
House holiday rentals in Upstate South Carolina
Find and book unique houses on Airbnb
Top-rated house rentals in Upstate South Carolina
Guests agree: these houses are highly rated for location, cleanliness and more.

Location-Explore-Relax-Work! *Serene* Forest Views
Take in serene nature views while being central to everything Greenville has to offer. Whether here for work or vacation, enjoy convenience and peaceful surroundings. โ 15 min to Paris Mountain State Park โ hiking, biking, and distance views โ 17 min to Downtown Greenville โ restaurants, shops, and Falls Park โ 12 min to Swamp Rabbit Cafรฉ & Grocery โ local coffee, baked goods, and market โ 5โ10 min to grocery stores and gas stations Relaxation, work or explore? We would love to host you here.

NEW mountain cottage between Dupont and Pisgah!!
Getaway and enjoy this New fully furnished cottage style home complete with new queen beds, hardwood floors on a beautiful private .50 acre lot. Listen to the small waterfall and catch a peak of the local deer sipping from our backyard stream as you enjoy your morning cup of joe on the balcony. Then take a ride into downtown Brevard to hit the local eats and shops. Pisgah Forest is centrally located to Dupont State Forest and Pisgah National Forest, Downtown Brevard and a variety of breweries.

Greenville GEM Luxurious Retreat in Prime Location
Beautifully renovated 3 beds, 2 baths haven! This gem is a tranquil & stylish retreat, blending modern & cozy charm. Spacious bedrooms, each with plush bedding and storage. Two Bathrooms with soaking tub and a spacious walk-in shower. Cozy living room with a fireplace, TV, and comfy seating. ย Fully equipped kitchen, Wi-Fi, Private deck and gazebo, fenced yard. Close to the city's best attractions, dining, and entertainment options. This is the perfect home base for your Greenville adventures.

Cabin I Private hiking trails | Hot Tub I Sauna
Welcome to your private mountain escape in Lake Toxaway, NC! This 1-bedroom, 2-bathroom cabin is a one-of-a-kind retreat, offering breathtaking sunset views, a peaceful wooded setting, and unique architectural details. Unwind in the hot tub under the stars, relax in the sauna, challenge your partner to air hockey, or cozy up by the fire pitโall while enjoying the beauty of nature. Plus, enjoy exclusive access to 3 miles of private hiking trails, perfect for exploring the great outdoors!

The Extra House
We have a comfortable Extra House we call it. Extra cozy extra cute Extra House. The house is right on the Tallulah River in Towns County. There is fishing/swimming hole about 100 ' up river and a waterfall up a trail behind the Big House about a 30 minute hike up and back. Longer if you jump in the falls. Trout fishing out the door and 6 miles of fishing along the main road. We have a 250' zipline into a swiming pond or get off before the water. Lots of hiking trails and waterfalls.

Orchard Hill Vintage Cottage
Come enjoy this magnificent view in Saluda! Relax in the swings or sit on the porch and enjoy the peacefulness. The fire pit under the stars is so Saludacrous! Our cozy cottage is just steps from Judds Peak and 2 miles from downtown, where there is always food and fun! The Gorge Zipline is located in our quaint little town and the Green River has hiking, tubing, kayaking, white water rafting, rock climbing! The towns of Hendersonville, Flat Rock and Asheville are just minutes away.

Waterfall Views, Lake Hartwell, Highland Architect
Come and enjoy nature with 100+ acres to roam. Architect James Fox designed this cantilevered cliffside home overlooking a beautiful waterfall. Feel like you are in the trees, in an area much as it was when inhabited by Cherokee Indians. Stream feeds into Lake Hartwell. In the summer months on the weekends and holidays kayaks, jet skis and small boats visit the falls. This property is in the foothills of the Appalachian Mountains. Please respect our pet policy, only service animals.

