Bed and breakfast holiday rentals in Upstate South Carolina

Find and book unique bed & breakfast rentals on Airbnb

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Popular amenities for bed & breakfast rentals in Upstate South Carolina

Family-friendly bed & breakfast rentals

Superhost
Hotel room in Clemson
5 out of 5 average rating, 7 reviews

Two private rooms with bathroom

LindsayRating, 5 stars19 months ago
Everything about our stay at Diana’s was perfect! Location, cleanliness, attentiveness and all the extras! She made us feel like family and truly cared about us having a nice and relaxing time while visiting! We will be returning guests, cannot say enough great things about this wonderful lady and her place! Go TIGERS!
Top guest favourite
Private room in Maggie Valley
4.98 out of 5 average rating, 124 reviews

Holly Tree Bed & Breakfast - Mountain View Room

BryanRating, 5 stars3 weeks ago
Judy is one of a kind host. I couldn’t ask for a kinder lady that was so easy to communicate with and made you feel at home from the start.And to cook you breakfast every morning you’re there. She reminds me of my mom . Me and my brothers have a saying about mom you could cook rocks and make them taste good .She is in that category.If you’re looking for a peaceful place to stay that has the comfort of home this is the place.And her place is super clean.I highly recommend it for your stay in Maggie Valley .
Top guest favourite
Private room in Jefferson
4.96 out of 5 average rating, 68 reviews

One Room - Sleeps 2 Guests Queen Bed on Small Farm

MikeRating, 5 stars10 months ago
I have been so blessed in my Air BNB experiences and John's farm was no exception. He was extremely friendly and his farm was beautiful. Goats , chickens, cows, and the greatest ,pot belly pig ever named "Charlotte" ........a hot tub, an amazing inground pool, piano, guitar, full access to a great kitchen for making meals... very comfortable and nice home......We enjoyed our short time there and will definitely be back.
Resort in Scaly Mountain

Blue Valley in the Lodge | Mtn. View | Fireplace

WallaceRating, 5 stars44 months ago
Public spaces were outstanding. Loved the library, a great place to unwind. Delicious breakfasts and the dining room was beautiful. We plan to go back.
Private room in Ashville
5 out of 5 average rating, 4 reviews

#8 Rose Room - OaklandCottage B&B

JavanRating, 5 stars1 week ago
Such a pleasure staying here! It was cozy, clean, and beautiful. Breakfast was delicious and they even went above and beyond accommodating our stringent dietary restrictions - something we were NOT expecting. Communication was friendly and helpful, and they did so much for us to help ensure our stay was pleasurable. Truly this place is run with love!
Hotel room in Tryon
4.91 out of 5 average rating, 55 reviews

GreenLife Inn at Mimosa Room 202

SueRating, 5 stars47 months ago
Oh my gosh! My friend and I had a girls' weekend in the Tryon area visiting the local wineries and we stayed at the Green Life Inn, and it was a great experience! Mary's special touches were amazing! There were snacks & water in the room, top-quality soaps and shampoo were provided, and the bed linens were AMAZING! To top it all off, Mary provided quite the spread of food for breakfast. Homemade (yummy) muffins, cheesy hashbrowns with sausage, hard-boiled eggs, yogurt, fruit, juice, coffee and much more! We will definitely stay there again! Thank you Mary for your hospitality!
Top guest favourite
Private room in Irmo
4.99 out of 5 average rating, 92 reviews

Lake Murray Retreat

MaryAnnRating, 5 stars1 month ago
Louise‘s place was wonderful. Very warm and inviting. Handpicked flowers awaited our arrival, along with fresh fruit, snacks, and coffee creamer! Always thankful for coffee creamer!Communication from check-in to check out was great. The house itself is spectacular. The lake view is great! The suite we stayed in was very roomy, and perfectly clean. Would definitely stay again.
Private room in Grover
5 out of 5 average rating, 4 reviews

Former White House Chefs home (Oceanicus Blue rm)

JeremyRating, 5 stars37 months ago
We thoroughly enjoyed our stay at the Inn of the Patriots! The breakfasts were amazing and one of a kind. The tours that Marti gives and the lore he covers are very fun. Also Marti's guidebook was very helpful for touring the area. It's an old home with lots of history. Our room was comfy and clean and we were well cared for.

