
House holiday rentals in Upstate South Carolina
Find and book unique houses on Airbnb
Top-rated house rentals in Upstate South Carolina
Guests agree: these houses are highly rated for location, cleanliness and more.

Modern Private cabin | WiFi| | Hot Tub | Fire Pit
Stunning villa, perched atop a mountain, surrounded completely by other mountains. An expansive deck was designed and furnished intentionally to allow for guests to enjoy the LONG RANGE VIEWS from various angles. This Frank Lloyd Wright inspired villa takes the "city vibe" into the woods, with large windows bringing in light and showcasing the beautiful natural setting. Interior features are open, uncluttered, and incredibly comfortable, with quality at the forefront of our minds in this space.

Atrium House - Spa Retreat
Come unwind and breathe at our couples mountain spa retreat. Atrium House has been designed to feel open to the lovely mountain surroundings yet let you relax in privacy. Our outdoor therapy hot tub, indoor/outdoor gas fireplace, and spacious two-person, walk-in shower make for a getaway so tranquil, you may never make it in to nearby Asheville! We're out in the country but just over a 15-minute drive from downtown Asheville, Biltmore, Hendersonville, Asheville Airport, and dozens of breweries.

Modern Wooded Retreat
Come enjoy this modern, 1.6 acre retreat! Relax with the whole family in a place you'll never want to leave. Located 5 min. to downtown TR and less than 20 min to downtown Greenville! Roast marshmallows by the firepit, play yard jenga, connect 4 and cornhole in the fully fenced, dog friendly back yard. Close to the swamp rabbit trail, and centrally located to lakes, hiking, fishing and exciting nightlife. Let us host you, while you explore everything Greenville and Travelers Rest have to offer.

Shipyard 2.0 | Hot Tub, Waterfall, Fire + Hammock!
BNB Breeze Presents: The Green Creek Shipyard 2.0! Experience this unique container home in the heart of the Foothills! Designed and built by 3 siblings, after much hard work and thoughtful consideration went into creating this magnificent retreat! This stunning home includes: ★ Hot Tub! ★ Beautiful Custom-Built Waterfall with a daybed. ★ A Wrap-around Deck ★ Stunning Fire Pit with Adirondack Chairs + String Lights! ★ Sunk-in Hammock + Swings ★ Webber Grill ★ Custom Corn Hole Boards + More!

Waterfall Views, Lake Hartwell, Highland Architect
Come and enjoy nature with 100+ acres to roam. Paths for long walks. Architect James Fox designed this cliffside home overlooking a beautiful waterfall. Feel like you are in the trees, in an area much as it was when inhabited by Cherokee Indians. Stream feeds into Lake Hartwell. In the summer months on the weekends and holidays kayaks, jet skis and small boats visit the falls. This property is in the foothills of the Appalachian Mountains. Please respect our pet policy, only service animals.

Greenville GEM Luxurious Retreat in Prime Location
Beautifully renovated 3 beds, 2 baths haven! This gem is a tranquil & stylish retreat, blending modern & cozy charm. Spacious bedrooms, each with plush bedding and storage. Two Bathrooms with soaking tub and a spacious walk-in shower. Cozy living room with a fireplace, TV, and comfy seating. Fully equipped kitchen, Wi-Fi, Private deck and gazebo, fenced yard. Close to the city's best attractions, dining, and entertainment options. This is the perfect home base for your Greenville adventures.

Cabin I Private hiking trails | Hot Tub I Sauna
Welcome to your private mountain escape in Lake Toxaway, NC! This 1-bedroom, 2-bathroom cabin is a one-of-a-kind retreat, offering breathtaking sunset views, a peaceful wooded setting, and unique architectural details. Unwind in the hot tub under the stars, relax in the sauna, challenge your partner to air hockey, or cozy up by the fire pit—all while enjoying the beauty of nature. Plus, enjoy exclusive access to 3 miles of private hiking trails, perfect for exploring the great outdoors!

Orchard Hill Vintage Cottage
Come enjoy this magnificent view in Saluda! Relax in the swings or sit on the porch and enjoy the peacefulness. The fire pit under the stars is so Saludacrous! Our cozy cottage is just steps from Judds Peak and 2 miles from downtown, where there is always food and fun! The Gorge Zipline is located in our quaint little town and the Green River has hiking, tubing, kayaking, white water rafting, rock climbing! The towns of Hendersonville, Flat Rock and Asheville are just minutes away.

Cozy Treehouse
Situated at the back of a wooded 2 acre lot, only 10 minutes from downtown Greenville, this is a little oasis in the city! While most treehouses take you on a "roughing it" adventure, Cozy Treehouse is the glamping version of treehouses, boasting 9' ceilings, 1.5 baths, 3 LED TV's and many outdoor living options. If you are looking for a unique getaway just minutes from one of the top growing cities in the south, Cozy Treehouse is the perfect destination for you.

Million Dollar View’s | Chef Kitchen | Luxury bath
Cloud 9 isn’t just a place to stay — it’s a place to feel. Elegant. Refined. Rooted in nature. Thoughtfully designed and tucked into the mountains, this soulful retreat offers stillness, beauty, and intention in every detail. It doesn’t compete with the land — it whispers into it. Here, quiet becomes the ultimate amenity. A place that feels like home — and a dream — all at once. Come experience the kind of calm that stays with you. Book your stay at Cloud 9

Walk-to-Downtown Retreat | Creekside + Hot Tub
Perfect get away, this 820-sq-ft creekside cabin blends 1950s charm with modern comforts—two queen bedrooms, a bright kitchen, and a relaxed living room. Step onto the back porch or creekside patio for slow mornings and sunset chats, then wander 5 minutes to downtown Clayton for dinner, craft drinks, and dessert. Afterward, slip into the hot tub under the stars. Trails, waterfalls, whitewater, and Black Rock Mountain vistas are minutes away.