Cozy Treehouse
Situated at the back of a wooded 2 acre lot, only 10 minutes from downtown Greenville, this is a little oasis in the city! While most treehouses take you on a "roughing it" adventure, Cozy Treehouse is the glamping version of treehouses, boasting 9' ceilings, 1.5 baths, 3 LED TV's and many outdoor living options. If you are looking for a unique getaway just minutes from one of the top growing cities in the south, Cozy Treehouse is the perfect destination for you.

Lanaโs Cottage
Welcome to our cozy cottage in historic Abbeville. We are in a quiet and family friendly neighborhood. This home comfortably sleeps six adults. The kitchen is fully stocked and is perfect for making a cup of coffee to cooking a full meal! Thereโs a smart TV with fast internet to be able to access your favorite streaming service. We are 1 mile from groceries and your choice of local restaurants. We are delighted to host you in our home.

Hidden Retreat
4 private acres just off Hwy 11. HIKE - connector to the Palmetto trail and Table Rock State Park. BIKE - popular biking routes; Hwy 11, Hwy 288 and Hwy 178 + Doodle & Swamp Rabbit Trail. GOLF - 1 course 5 minutes away several others nearby. WATERFALLS - including the highest in the east. MOUNTAIN LAKES - 2 of the best, Jocassee & Keowee. HIDDEN RETREAT - close to many outdoor adventures. Up to 6 guests.

The Cottage
Come relax and refresh in peaceful surroundings. Relax and unwind on the front porch. Experience tranquility as the sun sets and the frogs start croaking. You are welcome to cast a line in the pond to try your skill at fishing. Fishing poles are not provided. The cottage is private but still has convenience of Walmart and Oconee Memorial Hospital within a 5 minute drive. We are 13 miles from Clemson.

Wow! Mountain Home on 30 acres
This nearly new home enjoys a beautiful mountain view and sits in the middle of 30 private acres within the city limits. Enjoy the delights of the beautiful downtown, scenic mountain views from the relaxed seating on the front porch, or catch some awesome sunsets from the back deck with fire-pit and propane grill. Pets are not allowed on this listing, due to allergies. Thank you!
Popular amenities for house rentals in Upstate South Carolina
House rentals with a pool

Pet-Friendly 4BR: Pool, Screen Porch, Fenced Yard

Pool with Mountain Views | Hot Tub & Gameroom!

Keowee Key Luxury Condo - Stunning Views!

Estate-Like Retreat/ Walk to Town /Hot Tub & Pool

Wonderful mountain cottage with amazing view!

Shalom House with Pool near DT Greer SC

Spacious 3 BR house with private backyard.

