
Guest house holiday rentals in Upstate South Carolina
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Top-rated guest house rentals in Upstate South Carolina
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Scenic Loft in the Woods
Come relax for a getaway in our elegant guest loft! Located near the end of a quiet road with lots of wide open fields and beautiful tree lines! Our loft features a cute kitchenette, plenty of closet space, TV(YoutubeTV & Roku), an extremely comfortable bed! The loft is kept very clean and neat and will be stocked with all the essentials. Access to a beautiful 33' above ground pool! We are conveniently located about 5 miles from downtown Abbeville, and only a 10 minute drive to Erskine/Due West!

The Cottage in Spartanburg
This charming & private studio cottage is located in Spartanburg's downtown historic district Hampton Heights. Guests will find a comfortable foam mattress sofa bed (no bars or springs), full bathroom, closet, & complete kitchen amenities. Located less than a mile from restaurants, bars, m-league ball park & shops of Downtown Spartanburg, and close to Converse Univ., VCOM, and Wofford College, this cozy studio cottage is the perfect place to rest your head after a busy day visiting the Upstate.

Historic 19th Century Cabin/Guest House
This 19th century cabin is your perfect cozy getaway. This guest house is located on a 3.5 acre property, secluded from the historic neighborhood, though it's just 3 miles from downtown Greenville and the Bon Secours Wellness Arena. Less than a mile to the Swamp Rabbit Trail, this cottage is perfect for jaunts to downtown Greenville, Furman University, Paris Mountain, Travelers Rest and Unity Park! Micro weddings and events are available upon request and approval with applicable fees applied.

Modern Cabin Retreat w/ Sauna
This space was designed with love and care and the hope that all who stay here feel relaxed and connected to nature. We recently added a cedar barrel sauna that heats up quickly and is user friendly. Often we don’t see guests but I’m always available for questions and recommendations. We live "next door" on the same property with our two young sons. The cabin is located in a neighborhood, so while it hopefully feels removed from any hustle and bustle, there is access to many conveniences.

The Cottage at Old Oaks Farm
Built in the early 1900's, this serene cottage is located approximately one mile from Furman University at the base of Paris Mt. It has been lovingly improved, but the floors are a bit slanted and no corner is exactly square. Located in a neighborhood on a five acre farm, it consists of three large rooms, comfortably furnished and lots of natural light. The cottage is convenient to downtown Greenville(5 miles),Travelers Rest, Furman, and the Swamp Rabbit Trail. No pet fee or cleaning fee.

Newly renovated guesthouse!
Relax at the MartInn, a newly renovated guesthouse only 20 minutes from downtown Athens, Ga. This one bedroom guesthouse is situated on a peaceful, wooded lot. Enjoy a cup of coffee on the deck, and then scramble some farm fresh eggs provided by the host’s chickens. The guesthouse is within 10-15 minutes of the Firefly Bike Trail, the North Oconee River Greenway, and Watson Milll Bridge State Park. Also nearby is the Broad River Outpost to rent kayaks for a float down the Broad River.

Wolf Lake Escape - lake & mountain retreat
Beautiful secluded setting on Wolf Lake. Private studio apartment with full kitchen and bath. Stunning lake view and full lake access with use of kayaks, canoe and dock in the adjacent cove. Private patio with fire pit and grill. Paradise Falls trailhead 1 mile away. Close to Panthertown Valley Backcountry Area with multiple trails and waterfalls. 45 minutes from Brevard, Sylva and Cashiers, NC. Easy drive to Asheville and Biltmore House. Onsite parking. Well behaved pets welcome

Mountain Edge Loft
Private loft apartment on 25 wooded acres, sits separate from main farm house. Private deck overlooking the woods. Everything you need for a cozy stay. Located on the edge of the Blue Ridge Escarpment with lakes Jocassee and Keowee just a few miles away. Numerous state parks, hiking, biking , waterfalls and kayaking or just peace and quiet. We are a sustainable homestead with an organic garden, chickens ,quail, dogs and cats. Our water comes from a natural spring.

Foothills Favorite
Custom designed 1 bedroom suite in the Lake Bowen/Landrum/Inman area. Comfortable yet sleek space tucked above a semi-detached garage; private entry & stairway to suite. Private deck overlooks green spaces, wooded area & Lake Bowen (best views late fall and winter). Enjoy mountain views at nearby Lake Bowen park, local wineries, and scenic highways. Minutes from Landrum & Tryon & Equestrian Center.

Shou-Sugi-Ban Retreat on the Saluda River
The Shou-Sugi-Ban Guest House is 5 miles from Greenville city center and West Greenville, yet you'll feel like you've escaped it all with the rush of the river and surrounding trees. This cozy, custom space has a king-size bed, and two sets of French doors leading out to a private deck. No matter where you are in the space, you'll have views of the 700 ft of Saluda river frontage.

Sally's Cottage
Couples retreat located 6 miles from downtown Greenville and the Swamp Rabbit Trail in a comfortable country setting. Wake up to a beautiful woods view through a large bay window and wildlife that surrounds the cottage (deer, birds and squirrels). Experience the beauty of the country in the city! Enjoy the eclectic collection of art and design in this cute little cottage.

Cozy Pet-Friendly Home | Near Greenville & I-85
You’ll love staying here because it’s the perfect mix of comfort, privacy, and charm. Whether you’re relaxing by the fire pit, enjoying the peaceful outdoor space, or unwinding inside with all the comforts of home, this cozy retreat offers everything you need for a relaxing and memorable stay. Plus, it’s pet-friendly and located in a quiet neighborhood close to everything!
Popular amenities for guest house rentals in Upstate South Carolina
Family-friendly guest house rentals

The Nest; private tiny home @Reblooming Rose

Tamarca Hollow, A Nature Retreat

Bungalow on a 3 acre mini farm

Private Suite in Downtown Simpsonville

Cozy Cottage - 5 miles from TIEC

Home on the farm

Lisa’s Lodge

Blessed Haven - king bed guest house
Guest house rentals with a patio

Cozy Rustic Lakefront Cabin

Modern Studio near downtown

Yes please we need you! Spacious w/ amazing view!

Starswept Studio–Near GSMNP, BRP, Food and Skiing

Downtown guest house with private hot tub & deck

Restful Refuge

Carriage House Suite on Lake Wylie

The Woodlen: Studio with Views/Hot tub/ fire pit
Guest house rentals with a washing machine and dryer

Upscale cottage in Downtown Fountain Inn

MeadowHill Guesthouse - Mountain view-3 mi to town

⭐️⭐️⭐️⭐️⭐️Casita Blanca 🚶🏽➡️Dining, BREWS,SHOPS📍DTWN📍LUX

The Guest House By The River

Private North Asheville Bungalow No Cleaning fees

Tryon Foothills Getaway - NC wineries! - TIEC

Lit'l Bit O' Heaven- Rocky Top Lodge

Private-Lake getaway-7 mile view from dock
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- Blue Ridge Parkway
- The North Carolina Arboretum
- Gorges State Park
- Table Rock State Park
- Chimney Rock State Park
- Ski Sapphire Valley
- Lake Lure Beach and Water Park
- Jump Off Rock
- Tryon International Equestrian Center
- Wade Hampton Golf Club
- Victoria Valley Vineyards
- Discovery Island
- Haas Family Golf
- Carl Sandburg Home National Historic Site
- Saint Paul Mountain Vineyards
- City Scape Winery
- Burntshirt Vineyards
- Overmountain Vineyards
- Wellborn Winery
- Russian Chapel Hills Winery
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