
House holiday rentals in Seneca
Find and book unique houses on Airbnb
Quick stats about house rentals in Seneca

Total holiday rentals
Explore 40 holiday rentals in Seneca

Nightly prices starting at
Seneca holiday rentals start at $65 SGD per night before taxes and fees

Verified guest reviews
Over 1,930 verified reviews to help you choose

Family-friendly holiday rentals
30 properties offer extra space & child-friendly amenities

Pet-friendly holiday rentals
Find 20 rentals that welcome pets

Rentals with dedicated workspaces
20 properties have a dedicated workspace

Wifi availability
40 of Seneca holiday rentals include wifi access

Popular amenities for guests
Guests love Kitchen, Wifi and Pool across Seneca rentals

4.9 Average rating
Seneca stays are highly rated by guests – averaging 4.9 out of 5!
Top-rated house rentals in Seneca
Guests agree: these houses are highly rated for location, cleanliness and more.

Hanover Haven 3 BR/2 Bath
Hanover Haven is located close to all you need! Clemson University is only 3 miles away. There are 3 full grocery stores within 5 minutes. Lake Keowee access and marina all within 5 miles. The Gathering space is such a great place to have family fun! There are card games and large TVs with multiple streaming platforms. We are also working on a great outdoor space that will include a grill and sail shade ready for the summer. There is also an RV on the property that is an AirBNB with privacy.

Modern Lake Vibes – Kayaks, Dock & Fireplace
The perfect home for lake lovers and college football fans. Located just ~5 minutes away from Clemson and Death Valley, the newly renovated lakefront cottage will be the perfect stay for you, your family, and friends. With an outdoor fire pit, amazing views, boat dock, kayaks, and a modern kitchen, this retreat has all the amenities you're looking for inside and out! Whether you spend your time relaxing at the house, cheering on the Tigers, or fishing the lake, the Hideaway is sure to please.

Valhalla: Cliff-Edge Suite · Forest Views · Tub
VALHALLA – The Ultimate Romantic Retreat 🏔️🥂✨ Perched above it all, Valhalla is romance elevated. Sip cocktails at your private sky bar with jaw-dropping mountain views that stretch for miles. Soak in a clawfoot tub with breathtaking scenery right outside your window. Snuggle up for movie nights on the large screen TV. Fall asleep under the stars, wake up to misty mountain mornings. 💕 Add champagne, wine & chocolates to make it unforgettable. (upon request for an additional charge)

Clemson Games + Lake Keowee
Come stay at this new construction home in a Lake Keowee neighborhood, only 8 miles from Clemson and to Death Valley. Whether you're seeking convenient access to Clemson for college activities, such as move-in move out for students, game weekends, or to enjoy Lake Keowee this house is the perfect fit! This house offers plenty of amenities during your stay such as blackout curtains in all the bedrooms, a privacy fence in the backyard for barbecuing, and a ping-pong table in the garage! 

Waterfall Views, Lake Hartwell, Highland Architect
Come and enjoy nature with 100+ acres to roam. Architect James Fox designed this cantilevered cliffside home overlooking a beautiful waterfall. Feel like you are in the trees, in an area much as it was when inhabited by Cherokee Indians. Stream feeds into Lake Hartwell. In the summer months on the weekends and holidays kayaks, jet skis and small boats visit the falls. This property is in the foothills of the Appalachian Mountains. Please respect our pet policy, only service animals.

Modern & Cozy Cottage-12 min. from Clemson Uni.
Experience South Carolina from this new cottage in Seneca. It's 5 minutes from the Historic Ram Cat Alley with Live Outdoor music every Thursday Night (Apr.-Oct.) Shopping, Boutiques, Restaurants, Breweries, and Coffee Shops. It's only 12 minutes from Clemson University, and a short drive to Lake Keowee, Lake Jocassee, and Lake Hartwell. This area is home to numerous Waterfalls, Hiking Trails, and southern barbecue. If you want a quiet southern getaway, it's the place for you!

Hidden Lake Sanctuary
Recently remodeled and boasting 3000 sq ft, this home offers comfort and serenity. Tucked away in a peaceful cove feeding into Lake Keowee, it’s the perfect escape for nature lovers-especially kayakers. The property comes fully equipped with kayaks and paddle boards. Please note: Access to the dock involves a very steep descent, and the return hike can be challenging—best suited for active guests. Unwind in the private hot tub on the deck or gather around the cozy fire pit.

The Landing Spot
As seen on House Hunters!!!The Landing Spot is your Lake Keowee getaway—just a short walk to the marina with boat rentals, a lakeside restaurant, bar, and more. Close to public beaches, hiking, and downtown Seneca, yet tucked away under dark, starry skies. Game room, digital check-in, and room to relax. Clemson is just 20 minutes away, perfect for visits and game days. A laid-back space for families and friends to enjoy lake life and unwind.

