Some info has been automatically translated. Show original language

Holiday rentals in Panama City

Find and book unique accommodation on Airbnb

Top-rated holiday rentals in Panama City

Guests agree: these stays are highly rated for location, cleanliness and more.

%{current} / %{total}1 / 1
Top guest favourite
Flat in Obarrio
5 out of 5 average rating, 14 reviews

Modern apartment in the heart of Obarrio

This apartment stands out for its privileged location in Obarrio, with a modern and cozy design. Located on the 14th floor, it offers a spectacular view, its decoration in neutral tones conveys serenity. The convenience of having two bathrooms makes it unique. Ideal for travelers seeking tranquility and functionality. Located a few steps from 50th Street and the iconic El Tornillo building. You are surrounded by casinos, hotels and restaurants. Safe area for walking and enjoying the city.

Top guest favourite
A modern living area features a light-colored sofa adorned with colorful cushions. A round coffee table sits on a textured rug, while a dining table for six is visible in the background. Large windows present striking views of the city skyline.
Flat in Panama City
5 out of 5 average rating, 37 reviews

Luxury apt in Panama City 2 Rooms 3 Baths

El edificio Wanders by yoo esta ubicado en el corazón de la ciudad, es un proyecto fuera de serie donde cada rincón tiene una historia que contar. Recepción 24/7, muchas areas de esparcimiento, estación de hidratación. En las afueras del lobby tenemos la Cafetería cafe con teclas y un restaurante de Carnes Popino. En el area social servicio de barra en la piscinas, parque de niños, sala de juegos con pantallas en e l techo baños, salon de eventos, cocina para eventos, gym full equipado y más

Superhost
Flat in Panamá
5 out of 5 average rating, 4 reviews

Incredible Renovated Apartment in Casco Viejo

Disfruta de un loft único en el corazón de Casco Viejo, ubicado en la emblemática Calle 4ta. Este apartamento ha sido totalmente remodelado, combinando a la perfección el encanto histórico de sus muros originales con un diseño moderno y elegante. La doble altura, la pared de piedra restaurada y los detalles artesanales en los pisos crean un ambiente acogedor y sofisticado. Su distribución abierta con sala, comedor y cocina integrada lo convierten en un espacio ideal para relajarse y compartir.

Guest favourite
A modern living area features a large wave mural that enhances the space's vibrant decor. Comfortable seating arrangements include a sleek white sofa and a pair of stylish armchairs. A glass coffee table is centered among the furnishings, with tastefully arranged decorative accents.
Serviced apartment in Panamá
4.93 out of 5 average rating, 262 reviews

Modern apt ocean view in heart of Panamá yoo tower

Este lugar tiene una ubicación estratégica: ¡será muy fácil planear tu visita! Ph Yoo and Arts, ubicado en Av. Balboa, súper céntrico Esta hermosa y moderna propiedad cuenta con un estilo único y una vista al mar increíble, piso alto, 2 habitaciones, 2.5 baños completos, Lavanderia, amplia terraza, luces dimeables en todo el espacio, sala comedor, sala de películas, espacio de trabajo, 3 smart tvs, 3 aires acondicionados céntrales, cocina full equipada, cristalería moderna.

Guest favourite
A spacious living area features a combination of modern and vintage furnishings. A large turquoise sofa and a floral chaise lounge are complemented by a round coffee table and a green wooden chair. Exposed stone walls and large windows with blue accents create a warm ambiance.
Flat in Panamá
4.98 out of 5 average rating, 146 reviews

Escape to the Heart of Casco with a Private Balcony

Location is everything – just steps away from the city’s best restaurants, bars, stunning churches, and fascinating museums. Explore the historic district on foot while enjoying the comfort of a stylish apartment featuring: • A spectacular balcony with beautiful views • A fully equipped kitchen • 1.5 bathrooms • Cozy beds that make you feel right at home • Surrounded by iconic calicanto stone walls that reflect the charm of Panama’s colonial past.

Guest favourite
A modern living area is showcased, featuring a light gray sofa positioned across from a flat-screen TV on a wooden console. Two abstract art pieces adorn the walls. Floor-to-ceiling windows offer views of the city skyline, enhancing natural light in the space.
Apartment in Panamá
4.94 out of 5 average rating, 127 reviews

Beautiful Apartment 3 guests

Moderno, elegante y cómodo departamento, cerca de todo! Restaurantes, farmacias, supermercados, canchas de padle, a pocos minutos del centro comercial Multiplaza. Totalmente amoblado, 1 recamara, 1 baño completo, walking closet, cocina, sala, área de desayunador, lavadora-secadora y balcón. Para su disfrute, piscina de agua salada en el último piso, gimnasio, espacio de co-working, incluye un espacio de estacionamiento con valet parking.