The Cottage
Come relax and refresh in peaceful surroundings. Relax and unwind on the front porch. Experience tranquility as the sun sets and the frogs start croaking. You are welcome to cast a line in the pond to try your skill at fishing. Fishing poles are not provided. The cottage is private but still has convenience of Walmart and Oconee Memorial Hospital within a 5 minute drive. We are 13 miles from Clemson.
Popular amenities for house rentals in Upstate South Carolina
House rentals with a pool

Lakeside Family & Dog Retreat Awaits! DWC

Keowee Key Luxury Condo - Stunning Views!

Aframe Amazing Views Hot Tub Dog & Family Friendly

HOT TUB Sleeps 11 Gameroom Cozy Getaway

Pet + Family Friendly 4BR Pool House Near Furman

Shalom House with Pool near DT Greer SC

Wonderful mountain cottage with amazing view!

A quiet place in the country
Weekly house rentals

Willow Oak Retreat // Comfy beds & Large backyard!

The Wright Place! 25/min DT G-Ville. Pool/Hottub.

Mountain Villa 15min from Downtown Greenville

The Dogwoods Middle at Vineyard Gap

Secluded Private Retreat

Modern Home Near I-85, Pets Welcome, Fast WiFi

House 564

West End Cottage
Private house rentals

Palmetto Trailside Retreat

Welcome to River House

Cozy home in downtown TR

Modern Mountain Stream Overlook

Mazie’s Place

Cozy Country Cottage edge of town.

The Little Queen

Sunset Cottage -Waterfront with Kayaks
Destinations to explore
- Western North Carolina Holiday rentals
- Nashville Holiday rentals
- Atlanta Holiday rentals
- Myrtle Beach Holiday rentals
- Gatlinburg Holiday rentals
- Charleston Holiday rentals
- Charlotte Holiday rentals
- Pigeon Forge Holiday rentals
- Cape Fear River Holiday rentals
- Savannah Holiday rentals
- Hilton Head Island Holiday rentals
- Asheville Holiday rentals
- Fitness-friendly rentals Upstate South Carolina
- Serviced apartment rentals Upstate South Carolina
- Rentals with pools Upstate South Carolina
- Cottage rentals Upstate South Carolina
- Townhouse rentals Upstate South Carolina
- Apartment rentals Upstate South Carolina
- Boutique hotels Upstate South Carolina
- Treehouse rentals Upstate South Carolina
- Tiny house rentals Upstate South Carolina
- Resort rentals Upstate South Carolina
- Ski-in/ski-out rentals Upstate South Carolina
- Bed and breakfasts Upstate South Carolina
- Pet-friendly rentals Upstate South Carolina
- Guest house rentals Upstate South Carolina
- Rentals with a fireplace Upstate South Carolina
- Rentals with a firepit Upstate South Carolina
- Private suite rentals Upstate South Carolina
- Waterfront rentals Upstate South Carolina
- Smoking-friendly rentals Upstate South Carolina
- Holiday home rentals Upstate South Carolina
- Chalet rentals Upstate South Carolina
- Rentals with a patio Upstate South Carolina
- Family-friendly rentals Upstate South Carolina
- Villa rentals Upstate South Carolina
- Rentals with an accessible-height toilet Upstate South Carolina
- Rentals with a sauna Upstate South Carolina
- Cabin rentals Upstate South Carolina
- Loft rentals Upstate South Carolina
- Rentals with an EV charger Upstate South Carolina
- Hotel rooms Upstate South Carolina
- Barn rentals Upstate South Carolina
- Rentals with beach access Upstate South Carolina
- Rentals with a cinema Upstate South Carolina
- Rentals with lake access Upstate South Carolina
- Campsite rentals Upstate South Carolina
- Rentals with a hot tub Upstate South Carolina
- Rentals with a kayak Upstate South Carolina
- Rentals with outdoor seating Upstate South Carolina
- Nature eco lodge rentals Upstate South Carolina
- Flat rentals Upstate South Carolina
- Farm stay rentals Upstate South Carolina
- Motorhome rentals Upstate South Carolina
- Tent rentals Upstate South Carolina
- Rentals with a washing machine and dryer Upstate South Carolina
- Rentals with breakfast Upstate South Carolina
- Beachfront rentals Upstate South Carolina
- House rentals South Carolina
- House rentals United States
- Blue Ridge Parkway
- The North Carolina Arboretum
- Gorges State Park
- Table Rock State Park
- Chimney Rock State Park
- Ski Sapphire Valley
- Lake Lure Beach and Water Park
- Jump Off Rock
- Tryon International Equestrian Center
- Wade Hampton Golf Club
- Victoria Valley Vineyards
- Discovery Island
- Haas Family Golf
- Carl Sandburg Home National Historic Site
- Saint Paul Mountain Vineyards
- City Scape Winery
- Burntshirt Vineyards
- Overmountain Vineyards
- Wellborn Winery
- Russian Chapel Hills Winery
- Things to do Upstate South Carolina
- Things to do South Carolina
- Tours South Carolina
- Sports activities South Carolina
- Food and drink South Carolina
- Sightseeing South Carolina
- Art and culture South Carolina
- Entertainment South Carolina
- Nature and outdoors South Carolina
- Things to do United States
- Sightseeing United States
- Art and culture United States
- Food and drink United States
- Wellness United States
- Entertainment United States
- Nature and outdoors United States
- Tours United States
- Sports activities United States




