
Holiday rentals in Panama City
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Quick stats about holiday rentals in Panama City

Total holiday rentals
Explore 5,590 holiday rentals in Panama City

Verified guest reviews
Over 149,670 verified reviews to help you choose

Family-friendly holiday rentals
1,780 properties offer extra space & child-friendly amenities

Pet-friendly holiday rentals
Find 1,940 rentals that welcome pets

Holiday rentals with a pool
2,960 properties feature pools

Rentals with dedicated workspaces
3,570 properties have a dedicated workspace

Wifi availability
5,430 of Panama City holiday rentals include wifi access

Popular amenities for guests
Guests love Self check-in, Gym and BBQ grill across Panama City rentals

4.7 Average rating
Panama City stays receive an average rating of 4.7 out of 5 from guests

Nearby attractions
Panama City’s top spots include Miraflores Locks, Museo de Arte Contemporáneo and Santo Tomas (Panama Metro)
Top-rated holiday rentals in Panama City
Guests agree: these stays are highly rated for location, cleanliness and more.

Studio for the Coffee-Obsessed | near Casco Viejo
Panama produces some of the world's most celebrated coffees — and this studio puts you right where the flavor meets the culture. A third-floor, well-designed space in Santa Ana, walking distance from Casco Viejo and a short trip from the best specialty cafés in Panama City. 📍 Location (Important – Please Read) The studio is NOT inside Casco Viejo, but: • 2–3 minutes by Uber ($2–$3) • 8–10 minute walk Santa Ana has a long café culture of its own — and the specialty coffee scene nearby is genui

Luxury apt in Panama City 2 Rooms 3 Baths
El edificio Wanders by yoo esta ubicado en el corazón de la ciudad, es un proyecto fuera de serie donde cada rincón tiene una historia que contar. Recepción 24/7, muchas areas de esparcimiento, estación de hidratación. En las afueras del lobby tenemos la Cafetería cafe con teclas y un restaurante de Carnes Popino. En el area social servicio de barra en la piscinas, parque de niños, sala de juegos con pantallas en e l techo baños, salon de eventos, cocina para eventos, gym full equipado y más

CASA SAEMA -PRESTIGIOSO ATICO DUPLEX CON TERRAZAS
Espectacular ático Duplex en Panamá Casco antiguo, de 265 M2 con balcones, terrazas privadas exterior, cuenta con una salón jardín interior, un comedor, 3 hab. (+ sofá cama en studio), recientemente reformado con concepto Loft, diseño exclusivo único y confortable, en la mejor zona del Casco viejo, perfecto para relajarse y desconectar, cocina , lavavajilla, sala con lavadora. piscina compartida, asc, portero 24-7, no se permiten niños que no sepan nadar, gran variedad de ocio en la zona.

Modern apt ocean view in heart of Panamá yoo tower
Este lugar tiene una ubicación estratégica: ¡será muy fácil planear tu visita! Ph Yoo and Arts, ubicado en Av. Balboa, súper céntrico Esta hermosa y moderna propiedad cuenta con un estilo único y una vista al mar increíble, piso alto, 2 habitaciones, 2.5 baños completos, Lavanderia, amplia terraza, luces dimeables en todo el espacio, sala comedor, sala de películas, espacio de trabajo, 3 smart tvs, 3 aires acondicionados céntrales, cocina full equipada, cristalería moderna.

The View of Casco: Designer Loft with best Balcony
Sip your morning coffee or evening wine on the balcony, taking in a stunning, panoramic view of the city skyline! Experience the absolute best of Casco Viejo from this elegant, fully remodeled 1-bedroom loft. Nestled inside a beautifully restored 1850 colonial building—featuring historic, original calicanto walls—this stylish space puts the entire city at your doorstep. You are just steps away from world-class dining, vibrant cafes, museums, and Casco's legendary nightlife

Unique Luxury 3-story Loft at the Yoo
Experience the luxury of a world renowned Philippe Starck designed building. Our 3-bedroom sanctuary is a unique 3-story loft that boasts breathtaking city views, an open-plan kitchen, sleek marble floors, and premium amenities. Steps away from Panama City’s premier attractions, shopping, and dining. Dive into top-tier amenities: a pristine pool, state-of-the-art gym, relaxing spa, and three of the best restaurants in the city! Embrace Panama in unmatched style.

