
House holiday rentals in Panama City
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Top-rated house rentals in Panama City
Guests agree: these houses are highly rated for location, cleanliness and more.

Central|Confort|surrounded by nature|Wifi|parking
Conectar con la ciudad y la maravillosa naturaleza al mismo tiempo. Descansar en una hamaca en el balcón lo hace único. Te quedará genial si deseas visitarnos de placer, trabajo (WiFi de alta velocidad); en familia o en grupos de amigos. Casa de la Antigua Zona del Canal, Primer Alto; desde aquí para explorar lugares turísticos y restaurantes. (Cerca Terminal de Buses, Metro Tren, Albrook Mall, parque Metropolitano, Aeropuerto Marcos Gelabert, Casco Antiguo, Coast Way de Amador, Canal de 🇵🇦)

Cantabria House - 10 minutes from the Airport
Spacious and comfortable home just 10 minutes from Tocumen Airport and only 200 meters from the Metro. Perfect for families, groups, or business trips. Fast 500 Mbps Wi-Fi, 3 bedrooms, 2 full bathrooms, fully equipped kitchen, air conditioning throughout the house, cable TV, patio with outdoor furniture, private parking, and self check-in. Long layover, family trip, or work in the city? This home has it all: comfort, location, and privacy. Book now and feel at home from the very first moment!

Mountain Retreat
Relax and unwind at this peaceful property nestled on two hectares of lush tropical vegetation surrounded by the sights & sounds of nature. Located at Panama's Blue Mountain(Cerro Azul), 30 kilometres from Panama City. This cozy & comfortable home is equipped with modern amenities & chic decorative touches. It consists of a main house with 2 bedrooms & a 2 bedroom cottage. It has a spacious terrace, pool & jacuzzi overlooking Panama City. The property also boasts its own spring water well

Apartamento Lilia Airport 1
"Experimenta una estancia cómoda y conveniente en nuestro acogedor apartamento, ubicado a solo 10 minutos del aeropuerto Tocumen. Equipado con todas las comodidades necesarias para tu descanso, desde conexión WiFi hasta una cocina equipada, este espacio te ofrece la oportunidad de relajarte y recargar energías. Disfruta del confort del aire acondicionado, agua caliente/fria en el baño, una cama y sofá cama para tu comodidad, televisión con cable , y toallas y sobrecama para tu conveniencia.

King Beds | 4BR | BBQ & Garden | pets ok!
Nestled in a prime central location, this lovely house offers guests unparalleled convenience and uniqueness. Find yourself just a swift 10-minute Uber ride away from the bustling heart of downtown, making exploration and nightlife easily accessible. One of the standout features of our home is the exclusive view of the Metropark, which you can relish from both the backyard and balcony – a serene panorama that's hard to beat. Finally sleep in supreme comfort with king-sized beds featured.

Large Private Residence in an Excellent Area
House in the best areas of the country. Very quiet street, downtown, near restaurants, pharmacies, malls among others. Large comfortable residence for groups or families. Private parking for up to 2 cars 4 Spacious bedrooms, 2 comfortable studios, living room, breakfast room, large terrace. *Opcion Kosher Disponible* House in one of the best area of the country. Very quiet street, central, close to restaurants, pharmacies, mall and more. Large comfortable residence for groups.

Spacious Panama House in the 'heart of the city'
You couldn't ask for a better place to stay while you visit Panama. This location is perfect, while other properties might advertise similar amenities; not one of them can boast a combination of space and amazing location quite like this one. This is very private & secure property in a fantastic, & very safe area right in the heart of the city & close to everything! An oasis in the middle of the city with AC IN EVERY ROOM AND DININING ROOM.

