
Apartment holiday rentals in Panama City
Find and book unique apartments on Airbnb
Quick stats about flat rentals in Panama City

Total holiday rentals
Explore 3,150 holiday rentals in Panama City

Nightly prices starting at
Panama City holiday rentals start at $13 SGD per night before taxes and fees

Verified guest reviews
Over 97,220 verified reviews to help you choose

Family-friendly holiday rentals
1,010 properties offer extra space & child-friendly amenities

Pet-friendly holiday rentals
Find 1,180 rentals that welcome pets

Holiday rentals with a pool
2,170 properties feature pools

Rentals with dedicated workspaces
2,060 properties have a dedicated workspace

Wifi availability
3,090 of Panama City holiday rentals include wifi access

Popular amenities for guests
Guests love Kitchen, Wifi and Pool across Panama City rentals

4.7 Average rating
Panama City stays receive an average rating of 4.7 out of 5 from guests

Nearby attractions
Panama City’s top spots include Miraflores Locks, Museo de Arte Contemporáneo and Santo Tomas (Panama Metro)
Top-rated apartment rentals in Panama City
Guests agree: these apartments are highly rated for location, cleanliness and more.

Panoramic Casco Viejo Lookout in The Sands
exquisite apartment blends cozy comfort with sophisticated luxury. Every detail radiates elegance, from the plush, high-end furnishings to the warm, inviting ambiance. The open-concept living area is perfect for relaxing or entertaining, with breathtaking views of the UNESCO World Heritage Casco Viejo framing the horizon. The compact kitchen has modern appliances, sleek countertops, and all essentials. With Casco Viejo vistas, this stylish retreat is perfect for exploring culture and history.
4.94 out of 5 average rating, 77 reviews
The View of Casco: Designer Loft with best Balcony
Sip your morning coffee or evening wine on the balcony, taking in a stunning, panoramic view of the city skyline! Experience the absolute best of Casco Viejo from this elegant, fully remodeled 1-bedroom loft. Nestled inside a beautifully restored 1850 colonial building—featuring historic, original calicanto walls—this stylish space puts the entire city at your doorstep. You are just steps away from world-class dining, vibrant cafes, museums, and Casco's legendary nightlife
4.98 out of 5 average rating, 134 reviews
Ocean View Apt in Panama, Yoo&Arts
Iconic luxury at Yoo&Arts Panama. This spectacular 130m² (1,400 sq ft) apartment offers sophisticated design and a breathtaking panoramic view of the Pacific Ocean. Enjoy breakfast on the balcony with an exceptional breeze, watch the sunrise from your bedroom, or work in an inspiring environment. Located on Avenida Balboa, the city's most exclusive area, you’ll have direct access to fine dining inside the building, premium supermarkets, and shopping malls nearby.
4.8 out of 5 average rating, 145 reviews
k*| Breathtaking Oceanview 1BR in Ave Balboa
Experience luxury in this oceanfront 1-bedroom apartment on Balboa Avenue with stunning views of the Pacific Ocean, Casco Viejo, and modern Panama City. Fully equipped for long stays with A/C, Water, TV, cable, and WiFi. Located in a unique building with amenities like Poin, a zipline between buildings, plus restaurants like Cielo, Osaka, and Patria. Walk to Cinta Costera and a subway station. Everything you need is right here—your perfect Panama getaway!
4.83 out of 5 average rating, 115 reviews
Luxury apt in Panama City 2 Rooms 3 Baths
The Wanders by yoo building is located in the heart of the city. It is an extraordinary project where every corner has a story to tell. 24/7 reception, many recreation areas, hydration station. Outside the lobby, there is the Cafetería cafe con teclas and a Popino Carnes restaurant. In the social area, bar service in the pools, children's park, games room with screens on the ceiling bathrooms, function room, kitchen for events, fully equipped gym and more
5.0 out of 5 average rating, 88 reviews
The apartment of a legendary Panamanian footballer
Location is everything – just steps away from the city’s best restaurants, bars, stunning churches, and fascinating museums. Explore the historic district on foot while enjoying the comfort of a stylish apartment featuring: • A spectacular balcony with beautiful views • A fully equipped kitchen • 1.5 bathrooms • Cozy beds that make you feel right at home • Surrounded by iconic calicanto stone walls that reflect the charm of Panama’s colonial past.
4.99 out of 5 average rating, 208 reviews
Ocean View | Rooftop Pool | Luxury Stay
Wake up to a stunning ocean view right from your window at BrisaMarina. This luxury apartment is located in the spectacular The Sands building, right on the Cinta Costera. The modern and cozy space features bright natural light, air conditioning, high-speed Wi-Fi, and a fully equipped kitchen for your comfort. You’ll be just minutes away from restaurants, beaches, and top attractions. Perfect for couples, business travelers, or weekend getaways.
4.97 out of 5 average rating, 97 reviews
Luxury apartment in downtown Panama, banking area
We have a strategic location right on the main road of Panama (Calle 50) Bella Vista. You will find yourself located in the heart of the banking area. Whether you're coming for work or vacation, this is the ideal place. You'll find all kinds of restaurants, shops, and shopping malls nearby. You'll have the Cinta Costera just a 10-minute walk away where you can walk or exercise. Fun and enjoyment within walking distance
4.92 out of 5 average rating, 178 reviews
Beautiful Apt, Best Location 2BR
Beautiful apartment, high floor up, with 2 bedrooms, 2 bathrooms, walking closet, and essential closet for the second bedroom. Extra twin bed available in the apartment. High speed internet, 300Mbps by Wifi aprox. , 600Mbps by cable. Social area on the roof with swimming pool, gym, sauna and bbq area. The building location is excellent, We are walking distance for grocery stores, restaurants, bank, Hilton Hotel&Casino.
4.89 out of 5 average rating, 196 reviews
Full apartment in Panama
This charming apartment is located in one of the best neighborhoods in Panama, San Francisco, a downtown location where you will find ample cuisine, entertainment venues, close to bus stations, and the city's most important shopping mall, Multiplaza. This central and quiet apartment is an opportunity you won't want to miss. It offers the perfect combination of comfort, beauty, and a convenient location.
4.97 out of 5 average rating, 166 reviews
Modern, central and comfortable (001)
Modern and cozy studio in the heart of Panama. Perfect for exploring the Old Town, the Coastal Strip and more. Full kitchen, full bed, double sofa bed, air conditioning, fast WiFi and private bathroom. Ideal for 1–4 people. Private access, elevator and self check-in. Surrounded by restaurants, transportation, and tourist sites. Your ideal base to explore the city!
4.87 out of 5 average rating, 148 reviews
PH The Gray | Balcony Views · Pool · Gym
Wake up to panoramic views of Cerro Ancón from your private balcony — right in the heart of Calle 50, Panama’s financial and lifestyle hub. The Gray is a brand-new building offering resort-style amenities: rooftop pool, gym, and a fully equipped coworking space with high-speed Wi-Fi. You’ll also find restaurants and cafés inside the building itself.
4.84 out of 5 average rating, 100 reviewsPopular amenities for Panama City apartment rentals
Weekly apartment rentals

