Boutique hotels in St. Louis

Find and book unique boutique hotels on Airbnb

Top-rated boutique hotels in St. Louis

Guests agree: these boutique hotels are highly rated for location, cleanliness and more.

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Guest favourite
Hotel room in Midtown
4.94 out of 5 average rating, 160 reviews

Chic Ultramodern Studio Loft w/ Designer Features

The Nash Loft is a stunning minimalist studio with 12’ ceilings, a fully-equipped kitchen with black stainless appliances and quartz countertops, a spacious walk-in closet, stackable washer + dryer, a designer bathroom with black stainless fixtures and frameless glass shower, and bright 7’ industrial steel-frame windows with views of the tree-lined street and shops below. Situated along the famous Locust Street in the heart of Midtown, you’ll be steps from SLU, Wells Fargo, BJC, and the Grove.

Guest favourite
Hotel room in Midtown
4.9 out of 5 average rating, 134 reviews

Chic Ultramodern Studio Loft w/ Designer Features

The Nash Loft is a stunning minimalist studio with 12’ ceilings, a fully-equipped kitchen with black stainless appliances and quartz countertops, a spacious walk-in closet, stackable washer + dryer, a designer bathroom with black stainless fixtures and frameless glass shower, and bright 7’ industrial steel-frame windows with views of the tree-lined street and shops below. Situated along the famous Locust Street in the heart of Midtown, you’ll be steps from SLU, Wells Fargo, BJC, and the Grove.

Hotel room in Central West End
4.76 out of 5 average rating, 116 reviews

The West End by Cortex, Forest Park, BJC & Zoo

Welcome to The West End, your ideal retreat in the heart of the Central West End! Just steps away from charming attractions like forest park. Great amenities are: - Fast and stable fiber internet connection - Communal kitchen with 2 sets of range, ovens, fridges, microwaves, and dishwashers. - Complimentary coffee - Secured Gated Parking $10/Night - Hot Tub - Great patio space with seating and a gas grill - Complimentary Netflix, Hulu, Disney+, and ESPN+, where available and local TV channel

Guest favourite
Hotel room in Midtown
4.93 out of 5 average rating, 122 reviews

Chic Ultramodern Loft Suite w/ Designer Features

The Nash Loft is a stunning minimalist one-bedroom suite with 12’ ceilings + bright 7’ industrial steel-frame windows, a spacious open layout, stackable washer + dryer, a designer bathroom with black stainless fixtures and frameless glass shower, an Edison-illuminated community courtyard, and a fully-equipped kitchen with black stainless appliances and quartz countertops. Situated along the famous Locust Street in the heart of Midtown, you’ll be steps from SLU, Wells Fargo, BJC, and the Grove.

Guest favourite
The exterior of a two-story building is shown, featuring a red brick ground floor and a silver metal-clad upper level. A striped awning extends over the entrance, where a sign indicates the establishment serves wine and craft beers. Two flags are displayed near seating arranged outside.
Hotel room in Alton
4.95 out of 5 average rating, 44 reviews

Three Bedroom River View Guest House-3 Bathrooms

An escape from the ordinary in our River view guest house. On bottom level is an art glass shop offering classes in stained , fused, and mosaic art glass you may partake in at an additional cost. Bicycle built for two available for cycling the national scenic byway. Walk to shops, casino, restaurants, breweries, and concerts. Cruise ship dock is 1/2 mile away. Extend your stay before or after to enjoy taking a stained glass class offered in our shop below as a souvenir of your trip.

Guest favourite
The spacious common area features an open kitchen with a dark granite countertop, blending modern functionality with historic charm. Two large stained glass windows cast colorful light throughout the room, while a grand staircase leads to an upper level, showcasing the building's architectural elegance.
Hotel room in Dogtown
4.98 out of 5 average rating, 54 reviews

Luxury Retreat, Hot Tub,En-Suite Bath, Location+

Discover refined elegance in The Riverfront Suite, where Gothic grandeur meets contemporary comfort. This distinctive retreat showcases original stained glass windows and exotic wood finishes . A plush queen bed and ambient electric fireplace create an intimate atmosphere, while the luxurious en-suite bathroom features heated floors, designer tile work, and a 2-person soaking tub. Take in panoramic city views from the shared rooftop hot tub. Perfect for couples seeking a romantic escape.

Superhost
Hotel room in Central West End
4.86 out of 5 average rating, 762 reviews

Blue Spruce Room Queen Bed at BnB in CWE!

A Lovely room in a historical St. Louis home! The Blue Spruce Room is on the 2nd floor, and has a recently renovated and beautiful bathroom complete with a walk-in rain shower right next to it. The room has a desk, chair, lamp, table, Amazon Fire TV with basically every major streaming App, newly installed hardwood floors, and a Queen sized-bed. The room has two large windows for plenty of natural light with heavy blinds for sleeping in! Full use of the kitchen upstairs is available!

