
Holiday home rentals in Upstate South Carolina
Find and book unique holiday home rentals on Airbnb
Top-rated holiday home rentals in Upstate South Carolina
Guests agree: these holiday home rentals are highly rated for location, cleanliness and more.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for holiday home rentals in Upstate South Carolina
Family-friendly holiday home rentals

Lake House and Dock Upscale and Immaculate

Lakefront Hartwell Home w/NEW Dock + NEW Fire Pit

Wake surrounded by views of the beautiful Blue Ridge Mountains in this lovely 1 bedroom vacation home.

Mountain Retreat - All New - Intown Waynesville NC

City Dream 2BR 2BA w Patio & Walk the Heart of GVL

Sandy Plains Fountain Home | King Bed | 3 MI TIEC

Trout Stream Resort Home & Guest Cabin/Pavilion

Nantahala River 2BR - Bear Cave Boat Parade
Holiday home rentals with a patio

Cozy Lake Hartwell Home 25 Minutes from Clemson

Studio in the heart of Greenville

Clemson/Anderson Lake Hartwell

PILOT COVE 1 BR - Modern Luxury w/ Nature!

Sunset Retreat - Big Deck, Mountain & Lake Views!!

Unique Lakefront Property Ideal for Multifamily or Large Family Stays

“forget the world” NC mountains

Fully furnished newly renovated 1b/1b Mtn Townhome
Holiday home rentals with a washing machine and dryer

Secluded mountain getaway near Blue Ridge Parkway

Lake Murray- Big Water Views, Dock, & Boat Ramp

Wright House Retreat

Eagle's Nest

Stunning Mtn Views in Western NC W/new hot tub

Rocky Ridge Base Camp @ DuPont - Bike from House!

Lakefront 4BR with dock - Check out our reviews!

Brookside at Beech Haven Suite 1 & 2 combined
Destinations to explore
- Western North Carolina Holiday rentals
- Nashville Holiday rentals
- Atlanta Holiday rentals
- Myrtle Beach Holiday rentals
- Charleston Holiday rentals
- Gatlinburg Holiday rentals
- Charlotte Holiday rentals
- Hilton Head Island Holiday rentals
- Savannah Holiday rentals
- Pigeon Forge Holiday rentals
- Cape Fear River Holiday rentals
- North Myrtle Beach Holiday rentals
- Rentals with a sauna Upstate South Carolina
- Townhouse rentals Upstate South Carolina
- Tiny house rentals Upstate South Carolina
- Cabin rentals Upstate South Carolina
- Loft rentals Upstate South Carolina
- Hotel rentals Upstate South Carolina
- Villa rentals Upstate South Carolina
- Serviced apartment rentals Upstate South Carolina
- Beachfront rentals Upstate South Carolina
- Nature eco lodge rentals Upstate South Carolina
- Rentals with a cinema Upstate South Carolina
- Rentals with pools Upstate South Carolina
- Rentals with a kayak Upstate South Carolina
- Rentals with an accessible-height toilet Upstate South Carolina
- Bed and breakfasts Upstate South Carolina
- Chalet rentals Upstate South Carolina
- Family-friendly rentals Upstate South Carolina
- Smoking-friendly rentals Upstate South Carolina
- Apartment rentals Upstate South Carolina
- Rentals with breakfast Upstate South Carolina
- Rentals with a hot tub Upstate South Carolina
- Private suite rentals Upstate South Carolina
- Waterfront rentals Upstate South Carolina
- Rentals with lake access Upstate South Carolina
- Barn rentals Upstate South Carolina
- Rentals with a washing machine and dryer Upstate South Carolina
- Rentals with a patio Upstate South Carolina
- Flat rentals Upstate South Carolina
- Fitness-friendly rentals Upstate South Carolina
- Cottage rentals Upstate South Carolina
- House rentals Upstate South Carolina
- Farm stay rentals Upstate South Carolina
- Rentals with a fireplace Upstate South Carolina
- Rentals with outdoor seating Upstate South Carolina
- Rentals with a firepit Upstate South Carolina
- Guest house rentals Upstate South Carolina
- Treehouse rentals Upstate South Carolina
- Rentals with an EV charger Upstate South Carolina
- Rentals with beach access Upstate South Carolina
- Pet-friendly rentals Upstate South Carolina
- Resort rentals Upstate South Carolina
- Holiday home rentals United States
- Blue Ridge Parkway
- Gorges State Park
- Table Rock State Park
- Chimney Rock State Park
- The North Carolina Arboretum
- Tryon International Equestrian Center
- Ski Sapphire Valley
- Lake Lure Beach and Water Park
- Jump Off Rock
- Wade Hampton Golf Club
- Victoria Valley Vineyards
- Haas Family Golf
- Carl Sandburg Home National Historic Site
- Discovery Island
- Overmountain Vineyards
- Wellborn Winery
- Burntshirt Vineyards
- Saint Paul Mountain Vineyards
- City Scape Winery
- Russian Chapel Hills Winery