
Apartment holiday rentals in Panama City
Find and book unique apartments on Airbnb
Top-rated apartment rentals in Panama City
Guests agree: these apartments are highly rated for location, cleanliness and more.

Apto 4 min from Tocumen Airport | 24-hr check-in
Layover in Panama? Stay where everything is easy and comfortable Just 4 minutes from Tocumen International Airport – perfect for early flights or quick stopovers A modern, comfortable, and secure apartment with: • Fast WiFi and air conditioning • Smart lock and flexible check-in • 24/7 security • Pool, gym, and fully equipped kitchen • Steps from the ITSE Metro station Ideal for layover travelers, curious tourists, or business trips. 🌴 Just arrive — everything’s ready for you. We’ll be waiting!

Best Location – Spacious Luxury Apartment for 8
Welcome to our spacious and elegant apartment, designed to comfortably host up to 8 guests in the heart of Casco Viejo. Located directly in front of one of the most beautiful and lively plazas in the historic district, you’ll be surrounded by top restaurants, cafés, and vibrant city life. The building also features an elevator for your convenience and access to a rooftop, perfect for relaxing after a day exploring the city. Its prime location allows you to easily discover the best attractions

Apartment with unique views to remember
Pasarás una Experiencia con estilo, alojamiento céntrico. acceso a líneas de buses y el Metro, restaurante , grocery store 24 horas, y una vida nocturna genial, casinos, cinta costera, iglesia del Carmen. casco antiguo a minutos en uber. compras. Soho Mall, Multi Plaza Mall y Albrook Mall. Piscina para adultos y niños. Bar, restaurante, rooftop vistas panorámicas, coworking, gym. Una habitación Con cama queen y un sofá cama en la sala para huéspedes extras (costo xtra 15.00 pp x noche)

Casco Viejo 360° View Old Tower Penthouse
Located in one of the oldest buildings in Panama and set over 3 stories with unrivaled panoramic views over the historical Casco Viejo, the skyline of Panama City and views of the causeway, our gorgeous penthouse is the ideal space to take in the local sights, sounds, art, culture, socialize with your friends and family, or simply relax in a cozy love nest! Top speed wifi, excellent location, and fully equipped with all the home comforts, the penthouse is the perfect spot to explore Panama.

Luxury Mid-Century Apartment In Casco Viejo
Luxury mid-century one bedroom Boutiqe 72 m2 apartment. Step into the elegant, functional and comfortable place that we offer with love. The apartment located within a beautiful two-floors antique building in the heart of Casco Viejo. The apartment includes a well equipped brand new kitchen, a dining area and a spacious living room, also a balcony with a view of the lively streets below. The tranquil bedroom has an ensuite bathroom and a walking closet that fitting perfectly to your needs.

Luxury Balcony Stays + Pool Casco Viejo
Wake up overlooking one of the last historic bastions of Casco Viejo, sip your morning cofee on a private balcony, and step directly into Panama City most vibrant and wakable neighboorhood. Surrounded by colonial architecture, charming plazas, and a vibrant culinary scene, this space invites you to experience Panama with style and tranquility. Ideal for those seeking an exclusive, walkable, and characterful environment in one of the city's most iconic areas.

The apartment of a legendary Panamanian footballer
Location is everything – just steps away from the city’s best restaurants, bars, stunning churches, and fascinating museums. Explore the historic district on foot while enjoying the comfort of a stylish apartment featuring: • A spectacular balcony with beautiful views • A fully equipped kitchen • 1.5 bathrooms • Cozy beds that make you feel right at home • Surrounded by iconic calicanto stone walls that reflect the charm of Panama’s colonial past.

Amazing loft with an iconic view of Casco Viejo
Enjoy a unique experience, in this elegant and centrally-located loft. Fully remodeled 1 bedroom apartment, in a central location in Casco Viejo (the old city). You will be just steps away from many restaurants, cafes, museums, and the existing night life casco has to offer. Located in “Jeronimo,” this restored- colonial building was built in the year 1850, and features unique crafted wall décor, as well as some of the original "calicanto" walls.

The best view of the Old Town
Welcome to this charming accommodation in the heart of the Casco Viejo, located on the third floor facing one of Panama's most iconic squares, Plaza Catedral! Thanks to its prime location, you will enjoy a unique view of the square and the imposing Cathedral Church. Right in this lively square, you will have a wide variety of restaurants and shops at your disposal where you can buy souvenirs of this wonderful trip.

Full apartment in Panama
This charming apartment is located in one of the best neighborhoods in Panama, San Francisco, a downtown location where you will find ample cuisine, entertainment venues, close to bus stations, and the city's most important shopping mall, Multiplaza. This central and quiet apartment is an opportunity you won't want to miss. It offers the perfect combination of comfort, beauty, and a convenient location.

