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Apartment holiday rentals in Panama City

Find and book unique apartments on Airbnb

Top-rated apartment rentals in Panama City

Guests agree: these apartments are highly rated for location, cleanliness and more.

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Guest favourite
An indoor garden is showcased, featuring lush greenery and soft lighting. A glass roof allows natural light to illuminate the space, which is accented by warm-toned stone walls. Two stylish chairs are positioned nearby, creating a comfortable seating area.
Apartment in Panamá
4.91 out of 5 average rating, 119 reviews

CASA SAEMA -PRESTIGIOUS DUPLEX PENTHOUSE WITH TERRACES

Spectacular duplex penthouse in Panama's old town, 265 square meters with balconies, private outdoor terraces, it has an interior garden lounge, a dining room, 3 bedrooms (+ sofa bed in studio), recently renovated with a loft concept, unique and comfortable exclusive design, in the best area of the old town, perfect for relaxing and unwinding, kitchen, dishwasher, living room with washing machine, swimming pool, elevator, 24-7 doorman, children who cannot swim are not allowed, a wide variety of leisure activities in the area.

Top guest favourite
A modern living space features a sleek gray sofa and a circular coffee table, with a view of the city visible through large floor-to-ceiling windows. Two yellow chairs add a pop of color, enhancing the bright and airy atmosphere.
Apartment in Panamá
5 out of 5 average rating, 32 reviews

New Modern Condo 1BR Best Location! Rooftop Pool

➤ Centrally located in San Francisco, one of the best neighborhoods in Panamá City. Enjoy the high floor view from your private Balcony! FREE EARLY CHECK-IN (subject to availability) ★ Close to everything! Walk 5-10 mins to the Best Restaurants, Supermarkets and Multiplaza: the best Mall in Panamá Travel with the comfort of being in your home! in this new, high floor, modern and minimalist full apartment with top of the line appliances, which is great for personal/business or family enjoyment

Top guest favourite
An open-concept living area features modern furnishings with a comfortable grey sofa and decor accents. A dining table for two is situated nearby, next to a well-equipped kitchen. Large windows allow natural light to brighten the space and provide city views, emphasizing a vibrant atmosphere.
Apartment in Panamá
4.98 out of 5 average rating, 64 reviews

A Modern & Cozy Apartment In Prime Location

The unit apartment is spacious with balcony & great views. It’s located in safe & prime location. Walking distance to metro station, Cinta Costera park, Panama Bay, restaurants, entertainments, bars. Location is known for being a vibrant area with a mix of upscale & local options. The unit offers Free High Speed Wi-Fi & Cable Smart TVs. The common areas have free Swimming Pool, Gym, Office Workspace with Wi-Fi & Parking. The building features a Restaurant, Rooftop Bar, Coffee Shop & Nail Salons

Top guest favourite
A cozy bedroom is featured, showcasing a spacious bed adorned with decorative pillows and a soft throw. Large windows offer a view of the city skyline, while modern artwork adds a touch of color to the walls. A wardrobe is positioned against one side.
Apartment in Panama City
4.91 out of 5 average rating, 116 reviews

Central, comfortable studio with bay view

Enjoy a stay in the Center of Panama City! Small, equipped and comfortable studio on Av. Centro de España with 42nd Street in Bella Vista, ideal for one or two travelers. Steps from the Santo Tomás Metro station. A 5-minute walk from the Cinta Costera going down, Parque Urracá, Supermarket Rey and Riba Smith, Zona Bancaria (Calle 50), Calle Uruguay (restaurant area), 15 minutes by car from the Old Town and more. Enjoy the different amenities we offer you!

Guest favourite
A spacious bedroom is shown, featuring a large bed with white bedding against a soft blue wall. Two orange chairs are positioned by the window, which offers an expansive view. A bedside lamp and a small nightstand complement the modern furnishings.
Apartment in Panamá
4.89 out of 5 average rating, 9 reviews

YOO View | Chic Suite facing the Coastal Belt

This 1Hb apartment offers you an exceptional experience. Discover it. Its ocean-view balcony is ideal for gazing at the sea and the city from above. King bed, walking closet and a private bathroom with vanity, double sink, fully equipped open kitchen, perfect for those who love to cook, share a wine or work. Includes dishwasher, private laundry area and a guest bathroom. If you're looking for luxury, comfort, and a prime location, this is the place.

Guest favourite
A spacious living area features a light gray sectional sofa and a dark coffee table, surrounded by a patterned area rug. A television is placed on a low console, while a dining area with dark chairs and a table is visible in the background.
Apartment in Panamá
4.96 out of 5 average rating, 104 reviews

Cozy 2 bedroom Apt. in Panama City, Panama

Best lodging option, conveniently, located in the center of bustling Panama City. You’ll be staying in a spacious, cozy, fully equipped apartment, with fast internet access, cable TV, including all the popular streaming services. Near great dinning options, coffee shops, nightlife spots, city parks, high end shopping centers, and city transport to take you to all the popular tourist spots that Panama City has to offer. It’s a home away from home.

