
Guest house holiday rentals in Panama City
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Top-rated guest house rentals in Panama City
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Unique find: central+urban+ huge green yard+safe
Wake up to the sound of birds in this hidden retreat in the heart of the trendy & safe "El Cangrejo" neighborhood. Housed on the ground-floor of a 2-story building built in the 50's. Features a HUGE private green yard, perfect for relaxing or spotting hummingbirds with an outdoor dining set. Steps from cafés, galleries, parks, metro, nightlife & restaurants. Free Private parking & Fast WiFi. Thoughtfully decorated to help you feel at home. The space not suitable for children under 12.

Efficiency Bungalow - Metropolitan Natural Park
Casita Curundu is located in a quiet and beautiful neighborhood next to the Metropolitan Natural Park. A naturalist delight right in the city, surrounded by an urban jungle forest teeming with birds and wildlife. An amazing place for a couple to stay - you’ll have all the privacy you need but still be close to all the great attractions and the large shopping and transportation hub Albrook Mall, Airport, Bus & Metro Station and yet removed from the hustle and bustle of the city.

La mexicana
La Mexicana en Altos de Cerro Azul 🏔️🌵 Escapada rústica de 2 pisos para 16+ personas. 5 habs, 4 baños, cocina equipada, Wi-Fi y TV. ¡Pet friendly! 🐾 Disfruta del jardín extenso, terraza con hamacas, asador y mesa de dominó. Noches de fogata en la chimenea interior y días de aventura en ríos y senderos cercanos. El auténtico "vibe" mexicano en el frescor de la montaña. Ideal para grupos grandes que buscan desconectarse con total comodidad. ¡Reserva tu trip!

Garden Cottage in Panama City
Welcome to our charming cottage, an oasis in the heart of the city, ideal for nature lovers and comfort seekers. Located in a central area, this retreat offers the perfect combination of tranquility, comfort, and proximity to Panama's main attractions. Enjoy the balance between urban life and the serenity of the natural surroundings. It features a private entrance, a spacious garden, a barbecue area, and a terrace where you can relax and connect with nature.

Smart Stay by SS • Budget Studio 5+ Airport & Mall
Affordable studio just 11minutes from Tocumen Airport and very close to the Panapark Free Zone, making it ideal for both business and transit travelers. The space offers Wi-Fi, a TV with Netflix, and is surrounded by supermarkets and stores. It’s a simple, private, and comfortable place to rest. ✅Perfect for engineers and business travelers looking for a good, nice, and affordable place. ✔ Fast Internet ✔ Self check-in ✔ Modern and secure spaces ✔ A/C

Convenient, centrally located suite with parking
This special place is close to everything, making it easy to plan your visit. 5-10 minutes to any attraction in Panama City. Assigned parking and two blocks from major bus stop that can take you anywhere in the city or accross the country. You will have the entire place for yourself with independent entry, air conditioning and kitchen. There are four grocery stores walking distance. You can exercise daily at a park located behind the property.

Cool Guesthouse + WiFi + Pool + TV + AC @ Panama Canal
✔️Verified Superhost! Your stay will be in the best hands Guest house, Near the City of Knowledge 🇵🇦 📍 In the tropical forest of the old Clayton base, with amenities, parks, sports and gastronomy. Close to the city, shopping malls, the Miraflores Locks and the transoceanic railway🇵🇦 We offer: 💧 Hot Water 📶 Wifi ❄️ AC 🏊♂️ Pool 📺 Smart TV and Cable 🚗Parking This strategic location, with a high level of security in the area.

Ancon Garden Studio - Panama City | Fast WiFi
Nestled in the former Canal Zone, this cozy studio is ideal for remote work and easy city access. Enjoy fast WiFi, a calm green setting, and quick connections to Cerro Ancón, the Panama Canal Railway Station, Los Ríos Pool, and City of Knowledge. Minutes from downtown and Albrook Metro. Perfect for digital nomads, solo travelers, or couples seeking a peaceful, well-connected base. It includes a desk and a comfortable chair for working. 🌈

Apartment in a safe residential area
You'll be close to everything when you stay at this centrally located accommodation. About 20 minutes from Tocumen Airport, 15 minutes from Romel Stadium, passing through Colon Free Zone near shops, restaurants, pharmacies, supermarkets, cinemas, easy transportation. Whether the trip is for work, as a tourist, or in transit through Panama, you can be comfortable in this apartment. We are available if you need additional information.

