
Apartment holiday rentals in Panama City
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Top-rated apartment rentals in Panama City
Guests agree: these apartments are highly rated for location, cleanliness and more.

Best Location – Fancy Apartment in Casco Viejo
Experience absolute luxury in our fully remodeled loft, with access to a spectacular 360° rooftop terrace, where you'll enjoy breathtaking views of the city and skyline. The building also features an elevator for your convenience. Located right in front of a vibrant plaza with renowned restaurants, the location is truly unbeatable, and security in the area is excellent. Relax in the rooftop, enjoy sunset views from the terrace, and experience the unique charm of Panama’s historic Casco Antiguo

Apartment Av. Balboa, Yoo&Arts
Accommodation with the best ocean view in Panama, Yoo & Arts Building, 130 meters. You can enjoy various environments during your stay, have breakfast on our balcony with an exceptional ocean view, watch the sunrise from your bedroom, or even work in an excellent environment. You can have easy access to haute cuisine restaurants in the same building as the accommodation, supermarkets nearby, shopping malls. Luxury will be all around you as the building is one of the most exclusive in the area.

Apto 4 min from Tocumen Airport | 24-hr check-in
Layover in Panama? Stay where everything is easy and comfortable Just 4 minutes from Tocumen International Airport – perfect for early flights or quick stopovers A modern, comfortable, and secure apartment with: • Fast WiFi and air conditioning • Smart lock and flexible check-in • 24/7 security • Pool, gym, and fully equipped kitchen • Steps from the ITSE Metro station Ideal for layover travelers, curious tourists, or business trips. 🌴 Just arrive — everything’s ready for you. We’ll be waiting!

Apartment with unique views to remember
Pasarás una Experiencia con estilo, alojamiento céntrico. acceso a líneas de buses y el Metro, restaurante , grocery store 24 horas, y una vida nocturna genial, casinos, cinta costera, iglesia del Carmen. casco antiguo a minutos en uber. compras. Soho Mall, Multi Plaza Mall y Albrook Mall. Piscina para adultos y niños. Bar, restaurante, rooftop vistas panorámicas, coworking, gym. Una habitación Con cama queen y un sofá cama en la sala para huéspedes extras (costo xtra 15.00 pp x noche)

Casco Viejo 360° View Old Tower Penthouse
Located in one of the oldest buildings in Panama and set over 3 stories with unrivaled panoramic views over the historical Casco Viejo, the skyline of Panama City and views of the causeway, our gorgeous penthouse is the ideal space to take in the local sights, sounds, art, culture, socialize with your friends and family, or simply relax in a cozy love nest! Top speed wifi, excellent location, and fully equipped with all the home comforts, the penthouse is the perfect spot to explore Panama.

Luxury Mid-Century Apartment In Casco Viejo
Luxury mid-century one bedroom Boutiqe 72 m2 apartment. Step into the elegant, functional and comfortable place that we offer with love. The apartment located within a beautiful two-floors antique building in the heart of Casco Viejo. The apartment includes a well equipped brand new kitchen, a dining area and a spacious living room, also a balcony with a view of the lively streets below. The tranquil bedroom has an ensuite bathroom and a walking closet that fitting perfectly to your needs.

The View of Casco: Designer Loft with best Balcony
Sip your morning coffee or evening wine on the balcony, taking in a stunning, panoramic view of the city skyline! Experience the absolute best of Casco Viejo from this elegant, fully remodeled 1-bedroom loft. Nestled inside a beautifully restored 1850 colonial building—featuring historic, original calicanto walls—this stylish space puts the entire city at your doorstep. You are just steps away from world-class dining, vibrant cafes, museums, and Casco's legendary nightlife

The apartment of a legendary Panamanian footballer
Location is everything – just steps away from the city’s best restaurants, bars, stunning churches, and fascinating museums. Explore the historic district on foot while enjoying the comfort of a stylish apartment featuring: • A spectacular balcony with beautiful views • A fully equipped kitchen • 1.5 bathrooms • Cozy beds that make you feel right at home • Surrounded by iconic calicanto stone walls that reflect the charm of Panama’s colonial past.