Bed and breakfast rentals with breakfast

Private room in Spartanburg
4.76 out of 5 average rating, 25 reviews

Quiet Home, Gardens, Qn BR or Single, Kitchens

PatrickRating, 5 stars5 months ago
Loved it Linda was great made me feel at home. Felt like part of the family. Would recommend!
Private room in Waynesville
4.8 out of 5 average rating, 60 reviews

10.Grandview Lodge in the Great Smoky Mountains

LisaRating, 5 stars4 months ago
Very easy to find, host was present at check in, the bed was very comfortable, hot shower, cozy fireplace, yummy breakfast, very friendly staff!
Guest favourite
Private room in Waynesville
5 out of 5 average rating, 43 reviews

Green Room at Love Lane B & B, walk to Main St.

ZacharyRating, 5 stars13 months ago
Can’t possibly say enough good things about this spot. Both John and Debbie were incredible and I left feeling like I had made new friends. Already miss this place and can’t wait to come back next time. If you’re looking for somewhere in the area to stay this should absolutely be #1 on your list.
Private room in Clyde
5 out of 5 average rating, 14 reviews

Creekside Inn B&B - Country Suite

ShannonRating, 5 stars19 months ago
We had a wonderful stay at Creekside Inn B&B . Mike was there to great us soon as we arrived and gave us a tour of the entire inn . We felt right at home , Mike suggested several spots for dinner and his wife also had several options for us to try . The restaurant we picked was a great place and was one of their recommended spots . The space was warm and inviting with ample space and great views. We had a restful night and were very pleased with the wonderful breakfast served the next morning . We also meet a nice couple from Raleigh NC who were also enjoying their stay . We will definitely be back soon for another stay , super close to I-40 Easy access in and out
Private room in Wellford

Skunk Works Farms B&B

HelenRating, 5 stars2 months ago
Heather and her husband are great host and very friendly people. If you love being around animals and love the country life then there place is definitely for you. It made me feel back home. Gave off a good country vibe which I love bye the way .
Guest favourite
Private room in Sylva
4.98 out of 5 average rating, 57 reviews

Cabin Suite at the Dillsboro Inn

MaryRating, 5 stars5 months ago
Friendly host, luxury linens, and the most beautiful surroundings!! This place was awesome. My husband and I arrived late on Christmas night around 9pm. I mentioned to TJ how we weren’t able to find anywhere open to eat (because of Christmas) and TJ (the innkeeper) ended up making us 2 turkey sandwiches for dinner!! Talk about hospitality. We stayed in the Riverside Suite and the linens were AMAZING. I was not expecting that but the sheets were ultra soft as well as the towels and the mattress was so comfy. Literally checked the brand to buy the towels for my house. The hot tub is the perfect way to relax after hiking all day and our pup enjoyed every minute. I was grateful to get to chat with TJ and the story behind the inn and how he has put his heart in soul into that place. You can feel that spirit and love throughout the whole property. We will definitely be back!!
Private room in Greenville

Hummingbird - Pettigru Place Bed & Breakfast

KyleRating, 5 stars55 months ago
I can’t say enough nice words about Pettigru B&B. Lori is utmost, the most amazing and gracious hostess. She’s taken every detail into consideration when decorating and offers her guest a warm and hospitable place to stay. The breakfast was delicious, the gardens gorgeous. My husband and I cannot wait for our next visit. Xx, Shannon and Kyle Posey
Private room in Abbeville
5 out of 5 average rating, 4 reviews

HayGood Manor Bed & Breakfast - Rooms

Darryl & LeslieRating, 5 stars49 months ago
Haygood Manor is simply amazing! There is deep history and a sense of wonderment in every room. Selena is the ultimate host! Each room is warm and welcoming. Her home is within walking distance to Abbyville's town square where there a plenty of shops and restaurants to visit. We will definitely be back as there is no way you can take in all the Haygood Manor has to offer in one visit!