Modern, central and comfortable (001)
Modern and cozy studio in the heart of Panama. Perfect for exploring the Old Town, the Coastal Strip and more. Full kitchen, full bed, double sofa bed, air conditioning, fast WiFi and private bathroom. Ideal for 1–4 people. Private access, elevator and self check-in. Surrounded by restaurants, transportation, and tourist sites. Your ideal base to explore the city!

Exclusivo Ocean View 2BR/2BATH/Sky High & Rooftop.
Apartamento moderno de lujo en la Cinta Costera. Ideal para ejecutivos, parejas o familias. Dormitorio amplio con vista al mar, baño espacioso, diseño elegante y electrodomésticos modernos. Amenidades: seguridad 24/7, gimnasio, piscinas, 4 restaurantes, bar y Sky Lounge. Cerca de supermercados y una gran oferta gastronómica. Ciudad de Panamá – Panamá.
Popular amenities for Panama City apartment rentals
Weekly apartment rentals

Cozy apartment in Panama

Old Town & Ocean View

Luxury apartment in the heart of Panama

Unique Luxury 3-story Loft at the Yoo

Ocean View Suite Coastal Strip

La Fontana Spacious ApartaSuite - Pool 102

2-Bedroom Apt Ocean Views PH Yoo

Amazing experience in Casco Viejo historical site3
Private apartment rentals

Elegant apartment with a view & the warmth of home

Beautifull 1BR Apt With Comfy Hotel Linens

2BR King Suite Ocean View, Casco, Canal 500MB WIFI

Brand new spectacular 1B 1B Apartment

Luxury Oceanfront Resort 22nd Floor View, 200°

Spectacular Bay View • 1BR • Pool/Gym and +

"Arrive as guests. Leave feeling at home".

PH The Gray | Balcony Views · Pool · Gym
Apartment rentals with a hot tub

Suite Luxury 30th View Yoo Panamá & Arts Tower

Luxury 2BR Suite with Pool & Views

PH Yoo 44i – Ocean View Apartment

New Flat with Ocean + City Views

Apartment Av. Balboa, Yoo&Arts

Tropical Paradise at Playa Bonita

Panama Dream View Escape

Live the Wanders And Yoo Experience in Panama
Quick stats about flat rentals in Panama City

Total holiday rentals
Explore 2,860 holiday rentals in Panama City

Nightly prices starting at
Panama City holiday rentals start at $13 SGD per night before taxes and fees

Verified guest reviews
Over 88,500 verified reviews to help you choose

Family-friendly holiday rentals
920 properties offer extra space & child-friendly amenities

Pet-friendly holiday rentals
Find 1,130 rentals that welcome pets

Holiday rentals with a pool
1,940 properties feature pools

Rentals with dedicated workspaces
1,910 properties have a dedicated workspace

Wifi availability
2,790 of Panama City holiday rentals include wifi access

Popular amenities for guests
Guests love Kitchen, Wifi and Pool across Panama City rentals

4.7 Average rating
Panama City stays receive an average rating of 4.7 out of 5 from guests

Nearby attractions
Panama City’s top spots include Miraflores Locks, Museo de Arte Contemporáneo and Santo Tomas (Panama Metro)
Destinations to explore
- San Andrés Holiday rentals
- Puerto Viejo de Talamanca Holiday rentals
- Uvita Holiday rentals
- Boquete Holiday rentals
- Playa Blanca Holiday rentals
- Valle de Antón Holiday rentals
- Coveñas Holiday rentals
- Ancón Holiday rentals
- Bahía Ballena Holiday rentals
- Limon Holiday rentals
- David Holiday rentals
- Playa Venao Holiday rentals
- Rentals with outdoor seating Panama City
- Rentals with pools Panama City
- Family-friendly rentals Panama City
- Rentals with a fireplace Panama City
- Rentals with a washing machine and dryer Panama City
- Rentals with lake access Panama City
- Cabin rentals Panama City
- Hostel rentals Panama City
- Fitness-friendly rentals Panama City
- Rentals with beach access Panama City
- House rentals Panama City
- Smoking-friendly rentals Panama City
- Guest house rentals Panama City
- Apartment rentals Panama City
- Beachfront rentals Panama City
- Rentals with a firepit Panama City
- Boutique hotels Panama City
- Rentals with a patio Panama City
- Waterfront rentals Panama City
- Bed and breakfasts Panama City
- Rentals with a cinema Panama City
- Rentals with an EV charger Panama City
- Serviced apartment rentals Panama City
- Pet-friendly rentals Panama City
- Townhouse rentals Panama City
- Rentals with a sauna Panama City
- Hotel rooms Panama City
- Rentals with breakfast Panama City
- Rentals with an accessible-height bed Panama City
- Rentals with a hot tub Panama City
- Loft rentals Panama City
- Villa rentals Panama City
- Private suite rentals Panama City
- Flat rentals Panama