Top guest favourite
An outdoor pool area is featured with modern sun loungers surrounding the illuminated water. Lounge furniture provides space for relaxation, while the skyline of the city is visible in the background against a twilight sky.
Flat in Marbella
5 out of 5 average rating, 55 reviews

Modern and luxurious Costera Cinta

Experience the luxurious PH Yoo experience with city views in this elegant apartment with king bed and floor-to-ceiling windows. Enjoy upscale amenities: swimming pool, gym, squash court, spa, and more. Privileged location close to tourist areas, restaurants, bars and malls. Inside the building there are gastronomic options with exclusive discounts and free valet parking. Modern, spacious and sophisticated space for an unforgettable getaway.

Guest favourite
An aerial view showcases a vibrant pool area featuring a flower-patterned design, surrounded by lounge chairs and numerous umbrellas. A hot tub is positioned beside the pool, with the modern building rising in the background, adding a sleek architectural element.
Serviced apartment in Panama City
5 out of 5 average rating, 10 reviews

Luxury apartment in the Panamá city

This apartment perfectly combines comfort, style, and location. You'll love its modern design, impeccable cleanliness, and peaceful atmosphere. It's equipped with everything you need to feel at home and offers a beautiful view. Plus, you'll be in a prime location, close to restaurants, shopping centers, and with easy access to transportation. Ideal for business trips or simply enjoying the city from a comfortable and stylish location.

Top guest favourite
An inviting living area is featured, showcasing a modern grey sofa accented with decorative pillows. A round glass dining table is surrounded by chairs, and artistic wall frames complement the space. Natural light is filtered through elegantly layered window shades.
Flat in Panamá
4.97 out of 5 average rating, 116 reviews

Luxury apartment in downtown Panama, banking area

We have a strategic location right on the main road of Panama (Calle 50) Bella Vista. You will find yourself located in the heart of the banking area. Whether you're coming for work or vacation, this is the ideal place. You'll find all kinds of restaurants, shops, and shopping malls nearby. You'll have the Cinta Costera just a 10-minute walk away where you can walk or exercise. Fun and enjoyment within walking distance

Guest favourite
Flat in Panamá
5 out of 5 average rating, 117 reviews

Full apartment in Panama

This charming apartment is located in one of the best neighborhoods in Panama, San Francisco, a downtown location where you will find ample cuisine, entertainment venues, close to bus stations, and the city's most important shopping mall, Multiplaza. This central and quiet apartment is an opportunity you won't want to miss. It offers the perfect combination of comfort, beauty, and a convenient location.

Top guest favourite
Apartment in Panama
4.99 out of 5 average rating, 256 reviews

Patty’s Cozy Studio with K bed in Casco Viejo

Best location by the “El Rey" Supermarket...Casco's only grocery store! Prime location steps away from restaurants, bars, cafes, plazas and great little breakfast places with the lovely water front promenade around the corner making it the perfect “pied-à-terre!” The studio has a fully stocked kitchen aside from the main living space. It is spacious, comfortable and tastefully decorated!

Guest favourite
A private terrace features a jacuzzi surrounded by lush greenery against an exposed stone wall. Wooden decking creates a warm ambiance, complemented by two lounge chairs designed for relaxation, offering an inviting outdoor space for guests.
Flat in Panama City
4.9 out of 5 average rating, 153 reviews

Jacuzzi in colonial ruins in beautiful apartment

Welcome to Casa Marquez Portazgo! This cozy apartment in the heart of Panama City offers comfort and convenience, ideal for your stay. With one bedroom and capacity for two people, you'll enjoy a relaxing atmosphere in 70 m². Located in the San Felipe neighborhood, just steps from the entrance to the Casco Antiguo, it offers a unique experience. You can also unwind in the jacuzzi.

Popular amenities for Panama City holiday rentals

Quick stats about holiday rentals in Panama City

  • Total rentals

    4.7K properties

  • Nightly prices starting at

    $13 SGD before taxes and fees

  • Total number of reviews

    114K reviews

  • Family-friendly rentals

    1.5K properties are a good fit for families

  • Pet-friendly rentals

    1.7K properties allow pets

  • Rentals with a pool

    2.6K properties have a pool

Destinations to explore

  1. Airbnb
  2. Panama
  3. Panamá Province
  4. Panama City