Beautiful House in Panama w/ King Beds + Pool
Beautiful home in Punta Paitilla featuring 6 bedrooms, 5.5 bathrooms, and 8 beds, comfortably accommodating up to 16 guests. Enjoy a private pool, in-home gym, and spacious, modern living areas designed for families, groups, or business travelers. The layout offers both privacy and comfort across two levels. Located in one of Panama City’s most exclusive neighborhoods, just minutes from restaurants, shopping centers, supermarkets, and the Cinta Costera.

Apartamento completo en Panama
Este encantador apartamento está ubicado en uno de los mejores barrios de Panamá, San Francisco, un lugar céntrico donde encontrarás amplía gastronomía, lugares de diversión, cerca a estaciones de buses, y al centro comercial más importante de la ciudad, Multiplaza. Este apartamento céntrico y tranquilo es una oportunidad que no querrás dejar pasar. Ofrece la combinación perfecta de comodidad, belleza y ubicación conveniente.

Beautiful Apt, Best Location 2BR
Beautiful apartment, high floor up, with 2 bedrooms, 2 bathrooms, walking closet, and essential closet for the second bedroom. Extra twin bed available in the apartment. High speed internet, 300Mbps by Wifi aprox. , 600Mbps by cable. Social area on the roof with swimming pool, gym, sauna and bbq area. The building location is excellent, We are walking distance for grocery stores, restaurants, bank, Hilton Hotel&Casino.

Hotel-Style Room at The Hub, San Francisco
Elegante habitación estilo hotel en PH The Hub, ubicado en Calle 74, y calle 50 en San Francisco, a pocos pasos del Parque Omar. Ideal para un máximo de 2 personas, cuenta con baño privado completo, balcón, mini refrigerador, microondas, cafetera y tetera eléctrica. Disfruta de las amenidades del edificio como piscina, gimnasio y seguridad 24/7, en uno de los barrios más vibrantes de la Ciudad de Panamá.

Vista al Mar Panamá City
Impresionantes vistas al mar y al Casco Antiguo, con acceso directo al complejo turístico Poin Panamá, como una variedad ofertas gastronómicas y bares, para una experiencia vacacional sin igual. ⚠️ Aviso importante: La piscina y el gimnasio del edificio estarán temporalmente cerrados por trabajos de mantenimiento del 24 de agosto al 15 de septiembre de 2026. Agradecemos su comprensión.

Casco Antiguo & Ocean View
Impresionantes vistas al mar y al Casco Antiguo, con acceso directo al complejo turístico Poin Panamá, como una variedad ofertas gastronómicas y bares, para una experiencia vacacional sin igual. ⚠️ Aviso importante: La piscina y el gimnasio del edificio estarán temporalmente cerrados por trabajos de mantenimiento del 24 de agosto al 15 de septiembre de 2026. Agradecemos su comprensión.
Popular amenities for Panama City holiday rentals
Other great holiday rentals in Panama City

