swimming pool, co-working, pet spa, and terrace. Parking is charged. Modern and functional, this apartment features a queen-size bed, fully-equipped kitchen, Wi-Fi, TV, a spectacular balcony with ocean views, laundry center, and sofa bed.

Superhost
Flat in Panamá
5 out of 5 average rating, 4 reviews

Cozy Studio in Cinta Costera with Home Vibes

✨ Live the "Cinta Costera Vibes" experience 🌴 from this modern studio apartment with a panoramic view of the Bay and the vibrant Balboa Avenue. Perfect for travelers looking for comfort, style, and a premium location. Enjoy the pool, restaurant, gym, and rooftop with the best sunset in Panama 🌅. Ideal for short or long stays — your home with home warmth and a 5⭐ touch. Save it as a favorite and live the Host Up experience!

Guest favourite
A modern dining area features a white table set for four, surrounded by stylish chairs. Large windows allow natural light to fill the space, revealing views of the city skyline. A sleek kitchen is visible in the background, showcasing a gas stove and granite countertops.
Flat in Panamá
4.94 out of 5 average rating, 110 reviews

k*| Delightful 1 BR w/King Bed in Calle 50

Calle 50 es el Times Square de la Ciudad de Panamá. Esta emblemática calle resguarda a la concurrida Area Bancaria. La ubicación del apartamento es excepcional y céntrica, cercana a: ->Estación Iglesia del Carmen [Línea 1 del Metro de Panamá] ->Cinta Costera ->Parque Urracá ->Supermercado Rey ->F&F Tower (Edificio del "Tornillo") ->Nightlife en Calle Uruguay Desde el piso 19 se ofrecen vistas a la ciudad y a la selva.

Guest favourite
Flat in Panamá
4.99 out of 5 average rating, 135 reviews

Full apartment in Panama

This charming apartment is located in one of the best neighborhoods in Panama, San Francisco, a downtown location where you will find ample cuisine, entertainment venues, close to bus stations, and the city's most important shopping mall, Multiplaza. This central and quiet apartment is an opportunity you won't want to miss. It offers the perfect combination of comfort, beauty, and a convenient location.

Guest favourite
A modern living area is illuminated by a stylish light fixture. A comfortable white sofa is paired with a round coffee table and accentuated by decorative cushions. Large glass doors provide a view of the city skyline, while a wooden accent wall adds warmth to the space.
Flat in Panamá
4.94 out of 5 average rating, 85 reviews

New Apartment in Panama City

Explore Panama City with style from our luxurious 1-bedroom apartment in San Francisco. The apartment is brand new and designed specifically for your comfort. Ideal for 2 guests, with a private bedroom, fully equipped kitchen, and a balcony with city views. Building amenities include a pool, gym, co-working center, and 24-hour security. Near shopping, dining, and Parque Omar. Book your stay today!

Superhost
A private terrace features a jacuzzi surrounded by lush greenery against an exposed stone wall. Wooden decking creates a warm ambiance, complemented by two lounge chairs designed for relaxation, offering an inviting outdoor space for guests.
Flat in Panama City
4.89 out of 5 average rating, 161 reviews

Jacuzzi in colonial ruins in beautiful apartment

Welcome to Casa Marquez Portazgo! This cozy apartment in the heart of Panama City offers comfort and convenience, ideal for your stay. With one bedroom and capacity for two people, you'll enjoy a relaxing atmosphere in 70 m². Located in the San Felipe neighborhood, just steps from the entrance to the Casco Antiguo, it offers a unique experience. You can also unwind in the jacuzzi.

Top guest favourite
A modern living space features a light-colored sofa accompanied by a round coffee table. A large television is mounted on a decorative wall behind the sofa. Natural light streams through tall windows dressed with sheer curtains, enhancing the cozy atmosphere.
Flat in Panamá
4.93 out of 5 average rating, 60 reviews

Elegant apartment with a view & the warmth of home

This apartment with the warmth of home, elegant and comfortable with spectacular views of the city, located in one of the best areas of Panama City, surrounded by places of interest such as restaurants, commerce and the most important banking area of ​​the city, and its proximity to the Iglesia del Carmen metro station provides easy transportation in and out of Panama City.

Popular amenities for Panama City apartment rentals

Quick stats about flat rentals in Panama City

  • Total holiday rentals

    Explore 2,890 holiday rentals in Panama City

  • Nightly prices starting at

    Panama City holiday rentals start at $13 SGD per night before taxes and fees

  • Verified guest reviews

    Over 79,200 verified reviews to help you choose

  • Family-friendly holiday rentals

    900 properties offer extra space & child-friendly amenities

  • Pet-friendly holiday rentals

    Find 1,090 rentals that welcome pets

  • Holiday rentals with a pool

    1,840 properties feature pools

  • Rentals with dedicated workspaces

    1,770 properties have a dedicated workspace

  • Wifi availability

    2,760 of Panama City holiday rentals include wifi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi and Pool across Panama City rentals

  • 4.7 Average rating

    Panama City stays receive an average rating of 4.7 out of 5 from guests

  • Nearby attractions

    Panama City’s top spots include Miraflores Locks, Museo de Arte Contemporáneo and Santo Tomas (Panama Metro)

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