Hotel-Style Room at The Hub, San Francisco
5.0 out of 5 average rating, 8 reviews
Luxury Stay & Panoramic Bay View in YOO Panama
4.82 out of 5 average rating, 11 reviews
Luxury Centric 2BR Apartment in Casco Viejo
4.97 out of 5 average rating, 38 reviews
Luxury Apartment in Obarrio Rooftop & Pool
5.0 out of 5 average rating, 4 reviews
Luxury apartment in the heart of Panama
4.92 out of 5 average rating, 36 reviews
Unique Luxury 3-story Loft at the Yoo
4.96 out of 5 average rating, 89 reviews
Historic Casa Donovan | Old Town & City Views
4.75 out of 5 average rating, 4 reviews
Live the Wanders And Yoo Experience in Panama
4.98 out of 5 average rating, 44 reviewsPrivate apartment rentals

Most Beautiful Loft in the Heart of Casco Viejo
5.0 out of 5 average rating, 36 reviews
Modern City Escape Nice Views & Great Location!
5.0 out of 5 average rating, 36 reviews
Tropicool Casco Loft w/King Bed & Rooftop
4.99 out of 5 average rating, 77 reviews
“Modernity and Comfort in the City”
4.97 out of 5 average rating, 86 reviews
5B • 5 Bedroom Apt • 4 Baths • Ideal for 10 Guests
4.96 out of 5 average rating, 24 reviews
Apartment in Panama City
4.89 out of 5 average rating, 89 reviews
New apartment in the heart of Panama
4.94 out of 5 average rating, 51 reviews
Luxury Oceanfront Resort 22nd Floor View, 200°
4.85 out of 5 average rating, 73 reviewsApartment rentals with a hot tub

New Flat with Ocean + City Views
4.78 out of 5 average rating, 125 reviews
Tropical Paradise at Playa Bonita
4.93 out of 5 average rating, 118 reviews
Luxury 2BR Suite with Pool & Views
5.0 out of 5 average rating, 45 reviews
Luxurious apartment in Marbella
4.9 out of 5 average rating, 51 reviews
PH Yoo 44i – Ocean View Apartment
4.85 out of 5 average rating, 85 reviews
Ocean View | 2 King Beds | Prime Loc | 600mbs WiFi
5.0 out of 5 average rating, 16 reviews
Ocean View | Infinity pool | Balbia Ave Apt
4.93 out of 5 average rating, 59 reviews
Premium APT | Downtown | Design, Comfort, Parking
5.0 out of 5 average rating, 6 reviewsDestinations to explore
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