
House holiday rentals in Panama City
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Top-rated house rentals in Panama City
Guests agree: these houses are highly rated for location, cleanliness and more.

3BR Home in Ancon Hill - Urban Oasis
Discover our home at Ancon Hill in Panama City, steps from Supreme Court. The hill offers scenic hiking trails to the top with city views, lush greenery, and wildlife. 5 min to Albrook Mall. 10 min to Casco Viejo (UNESCO site, restaurants, museums, nightlife), Amador Causeway, Cinta Costera, Metropolitan Park, Panama Convention Center, and Albrook Airport. 20 min to Panama Canal Miraflores Locks and Veracruz beach (across Bridge of Americas, gateway to countryside). 35 min to Tocumen Airport.

Mountain Retreat
Relax and unwind at this peaceful property nestled on two hectares of lush tropical vegetation surrounded by the sights & sounds of nature. Located at Panama's Blue Mountain(Cerro Azul), 30 kilometres from Panama City. This cozy & comfortable home is equipped with modern amenities & chic decorative touches. It consists of a main house with 2 bedrooms & a 2 bedroom cottage. It has a spacious terrace, pool & jacuzzi overlooking Panama City. The property also boasts its own spring water well

Family-Friendly Panama Canal Home with Fenced Yard
Welcome to our 3-bedroom vacation rental in Cardenas, Panama Canal area! Perfect for families, this home boasts a kitchen with quality appliances, including a 6-burner gas stove and a large fridge. Relax in stylish bedrooms, featuring a king suite with a private bath, and enjoy the lush surroundings filled with wildlife. Located next to a park with sports courts, this kid-friendly neighborhood offers outdoor fun. Experience the unique blend of comfort and nature right at your doorstep!

Large Private Residence in an Excellent Area
House in the best area of the country. Very quiet street, central, close to restaurants, pharmacies, mall among others. Large comfortable residence for groups or families. Private parking for up to 2 cars 4 spacious bedrooms, 2 comfortable studios, living room, breakfast room, large terrace. *Kosher Option Available* House in one of the best areas of the country. Very quiet street, central, close to restaurants, pharmacies, mall, and more. Large, comfortable residence for groups.

Wonderful nature
Enjoy a family retreat in the heart of nature, where tranquility envelops you. This cozy accommodation, surrounded by a beautiful garden in the Metropolitan Natural Park, offers you a unique escape just 3 minutes from Albrook Mall and 5 minutes from downtown. Wake up to birdsong and a visit from the ñeques (agoutis), while relaxing in an exclusive and lively atmosphere. The perfect getaway to disconnect and enjoy nature with all the amenities!

Spacious Panama House in the 'heart of the city'
You couldn't ask for a better place to stay while you visit Panama. This location is perfect, while other properties might advertise similar amenities; not one of them can boast a combination of space and amazing location quite like this one. This is very private & secure property in a fantastic, & very safe area right in the heart of the city & close to everything! An oasis in the middle of the city with AC IN EVERY ROOM AND DININING ROOM.

Hello Panama! Brisas del Golf
Stay with HOLA PANAMA! Wonderful space, 15 minutes from Tocumen International Airport, in one of the most exquisite places in the capital of Panama, Brisas del Golf, quiet and pleasant, surrounded by shops, restaurants and the magnificent Metro mall with establishments for all your shopping. This accommodation offers you a spacious and relaxed concept for your dream vacation or business trip. You are more than welcome to Hola Panama.

Comfortable and luxurious apartment
Enjoy a stylish experience in our accommodation in the Old Town, take advantage of the location close to art galleries, restaurants, crafts, etc. Our house has three bedrooms each with a balcony, bathroom and closet, with a nice contemporary equipped kitchen; a large living and dining room, work area. You have a total area of 326 m² The whole house is surrounded by balconies where you can enjoy panoramic views.

Exceptional three-story building with sea view
This stunning three-story property, located in Casco Viejo, boasts a terrace with a sea view. Designed with a focus on elegance and relaxation, the house features spacious and well-lit interiors adorned with modern and high-quality decor. The strategic location of the house allows for breathtaking views from the terrace, offering a unique blend of luxury and relaxation in a historic and picturesque setting.

Private Studio 10 Min from the Airport!
Entire apartment 10 minutes from the airport! The apartment is fully furnished including appliances and kitchen items, toiletries, dining room, work table and more. Just a few minutes walk from the SAN ANTONIO METRO Station, restaurants, shopping malls, laundries, supermarkets and pharmacies. We offer tours to San Blas to make the most of your trip. Our house is your house in Panama 🇵🇦

Golden Space | Design By Paradox
PRIVATE APARTMENT IN PANAMA CITY, CLOSE TO CASCO VIEJO. If you're looking to get submerged into real Panama and live among the real locals. This is the right place to be. For More Info or visual content, follow us on IG as Paradox Experience and visit our Virtual Showcase with the link in our IG BIO. More than a regular stay, we are an experience.

Private Colonial Casco | 3 Suites + 2 Parkings
Restored colonial house (2024) 3 bedrooms with private bathrooms + 3.5 baths 2 private parking spaces (extremely rare in Casco) Patio/terrace with BBQ + private bar Steps from plazas, restaurants and rooftops Ideal for families and groups up to 8 guests
Popular amenities for house rentals in Panama City
House rentals with a pool

Beautiful house in Brisas del Golf

Villa Helena 3 Bedrooms Los Altos de Cerro Azul

House with Private Pool and two parking spaces

House of the waterfalls

Great Studio

On the beach, entire apartment, panoramic terrace and more

Your country house, Menus de la Montaña, awaits you.

Carmen's House
Weekly house rentals

Country house in Altos de Cerro Azul

House near the airport

Casco Viejo 02, Luxury Condo, Panama Bay.

LovelyviewPty House 15 minutes away from the airport

Residence in Panama

Altos de Cerro Azul Mountain House

The Bird's Nest - Cerro Azul

Welcome to Zola Sierra! Your Escape Into Nature.
Private house rentals

House conveniently located near the airport

Loft de diseño con terraza privada

2 bedroom apartment in the heart of Panama

Modern and minimalist Altos de Cerro Azul

Your Little House in Linda Vista

Casa Amarilla

2 bedroom house, 2 bathrooms, kitchen, dining room, in Ancon

Cozy House, Beautiful Garden, Altos de Cerro Azul
Quick stats about house rentals in Panama City

Total holiday rentals
Explore 470 holiday rentals in Panama City

Verified guest reviews
Over 7,710 verified reviews to help you choose

Family-friendly holiday rentals
180 properties offer extra space & child-friendly amenities

Pet-friendly holiday rentals
Find 160 rentals that welcome pets

Holiday rentals with a pool
90 properties feature pools

Rentals with dedicated workspaces
230 properties have a dedicated workspace

Wifi availability
430 of Panama City holiday rentals include wifi access

Popular amenities for guests
Guests love Kitchen, Wifi and Pool across Panama City rentals

4.7 Average rating
Panama City stays receive an average rating of 4.7 out of 5 from guests

Nearby attractions
Panama City’s top spots include Miraflores Locks, Museo de Arte Contemporáneo and Santo Tomas (Panama Metro)
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