Near Downtown Greenville + Swamp Rabbit Trail
Weekly house rentals

Cozy Retreat in the Treesโข4.8 to HighlandsโขNo Fees

Cedar Place 2Bath~Venues~FastWi-Fi~

Kingfisher's Roost - Waterfront Cabin/Private Dock

Bobber Bungalow *level lot*fire pit*kayak*canoe

LONG Range VIEWS! Modern/Chic, Close DT Hendo Fun

Welcome to River House

Valhalla Sky Suite at Hisaw Gap Romantic Retreat

The Dogwoods Upper at Vineyard Gap
Private house rentals

Sunset Watch- Lake Greenwood

Modern Home Near Keowee, Clemson-Boat Rent Option

Calhoun Cottage

The Wren at Flat Mountain Farm

Mountains to Sea A-Frame

Beautiful Home - Blue Ridge, NGU, Travelers Rest

Cozy Cottage in Travelers Rest

Lakefront Escape w/ Private Dock
Destinations to explore
- Augustaย Holiday rentals
- Western North Carolinaย Holiday rentals
- Nashvilleย Holiday rentals
- Atlantaย Holiday rentals
- Myrtle Beachย Holiday rentals
- Charlestonย Holiday rentals
- Gatlinburgย Holiday rentals
- Charlotteย Holiday rentals
- Hilton Head Islandย Holiday rentals
- Savannahย Holiday rentals
- Cape Fear Riverย Holiday rentals
- Pigeon Forgeย Holiday rentals
- Private suite rentalsย Upstate South Carolina
- Waterfront rentalsย Upstate South Carolina
- Chalet rentalsย Upstate South Carolina
- Rentals with lake accessย Upstate South Carolina
- Rentals with a patioย Upstate South Carolina
- Rentals with a firepitย Upstate South Carolina
- Rentals with a washing machine and dryerย Upstate South Carolina
- Family-friendly rentalsย Upstate South Carolina
- Townhouse rentalsย Upstate South Carolina
- Nature eco lodge rentalsย Upstate South Carolina
- Serviced apartment rentalsย Upstate South Carolina
- Farm stay rentalsย Upstate South Carolina
- Motorhome rentalsย Upstate South Carolina
- Rentals with a kayakย Upstate South Carolina
- Rentals with breakfastย Upstate South Carolina
- Hotel roomsย Upstate South Carolina
- Tiny house rentalsย Upstate South Carolina
- Rentals with a saunaย Upstate South Carolina
- Rentals with beach accessย Upstate South Carolina
- Villa rentalsย Upstate South Carolina
- Treehouse rentalsย Upstate South Carolina
- Boutique hotelsย Upstate South Carolina
- Rentals with poolsย Upstate South Carolina
- Rentals with a hot tubย Upstate South Carolina
- Rentals with outdoor seatingย Upstate South Carolina
- Rentals with an EV chargerย Upstate South Carolina
- Guest house rentalsย Upstate South Carolina
- Cabin rentalsย Upstate South Carolina
- Loft rentalsย Upstate South Carolina
- Beachfront rentalsย Upstate South Carolina
- Fitness-friendly rentalsย Upstate South Carolina
- Rentals with an accessible-height toiletย Upstate South Carolina
- Campsite rentalsย Upstate South Carolina
- Rentals with a fireplaceย Upstate South Carolina
- Tent rentalsย Upstate South Carolina
- Flat rentalsย Upstate South Carolina
- Holiday home rentalsย Upstate South Carolina
- Bed and breakfastsย Upstate South Carolina
- Apartment rentalsย Upstate South Carolina
- Barn rentalsย Upstate South Carolina
- Smoking-friendly rentalsย Upstate South Carolina
- Resort rentalsย Upstate South Carolina
- Rentals with a cinemaย Upstate South Carolina
- Cottage rentalsย Upstate South Carolina
- Pet-friendly rentalsย Upstate South Carolina
- House rentalsย South Carolina
- House rentalsย United States
- Blue Ridge Parkway
- The North Carolina Arboretum
- Gorges State Park
- Chimney Rock State Park
- Ski Sapphire Valley
- Table Rock State Park
- Lake Lure Beach and Water Park
- Clemson University
- Jump Off Rock
- Tryon International Equestrian Center
- Bon Secours Wellness Arena
- Saint Paul Mountain Vineyards
- Carl Sandburg Home National Historic Site
- Burntshirt Vineyards
- Overmountain Vineyards
- DuPont State Forest
- Jones Gap State Park
- Falls Park On The Reedy
- Peace Center
- Fred W Symmes Chapel
- Devils Fork State Park
- Paris Mountain State Park
- Looking Glass Falls
- Furman University
- Things to doย Upstate South Carolina
- Things to doย South Carolina
- Toursย South Carolina
- Sports activitiesย South Carolina
- Art and cultureย South Carolina
- Food and drinkย South Carolina
- Nature and outdoorsย South Carolina
- Entertainmentย South Carolina
- Sightseeingย South Carolina
- Things to doย United States
- Toursย United States
- Sightseeingย United States
- Entertainmentย United States
- Food and drinkย United States
- Nature and outdoorsย United States
- Sports activitiesย United States
- Art and cultureย United States
- Wellnessย United States