The Cottage
Relax, recharge, and enjoy the quiet. Unwind on the front porch as the sun sets and nature comes alive with the peaceful sounds of evening. Spend time by the pond and cast a line for a simple, relaxing escape (fishing poles not provided). Private and serene, yet just 5 minutes to Walmart and Oconee Memorial Hospital—and only 13 miles to Clemson. The perfect blend of tranquility and convenience. Minimum age to book is 25 years of age.

Shady Rest
As you enter the screened in front porch you will instantly relax, experience a peaceful and quiet tree lined front yard. The house has plenty of shade and old oaks, built in 1935 has the charm of visiting great grandmother’s farm house without the wallpaper. Large side deck with grill, hot tub and plenty of shaded sitting. Side yard has a fire pit for evening campfires and roasting marshmallows. The house has an open floor plan.

Getaway on Lake Hartwell: Pontoon Rental, Clemson
Our 3 bedroom house is located on Lake Hartwell and is just a 15 min drive to Clemson University. You can enjoy access to the dock and beach which are a quick golf cart ride away. We have paddle boards on the dock and kayaks, coolers, bagged ice, fishing poles etc upon request. Off the back of the detached garage there’s a furnished screened-in deck with a grill that overlooks the end of the cove and fire pit below.

The Carriage House at South Townville
Stay in a charming loft-style carriage house in historic downtown Seneca. This two-bedroom space comfortably sleeps 4 and features a full kitchen, private bathroom, and convenient washer/dryer combo. Enjoy walkable access to local shops, restaurants, and coffee spots, or take a short drive to Lake Keowee for boating and views, or visit Clemson University for games and campus events. Perfect for a relaxing getaway.
Popular amenities for house rentals in Seneca
House rentals with a pool

Lakeside Retreat • Pet friendly • Fire Pit

Keowee Key Luxury Condo - Stunning Views!

Lakeside Retreat - 4BR/4BA Home

Casa Key

A+ Keowee Kustom!*NO Dock!

Golf view, lake access, 3 pools!

* Keowee Key* Lake* Fireplace*Golf*Tennis*Gym*

Cottage close to Clemson with private pool!
Weekly house rentals

Sweet Tea Retreats

Lakefront Mid-Century Dream Home / 3 mi to Clemson

Modern Home Near Keowee, Clemson, Walhalla

The Midpoint Manor

Lakefront Home w/Deep Water Dock 20 min to Clemson

Mountain Road Cottage

New! Charming 4/2.5 Modern Home in Clemson, SC

Lakefront Football Paradise in Seneca SC
Private house rentals

Pet-Friendly 5BR Getaway near Lake Keowee

The Yellow Quilt in Walhalla

The Black Brick

Lakefront+Near Clemson+Dock+Kayaks+Putting Green

No cleaning fee farmhouse lake keowee near Clemson

Lake House Retreat Near Clemson

Cozy Modern Home Close Clemson

Forest Hills Retreat
When is the best time to visit Seneca?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sept | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | $220 SGD | $259 SGD | $244 SGD | $195 SGD | $250 SGD | $215 SGD | $211 SGD | $304 SGD | $281 SGD | $251 SGD | $300 SGD | $233 SGD |
| Avg. temp | 6°C | 8°C | 12°C | 16°C | 21°C | 25°C | 27°C | 26°C | 23°C | 17°C | 11°C | 7°C |
Destinations to explore
- Nashville Holiday rentals
- Atlanta Holiday rentals
- Myrtle Beach Holiday rentals
- Charlotte Holiday rentals
- Gatlinburg Holiday rentals
- Savannah Holiday rentals
- Charleston Holiday rentals
- Pigeon Forge Holiday rentals
- Hilton Head Island Holiday rentals
- North Myrtle Beach Holiday rentals
- Louisville Holiday rentals
- Raleigh Holiday rentals
- Rentals with a washing machine and dryer Seneca
- Rentals with a firepit Seneca
- Lakehouse rentals Seneca
- Rentals with a patio Seneca
- Rentals with lake access Seneca
- Waterfront rentals Seneca
- Family-friendly rentals Seneca
- Pet-friendly rentals Seneca
- Cabin rentals Seneca
- Rentals with outdoor seating Seneca
- House rentals Oconee County
- House rentals South Carolina
- House rentals United States
- Clemson University
- Black Rock Mountain State Park
- Table Rock State Park
- Gorges State Park
- Tallulah Gorge State Park
- Helen Tubing & Waterpark
- Devils Fork State Park
- Bell Mountain
- DuPont State Forest
- Bon Secours Wellness Arena
- Unicoi State Park and Lodge
- Ski Sapphire Valley
- Fred W Symmes Chapel
- Chattooga Belle Farm
- Jump Off Rock
- Looking Glass Falls
- Dillard House Restaurant
- Fluor Field at the West End
- Anna Ruby Falls
- Jones Gap State Park
- Peace Center
- Falls Park On The Reedy
- Carl Sandburg Home National Historic Site
- Dry Falls