For 4 people 2 separate rooms in park
Quiet sleep surrounded by lush greenery 20 minutes from Panama spacious accommodation suitable for 2 couples or family of 4 people 1 queen bed and 2 twins with each en-suite private bathroom, provision of an umbrella bed Rest room hammock , equipped kitchen dining room, a saltwater pool to entertain you facing the ocean whose only users you are surrounded by a large garden Workspace with fast wifi Water sports, hiking nearby

Private guest house in Ancón
Enjoy the simplicity of this cozy, quiet, and centrally-located accommodation. Close to places of interest such as the Panama Canal Administration building, Amador Causeway, Albrook Mall, and several restaurants. Personally decorated to provide comfort... large windows in the bedroom provide natural lighting and a view of the garden and green area through the windows; yet it maintains the desired privacy and tranquility.

Boho Studio - Private Terrace 9 km from the airport
Perfecto para 1–2 huéspedes, Wifi, Terraza tranquila, cuarto independiente, cuenta con A/C , y su baño pequeño. Ubicado cerca del Aeropuerto Internacional de Tocumen, de 10 a 13 minutos en auto. El Studio está Cerca de 2 Centros Comerciales, Metromall y Los Pueblos OUTLET. La zona residencial es segura al caminar, calles organizadas y limpias. Tenemos la estación del Metro de Cerro Viento afuera en Metromall.
Popular amenities for guest house rentals in Panama City
Family-friendly guest house rentals

Casa Relic - Room #4 Mixed Dormitory

CY7 l Habitacion privada con terraza

CY4 l Habitacion privada en Marbella

CY5 l Habitacion privada en Marbella

Private Ensuite Room

CY8 l Habitacion privada en Marbella

Private Room in Smart Hostel

CY3 l Habitacion privada en Marbella
Guest house rentals with a patio

CY1 l Habitacion c/entrada privada en Marbella

Bedroom#6+kitchen+WiFi+A/C+Close to the subway

Room+Parking+TV+Kitchen+Work Area+WiFi@PanamáCity

Accommodation near Tocumen Airport

Dormitorio 15 minutos del aeropuerto tranquilo

Comfortable room in the City

Female Dorm in Smart Hostel

Private suite
Guest house rentals with a washing machine and dryer

Jacuzzi | Sauna | BBQ | Senderismo

Refugio en las Montañas | Calm & Romance

Airport Studio 1 by SS-affordable stay 5 min AIRPT

Airport Studio 2 by SS -affordable stay 5 min ARPT

Private Ocean-View Room in Premium Balboa Building

WHERE YOYI

Smart Stay by SS • Budget Studio 3+ Airport & Mall

Room, nature, sauna and eveything, near the sea.
Quick stats about guest house rentals in Panama City

Total holiday rentals
Explore 90 holiday rentals in Panama City

Nightly prices starting at
Panama City holiday rentals start at $13 SGD per night before taxes and fees

Verified guest reviews
Over 1,890 verified reviews to help you choose

Family-friendly holiday rentals
10 properties offer extra space & child-friendly amenities

Pet-friendly holiday rentals
Find 20 rentals that welcome pets

Holiday rentals with a pool
10 properties feature pools

Rentals with dedicated workspaces
30 properties have a dedicated workspace

Wifi availability
80 of Panama City holiday rentals include wifi access

Popular amenities for guests
Guests love Kitchen, Wifi and Pool across Panama City rentals

Nearby attractions
Panama City’s top spots include Miraflores Locks, Museo de Arte Contemporáneo and Santo Tomas (Panama Metro)
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