Superhost
A modern living area features a comfortable, light grey sofa accompanied by two accent pillows. A round coffee table sits in front, and large windows provide a view of the city skyline. Natural light brightens the space, creating an open and airy environment.
Apartment in Marbella
4.86 out of 5 average rating, 104 reviews

Ph Quartier Marbella 18E apt with rooftop pool

Excellent apartment in the center of the city, high floor with excellent view, full kitchen, premium furniture, large balcony, room with hotel quality sheets, 4 minutes walk from the coastal strip av balboa, surrounded by restaurants and shops, safe area for walk. Excelente apartamento en el centro de la ciudad, piso alto con excelente vista, cocina completa, muebles premium, amplio balcón, a 4 minutos caminando de la cinta costera av balboa.

Top guest favourite
A modern living area features a soft beige sofa facing a flat-screen TV mounted on a textured stone wall. Large glass doors provide a view of vibrant city buildings and the coastline, allowing natural light to illuminate the space.
Apartment in Panamá
5 out of 5 average rating, 25 reviews

180° Casco Viejo Views, Pool & Coworking

☆ What our guests are saying: "The view was astonishing." "It is clean, quaint, and cozy." "I truly felt safe, and it was very modern." "No one can beat this treatment Chef kiss". ☆ Early check-in is available! AMENITIES: ☆ Salt-water pool. ☆ Comfy coworking space with free wifi. ☆ High-speed elevators. ☆ Bicycle rental is available in the lobby. ☆ Parking space (extra fee applies). ☆ Lobby concierge and 24/7 security.

Guest favourite
A well-lit bedroom features a spacious bed with light-colored bedding, complemented by decorative wall art. Natural light enters through large glass doors, which open to a small terrace with greenery. A cozy armchair is positioned nearby, enhancing the room's inviting atmosphere.
Apartment in Panamá
5 out of 5 average rating, 14 reviews

King Bed, Creative Design Steps from Casco Viejo

Casco 114 is a stay created by travelers, for travelers. Located in the heart of Santa Ana, the creative district of Panama’s Casco viejo, it offers a king bed, full-size trundle, sofa bed, private terrace, washer/dryer, and unique decor. At PH Casco View: enjoy a saltwater pool, coworking space, stunning views of both the Old Town and the modern city, paid parking, and all the comforts for an unforgettable stay.

Top guest favourite
Apartment in Panama
4.99 out of 5 average rating, 257 reviews

Patty’s Cozy Studio with K bed in Casco Viejo

Best location by the “El Rey" Supermarket...Casco's only grocery store! Prime location steps away from restaurants, bars, cafes, plazas and great little breakfast places with the lovely water front promenade around the corner making it the perfect “pied-à-terre!” The studio has a fully stocked kitchen aside from the main living space. It is spacious, comfortable and tastefully decorated!

Superhost
A swimming pool is situated on a rooftop terrace, surrounded by a green hedge and featuring clear blue water. Tall buildings and a bright sky are visible in the background, creating an urban atmosphere. A small buoy floats in the water, adding a touch of color.
Apartment in Panamá
4.92 out of 5 average rating, 24 reviews

Brand new condo, Calle 50

The apartment is new and ready to move in, just steps away you will find restaurants, bars, shopping centers due to its excellent location in the financial area. The metro station is a 5-minute walk away, WI FI 150 Mbps, NETFLIX, PRIME VIDEO, high floor, elevator, air conditioning, swimming pool, parking, laundry center, water heater, kitchen, excellent view and location.... ....

Guest favourite
A dining area is featured with a wooden table and four black chairs, complemented by woven placemats. A cozy gray sofa sits nearby, alongside a lamp with a light shade. The kitchen area contains dark countertops and organized shelves, with large windows providing a city view.
Apartment in Panamá
4.9 out of 5 average rating, 166 reviews

Spacious Executive Apartment

Perfect location in the bank zone. Only a 10 minutes walk of “cinta costera” & Urraca Park where you can make exercise with a view! We are 1 minute walk to a very nice and big supermarket where you can get supplies. Area full of good restaurants and bars. We will enjoy to give you tips of where to have dinner, and any tips on turistical activities during your stay.

Popular amenities for Panama City apartment rentals

Quick stats about apartment rentals in Panama City

  • Total holiday rentals

    Explore 550 holiday rentals in Panama City

  • Nightly prices starting at

    Panama City holiday rentals start at $13 SGD per night before taxes and fees

  • Verified guest reviews

    Over 14,280 verified reviews to help you choose

  • Family-friendly holiday rentals

    200 properties offer extra space & child-friendly amenities

  • Pet-friendly holiday rentals

    Find 230 rentals that welcome pets

  • Holiday rentals with a pool

    370 properties feature pools

  • Rentals with dedicated workspaces

    380 properties have a dedicated workspace

  • Wifi availability

    530 of Panama City holiday rentals include wifi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi and Pool across Panama City rentals

  • 4.8 Average rating

    Panama City stays are highly rated by guests – averaging 4.8 out of 5!

  • Nearby attractions

    Panama City’s top spots include Miraflores Locks, Museo de Arte Contemporáneo and Santo Tomas (Panama Metro)

Destinations to explore