Suite Luxury 30th View Yoo Panamá & Arts Tower

Mountain Retreat

Luxury Oceanfront Resort 22nd Floor View, 200°

Panoramic Casco Viejo Lookout in The Sands

Elegante PH Yoo 1 Dormitorio Renovado

Casa del Horno | Un Fragmento de historia panameña

YC 3403 l Apartamento 1 BDR av. Balboa con balcon

Apartamento de Lujo frente al mar en cinta costera
Frequently Asked Questions
What are the best places to stay in Panama City?
Panama City has stays in vibrant neighborhoods like Casco Viejo, known for historic charm, and Punta Pacifica, often suggested for modern towers and city views. Many visitors also enjoy options around El Cangrejo for its mix of cafes and local culture.
What are the best things to do in Panama City with kids?
Explore the Biomuseo’s interactive exhibits, walk the Amador Causeway for city and canal views, or visit parks like Parque Natural Metropolitano to spot wildlife. Many families enjoy boat tours or learning about the canal’s history.
What are some of the best things to do in Panama City?
Wander historic streets in Casco Viejo, explore exhibits at the Panama Canal Museum, and stroll the Cinta Costera waterfront. Food and markets, canal tours, and cultural centers are frequently suggested for first-time visitors.
How is the weather in Panama City?
Panama City has a tropical climate with warm temperatures year-round, often around 75–88°F (24–31°C). Visitors can expect higher humidity, with occasional rain, especially during the wet season.
What are the best places to visit in Panama City?
Casco Viejo’s historic architecture, the Panama Canal, and the Biomuseo are often highlighted for visitors. The Amador Causeway is also suggested for scenic walks and views over the bay.
What are some hiking trails in Panama City?
Parque Natural Metropolitano has trails through tropical forest with city vistas and wildlife. The Sendero El Gaital path and walking routes around Cerro Ancón are also frequently suggested for those who want a nature escape near urban sights.
What are some family activities we can do in Panama City?
Families often enjoy the interactive displays at Biomuseo, relaxing on the Amador Causeway, and wildlife spotting in Parque Natural Metropolitano. Parks with playgrounds and canal boat tours are also popular with kids.
What are some of the best day trip ideas from Panama City?
Day trips from Panama City often include hiking in nearby rainforest reserves, visiting Gamboa for canal views and nature tours, or relaxing on beaches around the Pearl Islands. Guided excursions introduce travelers to indigenous cultural sites as well.
Are there any pet friendly accommodations available in Panama City?
Panama City has pet-friendly stays, especially in neighborhoods like El Cangrejo and San Francisco, where parks and walkable streets make it easy to enjoy the city with your pet. Many hosts welcome dogs and cats with advance notice.
What are some local tips for visiting Panama City?
When exploring Panama City, lightweight clothing helps with humidity, and a reusable water bottle is useful. Street murals around Casco Viejo show local talent, while trying fresh seafood in city markets gives a taste of regional flavors.
What is Panama City known for?
Panama City is known for the Panama Canal, mix of colonial and modern architecture, and vibrant culinary scene. Its waterfront walks and lively festivals celebrate a crossroads of cultures.
What are the best hidden gems to explore in Panama City?
Panama City has tucked-away art galleries in Casco Viejo, quiet gardens at Mi Pueblito, and street food stands in Santa Ana that attract locals. Seek out small museums and indie coffee shops for a neighborhood experience.
What are the best foods to try in Panama City?
Local favorites include sancocho chicken stew, patacones (fried plantains), and ceviche from city markets. Panamanian seafood, fresh tropical fruits, and pastries filled with local flavors are frequently suggested.
What should I bring for a trip to Panama City?
Bring lightweight, breathable clothing for the tropical climate, comfortable walking shoes, and sun protection like hats and sunscreen. A rain jacket and an adapter for electronics are also practical for your stay.
What is the nightlife in Panama City like?
Panama City has a vibrant nightlife scene, with lively rooftop bars, salsa venues, and music lounges in Casco Viejo. Neighborhoods like Calle Uruguay and El Cangrejo are known for dance clubs, craft cocktail spots, and casual pubs. Visitors often explore a mix of local rhythms and international influences after dark.
What are the most popular events or festivals in Panama City?
Carnival is one of the most popular celebrations, filling Panama City with music, parades, and color before Lent. Jazz festivals, local art fairs, and folklore events also draw crowds throughout the year.
Are there family friendly vacation rentals in Panama City?
Panama City has family-friendly vacation rentals, especially in areas near parks and cultural attractions like El Cangrejo, San Francisco, and Casco Viejo. Many hosts provide amenities for children and groups traveling together.
When is the best time to visit Panama City?
The drier season is often recommended for clearer skies and outdoor activities. Many travelers prefer visiting when major cultural events and festivals enliven the city’s atmosphere.
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