Full house, pool, jacuzzi, private rooftop
¡Bienvenido a Casa Compadre, tu hogar ideal en el histórico Casco Viejo de Panamá! Esta espaciosa y elegante casa cuenta con 4 cómodas habitaciones y capacidad para hasta 10 personas. Perfecta para grupos o familias, ofrece una sala de billar para el entretenimiento, espacios bien decorados y todas las comodidades para una estancia inolvidable. Disfruta de una estadía inolvidable en un ambiente acogedor y completamente equipado.

Exceptional three-story building with sea view
This stunning three-story property, located in Casco Viejo, boasts a terrace with a sea view. Designed with a focus on elegance and relaxation, the house features spacious and well-lit interiors adorned with modern and high-quality decor. The strategic location of the house allows for breathtaking views from the terrace, offering a unique blend of luxury and relaxation in a historic and picturesque setting.

Comfortable and luxurious apartment
Enjoy a stylish experience at our home in Casco Antiguo, take advantage of the location close to art galleries, restaurants, crafts,etc. Our house has three bedrooms each with balcony, bathroom and closet, with a nice equipped contemporary kitchen; a spacious living room and dining area. You have a total area of 326 mts² The entire house surrounded by balconies where you can enjoy the panoramic views.

Private Studio 10 Min from the Airport!
Entire apartment 10 minutes from the airport! The apartment is fully furnished including appliances and kitchen items, toiletries, dining room, work table and more. Just a few minutes walk from the SAN ANTONIO METRO Station, restaurants, shopping malls, laundries, supermarkets and pharmacies. We offer tours to San Blas to make the most of your trip. Our house is your house in Panama 🇵🇦

Casa Santa by SS • 3BR Perfect Stay Near City
This memorable place is anything but ordinary. This stylish place is perfect for group of persons or family trips. Conveniently located next to shopping malls and supermarkets you’re literally minutes from the train station and just minutes to the city. San Antonio is a safe place for families. Enjoy a cozy silent place with everything you can need for your stay.
Popular amenities for house rentals in Panama City
House rentals with a pool

Luxurious beachfront home in Veracruz

Luxury Home with Pool in the Best Neighborhood

house 2 bedrooms, 2 bathrooms, kitchen, dining room, in ancon

A beautiful apartment with a swimming pool, BBQ area, and gym

Beautiful house in Brisas del Golf

Villa Helena 3 Bedrms Los Altos de Cerro Azul

House of the waterfalls

Airbnb - Vacation
Weekly house rentals

HOUSE Panama City Albrook 3 story house 3 bedroom

Modern and minimalist Altos de Cerro Azul

Country house in Altos de Cerro Azul

Cabin in Cerro Azul with Forest View

Casa de Montaña Altos de Cerro Azul

La Canelita at Cerro Azul, Panama

My Blue Escape

Hello Panama! Brisas del Golf
Private house rentals

2 bedroom apartment in the heart of Panama

villa serena

A nice house equipped for rest or home office

Specious house that can accommodate up to seven

Family House | 4 floors | BBQ | 20 Pax | Views

LovelyviewPty House 15 minutes away from the airport

Residence in Panama

Oceanfront views/access w/ Pool, Privacy & Space
Quick stats about house rentals in Panama City

Total holiday rentals
Explore 470 holiday rentals in Panama City

Nightly prices starting at
Panama City holiday rentals start at $13 SGD per night before taxes and fees

Verified guest reviews
Over 7,270 verified reviews to help you choose

Family-friendly holiday rentals
180 properties offer extra space & child-friendly amenities

Pet-friendly holiday rentals
Find 160 rentals that welcome pets

Holiday rentals with a pool
90 properties feature pools

Rentals with dedicated workspaces
220 properties have a dedicated workspace

Wifi availability
430 of Panama City holiday rentals include wifi access

Popular amenities for guests
Guests love Kitchen, Wifi and Pool across Panama City rentals

4.7 Average rating
Panama City stays receive an average rating of 4.7 out of 5 from guests

Nearby attractions
Panama City’s top spots include Miraflores Locks, Museo de Arte Contemporáneo and Santo Tomas (Panama Metro)
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