Bed and breakfast rentals with a patio

Private room in Pendleton

Suite 1 Bridal suite 1 King bed private bathroom.

SusanRating, 5 stars33 months ago
This was a great location to the Clemson Campus. So much better than the local motels. Our room was wonderful and really enjoyed the home cooked breakfast every morning. Will definitely stay here again while visiting Clemson.
Private room in Sylva

Near Casino. Spare bedroom and bath.

nateRating, 5 stars25 months ago
Patricia & her husband were incredibly hospitable, making me feel right at home. The bedroom was cozy and comfortable, ensuring a restful night's sleep. What's more, the affordability of this accommodation was impressive, offering great value for the price. I highly recommend this delightful Airbnb property for a memorable stay that won't break the bank.
Guest favourite
Private room in Greenville
4.97 out of 5 average rating, 86 reviews

B & B/Downtown/Furman/BJU/3

KathleenRating, 5 stars1 month ago
This is by far one of my favorite listings I have stayed at! As soon as you walk in the door you feel at home! You can truly tell how much love and work went into the space and the shared home is beautiful! My room was incredibly clean and had not only the sweetest goodies but also had local magazines, local recs, and of course helpful house instructions! The amenities were a huge bonus: great breakfast selection, laundry available, and the living room had a fun selection of games! The house also had great spots to hang out outside and enjoy the beautiful weather! Communication with Lindsy was always quick, clear, and kind!! I felt in safe hands with her and extremely taken care of from a guest perspective! I would highly recommend this beautiful home to anyone looking to stay in the Greenville area :)
Guest favourite
Private room in Etowah
5 out of 5 average rating, 15 reviews

Bed & Breakfast No cleaning fee

KarenRating, 5 stars19 months ago
Elizabeth's place was exactly how it was described on the website. She even greeted us outside, when we arrived, and made us feel right at home! This B&B is close to the Dupont Forest and the Blue Ridge Parkway which was close to our day trip hiking destinations. Downtown Asheville and Brevard are also close by so there's plenty to do. Or if you want to sit and relax on their back porch and read a book that option is also available. We were so comfortable in their home it felt like visiting a long lost friend. Both Jim and Elizabeth had great stories to tell and also gave us a mini concert in their living room. Her weekend breakfasts were outstanding and she's a fantastic cook! I would highly recommend this place to anyone who wants to stay in this area. We will definitely be back.
Superhost
Private room in Greenville

B & B/Downtown/Bon Secour/Furman/BJU

QiyongRating, 5 stars13 months ago
Very attentive and thoughtful, they have everything you need including coffee, snacks, chocolate, popcorn, etc.
Private room in Belton
4.62 out of 5 average rating, 13 reviews

King Suite in Historic Bed and Breakfast

BrandonRating, 5 stars19 months ago
it was great for peaceful night in. The property was beautiful
Top guest favourite
Private room in Greenville
4.96 out of 5 average rating, 163 reviews

B & B/Downtown/Furman/BJU/2

SarahRating, 5 stars1 week ago
We were just coming in for a night before joining a staff retreat and didn’t want to pay for an entire house to ourselves for one night, so we decided to rent a room here. Extremely affordable and really nice home. The little breakfast in the morning was great. Lindsy was extremely helpful and even let us do a little later checkout so we could have a slow morning. Others were very polite and quiet. And there were plenty of things around that we wanted like good coffee shops and even a state park for a nice little walk/hike. Bed was very comfortable which isn’t always the case but huge for our backs. We loved it and will definitely do it again if the situation is similar in the future. Highly recommend!
Private room in Pelzer

Charming Pelzer Historic Inn

Destinations to explore