Impressive ocean and Panama City views
Enjoy a unique experience, a modern apartment with its own style, where every sunrise and sunset becomes a show. Enjoy breathtaking views of Panama City, the bay, and the Old Town from the comfort of your home. Unbeatable Location Located just 5 minutes from the charming Casco Viejo and the famous seafood market, and 10 minutes from the banking area. In addition, you will have a metro station and several bus stops just a few steps from the building

Studio apartment in the heart of Casco
Welcome to Casa Pérez, your retreat in the heart of the Old Town! Enjoy a prime location and the best views from a spectacular private balcony facing the most iconic square in the Casco. Ideal for 3 people, this cozy and bright one-bedroom apartment includes Wi-Fi, air conditioning, living room, dining room, equipped kitchen, washing machine and elevator for your comfort. Enjoy an unforgettable stay in a warm and fully equipped atmosphere.

k*| Delightful 1 BR w/King Bed in Calle 50
Calle 50 es el Times Square de la Ciudad de Panamá. Esta emblemática calle resguarda a la concurrida Area Bancaria. La ubicación del apartamento es excepcional y céntrica, cercana a: ->Estación Iglesia del Carmen [Línea 1 del Metro de Panamá] ->Cinta Costera ->Parque Urracá ->Supermercado Rey ->F&F Tower (Edificio del "Tornillo") ->Nightlife en Calle Uruguay Desde el piso 19 se ofrecen vistas a la ciudad y a la selva.

The best view of the Old Town
Welcome to this charming accommodation in the heart of the Casco Viejo, located on the third floor facing one of Panama's most iconic squares, Plaza Catedral! Thanks to its prime location, you will enjoy a unique view of the square and the imposing Cathedral Church. Right in this lively square, you will have a wide variety of restaurants and shops at your disposal where you can buy souvenirs of this wonderful trip.
Popular amenities for Panama City apartment rentals
Weekly apartment rentals

Luxury Centric 2BR Apartment in Casco Viejo

Private parking & rooftop | Studio Casco Center

Luxury apt in Panama City 2 Rooms 3 Baths

Luxury Balcony Stays + Pool Casco Viejo

Tropicool Casco Loft w/King Bed & Rooftop

Cozy Apartment in the Heart of Casco Viejo

Panoramic Casco Viejo Lookout in The Sands

Gorgeous Flat in the best location in Casco Viejo
Private apartment rentals

Lovely & Cozy central apartment in Casco Viejo

Comfortable oceanfront apartment

Centric - 2BDR Apt - Old Town

2BR King Suite Ocean View, Casco, Canal 500MB WIFI

Casco View: Comfortable and modern apartment in Panama

Luxury oceanfront apartment on the waterfront promenade

Spectacular Bay View • 1BR • Pool/Gym and +

"Arrive as guests. Leave feeling at home".
Apartment rentals with a hot tub

Suite Luxury 30th View Yoo Panamá & Arts Tower

Historic 2BR Loft at Casa del Horno, Old Town

Luxury 2BR Suite with Pool & Views

New Flat with Ocean + City Views

Tropical Paradise at Playa Bonita

Live the Wanders And Yoo Experience in Panama

Apartment with the warmth of home and ocean view

Oceanview Apt Near Panama City w/ King Bed & More
Quick stats about flat rentals in Panama City

Total holiday rentals
Explore 2,860 holiday rentals in Panama City

Nightly prices starting at
Panama City holiday rentals start at $13 SGD per night before taxes and fees

Verified guest reviews
Over 88,500 verified reviews to help you choose

Family-friendly holiday rentals
920 properties offer extra space & child-friendly amenities

Pet-friendly holiday rentals
Find 1,130 rentals that welcome pets

Holiday rentals with a pool
1,940 properties feature pools

Rentals with dedicated workspaces
1,910 properties have a dedicated workspace

Wifi availability
2,790 of Panama City holiday rentals include wifi access

Popular amenities for guests
Guests love Kitchen, Wifi and Pool across Panama City rentals

4.7 Average rating
Panama City stays receive an average rating of 4.7 out of 5 from guests

Nearby attractions
Panama City’s top spots include Miraflores Locks, Museo de Arte Contemporáneo and Santo Tomas (Panama Metro)
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