Guest favourite
Hotel room in Central West End
4.86 out of 5 average rating, 810 reviews

The Maple Room Queen Bed at BnB in CWE!

A Lovely room in a historical St. Louis home! The Blue Spruce Room is on the 2nd floor, and has a recently renovated and beautiful bathroom complete with a walk-in rain shower right next to it. The room has a desk, chair, lamp, table, Amazon Fire TV with basically every major streaming App, newly installed hardwood floors, and a Queen sized-bed. The room has two large windows for plenty of natural light with heavy blinds for sleeping in! Full use of the kitchen upstairs is available!

Guest favourite
Hotel room in Midtown
4.91 out of 5 average rating, 163 reviews

Chic Ultramodern Studio Loft w/ Designer Features

The Nash Loft is a stunning minimalist studio with 12’ ceilings + bright 7’ industrial steel-frame windows, a spacious open layout, stackable washer + dryer, a designer bathroom with black stainless fixtures and frameless glass shower, an Edison-illuminated community courtyard, and a fully-equipped kitchen with black stainless appliances and quartz countertops. Situated along the famous Locust Street in the heart of Midtown, you’ll be steps from SLU, Wells Fargo, BJC, and the Grove.

Top guest favourite
The living area features exposed brick walls and large industrial windows, allowing natural light to fill the space. A modern leather sofa is paired with a geometric coffee table, while a dining table with place settings completes the inviting atmosphere. A cozy area rug adds warmth.
Hotel room in Midtown
4.9 out of 5 average rating, 171 reviews

Gorgeous Ultramodern 2BR Corner Loft + Workspace

The Nash Loft is a stunning corner loft with two spacious bedrooms, two designer bathrooms with black stainless fixtures and frameless glass showers, 12’ ceilings, a comfortable workspace with high-speed internet connection, stackable washer + dryer, an Edison-illuminated community courtyard, and a fully-equipped kitchen with black stainless appliances. Situated along the famous Locust Street in the heart of Midtown, you’ll be steps from SLU, Wells Fargo, BJC, and the Grove.

Superhost
A modern living area features large windows that frame views of surrounding greenery. Four white armchairs are arranged around a central coffee table, complemented by a cozy beige sofa. Soft lighting is provided by a decorative ceiling fixture, enhancing the space's brightness.
Hotel room in Cottleville

Penthouse Suite

Room 301 2 bedroom Queen, King room Oak Street Inn & Lounge, 8 Room Boutique hotel situated in the bustling center of downtown Cottleville. Oak Street Inn & Lounge will offer an elegant restaurant and craft cocktail lounge on the ground floor Indulge in room service from Pink Willow Cafe, or dine in! Come up to the rooftop patio on the third level for a cocktails, small bites and breathtaking views of Cottleville. Look for our Hidden Gem the Speakeasy in the lower level!

Top guest favourite
Hotel room in Midtown
4.94 out of 5 average rating, 115 reviews

Chic Ultramodern Studio Loft w/ Designer Features

The Nash Loft is a gorgeous studio loft with 12’ ceilings, a fully-equipped kitchen with black stainless appliances and quartz countertops, stackable washer + dryer, a designer bathroom with black stainless fixtures and frameless glass shower, a comfortable workspace with high-speed internet connection, and an Edison-illuminated community courtyard. Situated along the famous Locust Street in the heart of Midtown, you’ll be steps from SLU, Wells Fargo, BJC, and the Grove.

Popular amenities for St. Louis boutique hotels

When is the best time to visit St. Louis?

MonthJanFebMarAprMayJunJulAugSepOctNovDec
Avg. price$83 SGD$90 SGD$100 SGD$101 SGD$129 SGD$141 SGD$140 SGD$117 SGD$106 SGD$114 SGD$130 SGD$106 SGD
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Quick stats about boutique hotels in St. Louis

  • Total holiday rentals

    Explore 30 holiday rentals in St. Louis

  • Nightly prices starting at

    St. Louis holiday rentals start at $76 SGD per night before taxes and fees

  • Verified guest reviews

    Over 6,290 verified reviews to help you choose

  • Pet-friendly holiday rentals

    Find 20 rentals that welcome pets

  • Rentals with dedicated workspaces

    30 properties have a dedicated workspace

  • Wifi availability

    30 of St. Louis holiday rentals include wifi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi and Pool across St. Louis rentals

  • 4.9 Average rating

    St. Louis stays are highly rated by guests – averaging 4.9 out of 5!

  • Nearby attractions

    St. Louis’s top spots include Busch Stadium, Saint Louis Zoo and Enterprise Center

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